• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pap-2685
CNOT6

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: CNOT6
Ensembl Gene: ENSPPAG00000032253.1
Ensembl Protein: ENSPPAP00000018255.1
Organism: Pan paniscus
Taxa ID: 9597
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granule, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPKEKYEPPD  PRRMYTIMSS  EEAANGKKSH  WAELEISGKV  RSLSASLWSL  THLTALHLSD  60
61    NSLSRIPSDI  AKLHNLVYLD  LSSNKIRSLP  AELGNMVSLR  ELHLNNNLLR  VLPFELGKLF  120
121   QLQTLGLKGN  PLTQDILNLY  QEPDGTRRLL  NYLLDNLSGT  AKRITTEQPP  PRSWIMLQEP  180
181   DRTRPTALFS  VMCYNVLCDK  YATRQLYGYC  PSWALNWDYR  KKAIIQEILS  CNADIVSLQE  240
241   VETEQYYSFF  LVELKERGYN  GFFSPKSRAR  TMSEQERKHV  DGCAIFFKTE  KFTLVQKHTV  300
301   EFNQLAMANS  EGSEAMLNRV  MTKDNIGVAV  LLELRKESIE  MPSGKPHLGT  EKQLILVANA  360
361   HMHWDPEYSD  VKLVQTMMFL  SEVKNIIDKA  SRNLKSSVLG  EFGTIPLVLC  ADLNSLPDSG  420
421   VVEYLSTGGV  ETNHKDFKEL  RYNESLTNFS  CHGKNGTTNG  RITHGFKLQS  AYESGLMPYT  480
481   NYTFDFKGII  DYIFYSKPQL  NTLGILGPLD  HHWLVENNIS  GCPHPLIPSD  HFSLFAQLEL  540
541   LLPFLPQVNG  IHLPGRR  557
Nucleotide CDS Sequence (FASTA)
1     ATGCCCAAAG  AAAAATACGA  GCCCCCTGAC  CCTCGGAGGA  TGTATACAAT  TATGTCTTCT  60
61    GAGGAAGCAG  CAAATGGAAA  GAAATCCCAC  TGGGCAGAGC  TTGAAATAAG  TGGAAAAGTA  120
121   AGAAGCTTAA  GCGCATCTTT  GTGGTCACTA  ACTCACCTGA  CAGCTTTGCA  TTTGAGTGAC  180
181   AATTCCCTGT  CCCGAATTCC  TTCAGACATT  GCCAAGCTTC  ACAATCTGGT  GTATTTGGAC  240
241   CTGTCATCTA  ATAAAATTCG  TAGCTTACCC  GCAGAACTCG  GAAACATGGT  ATCACTCAGG  300
301   GAGCTCCATT  TAAATAACAA  CCTGTTACGA  GTTCTACCTT  TTGAGCTGGG  AAAACTGTTT  360
361   CAGTTGCAGA  CTTTAGGCCT  GAAAGGAAAT  CCCCTTACCC  AGGATATATT  GAACCTTTAT  420
421   CAGGAACCAG  ATGGAACAAG  ACGGCTGCTG  AACTATTTGC  TTGATAATTT  GTCAGGTACT  480
481   GCAAAAAGAA  TTACAACAGA  ACAACCACCT  CCAAGGTCTT  GGATTATGTT  ACAAGAACCA  540
541   GATAGGACAA  GGCCAACTGC  CTTGTTTTCT  GTCATGTGCT  ATAATGTTCT  TTGTGATAAA  600
601   TATGCGACCC  GGCAGTTATA  CGGCTACTGT  CCATCGTGGG  CGCTAAACTG  GGACTACAGG  660
661   AAAAAGGCCA  TTATTCAAGA  AATCTTGAGC  TGCAATGCTG  ATATCGTAAG  TCTTCAGGAG  720
721   GTTGAAACGG  AACAGTATTA  CAGTTTTTTT  CTGGTAGAGC  TGAAAGAACG  TGGCTATAAT  780
781   GGATTCTTCA  GTCCTAAGTC  TAGAGCTAGG  ACAATGTCAG  AACAAGAAAG  GAAACATGTT  840
841   GATGGCTGTG  CAATATTCTT  CAAGACAGAA  AAATTTACTT  TGGTTCAGAA  ACACACTGTT  900
901   GAATTTAATC  AGCTAGCCAT  GGCAAATTCT  GAGGGGTCTG  AAGCTATGCT  GAACAGAGTC  960
961   ATGACAAAAG  ATAACATTGG  GGTTGCAGTA  CTGCTAGAAC  TTCGGAAGGA  ATCGATTGAA  1020
1021  ATGCCGTCTG  GAAAGCCACA  TCTTGGAACA  GAAAAACAAC  TTATTCTTGT  GGCTAATGCC  1080
1081  CACATGCATT  GGGACCCTGA  ATACTCTGAT  GTGAAGTTGG  TACAAACTAT  GATGTTCCTC  1140
