• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Otg-1746
RACGAP1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Rac GTPase activating protein 1
Gene Name: RACGAP1
Ensembl Gene: ENSOGAG00000004657.2
Ensembl Protein: ENSOGAP00000004162.2
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     DWDSTLVKTF  KLKKREKRRS  NSRQFIDGPP  GPVKKTRSIG  STVDQGNESI  VAKTTVTVPN  60
61    DGGPIEAVST  IETVPYWTRS  RRKTGTLQPW  NSDSTLSSRQ  LEPRTEVDNA  GTPQNTNGGM  120
121   RLHDFVSKTV  IKPESCVPCG  KRIKFGKLSL  KCRDCRVVSH  PECRDRCPLP  CIPTLIGTPV  180
181   KIGEGMLADF  VSQTSPMIPS  IVVHCVNEIE  QRGLTETGLY  RISGCDRTVK  ELKEKFLRAK  240
241   NVPLLSKVDD  IHAICSLLKD  FLRNLKEPLL  TFRLNKAFME  AAEITDEDNS  IAAMYQAVGE  300
301   LPQANRDTLA  FLMIHLQRVA  LSPHTKMDVA  NLAKVFGPTI  VAHAVPNPDP  VTMLQDTKRQ  360
361   PKVVERLLSL  PLEYWSQFMM  VEQENIDPLH  VIENSNAFST  PQTPDIKVSL  LGPVTTPEHQ  420
421   LLKTPSSSSL  SQRVRSTLSK  NTPSRFGSKS  KSATNLGRQG  NFFASPMLK  469
Nucleotide CDS Sequence (FASTA)
1     GATTGGGATT  CTACTTTGGT  GAAGACTTTC  AAACTAAAGA  AGAGAGAAAA  GAGGCGCTCT  60
61    AATAGCCGAC  AGTTCATTGA  TGGTCCCCCT  GGACCTGTAA  AGAAAACGCG  TTCCATTGGC  120
121   TCCACAGTAG  ACCAGGGAAA  TGAATCCATA  GTTGCAAAAA  CTACAGTGAC  TGTTCCTAAT  180
181   GATGGTGGAC  CCATTGAAGC  TGTGTCTACT  ATTGAGACTG  TGCCATATTG  GACTAGGAGC  240
241   CGAAGGAAAA  CAGGTACTTT  GCAGCCTTGG  AACAGTGACT  CCACCCTGAG  CAGCAGGCAG  300
301   CTGGAGCCGA  GAACTGAGGT  GGACAACGCA  GGCACGCCGC  AGAATACAAA  CGGAGGCATG  360
361   CGCCTGCATG  ACTTTGTCTC  TAAGACGGTT  ATTAAACCTG  AATCCTGTGT  TCCATGTGGG  420
421   AAGCGGATAA  AATTTGGCAA  GCTCTCTCTT  AAGTGTCGAG  ACTGTCGTGT  GGTATCTCAT  480
481   CCAGAGTGTC  GGGACCGCTG  TCCCCTTCCC  TGCATTCCCA  CCCTGATAGG  AACACCTGTC  540
541   AAGATTGGAG  AGGGAATGCT  GGCAGATTTT  GTGTCCCAGA  CTTCCCCAAT  GATCCCTTCC  600
601   ATTGTTGTCC  ACTGTGTAAA  TGAGATTGAG  CAAAGAGGGC  TGACTGAGAC  AGGCCTATAT  660
661   AGGATCTCGG  GCTGTGACCG  GACAGTAAAA  GAGCTGAAAG  AGAAATTCCT  CAGAGCAAAA  720
721   AACGTACCTC  TCCTCAGCAA  AGTGGATGAT  ATTCATGCTA  TCTGTAGCCT  CCTGAAAGAC  780
781   TTCCTTCGAA  ACCTTAAAGA  ACCCCTTCTG  ACCTTTCGGC  TAAACAAAGC  CTTTATGGAA  840
841   GCAGCAGAAA  TTACAGATGA  AGACAACAGC  ATAGCTGCCA  TGTACCAAGC  TGTTGGTGAA  900
901   CTTCCCCAGG  CCAACAGGGA  CACATTAGCT  TTTCTAATGA  TTCACTTGCA  GAGAGTGGCT  960
961   CTGAGTCCAC  ATACTAAAAT  GGATGTTGCC  AATTTGGCCA  AAGTCTTTGG  CCCTACAATA  1020
1021  GTTGCCCATG  CTGTGCCCAA  TCCAGACCCT  GTGACAATGT  TACAGGACAC  CAAGCGCCAA  1080
1081  CCCAAGGTGG  TAGAGCGCCT  ACTTTCATTG  CCCCTGGAAT  ATTGGAGTCA  GTTCATGATG  1140
1141  GTGGAGCAAG  AGAACATTGA  CCCTCTGCAT  GTCATTGAAA  ACTCAAATGC  CTTTTCAACA  1200
1201  CCACAGACAC  CTGATATTAA  AGTGAGTTTA  CTGGGGCCTG  TAACCACTCC  TGAGCATCAG  1260
1261  CTTCTCAAGA  CTCCTTCATC  TAGTTCCCTG  TCGCAGAGAG  TCCGCTCCAC  CCTCTCCAAG  1320
1321  AACACTCCCA  GTAGATTTGG  GAGCAAAAGC  AAGTCTGCCA  CAAACCTAGG  ACGACAAGGC  1380
1381  AACTTTTTTG  CTTCTCCAAT  GCTCAAGTGA  1410

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-2673Macaca nemestrina96.590.0 911
