• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Otg-1548
HSPA4

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Heat shock protein family A (Hsp70) member 4
Gene Name: HSPA4
Ensembl Gene: ENSOGAG00000006501.2
Ensembl Protein: ENSOGAP00000005815.2
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSVVGIDLGF  QSCYVAVARA  GGIETIANEY  SDRCTPACIS  FGPKNRSIGA  AAKSQVISNA  60
61    KNTVQGFKRF  HGRAFSDPFV  EAEKSNLAYD  IVQLPTGLTG  IKVMYMEEER  NFTTEQVTAM  120
121   LLSKLKETAE  SVLKKPVVDC  VVSVPCFYTD  AERRSVMDAT  QIAGLNCLRL  MNETTAVALA  180
181   YGIYKQDLPA  LEEKPRNVVF  VDMGHSAYQV  SVCAFNRGKL  KVLATAFDTT  LGGRKFDEVL  240
241   VNHFCEEFGK  KYKLDIKSKI  RALLRLSQEC  EKLKKLMSAN  ASDLPLSIEC  FMNDIDVSGA  300
301   MNRGKFLEMC  DDLLARVEPP  LRSVLEQARL  KKEDIYAVEL  VGGATRIPAV  KEKISKFFGK  360
361   ELSTTLNADE  AVTRGCALQC  AILSPAFKVR  EFSITDVLPY  PISLRWNSPA  EEGSSDCEVF  420
421   AKNHAAPFSK  VLTFYRKEPF  TLEAYYSFPR  ELPYPDPAIA  QFSVQKVTPQ  SDGSSSKVKV  480
481   KVRVNVHGIF  SVSSASLAEV  HKSEENEEPM  ETDQNAKEEE  KMQVDQEEAH  VEEQQQQTPA  540
541   ENKAESEEME  TSQAGSKDKK  MDQPPQAKKA  KVKTSTVDLP  IENQLLWQID  REMLNLYIEN  600
601   EGKMIMQDKL  EKERNDAKNA  VEEYVYEMRD  KLSGEYEKFV  NRNSFTLKLE  DTENWLYEDG  660
661   EDQPKQVYVD  KLAELKNLGQ  PIKLRFQESE  ERPRLFDELG  KQIQQYMKAI  SSFKNKEDQY  720
721   DHLDAADMMK  VEKSTNEAME  WMNNKLNLQN  KQSLTMDPVV  KSKEIEAKIK  VINAFILIPL  780
781   SFFFFFFKVE  PPKEEQKNAE  QNGPVDGQGD  SPGPQVAEQG  TDTAVPSDSD  KKLPEMDID  839
Nucleotide CDS Sequence (FASTA)
1     ATGTCGGTGG  TGGGCATAGA  CCTGGGCTTC  CAGAGCTGCT  ACGTCGCTGT  GGCACGCGCC  60
61    GGCGGCATCG  AGACTATCGC  CAATGAGTAT  AGCGACCGCT  GCACGCCGGC  TTGCATTTCT  120
121   TTTGGTCCTA  AGAATCGTTC  AATTGGAGCA  GCAGCTAAAA  GCCAGGTAAT  TTCCAATGCA  180
181   AAGAATACAG  TCCAAGGATT  TAAAAGATTC  CATGGCAGAG  CATTCTCTGA  TCCATTTGTG  240
241   GAGGCAGAAA  AATCCAACCT  TGCATATGAT  ATTGTGCAAT  TACCCACTGG  ATTAACAGGT  300
301   ATAAAGGTGA  TGTATATGGA  GGAAGAGAGA  AATTTTACCA  CTGAGCAAGT  GACTGCTATG  360
361   CTTTTGTCCA  AACTGAAGGA  GACAGCAGAA  AGTGTTCTTA  AGAAGCCTGT  TGTTGACTGT  420
421   GTTGTTTCGG  TTCCTTGTTT  CTATACCGAT  GCAGAAAGAC  GATCGGTGAT  GGATGCTACA  480