1141  TCAGAAGTGA  AGAACATTAT  TGATAAAGCC  TCTCGCAACC  TCAAATCCAG  TGTTTTGGGA  1200
1201  GAATTTGGAA  CTATTCCACT  TGTGTTATGT  GCAGATCTTA  ATTCTTTGCC  AGACTCTGGT  1260
1261  GTTGTAGAAT  ATTTGAGCAC  AGGTGGAGTA  GAAACAAATC  ACAAAGACTT  TAAGGAGTTG  1320
1321  AGGTATAATG  AAAGTCTCAC  AAACTTCAGC  TGTCATGGGA  AGAATGGAAC  CACCAATGGA  1380
1381  AGGATCACTC  ATGGTTTCAA  GCTACAGAGT  GCCTATGAGA  GTGGCCTGAT  GCCTTACACG  1440
1441  AATTACACAT  TTGATTTCAA  GGGTATAATC  GACTACATTT  TCTATTCTAA  ACCTCAGCTG  1500
1501  AACACCTTAG  GCATCCTGGG  CCCTCTGGAC  CACCACTGGC  TGGTTGAGAA  TAACATCAGT  1560
1561  GGCTGCCCGC  ACCCCCTCAT  CCCCTCTGAC  CACTTCTCAC  TTTTTGCACA  ACTGGAGCTC  1620
1621  TTACTGCCTT  TCCTGCCCCA  AGTCAACGGC  ATCCACCTTC  CTGGCAGGAG  GTAG  1674

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gog-1947Gorilla gorilla100.00.01092
LLPS-Hos-0539Homo sapiens100.00.01092
LLPS-Pat-0260Pan troglodytes100.00.01092
LLPS-Mal-2287Mandrillus leucophaeus99.640.01089
LLPS-Paa-1004Papio anubis99.640.01089
LLPS-Maf-1320Macaca fascicularis99.640.01089
LLPS-Chs-1748Chlorocebus sabaeus99.640.01089
LLPS-Cea-1942Cercocebus atys99.640.01089
LLPS-Mam-1124Macaca mulatta99.640.01089
LLPS-Man-0460Macaca nemestrina99.640.01089
LLPS-Poa-0339Pongo abelii99.440.01030
LLPS-Aon-0008Aotus nancymaae98.920.01080
LLPS-Caj-1408Callithrix jacchus98.740.01080
LLPS-Nol-1357Nomascus leucogenys98.560.01072
LLPS-Caf-2035Canis familiaris98.030.01053
LLPS-Fec-2279Felis catus98.030.01053
LLPS-Mup-0127Mustela putorius furo97.850.01051
LLPS-Eqc-1162Equus caballus97.850.01049
LLPS-Bot-2532Bos taurus97.490.01047
LLPS-Loa-3460Loxodonta africana97.490.01048
LLPS-Tut-0685Tursiops truncatus97.310.01047
LLPS-Sus-2456Sus scrofa97.130.01043
LLPS-Ict-4086Ictidomys tridecemlineatus97.130.01045
LLPS-Aim-2005Ailuropoda melanoleuca96.960.01048
LLPS-Ere-0227Erinaceus europaeus96.590.01030
LLPS-Otg-3474Otolemur garnettii96.560.0 973
LLPS-Mum-4844Mus musculus96.230.01032
LLPS-Cas-3456Carlito syrichta96.230.01034
LLPS-Mea-1432Mesocricetus auratus96.050.01031
LLPS-Ova-0024Ovis aries95.940.01000
LLPS-Mod-1701Monodelphis domestica95.870.01038
LLPS-Sah-0341Sarcophilus harrisii95.690.01035
LLPS-Gaga-2284Gallus gallus95.690.01055
LLPS-Anp-1269Anas platyrhynchos95.690.01053
LLPS-Fia-2979Ficedula albicollis95.690.01055
LLPS-Pes-2245Pelodiscus sinensis95.590.01004
LLPS-Orc-3702Oryctolagus cuniculus95.530.01049
LLPS-Fud-2427Fukomys damarensis95.510.01026
LLPS-Tag-0345Taeniopygia guttata95.330.01045
LLPS-Ran-1667Rattus norvegicus95.150.01009
LLPS-Ora-0935Ornithorhynchus anatinus94.970.01037
LLPS-Rhb-0011Rhinopithecus bieti94.690.01070
LLPS-Myl-1165Myotis lucifugus94.480.01024
LLPS-Urm-3464Ursus maritimus93.320.01038