LLPS-Poa-1251Pongo abelii96.590.0 909
LLPS-Nol-1115Nomascus leucogenys96.590.0 908
LLPS-Cea-2588Cercocebus atys96.590.0 911
LLPS-Maf-3648Macaca fascicularis96.590.0 911
LLPS-Gog-0655Gorilla gorilla96.590.0 909
LLPS-Paa-0060Papio anubis96.590.0 911
LLPS-Mal-1793Mandrillus leucophaeus96.590.0 911
LLPS-Hos-1104Homo sapiens96.380.0 908
LLPS-Chs-0878Chlorocebus sabaeus96.380.0 909
LLPS-Pat-2260Pan troglodytes96.160.0 907
LLPS-Rhb-3418Rhinopithecus bieti96.160.0 909
LLPS-Pap-1081Pan paniscus95.950.0 905
LLPS-Caj-1142Callithrix jacchus95.950.0 903
LLPS-Ict-2233Ictidomys tridecemlineatus95.740.0 897
LLPS-Urm-1850Ursus maritimus95.310.0 898
LLPS-Orc-0715Oryctolagus cuniculus95.10.0 902
LLPS-Fec-0872Felis catus94.670.0 882
LLPS-Sus-0072Sus scrofa94.240.0 890
LLPS-Eqc-1139Equus caballus94.030.0 889
LLPS-Cas-1587Carlito syrichta94.030.0 892
LLPS-Ova-2765Ovis aries93.60.0 885
LLPS-Mam-0073Macaca mulatta93.339e-2193.6
LLPS-Bot-3598Bos taurus93.180.0 879
LLPS-Loa-1611Loxodonta africana92.320.0 869
LLPS-Myl-1356Myotis lucifugus92.320.0 880
LLPS-Caf-1677Canis familiaris91.930.0 877
LLPS-Cap-2695Cavia porcellus91.90.0 870
LLPS-Fud-2002Fukomys damarensis91.90.0 863
LLPS-Aim-1018Ailuropoda melanoleuca91.720.0 881
LLPS-Ere-0527Erinaceus europaeus91.060.0 855
LLPS-Mod-3134Monodelphis domestica89.840.0 814
LLPS-Mup-1699Mustela putorius furo88.090.0 809
LLPS-Sah-0500Sarcophilus harrisii87.920.0 840
LLPS-Ora-2071Ornithorhynchus anatinus87.420.0 839
LLPS-Aon-0594Aotus nancymaae85.50.0 778
LLPS-Pes-1571Pelodiscus sinensis84.510.0 664
LLPS-Mum-3454Mus musculus83.80.0 787
LLPS-Ran-3487Rattus norvegicus83.370.0 775
LLPS-Tag-2600Taeniopygia guttata80.940.0 741
LLPS-Fia-0895Ficedula albicollis80.60.0 751
LLPS-Anc-2058Anolis carolinensis80.380.0 767
LLPS-Meg-1152Meleagris gallopavo77.880.0 686
LLPS-Lac-2095Latimeria chalumnae76.050.0 732
LLPS-Gaga-1158Gallus gallus75.270.0 709
LLPS-Anp-1430Anas platyrhynchos75.20.0 720
LLPS-Scf-1849Scleropages formosus73.470.0 675
LLPS-Leo-2403Lepisosteus oculatus73.130.0 707
LLPS-Xet-0299Xenopus tropicalis72.010.0 700
LLPS-Icp-0614Ictalurus punctatus70.130.0 657
LLPS-Asm-2411Astyanax mexicanus69.680.0 661
LLPS-Orl-1375Oryzias latipes69.510.0 613
LLPS-Orn-2442Oreochromis niloticus69.050.0 649
LLPS-Scm-1013Scophthalmus maximus68.910.0 601
LLPS-Xim-1585Xiphophorus maculatus68.420.0 627
LLPS-Tar-1590Takifugu rubripes68.270.0 625
LLPS-Ten-1104Tetraodon nigroviridis66.810.0 598
LLPS-Pof-0100Poecilia formosa66.530.0 615
LLPS-Dar-1530Danio rerio64.840.0 638
LLPS-Gaa-3191Gasterosteus aculeatus56.576e-164 484
LLPS-Cis-0408Ciona savignyi44.647e-68 226
LLPS-Mea-4391Mesocricetus auratus43.844e-24 110
LLPS-Dio-2893Dipodomys ordii43.845e-24 109
LLPS-Drm-0193Drosophila melanogaster41.263e-81 270
LLPS-Cii-0710Ciona intestinalis39.64e-22 103
LLPS-Miv-0759Microbotryum violaceum37.021e-24 112
LLPS-Cae-2074Caenorhabditis elegans36.416e-21 100
LLPS-Abg-0738Absidia glauca35.032e-21 102