DrLLPS - Data resource of LLPS

LLPS-Otg-2921
POLR2H

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	DNA-directed RNA polymerases I, II, and III subunit RPABC3
Gene Name:	POLR2H
Ensembl Gene:	ENSOGAG00000001599.2
Ensembl Protein:	ENSOGAP00000001423.2
Organism:	Otolemur garnettii
Taxa ID:	30611
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Mus musculus	LLPS-Mum-0782	Q923G2	Client	Nucleolus	100.00	9e-106	305
Saccharomyces cerevisiae	LLPS-Sac-0406	P20436	Client	Nucleolus	35.06	3e-20	86.7
Homo sapiens	LLPS-Hos-0617	P52434	Client	Nucleolus	100.00	1e-70	217

▼ FUNCTION

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSOGAT00000001600.2	ENSOGAP00000001423.2
UniProt		H0WIY6, H0WIY6_OTOGA
GeneBank	AAQR03181437, AAQR03181436
RefSeq	XM_003802870.2	XP_003802918.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAGILFEDIF DVKDIDPEGK KFDRVSRLHC ESESFKMDLI LDVNIQIYPV DLGDKFRLVI 60 61 ASTLYEDGTL DDGEYNPTDD RPSRADQFEY VMYGKVYRIE GDETSTEAAT RLSAYVSYGG 120 121 LLMRLQGDAN NLHGFEVDSR VYLLMKKLAF 150
Nucleotide CDS Sequence (FASTA)
1 ATGGCCGGCA TCCTCTTTGA GGATATTTTC GATGTGAAAG ATATTGATCC GGAGGGCAAG 60 61 AAGTTTGACC GAGTGTCTCG ATTGCATTGT GAGAGTGAAT CTTTCAAGAT GGATCTCATC 120 121 TTAGATGTAA ACATCCAGAT TTACCCTGTA GACTTAGGTG ACAAGTTTCG GTTGGTCATA 180 181 GCTAGTACCT TGTATGAAGA TGGTACCCTG GATGATGGTG AATACAACCC CACTGATGAC 240 241 AGGCCTTCCA GGGCTGATCA ATTTGAGTAT GTAATGTATG GGAAAGTGTA CCGGATTGAG 300 301 GGAGATGAAA CTTCTACTGA AGCAGCAACA CGCCTGTCTG CCTACGTTTC CTATGGGGGC 360 361 CTGCTCATGA GGCTGCAGGG TGATGCCAAC AACCTGCATG GATTTGAAGT GGATTCCAGA 420 421 GTTTACCTGC TAATGAAGAA ACTGGCCTTC TGA 453

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0539	Nucleus
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0032993	Cellular Component	Protein-DNA complex
GO:0005736	Cellular Component	RNA polymerase I complex
GO:0005665	Cellular Component	RNA polymerase II, core complex
GO:0005666	Cellular Component	RNA polymerase III complex
GO:0003697	Molecular Function	Single-stranded DNA binding
GO:0006366	Biological Process	Transcription by RNA polymerase II
GO:0006383	Biological Process	Transcription by RNA polymerase III

