LLPS-Otg-4651
AKAP12
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | A-kinase anchoring protein 12 |
| Gene Name: | AKAP12 |
| Ensembl Gene: | ENSOGAG00000011277.2 |
| Ensembl Protein: | ENSOGAP00000010098.2 |
| Organism: | Otolemur garnettii |
| Taxa ID: | 30611 |
| LLPS Type: | Client |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOGAT00000011282.2 | ENSOGAP00000010098.2 |
| UniProt | H0X4H0, H0X4H0_OTOGA | |
| GeneBank | AAQR03140303, AAQR03140301, AAQR03140300, AAQR03140302 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 VLLTVGQRDS EDVSERDASK EMAANSEVVH DITSDEQEMP EITEQVPSSE SNLEELTQPT 60 61 ESQANDIGFK KVFKFVGLKF TVKKDKSEKS DTVQLLTVKK DEGEGAAGAG DHPEPSWEAG 120 121 ETAAKESEFQ QSTEKPQGAL KQEQTHTEIS LQAQFGQAAV EGKDEGEVKE KKEKESSKSP 180 181 ESPTSPVTSE TTSSFKKFFI QGWAGWRKKT SFKKPKEEEL EASEKKKGPE PEKADTEDKE 240 241 KVEASSEKPT APEQPLSVEV MKGAQEARLS AEYEKVELPL EDQGNGLQAS LAEKLAPLAT 300 301 EVFDEKVEVQ QEVIADVHIS TEEHTEEQEA EVEETVESLP PVEIDAEPQE AEAAKEPVKA 360 361 EEVCAPGEDH SQEPEPSCDE KVLPRHPEGL ISEVEMLSSQ ERTKVQGSPL KKLFTSTGLK 420 421 KLSGKKQKGK RGGGGDEESG EQSHIPADSP DSNDEQKGES SASSPEEPEE ITCLEKGIAD 480 481 TPPEVEVEEG PTSDGEKKRE GVTPWASFKK MVTPKKRVRR PSESDKEDEL DKVKSATLSS 540 541 TESAASEIQE EVKGSAEEQK PEEPKRKVDT SVSWEALICV GSSKKRARKA SSSDEEGAPR 600 601 TLGGDSQRAD EAGKDKEPGT EAMLASSQEH DPGRGSSSPE QAGSPSEGEG VSTWESFKRL 660 661 VTARKKSKSK LEEKNEDSLT GSGIEHSASD VEPGKEESWV SIKKFMPGRR KKRPDGKQEP 720 721 GVIEDTGTTE VNEDDADVPA VVPLSEYDAV EMEKMEAQQA QKSADKPEQM ANVDVSEELS 780 781 KRLVHTVAAA VLDGTRAGTN VEERSPSWIS ASVTEPVEQT EEGEATPLTG EVFGREVIAE 840 841 EIPMVSTPVP ENRDACDNLF ISEVQVTSEA VTAAETTEAF CAEEAAERSG AEETTEMVSA 900 901 VSQLTDSPDT TEEVTPVQEV EGGVPGVDEQ ERRTQEVLQA VAEKVKEESQ LHGTIGPEDT 960 961 IQTMQKVESE LPEKLEEAEE DSKALGLETE MDVVLKVHTQ QTKPEHFTQG EEVQATPESL 1020 1021 EEALQFTESV ESSELITTGQ AETLAGVKSQ EIIVEQAIPP DSVETPTGSE TSGSAPVADL 1080 1081 EALDTAQQDE IVETQEDEEV ASRTQPGVPE AESVPAQKER LLAPSDLQSQ EEKKEQTKVE 1140 1141 DVPEHTDEEV SMETEPILKT EVMQQAGQCV DEETRDTPFV RGLEVSVDRD VMVSQEKVTE 1200 1201 VALKDEVLKE AECEKNGTVE LQSPTKSLPS PVETEMVVEV KEDEVKAETA