• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Otg-2748

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: S-formylglutathione hydrolase
Ensembl Gene: ENSOGAG00000010048.2
Ensembl Protein: ENSOGAP00000008976.2
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Serine hydrolase involved in the detoxification of formaldehyde.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MALKQISSNK  CFGGLQKVFE  HDSVELNCKM  KFAVYLPPKA  ESGKCPALYW  LSGLTCTEQN  60
61    FISKSGYHQA  ASEHGLVVIA  PDTSPRGCNI  KGEDDSWDFG  TGAGFYVDAT  EDPWKTNYRM  120
121   YSYITEELPQ  LINANFPVDP  QRMSIFGHSM  GGHGALIYYF  KKMSQFLKSV  SAFAPICNPV  180
181   LCPWGKKAFG  GYLGPDQSKW  KAYDATFLVK  SYQGSQLDIL  IDQGKDDQFL  LDGQLLPDNF  240
241   IAASTEKKIP  VVFRLQEGYD  HSYYFIATFI  ADHIRHHAKY  LNA  283
Nucleotide CDS Sequence (FASTA)
1     ATGGCCTTGA  AACAGATTTC  CAGCAATAAG  TGCTTTGGGG  GATTGCAGAA  AGTTTTTGAA  60
61    CATGACAGTG  TTGAACTAAA  CTGCAAAATG  AAATTTGCTG  TCTACTTACC  ACCAAAGGCA  120
121   GAAAGTGGAA  AGTGCCCTGC  ACTGTATTGG  CTGTCCGGTT  TAACATGCAC  AGAGCAAAAT  180
181   TTTATATCAA  AATCTGGTTA  TCATCAAGCT  GCCTCAGAAC  ACGGCCTTGT  CGTCATTGCT  240
241   CCAGATACCA  GCCCTCGTGG  CTGCAATATT  AAAGGAGAAG  ATGACAGCTG  GGACTTTGGT  300
301   ACCGGAGCTG  GGTTTTACGT  GGATGCCACT  GAAGATCCTT  GGAAAACTAA  CTATAGAATG  360
361   TACTCTTATA  TAACAGAGGA  GCTTCCCCAA  CTCATAAATG  CCAATTTTCC  AGTGGACCCC  420
421   CAAAGGATGT  CAATTTTTGG  CCACTCCATG  GGAGGCCATG  GAGCTCTCAT  TTATTATTTT  480
481   AAAAAAATGA  GTCAATTTCT  GAAGTCTGTA  TCAGCATTTG  CTCCAATTTG  CAACCCAGTG  540
541   CTCTGTCCTT  GGGGCAAAAA  GGCCTTTGGT  GGATATTTAG  GACCAGATCA  AAGTAAATGG  600
601   AAGGCTTATG  ATGCTACCTT  TCTTGTGAAG  TCCTATCAAG  GTTCTCAGCT  GGACATACTA  660
661   ATTGATCAAG  GAAAAGATGA  CCAGTTTCTT  TTAGATGGAC  AGTTACTTCC  TGATAACTTC  720
721   ATAGCTGCGT  CCACAGAAAA  GAAAATCCCT  GTTGTTTTTA  GATTACAAGA  GGGTTATGAT  780
781   CACAGCTACT  ACTTCATTGC  AACCTTTATC  GCTGATCACA  TCAGACATCA  TGCAAAATAC  840
841   CTGAATGCAT  GA  852

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Hydrolase
Reference proteome
Serine esterase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Carboxylic ester hydrolase activity
Molecular Function
S-formylglutathione hydrolase activity
Biological Process
Formaldehyde catabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nol-3861Nomascus leucogenys93.640.0 551
LLPS-Hos-3605Homo sapiens93.290.0 550
LLPS-Caj-3032Callithrix jacchus93.290.0 548
LLPS-Aon-0365Aotus nancymaae93.290.0 549
LLPS-Pap-1142Pan paniscus92.930.0 547
LLPS-Pat-4703Pan troglodytes92.930.0 547
LLPS-Maf-2939Macaca fascicularis92.580.0 546
LLPS-Chs-3378Chlorocebus sabaeus92.580.0 545
LLPS-Mal-3755Mandrillus leucophaeus92.580.0 546
LLPS-Eqc-4726Equus caballus92.470.0 538
LLPS-Man-1017Macaca nemestrina92.230.0 545
LLPS-Cea-0771Cercocebus atys92.230.0 544
LLPS-Paa-0918Papio anubis92.230.0 544
LLPS-Aim-2658Ailuropoda melanoleuca92.230.0 546
LLPS-Urm-3637Ursus maritimus91.870.0 545
LLPS-Caf-4705Canis familiaris91.870.0 544
LLPS-Myl-3437Myotis lucifugus91.870.0 542
LLPS-Rhb-2842Rhinopithecus bieti91.732e-173 487
LLPS-Fec-4277Felis catus91.520.0 543
LLPS-Loa-3077Loxodonta africana91.520.0 541
