LLPS-Paa-a372
CNN3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Calponin |
| Gene Name: | CNN3 |
| Ensembl Gene: | ENSPANG00000013361.2 |
| Ensembl Protein: | ENSPANP00000001445.1 |
| Organism: | Papio anubis |
| Taxa ID: | 9555 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPANT00000028312.2 | ENSPANP00000001445.1 |
| Ensembl | ENSPANT00000049482.1 | ENSPANP00000031375.1 |
| Ensembl | ENSPANT00000048491.1 | ENSPANP00000022568.1 |
| Ensembl | ENSPANT00000048236.1 | ENSPANP00000037689.1 |
| UniProt | A0A096MP12, A0A096MP12_PAPAN | |
| GeneBank | AHZZ02016395 | |
| RefSeq | XM_003892230.2 | XP_003892279.1 |
| Entrez | 101021426 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTHFNKGPSY GLSAEVKNKI ASKYDHQAEE DLRNWIEEVT GMSIGTNFQL GLKDGIILCE 60 61 LINKLQPGSV KKVNESSLNW PQLENIGNFI KAIQAYGMKP HDIFEANDLF ENGNMTQVQT 120 121 TLVALAGLAK TKGFHTTIDI GVKYAEKQTR RFDEGKLKAG QSVIGLQMGT NKCASQAGMT 180 181 AYGTRRHLYD PKMQTDKPFD QTTISLQMGT NKGASQAGML APGTRRDIYD QKLTLQPVDN 240 241 STISLQMGTN KVASQKGMSV YGLGRQVYDP KYCAAPTEPV IHNGSQGTGT NGSEISDSDY 300 301 QAEYPDEYHG EYQDDYPRDY QYSDQGIDY 329 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Actin cytoskeleton | |
Cellular Component | Cytosol | |
Molecular Function | Actin binding | |
Molecular Function | Calmodulin binding | |
Biological Process | Actomyosin structure organization | |
Biological Process | Epithelial cell differentiation |