QVSEEKLEQK 1260 1261 TAVSISEEPS VSEVVSVQLV QTFDVTVMDG EKEVSHVEGS PVPCLGEEEA ICTEVQGQSS 1320 1321 EASLTLSAAM VEEKVLGEAV KILEMAETLE SAGAHLVLEE KPTEKDEDFT ALPGGEAEPT 1380 1381 GPGSQAESIT EITSATSEKS LCSDLEGEKT TSLKRKSDEV SEQDEYQEVR VSVARQEDLK 1440 1441 AGDEVLELET ESSKLVRNVI QTAVDQFVHT EETAIEALTS DLQTQAHLVK AESQGAGQKT 1500 1501 EKEESEWKAP AQDETQTSAV KEEAELSAGR PVHSDVSRDV SDTSEKTTEV ESSSVNDQQL 1560 1561 EEILLPSEKA GDGTGTQSMP EDDGGAVLEE GIEKSQFESK EDEKGEAVDY HESPSSALAD 1620 1621 TYTSGDLTKE SSDTNGLTRK EEDAQEAELQ EGKVLSESDK EIKTQTQEET EKQERESAKP 1680 1681 ELQES 1685 |
| Nucleotide CDS Sequence (FASTA) |
1 GTTTTGTTAA CAGTTGGGCA GAGAGACTCT GAAGATGTGA GTGAAAGAGA CGCCAGTAAA 60 61 GAGATGGCTG CTAACTCAGA GGTGGTTCAT GACATCACAA GTGACGAGCA GGAGATGCCT 120 121 GAAATAACTG AGCAGGTTCC TTCTTCAGAA AGCAATTTAG AAGAGTTAAC ACAACCTACT 180 181 GAGTCCCAGG CTAATGATAT CGGGTTTAAG AAGGTGTTTA AGTTTGTGGG CCTTAAATTC 240 241 ACTGTGAAAA AGGATAAGAG TGAGAAGTCT GACACTGTCC AACTGCTCAC TGTCAAGAAA 300 301 GATGAAGGCG AGGGAGCAGC TGGGGCAGGC GACCATCCAG AGCCAAGCTG GGAGGCAGGG 360 361 GAGACTGCTG CCAAAGAAAG TGAGTTCCAG CAGTCCACAG AGAAACCCCA GGGGGCCCTC 420 421 AAGCAAGAGC AAACCCACAC AGAAATTTCT CTTCAAGCTC AATTTGGGCA AGCAGCAGTG 480 481 GAAGGCAAGG ATGAAGGAGA AGTCAAAGAG AAAAAGGAAA AAGAGTCCAG CAAGTCCCCA 540 541 GAGTCCCCAA CTAGTCCAGT GACCAGCGAA ACAACATCTT CCTTCAAGAA ATTCTTCATT 600 601 CAAGGTTGGG CCGGCTGGCG GAAGAAGACC AGTTTCAAGA AGCCAAAGGA GGAGGAACTG 660 661 GAAGCCTCAG AGAAGAAAAA GGGACCAGAG CCAGAAAAGG CAGACACAGA GGACAAAGAA 720 721 AAGGTAGAAG CCAGCTCTGA GAAACCTACC GCTCCTGAAC AGCCACTCTC AGTGGAGGTA 780 781 ATGAAAGGTG CTCAGGAGGC CAGACTATCA GCCGAGTATG AGAAAGTAGA GCTGCCCTTG 840 841 GAAGACCAAG GCAATGGCTT GCAGGCATCT CTTGCAGAGA AACTCGCGCC GTTGGCAACA 900 901 GAAGTCTTTG ATGAAAAAGT AGAAGTCCAG CAAGAAGTTA TTGCAGATGT GCACATCAGC 960 961 ACTGAGGAGC ACACGGAGGA GCAGGAGGCC GAGGTGGAGG AGACAGTAGA GTCTTTGCCT 1020 1021 CCAGTAGAAA TAGATGCTGA ACCTCAGGAA GCTGAAGCTG CCAAGGAGCC AGTAAAGGCT 1080 1081 GAAGAAGTTT GTGCCCCTGG AGAGGACCAC TCCCAGGAGC CTGAACCAAG CTGTGATGAA 1140 1141 AAAGTGTTGC CCAGACATCC AGAAGGCCTT ATAAGTGAGG TGGAGATGTT GTCCTCCCAG 1200 