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Loa-2012	Loxodonta africana	100.0	9e-106	305
LLPS-Man-4137	Macaca nemestrina	100.0	9e-106	305
LLPS-Fec-0961	Felis catus	100.0	9e-106	305
LLPS-Mod-0439	Monodelphis domestica	100.0	9e-106	305
LLPS-Pat-1529	Pan troglodytes	100.0	4e-105	305
LLPS-Pap-0665	Pan paniscus	100.0	9e-106	305
LLPS-Urm-1747	Ursus maritimus	100.0	9e-106	305
LLPS-Hos-0617	Homo sapiens	100.0	3e-76	231
LLPS-Rhb-0671	Rhinopithecus bieti	100.0	4e-76	231
LLPS-Fia-1129	Ficedula albicollis	100.0	9e-106	305
LLPS-Orc-0136	Oryctolagus cuniculus	100.0	9e-106	305
LLPS-Pes-1878	Pelodiscus sinensis	100.0	4e-77	231
LLPS-Mam-0175	Macaca mulatta	100.0	4e-76	231
LLPS-Eqc-2801	Equus caballus	100.0	9e-106	305
LLPS-Poa-0262	Pongo abelii	100.0	9e-106	305
LLPS-Ict-3642	Ictidomys tridecemlineatus	100.0	9e-106	305
LLPS-Cas-0117	Carlito syrichta	100.0	9e-106	305
LLPS-Aon-0622	Aotus nancymaae	100.0	9e-106	305
LLPS-Sah-0593	Sarcophilus harrisii	100.0	4e-87	258
LLPS-Sus-3606	Sus scrofa	100.0	9e-106	305
LLPS-Ora-1330	Ornithorhynchus anatinus	100.0	9e-106	305
LLPS-Chs-1429	Chlorocebus sabaeus	100.0	1e-105	306
LLPS-Mea-2463	Mesocricetus auratus	100.0	9e-106	305
LLPS-Maf-2086	Macaca fascicularis	100.0	9e-106	305
LLPS-Mum-0782	Mus musculus	100.0	9e-106	305
LLPS-Caj-1808	Callithrix jacchus	100.0	9e-106	305
LLPS-Fud-0230	Fukomys damarensis	100.0	9e-106	305
LLPS-Gog-3771	Gorilla gorilla	100.0	1e-86	256
LLPS-Bot-2379	Bos taurus	100.0	9e-106	305
LLPS-Dio-0772	Dipodomys ordii	100.0	9e-106	305
LLPS-Tut-0588	Tursiops truncatus	100.0	9e-106	305
LLPS-Aim-0337	Ailuropoda melanoleuca	100.0	9e-106	305
LLPS-Mup-2731	Mustela putorius furo	100.0	9e-106	305
LLPS-Ova-1797	Ovis aries	100.0	9e-106	305
LLPS-Myl-0128	Myotis lucifugus	100.0	9e-106	305
LLPS-Mal-2607	Mandrillus leucophaeus	100.0	9e-106	305
LLPS-Ran-0334	Rattus norvegicus	100.0	9e-106	305
LLPS-Cap-3108	Cavia porcellus	99.33	3e-105	304
LLPS-Anc-1465	Anolis carolinensis	99.33	2e-105	305
LLPS-Ere-0420	Erinaceus europaeus	98.8	3e-53	169
LLPS-Xet-3110	Xenopus tropicalis	98.0	7e-105	303
LLPS-Lac-0033	Latimeria chalumnae	97.33	3e-103	299
LLPS-Pof-2750	Poecilia formosa	97.33	1e-102	297
LLPS-Dar-1267	Danio rerio	97.33	2e-102	297
LLPS-Ten-0185	Tetraodon nigroviridis	97.33	9e-103	298
LLPS-Xim-3590	Xiphophorus maculatus	97.33	1e-102	297
LLPS-Scm-1027	Scophthalmus maximus	96.67	6e-102	296
LLPS-Orn-0284	Oreochromis niloticus	96.67	6e-102	296
LLPS-Tar-1792	Takifugu rubripes	96.67	1e-102	297
LLPS-Anp-1569	Anas platyrhynchos	96.08	5e-65	200
LLPS-Asm-0985	Astyanax mexicanus	96.0	2e-101	294
LLPS-Scf-1975	Scleropages formosus	96.0	2e-101	294
LLPS-Leo-2134	Lepisosteus oculatus	95.54	8e-73	220
