LLPS-Otg-a315
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Vacuolar protein sorting-associated protein 29; Vesicle protein sorting 29 |
| Ensembl Gene: | ENSOGAG00000006985.2 |
| Ensembl Protein: | ENSOGAP00000006251.2 |
| Organism: | Otolemur garnettii |
| Taxa ID: | 30611 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOGAT00000006986.2 | ENSOGAP00000006251.2 |
| UniProt | H0WVC1, H0WVC1_OTOGA | |
| GeneBank | AAQR03124292 | |
| Entrez | 100956308 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 LDTLKLVLVL GDLHIPHRCN SLPAKFKKLL VPGKIQHILC TGNLCTKESY DYLKTLAGDV 60 61 HIVRGDFDEN LNYPEQKVVT VGQFKIGLIH GHQVIPWGDM ASLALLQRQF DVDILISGHT 120 121 HKFEAFEHEN KFYINPGSAT GAYNALETNI IPSFVLMDIQ ASTVVTYVYQ LIGDDVKVER 180 181 IEYKKS 186 |
| Nucleotide CDS Sequence (FASTA) |
1 CTTGACACTT TAAAGTTGGT GTTGGTATTA GGAGATCTGC ACATCCCACA CCGGTGCAAC 60 61 AGTTTGCCAG CTAAATTCAA AAAACTTCTA GTACCAGGAA AGATTCAGCA CATTCTCTGC 120 121 ACAGGAAACC TTTGCACCAA AGAGAGTTAT GACTACCTCA AGACTCTGGC TGGTGATGTC 180 181 CATATTGTGA GAGGAGACTT CGATGAGAAT CTGAATTATC CAGAACAGAA AGTTGTGACT 240 241 GTTGGACAAT TCAAAATTGG TTTGATCCAT GGACATCAAG TTATTCCATG GGGAGACATG 300 301 GCCAGCTTAG CCCTGTTGCA GAGGCAGTTT GATGTGGACA TTCTTATCTC GGGACACACA 360 361 CACAAATTTG AAGCATTTGA GCATGAAAAT AAGTTCTACA TTAACCCAGG TTCTGCCACT 420 421 GGAGCATATA ATGCCTTGGA AACAAACATT ATCCCATCAT TTGTGTTGAT GGATATCCAA 480 481 GCTTCCACAG TGGTCACTTA TGTATATCAG CTCATTGGAG ATGACGTGAA AGTAGAACGA 540 541 ATTGAATATA AAAAGTCGTA A 561 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Retromer complex | |
Biological Process | Protein transport | |
Biological Process | Retrograde transport, endosome to Golgi |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a317 | Homo sapiens | 1e-130 | 375 | undefined |
| LLPS-Mum-a317 | Mus musculus | 1e-131 | 376 | undefined |