1201 GAGAGGACTA AGGTGCAGGG AAGTCCACTG AAGAAACTTT TTACCAGCAC TGGCTTAAAA 1260 1261 AAACTTTCTG GAAAGAAGCA GAAAGGGAAA AGAGGAGGAG GAGGAGATGA AGAGTCTGGG 1320 1321 GAGCAGAGTC ACATTCCAGC AGATTCTCCA GATAGTAACG ATGAGCAAAA GGGCGAGAGC 1380 1381 TCTGCATCCT CCCCTGAGGA GCCTGAGGAG ATCACCTGCC TGGAGAAGGG GATAGCAGAC 1440 1441 ACGCCTCCTG AGGTAGAAGT TGAAGAAGGA CCCACTTCTG ATGGTGAAAA GAAAAGAGAG 1500 1501 GGCGTTACTC CCTGGGCGTC TTTCAAAAAG ATGGTGACAC CCAAGAAACG TGTCAGAAGG 1560 1561 CCTTCCGAAA GTGATAAAGA AGATGAGCTG GACAAGGTGA AAAGTGCCAC CCTGTCCTCC 1620 1621 ACAGAGAGCG CAGCCTCTGA GATTCAAGAA GAAGTCAAAG GAAGTGCAGA AGAGCAAAAG 1680 1681 CCAGAAGAAC CGAAGCGCAA GGTGGATACT TCAGTGTCTT GGGAAGCTTT GATCTGTGTG 1740 1741 GGATCATCCA AGAAAAGGGC AAGAAAAGCA TCATCTTCTG ATGAGGAGGG AGCCCCAAGG 1800 1801 ACATTGGGAG GAGACAGCCA AAGAGCAGAT GAGGCTGGAA AAGACAAAGA ACCAGGAACC 1860 1861 GAGGCCATGC TGGCTAGTTC CCAAGAACAT GACCCAGGGC GAGGAAGCTC CTCACCCGAG 1920 1921 CAAGCTGGAA GCCCTTCTGA AGGGGAGGGC GTCTCCACTT GGGAGTCATT TAAAAGATTG 1980 1981 GTCACTGCAA GAAAAAAGTC CAAGTCAAAA CTGGAAGAGA AAAATGAAGA CTCATTGACT 2040 2041 GGGTCTGGAA TAGAACATTC GGCTTCAGAT GTTGAACCTG GGAAAGAGGA ATCGTGGGTC 2100 2101 TCAATCAAGA AGTTTATGCC TGGACGAAGG AAAAAAAGGC CAGATGGGAA ACAAGAACCA 2160 2161 GGCGTTATTG AAGATACAGG GACAACAGAG GTCAATGAAG ACGATGCTGA CGTTCCAGCT 2220 2221 GTGGTCCCTC TGTCTGAATA TGATGCGGTA GAAATGGAGA AAATGGAAGC ACAGCAAGCC 2280 2281 CAAAAAAGTG CGGATAAGCC TGAGCAGATG GCCAATGTTG ATGTATCTGA GGAGCTCAGT 2340 2341 AAGAGGTTGG TTCACACAGT GGCTGCGGCT GTCCTTGATG GAACCAGGGC AGGTACCAAT 2400 2401 GTTGAAGAGA GGTCTCCTTC TTGGATATCT GCTTCCGTGA CCGAACCTGT TGAACAAACA 2460 2461 GAAGAAGGTG AAGCCACACC ATTAACTGGG GAGGTGTTTG GAAGAGAAGT GATTGCTGAA 2520 2521 GAAATCCCCA TGGTTTCCAC ACCTGTGCCA GAGAACAGAG ATGCCTGTGA CAACTTGTTC 2580 2581 ATCAGTGAGG TGCAAGTAAC TTCTGAAGCT GTGACAGCTG CAGAAACAAC AGAGGCATTT 2640 2641 TGTGCTGAAG AAGCAGCCGA AAGATCGGGT GCTGAAGAGA CCACAGAAAT GGTGTCAGCA 2700 2701 GTTTCCCAGT TAACCGACTC TCCGGATACC ACAGAGGAAG TGACACCAGT TCAGGAGGTA 2760 2761 GAAGGTGGTG TGCCAGGCGT AGACGAGCAA GAGAGGCGGA CTCAAGAGGT TCTACAGGCG 2820 2821 GTTGCAGAAA AAGTGAAAGA GGAATCCCAG