LLPS-Orl-0344	Oryzias latipes	95.33	2e-100	291
LLPS-Icp-0578	Ictalurus punctatus	95.33	5e-101	293
LLPS-Gaa-0545	Gasterosteus aculeatus	95.33	4e-101	293
LLPS-Cea-1453	Cercocebus atys	90.7	1e-76	232
LLPS-Paa-1167	Papio anubis	90.7	1e-76	232
LLPS-Nol-0368	Nomascus leucogenys	90.55	4e-77	233
LLPS-Drm-0904	Drosophila melanogaster	78.0	3e-82	246
LLPS-Cii-0585	Ciona intestinalis	75.33	1e-80	241
LLPS-Cis-1064	Ciona savignyi	74.67	2e-80	241
LLPS-Cae-0740	Caenorhabditis elegans	63.33	5e-62	194
LLPS-Gaga-0451	Gallus gallus	59.3	1e-55	179
LLPS-Php-2154	Physcomitrella patens	54.11	6e-49	160
LLPS-Amt-1366	Amborella trichopoda	52.94	5e-29	108
LLPS-Gor-2231	Gossypium raimondii	51.72	8e-43	145
LLPS-Dac-0647	Daucus carota	51.7	2e-41	141
LLPS-Sem-0360	Selaginella moellendorffii	50.68	5e-42	143
LLPS-Mua-2099	Musa acuminata	50.68	1e-43	147
LLPS-Abg-0246	Absidia glauca	50.65	3e-35	125
LLPS-Tru-0692	Triticum urartu	50.48	2e-27	104
LLPS-Nia-0699	Nicotiana attenuata	50.0	1e-40	139
LLPS-Osl-0364	Ostreococcus lucimarinus	50.0	3e-38	133
LLPS-Hea-0671	Helianthus annuus	50.0	1e-41	142
LLPS-Glm-1191	Glycine max	49.66	2e-37	131
LLPS-Thc-0786	Theobroma cacao	49.66	3e-41	140
LLPS-Via-0757	Vigna angularis	49.66	1e-37	132
LLPS-Vir-0502	Vigna radiata	49.66	1e-37	132
LLPS-Orp-0418	Oryza punctata	49.32	3e-41	143
LLPS-Viv-1154	Vitis vinifera	49.32	1e-38	134
LLPS-Orm-0287	Oryza meridionalis	49.32	1e-40	142
LLPS-Orr-0543	Oryza rufipogon	49.32	1e-41	143
LLPS-Org-0396	Oryza glaberrima	49.32	2e-41	143
LLPS-Ori-0765	Oryza indica	49.32	1e-41	143
LLPS-Orb-0450	Oryza barthii	49.32	1e-41	143
LLPS-Sol-1016	Solanum lycopersicum	49.32	1e-40	139
LLPS-Orni-0486	Oryza nivara	49.32	1e-41	143
LLPS-Orgl-0178	Oryza glumaepatula	49.32	1e-41	143
LLPS-Brd-0802	Brachypodium distachyon	49.32	6e-41	140
LLPS-Orbr-0812	Oryza brachyantha	49.31	1e-39	137
LLPS-Phv-0632	Phaseolus vulgaris	48.98	6e-37	130
LLPS-Coc-0468	Corchorus capsularis	48.97	4e-41	140
LLPS-Sot-1380	Solanum tuberosum	48.65	2e-40	139
LLPS-Art-2887	Arabidopsis thaliana	48.28	1e-40	139
LLPS-Brr-0119	Brassica rapa	48.28	7e-40	137
LLPS-Mae-2126	Manihot esculenta	48.28	3e-39	135
LLPS-Bro-0932	Brassica oleracea	48.28	7e-40	137
LLPS-Brn-0656	Brassica napus	48.28	7e-40	137
LLPS-Arl-2511	Arabidopsis lyrata	48.28	2e-40	139
LLPS-Zem-1342	Zea mays	47.97	1e-38	134
LLPS-Lep-0912	Leersia perrieri	47.92	1e-39	137
LLPS-Hov-0390	Hordeum vulgare	47.65	6e-39	137
LLPS-Sob-2032	Sorghum bicolor	47.3	6e-38	133
LLPS-Ors-0819	Oryza sativa	46.98	2e-39	136
LLPS-Tra-1057	Triticum aestivum	46.98	6e-40	137
LLPS-Met-0710	Medicago truncatula	46.31	4e-37	130
LLPS-Pot-1657	Populus trichocarpa	45.52	4e-36	128
LLPS-Sei-0540	Setaria italica	45.27	2e-31	115