LLPS-Cas-2883Carlito syrichta91.170.0 538
LLPS-Fud-3777Fukomys damarensis90.810.0 536
LLPS-Sus-3961Sus scrofa90.810.0 539
LLPS-Ict-1358Ictidomys tridecemlineatus90.460.0 537
LLPS-Tut-0102Tursiops truncatus90.460.0 536
LLPS-Dio-4009Dipodomys ordii89.750.0 533
LLPS-Gog-3157Gorilla gorilla89.450.0 508
LLPS-Mum-4052Mus musculus89.40.0 534
LLPS-Mea-1622Mesocricetus auratus89.40.0 531
LLPS-Ova-2300Ovis aries88.690.0 525
LLPS-Mup-0244Mustela putorius furo88.690.0 530
LLPS-Ran-4611Rattus norvegicus88.340.0 526
LLPS-Bot-4750Bos taurus88.340.0 526
LLPS-Cap-2711Cavia porcellus87.990.0 521
LLPS-Orc-1896Oryctolagus cuniculus85.512e-179 503
LLPS-Mam-1039Macaca mulatta84.12e-171 482
LLPS-Ora-0089Ornithorhynchus anatinus84.10.0 507
LLPS-Mod-2841Monodelphis domestica83.750.0 509
LLPS-Sah-3279Sarcophilus harrisii82.811e-179 504
LLPS-Pes-2629Pelodiscus sinensis82.696e-178 500
LLPS-Poa-1613Pongo abelii82.333e-167 471
LLPS-Fia-2671Ficedula albicollis81.12e-157 446
LLPS-Tag-2923Taeniopygia guttata81.055e-176 494
LLPS-Lac-2223Latimeria chalumnae80.212e-173 488
LLPS-Meg-1441Meleagris gallopavo79.866e-174 489
LLPS-Gaga-0207Gallus gallus79.511e-173 488
LLPS-Anc-2948Anolis carolinensis78.84e-170 480
LLPS-Xet-2944Xenopus tropicalis77.891e-168 476
LLPS-Leo-3170Lepisosteus oculatus77.114e-167 472
LLPS-Pof-3409Poecilia formosa77.031e-165 470
LLPS-Anp-2174Anas platyrhynchos76.793e-161 457
LLPS-Dar-0665Danio rerio76.682e-167 473
LLPS-Orl-3512Oryzias latipes76.683e-166 469
LLPS-Scf-0376Scleropages formosus76.63e-165 468
LLPS-Icp-2487Ictalurus punctatus76.335e-168 474
LLPS-Scm-1494Scophthalmus maximus75.627e-165 466
LLPS-Xim-1060Xiphophorus maculatus75.272e-162 461
LLPS-Orn-1002Oreochromis niloticus74.911e-164 466
LLPS-Gaa-2335Gasterosteus aculeatus74.563e-164 465
LLPS-Cii-2345Ciona intestinalis71.433e-44 151
LLPS-Tar-2068Takifugu rubripes70.455e-38 141
LLPS-Asm-2794Astyanax mexicanus68.92e-143 410
LLPS-Ten-3164Tetraodon nigroviridis67.969e-139 400
LLPS-Nia-2125Nicotiana attenuata59.294e-115 340
LLPS-Mua-1993Musa acuminata58.591e-33 124
LLPS-Cis-1208Ciona savignyi58.256e-116 342
LLPS-Sol-0449Solanum lycopersicum58.218e-113 334
LLPS-Met-1482Medicago truncatula58.014e-115 340
LLPS-Sot-1045Solanum tuberosum57.862e-112 333
LLPS-Prp-2210Prunus persica57.81e-112 333
LLPS-Mae-0632Manihot esculenta57.51e-112 333
LLPS-Phv-1380Phaseolus vulgaris57.52e-110 328
LLPS-Hea-1695Helianthus annuus57.58e-113 334
LLPS-Glm-0101Glycine max57.352e-109 325
LLPS-Thc-2200Theobroma cacao57.041e-111 331
LLPS-Gor-2007Gossypium raimondii56.991e-109 326
LLPS-Viv-2295Vitis vinifera56.792e-108 323
LLPS-Php-1171Physcomitrella patens56.792e-119 353
LLPS-Sei-2221Setaria italica56.748e-108 324
LLPS-Arl-1213Arabidopsis lyrata56.583e-109 325
LLPS-Gas-1254Galdieria sulphuraria56.544e-102 307
LLPS-Drm-1817Drosophila melanogaster56.491e-115 343
LLPS-Amt-1749Amborella trichopoda56.471e-107 320
LLPS-Bro-2263Brassica oleracea56.435e-110 327
LLPS-Pot-1453Populus trichocarpa56.185e-105 314
LLPS-Coc-1443Corchorus capsularis56.075e-109 324
LLPS-Art-1096Arabidopsis thaliana55.871e-108 323
LLPS-Brn-2084Brassica napus55.871e-109 326