CTGCATGGCA CCATTGGGCC AGAAGACACA 2880 2881 ATTCAGACCA TGCAGAAAGT AGAATCAGAA CTACCAGAGA AGCTGGAAGA AGCAGAGGAA 2940 2941 GATTCTAAAG CATTAGGCCT AGAGACAGAG ATGGATGTAG TGTTGAAAGT GCATACACAA 3000 3001 CAGACTAAAC CTGAGCATTT TACACAAGGG GAGGAGGTAC AGGCCACCCC AGAAAGCTTA 3060 3061 GAAGAAGCTC TTCAATTCAC AGAGAGTGTA GAGTCCAGTG AACTTATAAC CACTGGTCAA 3120 3121 GCTGAAACCT TAGCTGGGGT AAAATCACAG GAGATTATAG TAGAACAAGC TATCCCCCCT 3180 3181 GACTCAGTTG AAACCCCGAC AGGCAGTGAG ACCAGTGGAA GTGCCCCAGT AGCAGATCTG 3240 3241 GAAGCTCTAG ATACAGCACA GCAAGATGAG ATTGTGGAAA CCCAGGAAGA TGAAGAGGTT 3300 3301 GCATCCAGAA CCCAACCAGG GGTCCCAGAA GCAGAGTCCG TTCCTGCACA GAAAGAGAGG 3360 3361 CTTCTAGCAC CTTCTGATCT TCAATCCCAG GAAGAAAAGA AAGAGCAAAC AAAAGTGGAA 3420 3421 GATGTTCCAG AACATACAGA TGAAGAGGTA TCCATGGAAA CTGAACCCAT TTTGAAGACT 3480 3481 GAAGTGATGC AACAGGCTGG CCAGTGTGTT GATGAAGAAA CCAGAGACAC ACCATTTGTC 3540 3541 AGAGGACTTG AAGTGTCTGT AGACAGAGAT GTGATGGTCA GTCAGGAAAA GGTCACTGAA 3600 3601 GTTGCTCTTA AAGATGAAGT GCTGAAAGAA GCTGAATGTG AAAAGAATGG CACTGTTGAA 3660 3661 CTCCAGAGTC CTACCAAGTC TCTGCCCTCC CCAGTGGAGA CAGAGATGGT AGTTGAGGTT 3720 3721 AAAGAGGATG AAGTTAAAGC AGAAACAGCC CAAGTGAGCG AAGAGAAACT TGAGCAAAAA 3780 3781 ACAGCTGTTA GCATATCTGA AGAACCCAGT GTATCTGAAG TGGTCAGCGT GCAACTGGTT 3840 3841 CAGACCTTTG ATGTGACTGT CATGGATGGG GAGAAGGAAG TTAGCCATGT GGAAGGAAGC 3900 3901 CCTGTTCCTT GCCTAGGTGA AGAGGAGGCA ATATGCACAG AAGTTCAAGG TCAGAGCTCT 3960 3961 GAGGCATCAT TAACTCTATC CGCTGCAATG GTGGAGGAGA AAGTTTTAGG AGAAGCTGTC 4020 4021 AAAATTTTAG AGATGGCTGA AACTTTGGAG TCTGCAGGTG CACATTTAGT ACTGGAAGAG 4080 4081 AAACCCACTG AAAAAGATGA AGACTTCACA GCTCTGCCAG GAGGAGAAGC TGAGCCTACA 4140 4141 GGGCCCGGGT CTCAGGCAGA ATCAATAACA GAAATAACAT CTGCCACTAG TGAAAAAAGC 4200 4201 TTATGTTCTG ACCTGGAAGG AGAGAAAACC ACATCACTGA AACGGAAGTC AGATGAAGTC 4260 4261 AGTGAGCAGG ATGAATACCA GGAAGTCAGA GTGAGTGTAG CAAGGCAGGA AGATTTAAAG 4320 4321 GCTGGTGATG AGGTTTTGGA ACTTGAGACT GAGAGCAGTA AACTCGTCAG AAACGTAATT 4380 4381 CAGACTGCCG TTGACCAGTT TGTACATACA GAAGAGACAG CCATCGAAGC ATTGACATCT 4440 4441 GATTTGCAGA CGCAGGCTCA CCTGGTGAAA GCCGAGAGCC AGGGAGCTGG ACAGAAAACA 