LLPS-Anc-0144Anolis carolinensis93.00.01003
LLPS-Cap-1032Cavia porcellus92.10.0 970
LLPS-Leo-1723Lepisosteus oculatus89.960.0 992
LLPS-Scf-0489Scleropages formosus87.990.0 968
LLPS-Dio-3119Dipodomys ordii86.540.0 895
LLPS-Asm-3357Astyanax mexicanus86.380.0 958
LLPS-Icp-0715Ictalurus punctatus85.480.0 943
LLPS-Xim-0488Xiphophorus maculatus85.30.0 951
LLPS-Orl-1971Oryzias latipes84.790.0 944
LLPS-Pof-1547Poecilia formosa84.770.0 944
LLPS-Scm-2052Scophthalmus maximus84.440.0 944
LLPS-Ten-1160Tetraodon nigroviridis84.380.0 944
LLPS-Tar-0935Takifugu rubripes84.020.0 937
LLPS-Dar-3772Danio rerio83.510.0 933
LLPS-Gaa-0161Gasterosteus aculeatus82.990.0 888
LLPS-Meg-0114Meleagris gallopavo77.20.0 853
LLPS-Xet-0868Xenopus tropicalis76.480.0 851
LLPS-Lac-3428Latimeria chalumnae75.760.0 842
LLPS-Orn-1143Oreochromis niloticus73.980.0 830
LLPS-Drm-0808Drosophila melanogaster57.740.0 606
LLPS-Cii-0774Ciona intestinalis56.720.0 600
LLPS-Cis-0245Ciona savignyi48.421e-59 206
LLPS-Cae-0204Caenorhabditis elegans48.015e-119 374
LLPS-Pug-0674Puccinia graminis43.247e-126 395
LLPS-Mel-0784Melampsora laricipopulina42.44e-131 401
LLPS-Miv-0216Microbotryum violaceum41.841e-119 374
LLPS-Spr-0223Sporisorium reilianum41.324e-114 364
LLPS-Usm-0048Ustilago maydis41.132e-117 370
LLPS-Scj-0744Schizosaccharomyces japonicus39.965e-89 293
LLPS-Scc-0001Schizosaccharomyces cryophilus38.997e-107 342
LLPS-Scp-0007Schizosaccharomyces pombe38.78e-111 352
LLPS-Abg-0847Absidia glauca38.192e-104 336
LLPS-Crn-1086Cryptococcus neoformans37.892e-105 340
LLPS-Tum-0415Tuber melanosporum37.193e-105 338
LLPS-Asni-0487Aspergillus niger37.044e-93 305
LLPS-Ved-0009Verticillium dahliae36.871e-87 291
LLPS-Phn-0856Phaeosphaeria nodorum36.72e-94 307
LLPS-Aso-0154Aspergillus oryzae36.658e-91 301
LLPS-Asf-1022Aspergillus flavus36.659e-91 301
LLPS-Asc-1087Aspergillus clavatus36.521e-91 302
LLPS-Kop-0939Komagataella pastoris36.423e-88 295
LLPS-Asn-0994Aspergillus nidulans36.236e-94 308
LLPS-Ast-0904Aspergillus terreus36.219e-91 300
LLPS-Blg-0064Blumeria graminis36.135e-94 310
LLPS-Sac-0068Saccharomyces cerevisiae35.78e-86 290
LLPS-Lem-0460Leptosphaeria maculans35.589e-102 331
LLPS-Pyt-1156Pyrenophora teres35.526e-98 320
LLPS-Yal-0096Yarrowia lipolytica35.523e-93 306
LLPS-Fus-0280Fusarium solani35.52e-83 281
LLPS-Asg-0080Ashbya gossypii35.473e-85 286
LLPS-Cogr-0440Colletotrichum graminicola35.452e-86 290
LLPS-Trv-0622Trichoderma virens35.422e-84 283
LLPS-Php-2457Physcomitrella patens35.361e-52 195
LLPS-Fuv-1276Fusarium verticillioides35.322e-82 275
LLPS-Fuo-0050Fusarium oxysporum35.321e-82 276
LLPS-Beb-0498Beauveria bassiana35.252e-87 291
LLPS-Trr-0660Trichoderma reesei35.245e-85 285
LLPS-Nef-0691Neosartorya fischeri35.231e-90 301
