• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Otg-2506
POP7

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Ribonuclease P protein subunit p20
Gene Name: POP7
Ensembl Gene: ENSOGAG00000009340.1
Ensembl Protein: ENSOGAP00000008366.1
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION


Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MAENRESRGA  VEAELDPVEY  TLRKRLPHRL  PRRPNDIYVN  MKTDFKAQLA  RCQKLLDGDA  60
61    RGQNACTEIY  IHGLGLAINR  AINIALQLQA  GSFGSLQVAA  NTSTVELVDE  LEPETDTREP  120
121   LTRIRNNSAI  HIRVFRVTPK  140
Nucleotide CDS Sequence (FASTA)
1     ATGGCAGAAA  ACCGAGAGTC  CCGCGGGGCC  GTTGAGGCTG  AGCTGGACCC  GGTGGAGTAC  60
61    ACCCTTAGGA  AACGGCTTCC  CCACCGCCTG  CCCAGGAGGC  CCAATGACAT  TTATGTCAAT  120
121   ATGAAGACTG  ACTTTAAGGC  CCAGTTGGCC  CGTTGCCAGA  AGCTGCTAGA  CGGAGATGCT  180
181   CGAGGTCAGA  ACGCCTGCAC  TGAGATCTAC  ATTCATGGCT  TAGGCCTAGC  CATTAACCGT  240
241   GCCATCAACA  TTGCCCTGCA  GTTACAGGCA  GGCAGCTTTG  GGTCCTTGCA  GGTGGCCGCC  300
301   AATACCTCCA  CGGTGGAGCT  AGTTGATGAG  CTGGAACCAG  AGACTGATAC  ACGGGAGCCC  360
361   TTGACTCGAA  TCCGCAACAA  CTCAGCCATC  CACATCCGAG  TCTTCAGAGT  CACACCCAAG  420
421   TAA  423

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
Hydrolase
Nucleus
Reference proteome
tRNA processing

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Multimeric ribonuclease P complex
Cellular Component
Nucleolus
Cellular Component
Ribonuclease MRP complex
Molecular Function
Nucleic acid binding
Molecular Function
Ribonuclease P activity
Biological Process
TRNA 5'-leader removal

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-2554Fukomys damarensis98.571e-84 251
LLPS-Sus-2165Sus scrofa97.865e-84 249
LLPS-Cap-2527Cavia porcellus97.865e-84 249
LLPS-Eqc-1152Equus caballus97.863e-84 250
LLPS-Bot-2260Bos taurus97.142e-82 254
LLPS-Caj-1738Callithrix jacchus97.148e-84 249
LLPS-Gog-0210Gorilla gorilla97.142e-84 250
LLPS-Aon-0847Aotus nancymaae97.147e-84 249
LLPS-Ict-0406Ictidomys tridecemlineatus97.142e-83 248
LLPS-Poa-2628Pongo abelii97.143e-84 250
LLPS-Caf-1440Canis familiaris97.146e-84 249
LLPS-Orc-2780Oryctolagus cuniculus97.143e-83 247
LLPS-Rhb-0702Rhinopithecus bieti97.143e-84 250
LLPS-Hos-2767Homo sapiens97.142e-84 250
LLPS-Pat-0686Pan troglodytes97.142e-84 250
LLPS-Pap-1182Pan paniscus97.142e-84 250
LLPS-Fec-2523Felis catus97.146e-84 249
LLPS-Paa-1883Papio anubis96.431e-83 248
LLPS-Mal-2582Mandrillus leucophaeus96.431e-83 248
LLPS-Ran-1948Rattus norvegicus96.432e-83 248
LLPS-Tut-1441Tursiops truncatus96.431e-83 248
LLPS-Cea-2664Cercocebus atys96.431e-83 248
LLPS-Maf-4211Macaca fascicularis96.431e-83 248
LLPS-Chs-0784Chlorocebus sabaeus96.431e-83 248
LLPS-Nol-2657Nomascus leucogenys96.431e-83 248
LLPS-Mam-2142Macaca mulatta96.431e-83 248
LLPS-Man-4547Macaca nemestrina96.431e-83 248
LLPS-Urm-2503Ursus maritimus96.433e-83 247
LLPS-Mup-2228Mustela putorius furo95.712e-82 245
LLPS-Myl-2962Myotis lucifugus95.718e-82 244
LLPS-Dio-1258Dipodomys ordii95.03e-81 243
LLPS-Mum-2397Mus musculus95.01e-81 243
LLPS-Cas-1208Carlito syrichta95.01e-80 241
LLPS-Loa-1851Loxodonta africana92.141e-76 230
LLPS-Mea-0576Mesocricetus auratus91.436e-78 234
LLPS-Mod-0892Monodelphis domestica87.321e-69 213
LLPS-Sah-0858Sarcophilus harrisii86.624e-67 206
LLPS-Ora-2465Ornithorhynchus anatinus82.862e-62 194
LLPS-Icp-3269Ictalurus punctatus75.02e-49 161
LLPS-Gaa-2715Gasterosteus aculeatus73.65e-49 160
LLPS-Orl-1097Oryzias latipes73.232e-49 161
LLPS-Pes-0558Pelodiscus sinensis71.962e-43 146
LLPS-Lac-1277Latimeria chalumnae71.922e-57 182
LLPS-Xim-2360Xiphophorus maculatus71.323e-49 161
LLPS-Orn-1945Oreochromis niloticus71.321e-48 160
LLPS-Pof-4103Poecilia formosa71.323e-49 161
LLPS-Dar-1331Danio rerio71.095e-46 153
LLPS-Scf-3394Scleropages formosus70.996e-46 152
LLPS-Leo-3242Lepisosteus oculatus70.452e-44 149
LLPS-Asm-2459Astyanax mexicanus70.374e-49 160
LLPS-Ten-0425Tetraodon nigroviridis68.222e-43 146
LLPS-Scm-1485Scophthalmus maximus67.381e-48 159
LLPS-Tar-0683Takifugu rubripes66.432e-45 151
LLPS-Drm-1562Drosophila melanogaster46.532e-2395.1
LLPS-Cae-1773Caenorhabditis elegans33.018e-1365.9