4500 4501 GAGAAAGAAG AGAGTGAATG GAAGGCTCCT GCACAGGATG AAACCCAAAC TAGTGCTGTC 4560 4561 AAAGAGGAGG CAGAGCTGAG TGCCGGGAGA CCAGTGCATT CTGATGTTTC CAGAGATGTG 4620 4621 AGCGACACTT CAGAAAAGAC CACTGAAGTA GAGAGCTCCA GTGTAAATGA CCAGCAGCTT 4680 4681 GAAGAAATAC TTCTCCCATC CGAGAAAGCA GGAGATGGAA CTGGAACACA GTCTATGCCA 4740 4741 GAAGATGATG GTGGTGCTGT GTTAGAAGAA GGAATAGAGA AGTCACAGTT TGAATCCAAA 4800 4801 GAAGATGAAA AAGGTGAAGC TGTTGATTAC CATGAGAGCC CAAGCTCAGC CCTGGCAGAT 4860 4861 ACTTACACCT CAGGAGACTT AACCAAAGAG TCCTCAGATA CAAATGGACT GACACGAAAA 4920 4921 GAGGAGGATG CCCAGGAAGC AGAATTACAG GAAGGAAAAG TGCTCAGTGA GTCAGATAAA 4980 4981 GAGATCAAAA CCCAAACACA GGAGGAGACA GAGAAACAAG AGAGGGAATC AGCAAAGCCA 5040 5041 GAACTTCAAG AATCTTAA 5058 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Maf-4272 | Macaca fascicularis | 69.34 | 0.0 | 1576 |
| LLPS-Urm-3798 | Ursus maritimus | 69.24 | 7e-177 | 560 |
| LLPS-Gog-3855 | Gorilla gorilla | 69.21 | 0.0 | 1582 |
| LLPS-Mal-3301 | Mandrillus leucophaeus | 69.04 | 0.0 | 1566 |
| LLPS-Hos-2147 | Homo sapiens | 68.97 | 0.0 | 1580 |
| LLPS-Poa-1680 | Pongo abelii | 68.97 | 0.0 | 1593 |
| LLPS-Pat-2718 | Pan troglodytes | 68.44 | 0.0 | 1578 |
| LLPS-Mam-0866 | Macaca mulatta | 68.4 | 0.0 | 1570 |
| LLPS-Nol-4353 | Nomascus leucogenys | 68.36 | 0.0 | 1584 |
| LLPS-Cea-0714 | Cercocebus atys | 68.28 | 0.0 | 1573 |
| LLPS-Paa-3118 | Papio anubis | 68.28 | 0.0 | 1570 |
| LLPS-Man-2452 | Macaca nemestrina | 68.28 | 0.0 | 1564 |
| LLPS-Pap-0149 | Pan paniscus | 68.09 | 0.0 | 1569 |
| LLPS-Chs-2053 | Chlorocebus sabaeus | 67.98 | 0.0 | 1563 |
| LLPS-Rhb-2443 | Rhinopithecus bieti | 67.57 | 0.0 | 1538 |
| LLPS-Aon-1162 | Aotus nancymaae | 66.35 | 0.0 | 1465 |
| LLPS-Caj-4293 | Callithrix jacchus | 65.65 | 0.0 | 1440 |
| LLPS-Mea-4309 | Mesocricetus auratus | 64.51 | 2e-161 | 520 |
| LLPS-Loa-2813 | Loxodonta africana | 62.75 | 0.0 | 1263 |
| LLPS-Eqc-4700 | Equus caballus | 62.24 | 0.0 | 1340 |
| LLPS-Caf-4311 | Canis familiaris | 62.05 | 0.0 | 1219 |
| LLPS-Gaga-0981 | Gallus gallus | 61.38 | 2e-104 | 375 |
| LLPS-Myl-3839 | Myotis lucifugus | 60.96 | 0.0 | 1229 |