LLPS-Cog-0490Colletotrichum gloeosporioides35.176e-86 289
LLPS-Hea-2541Helianthus annuus35.132e-52 192
LLPS-Gag-0103Gaeumannomyces graminis35.027e-81 275
LLPS-Mao-0084Magnaporthe oryzae34.944e-82 278
LLPS-Map-0971Magnaporthe poae34.721e-80 275
LLPS-Asfu-0676Aspergillus fumigatus34.64e-91 301
LLPS-Coo-0985Colletotrichum orbiculare34.323e-82 278
LLPS-Zyt-0438Zymoseptoria tritici33.94e-85 285
LLPS-Met-1310Medicago truncatula33.732e-46 176
LLPS-Mua-1776Musa acuminata33.593e-53 196
LLPS-Scs-0965Sclerotinia sclerotiorum33.583e-82 276
LLPS-Nec-0051Neurospora crassa33.511e-83 283
LLPS-Glm-1367Glycine max33.332e-48 182
LLPS-Vir-0997Vigna radiata33.248e-48 177
LLPS-Sem-1014Selaginella moellendorffii33.157e-49 183
LLPS-Osl-0467Ostreococcus lucimarinus33.084e-52 193
LLPS-Chc-0558Chondrus crispus33.077e-51 184
LLPS-Phv-2585Phaseolus vulgaris33.061e-47 180
LLPS-Mae-2177Manihot esculenta32.983e-49 184
LLPS-Cym-0558Cyanidioschyzon merolae32.958e-49 184
LLPS-Via-0970Vigna angularis32.791e-47 180
LLPS-Chr-0224Chlamydomonas reinhardtii32.794e-52 192
LLPS-Thc-0186Theobroma cacao32.542e-48 182
LLPS-Gor-1348Gossypium raimondii32.545e-49 184
LLPS-Coc-1129Corchorus capsularis32.281e-46 177
LLPS-Art-2575Arabidopsis thaliana32.254e-48 181
LLPS-Dac-0501Daucus carota32.172e-47 180
LLPS-Bro-0829Brassica oleracea32.166e-45 172
LLPS-Pot-0120Populus trichocarpa32.166e-48 181
LLPS-Nia-0292Nicotiana attenuata32.111e-46 177
LLPS-Orbr-1901Oryza brachyantha32.087e-45 172
LLPS-Dos-0056Dothistroma septosporum32.032e-79 271
LLPS-Sol-1860Solanum lycopersicum31.993e-47 179
LLPS-Arl-0025Arabidopsis lyrata31.985e-47 178
LLPS-Sot-0960Solanum tuberosum31.726e-47 178
LLPS-Orgl-0884Oryza glumaepatula31.611e-43 169
LLPS-Orb-2374Oryza barthii31.616e-44 169
LLPS-Ori-0303Oryza indica31.616e-44 169
LLPS-Orni-1819Oryza nivara31.616e-44 169
LLPS-Orm-0086Oryza meridionalis31.615e-44 169
LLPS-Orr-1996Oryza rufipogon31.616e-44 169
LLPS-Org-0844Oryza glaberrima31.616e-44 169
LLPS-Ors-1694Oryza sativa31.616e-44 169
LLPS-Brn-1094Brassica napus31.596e-47 178
LLPS-Brr-1605Brassica rapa31.596e-47 178
LLPS-Orp-0318Oryza punctata31.278e-44 169
LLPS-Viv-0644Vitis vinifera31.182e-46 176
LLPS-Cus-1403Cucumis sativus31.171e-46 177
LLPS-Prp-0636Prunus persica31.084e-46 176
LLPS-Sob-1823Sorghum bicolor31.079e-44 169
LLPS-Zem-0329Zea mays31.022e-42 165
LLPS-Amt-1291Amborella trichopoda30.983e-46 176
LLPS-Tra-1068Triticum aestivum30.874e-43 167
LLPS-Sei-1053Setaria italica30.711e-42 165
LLPS-Brd-1621Brachypodium distachyon30.715e-43 166
LLPS-Hov-0997Hordeum vulgare30.62e-42 165
LLPS-Tru-0764Triticum urartu30.62e-42 165
LLPS-Lep-0083Leersia perrieri30.549e-43 166
LLPS-Gas-0431Galdieria sulphuraria30.057e-43 166