481   CAGATTGCAG  GTCTCAATTG  CCTGCGATTA  ATGAATGAAA  CTACTGCAGT  TGCTCTTGCA  540
541   TATGGAATCT  ATAAGCAAGA  TCTTCCTGCC  TTAGAAGAGA  AACCAAGAAA  TGTAGTTTTT  600
601   GTAGACATGG  GCCATTCTGC  TTATCAAGTT  TCTGTATGTG  CATTTAATAG  AGGAAAACTG  660
661   AAGGTTCTGG  CCACTGCATT  TGACACAACA  CTGGGAGGCA  GAAAATTTGA  TGAAGTTTTA  720
721   GTAAATCACT  TCTGTGAAGA  ATTTGGGAAG  AAATACAAGC  TAGACATAAA  GTCCAAAATT  780
781   CGTGCATTAT  TACGACTCTC  TCAGGAGTGT  GAGAAACTCA  AGAAATTGAT  GAGTGCAAAT  840
841   GCTTCAGATC  TCCCTCTGAG  CATTGAGTGT  TTTATGAATG  ACATTGATGT  ATCTGGAGCT  900
901   ATGAATAGAG  GCAAATTTCT  GGAAATGTGC  GATGATCTCT  TAGCTAGAGT  GGAGCCACCA  960
961   CTTCGTAGTG  TTTTGGAACA  AGCCAGGTTA  AAGAAAGAAG  ATATTTATGC  AGTGGAGCTA  1020
1021  GTTGGTGGTG  CTACAAGAAT  TCCTGCAGTA  AAAGAGAAGA  TCAGCAAATT  TTTTGGTAAA  1080
1081  GAACTTAGTA  CAACATTAAA  TGCTGATGAA  GCTGTCACTC  GAGGCTGTGC  ATTGCAGTGT  1140
1141  GCAATCTTAT  CGCCTGCTTT  CAAAGTCAGA  GAATTTTCTA  TCACTGATGT  ACTACCCTAT  1200
1201  CCAATCTCTC  TGAGATGGAA  TTCTCCAGCT  GAAGAAGGGT  CAAGTGACTG  TGAAGTCTTT  1260
1261  GCAAAAAATC  ATGCTGCTCC  TTTCTCTAAA  GTTCTCACAT  TTTATAGAAA  GGAACCTTTC  1320
1321  ACTCTTGAGG  CCTATTACAG  CTTTCCTCGG  GAGTTACCCT  ACCCAGATCC  TGCTATAGCC  1380
1381  CAGTTTTCAG  TTCAGAAAGT  CACTCCTCAG  TCTGATGGCT  CCAGTTCAAA  AGTGAAAGTC  1440
1441  AAGGTTCGAG  TAAATGTCCA  TGGCATTTTC  AGTGTGTCTA  GTGCATCCCT  AGCAGAAGTA  1500
1501  CATAAGTCTG  AGGAAAATGA  GGAACCAATG  GAAACAGACC  AGAATGCGAA  GGAGGAAGAG  1560
1561  AAGATGCAGG  TGGACCAGGA  GGAAGCTCAT  GTAGAAGAGC  AACAGCAGCA  GACGCCAGCA  1620
1621  GAAAACAAGG  CAGAGTCTGA  AGAAATGGAG  ACTTCCCAAG  CTGGATCAAA  AGATAAAAAG  1680
1681  ATGGACCAAC  CACCCCAAGC  CAAGAAGGCA  AAAGTGAAGA  CCAGTACTGT  GGACCTGCCA  1740
1741  ATTGAAAATC  AGCTATTATG  GCAGATAGAC  AGAGAGATGC  TCAACTTGTA  CATTGAAAAT  1800
1801  GAGGGTAAGA  TGATCATGCA  GGATAAATTG  GAGAAGGAGC  GGAATGATGC  TAAGAATGCA  1860
1861  GTGGAAGAAT  ATGTGTATGA  AATGAGAGAC  AAGCTTAGTG  GTGAATATGA  GAAGTTTGTG  1920
1921  AATCGTAACA  GTTTTACTTT  GAAACTAGAA  GATACTGAAA  ATTGGTTATA  TGAGGATGGA  1980
1981  GAAGACCAGC  CAAAGCAAGT  TTATGTTGAT  AAATTGGCTG  AATTAAAAAA  TCTAGGTCAA  2040