| LLPS-Meg-2535 | Meleagris gallopavo | 60.94 | 1e-107 | 372 |
| LLPS-Aim-2725 | Ailuropoda melanoleuca | 60.54 | 0.0 | 1224 |
| LLPS-Sus-0296 | Sus scrofa | 60.19 | 0.0 | 1162 |
| LLPS-Ova-4109 | Ovis aries | 59.78 | 0.0 | 900 |
| LLPS-Sah-4125 | Sarcophilus harrisii | 59.6 | 2e-10 | 70.5 |
| LLPS-Anp-2141 | Anas platyrhynchos | 59.53 | 1e-93 | 335 |
| LLPS-Mup-0299 | Mustela putorius furo | 59.4 | 0.0 | 1177 |
| LLPS-Orc-2176 | Oryctolagus cuniculus | 59.34 | 0.0 | 1220 |
| LLPS-Ict-1327 | Ictidomys tridecemlineatus | 59.31 | 0.0 | 1190 |
| LLPS-Bot-1876 | Bos taurus | 58.42 | 0.0 | 1142 |
| LLPS-Fia-3499 | Ficedula albicollis | 57.46 | 5e-106 | 380 |
| LLPS-Tag-3239 | Taeniopygia guttata | 56.81 | 3e-74 | 259 |
| LLPS-Cap-4062 | Cavia porcellus | 56.52 | 9e-12 | 74.7 |
| LLPS-Pes-3091 | Pelodiscus sinensis | 55.14 | 1e-06 | 58.2 |
| LLPS-Fud-2295 | Fukomys damarensis | 54.41 | 0.0 | 1018 |
| LLPS-Mum-4244 | Mus musculus | 53.99 | 0.0 | 959 |
| LLPS-Lac-2750 | Latimeria chalumnae | 52.14 | 1e-77 | 288 |
| LLPS-Ran-3163 | Rattus norvegicus | 51.95 | 0.0 | 941 |
| LLPS-Xet-3446 | Xenopus tropicalis | 51.91 | 6e-84 | 306 |
| LLPS-Anc-1883 | Anolis carolinensis | 51.49 | 1e-93 | 334 |
| LLPS-Mod-3671 | Monodelphis domestica | 49.37 | 9e-116 | 397 |
| LLPS-Leo-1706 | Lepisosteus oculatus | 48.58 | 3e-68 | 259 |
| LLPS-Ora-1772 | Ornithorhynchus anatinus | 47.63 | 6e-156 | 526 |
| LLPS-Dar-0283 | Danio rerio | 46.26 | 4e-43 | 177 |
| LLPS-Icp-4065 | Ictalurus punctatus | 44.9 | 3e-40 | 168 |
| LLPS-Asm-3835 | Astyanax mexicanus | 44.09 | 1e-38 | 162 |
| LLPS-Ten-1790 | Tetraodon nigroviridis | 41.7 | 5e-26 | 121 |
| LLPS-Orl-1400 | Oryzias latipes | 39.71 | 1e-08 | 64.3 |
| LLPS-Orn-3657 | Oreochromis niloticus | 37.94 | 4e-25 | 118 |
| LLPS-Scf-3113 | Scleropages formosus | 36.63 | 5e-09 | 65.9 |
| LLPS-Pof-3425 | Poecilia formosa | 35.88 | 5e-19 | 98.6 |
| LLPS-Scm-3524 | Scophthalmus maximus | 34.65 | 8e-26 | 120 |
| LLPS-Tar-0930 | Takifugu rubripes | 33.49 | 2e-29 | 132 |
| LLPS-Xim-0448 | Xiphophorus maculatus | 33.04 | 4e-20 | 102 |