LLPS-Prp-0685	Prunus persica	43.62	7e-35	124
LLPS-Cus-0065	Cucumis sativus	42.28	1e-36	129
LLPS-Gas-1005	Galdieria sulphuraria	42.24	9e-35	124
LLPS-Mel-0035	Melampsora laricipopulina	42.18	6e-33	119
LLPS-Nec-0040	Neurospora crassa	41.83	9e-21	88.2
LLPS-Coo-1540	Colletotrichum orbiculare	41.33	8e-24	96.3
LLPS-Cogr-0592	Colletotrichum graminicola	40.67	1e-23	95.5
LLPS-Miv-0035	Microbotryum violaceum	40.41	7e-30	112
LLPS-Map-0859	Magnaporthe poae	40.27	4e-24	97.1
LLPS-Crn-0937	Cryptococcus neoformans	40.24	5e-26	102
LLPS-Pug-0180	Puccinia graminis	40.0	4e-34	122
LLPS-Cog-0228	Colletotrichum gloeosporioides	40.0	1e-22	93.2
LLPS-Trr-0068	Trichoderma reesei	39.86	1e-24	98.6
LLPS-Dos-0124	Dothistroma septosporum	39.69	4e-21	89.0
LLPS-Chr-1482	Chlamydomonas reinhardtii	39.66	7e-20	84.7
LLPS-Cym-0194	Cyanidioschyzon merolae	39.62	4e-26	102
LLPS-Gag-0390	Gaeumannomyces graminis	39.6	1e-23	96.3
LLPS-Blg-0820	Blumeria graminis	39.6	2e-23	95.5
LLPS-Put-0132	Puccinia triticina	39.58	1e-16	77.0
LLPS-Scs-0495	Sclerotinia sclerotiorum	39.33	2e-22	92.4
LLPS-Beb-0358	Beauveria bassiana	39.19	2e-24	97.4
LLPS-Ast-0082	Aspergillus terreus	39.19	9e-23	93.2
LLPS-Trv-0402	Trichoderma virens	39.19	8e-25	99.0
LLPS-Asc-0942	Aspergillus clavatus	38.67	1e-22	93.2
LLPS-Tum-0958	Tuber melanosporum	38.67	6e-20	86.3
LLPS-Scj-1372	Schizosaccharomyces japonicus	38.36	1e-22	92.4
LLPS-Asni-1006	Aspergillus niger	38.1	4e-22	91.7
LLPS-Fus-0088	Fusarium solani	38.0	1e-23	95.5
LLPS-Nef-0644	Neosartorya fischeri	38.0	2e-22	92.4
LLPS-Yal-0070	Yarrowia lipolytica	37.93	1e-13	68.2
LLPS-Spr-0011	Sporisorium reilianum	37.65	1e-22	93.2
LLPS-Asn-1215	Aspergillus nidulans	37.41	2e-23	95.1
LLPS-Asf-0998	Aspergillus flavus	37.41	2e-22	92.4
LLPS-Fuo-0309	Fusarium oxysporum	37.33	2e-22	92.8
LLPS-Asfu-0317	Aspergillus fumigatus	37.33	1e-21	90.5
LLPS-Fuv-0283	Fusarium verticillioides	37.33	2e-22	92.8
LLPS-Usm-0776	Ustilago maydis	37.27	3e-23	95.1
LLPS-Pytr-0335	Pyrenophora triticirepentis	36.91	1e-20	87.4
LLPS-Mao-0561	Magnaporthe oryzae	36.91	3e-22	92.0
LLPS-Pyt-0453	Pyrenophora teres	36.91	1e-20	87.8
LLPS-Asg-0885	Ashbya gossypii	36.67	2e-19	84.3
LLPS-Scp-0267	Schizosaccharomyces pombe	36.55	2e-19	84.0
LLPS-Phn-1060	Phaeosphaeria nodorum	36.49	2e-21	90.1
LLPS-Lem-0320	Leptosphaeria maculans	35.33	1e-20	87.8
LLPS-Sac-0406	Saccharomyces cerevisiae	35.06	3e-20	86.7
LLPS-Zyt-0235	Zymoseptoria tritici	34.72	6e-20	85.9
LLPS-Scc-1041	Schizosaccharomyces cryophilus	34.25	4e-17	77.8
LLPS-Ved-1390	Verticillium dahliae	33.33	5e-19	83.6
LLPS-Kop-0586	Komagataella pastoris	33.33	3e-17	78.6

LLPS-Otg-2921POLR2H

Protein Sequence

Nucleotide Sequence

LLPS-Otg-2921
POLR2H