LLPS-Orbr-1960Oryza brachyantha55.835e-107 319
LLPS-Zem-0141Zea mays55.834e-110 327
LLPS-Ors-1956Oryza sativa55.672e-106 318
LLPS-Orr-1155Oryza rufipogon55.672e-106 318
LLPS-Dac-1695Daucus carota55.365e-108 322
LLPS-Orp-1939Oryza punctata55.322e-104 313
LLPS-Orni-1800Oryza nivara55.327e-106 317
LLPS-Orgl-2239Oryza glumaepatula55.323e-106 318
LLPS-Orb-1407Oryza barthii55.156e-59 192
LLPS-Sob-2341Sorghum bicolor55.121e-109 326
LLPS-Cus-1134Cucumis sativus55.01e-108 323
LLPS-Brd-0287Brachypodium distachyon55.02e-106 318
LLPS-Brr-0351Brassica rapa54.964e-101 304
LLPS-Orm-0348Oryza meridionalis54.961e-104 313
LLPS-Tra-0359Triticum aestivum54.961e-107 321
LLPS-Abg-1173Absidia glauca54.967e-109 324
LLPS-Org-2005Oryza glaberrima54.92e-104 313
LLPS-Via-2231Vigna angularis54.882e-58 191
LLPS-Ast-0768Aspergillus terreus54.863e-100 302
LLPS-Aso-0795Aspergillus oryzae53.989e-100 301
LLPS-Sem-2323Selaginella moellendorffii53.95e-109 325
LLPS-Yal-1403Yarrowia lipolytica53.684e-96 293
LLPS-Asf-1220Aspergillus flavus53.634e-99 299
LLPS-Nef-0592Neosartorya fischeri52.947e-98 296
LLPS-Asfu-1450Aspergillus fumigatus52.942e-97 295
LLPS-Asni-0385Aspergillus niger52.943e-98 297
LLPS-Asc-1503Aspergillus clavatus52.942e-97 295
LLPS-Scs-0951Sclerotinia sclerotiorum52.782e-98 297
LLPS-Usm-0471Ustilago maydis52.114e-97 294
LLPS-Dos-1155Dothistroma septosporum51.935e-97 294
LLPS-Asn-1536Aspergillus nidulans51.99e-96 291
LLPS-Cae-1087Caenorhabditis elegans51.762e-101 305
LLPS-Ori-2041Oryza indica51.481e-90 277
LLPS-Blg-0224Blumeria graminis51.221e-92 282
LLPS-Tum-1100Tuber melanosporum50.872e-89 274
LLPS-Zyt-0692Zymoseptoria tritici50.73e-87 269
LLPS-Pytr-0940Pyrenophora triticirepentis50.529e-94 285
LLPS-Mao-0338Magnaporthe oryzae50.524e-93 284
LLPS-Pyt-0867Pyrenophora teres50.529e-94 285
LLPS-Fuo-1519Fusarium oxysporum50.359e-86 265
LLPS-Fuv-0622Fusarium verticillioides50.359e-86 265
LLPS-Cym-0819Cyanidioschyzon merolae50.172e-92 282
LLPS-Kop-1173Komagataella pastoris49.835e-84 261
LLPS-Fus-1277Fusarium solani49.654e-86 266
LLPS-Chr-0802Chlamydomonas reinhardtii49.486e-97 294
LLPS-Trr-0369Trichoderma reesei49.473e-89 274
LLPS-Miv-1481Microbotryum violaceum49.312e-91 280
LLPS-Trv-1131Trichoderma virens49.284e-86 266
LLPS-Lem-0803Leptosphaeria maculans49.135e-90 277
LLPS-Nec-1436Neurospora crassa48.812e-84 265
LLPS-Spr-0524Sporisorium reilianum48.776e-88 270
LLPS-Lep-2030Leersia perrieri48.577e-101 305
LLPS-Cog-1174Colletotrichum gloeosporioides48.545e-87 268
LLPS-Ved-1084Verticillium dahliae48.248e-85 263
LLPS-Phn-1150Phaeosphaeria nodorum48.088e-89 273
LLPS-Coo-1157Colletotrichum orbiculare47.896e-90 276
LLPS-Tru-1672Triticum urartu47.871e-84 261
LLPS-Gag-1164Gaeumannomyces graminis47.772e-82 257
LLPS-Cogr-1643Colletotrichum graminicola47.76e-86 266
LLPS-Mel-1486Melampsora laricipopulina47.283e-83 259
LLPS-Beb-0308Beauveria bassiana46.831e-83 259
LLPS-Crn-1319Cryptococcus neoformans46.291e-78 246
LLPS-Chc-0841Chondrus crispus46.261e-74 238
LLPS-Map-0767Magnaporthe poae46.055e-79 248
LLPS-Osl-0388Ostreococcus lucimarinus44.332e-68 221
LLPS-Asg-1235Ashbya gossypii43.331e-66 216
LLPS-Sac-0919Saccharomyces cerevisiae38.592e-60 200