2041  CCTATTAAGT  TACGGTTCCA  GGAATCTGAA  GAAAGACCAA  GATTATTTGA  TGAACTAGGG  2100
2101  AAACAGATCC  AACAATATAT  GAAAGCAATC  AGTTCTTTCA  AAAACAAGGA  GGACCAGTAT  2160
2161  GACCATTTGG  ATGCTGCTGA  CATGATGAAG  GTAGAAAAAA  GCACAAATGA  AGCAATGGAG  2220
2221  TGGATGAATA  ACAAGCTGAA  TCTGCAGAAC  AAACAGAGTC  TGACTATGGA  TCCAGTTGTC  2280
2281  AAGTCAAAAG  AGATTGAAGC  TAAAATTAAG  GTAATCAATG  CTTTTATATT  AATACCCCTT  2340
2341  TCTTTCTTTT  TTTTTTTTTT  CAAAGTGGAA  CCTCCAAAGG  AGGAGCAAAA  AAATGCTGAG  2400
2401  CAGAATGGAC  CAGTGGATGG  ACAAGGAGAC  AGCCCAGGCC  CACAAGTGGC  TGAGCAGGGT  2460
2461  ACCGACACAG  CTGTCCCTTC  AGATTCAGAC  AAGAAGCTTC  CTGAAATGGA  CATTGATTGA  2520

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-3104Pongo abelii97.10.01060
LLPS-Mup-1119Mustela putorius furo95.760.01464
LLPS-Pap-3495Pan paniscus94.540.01553
LLPS-Pat-1360Pan troglodytes94.540.01553
LLPS-Hos-0654Homo sapiens94.540.01553
LLPS-Gog-1348Gorilla gorilla94.540.01553
LLPS-Sus-2777Sus scrofa94.530.01502
LLPS-Mal-4003Mandrillus leucophaeus94.30.01550
LLPS-Paa-3297Papio anubis94.30.01550
LLPS-Chs-2674Chlorocebus sabaeus94.30.01551
LLPS-Maf-3996Macaca fascicularis94.30.01550
LLPS-Cea-1911Cercocebus atys94.30.01550
LLPS-Mam-3713Macaca mulatta94.180.01548
LLPS-Bot-1870Bos taurus94.180.01554
LLPS-Ova-0616Ovis aries94.070.01535
LLPS-Caj-2638Callithrix jacchus94.060.01546
LLPS-Cas-1361Carlito syrichta93.940.01545
LLPS-Loa-0701Loxodonta africana93.830.01541
LLPS-Fec-3555Felis catus93.820.01542
LLPS-Aon-1478Aotus nancymaae93.820.01544
LLPS-Eqc-3961Equus caballus93.590.01529
LLPS-Caf-0724Canis familiaris93.590.01535
LLPS-Ict-0550Ictidomys tridecemlineatus93.590.01537
LLPS-Nol-2889Nomascus leucogenys92.990.01521
LLPS-Orc-0027Oryctolagus cuniculus92.540.01312
LLPS-Urm-0956Ursus maritimus92.520.01524
LLPS-Mum-3195Mus musculus91.710.01498
LLPS-Aim-3530Ailuropoda melanoleuca91.570.01518
LLPS-Ran-4717Rattus norvegicus91.450.01508
LLPS-Fud-2601Fukomys damarensis91.190.01425
LLPS-Cap-3533Cavia porcellus91.090.01479
LLPS-Rhb-0328Rhinopithecus bieti90.440.01486
LLPS-Man-2495Macaca nemestrina90.110.01459
LLPS-Mea-1740Mesocricetus auratus89.310.01448
LLPS-Ora-3336Ornithorhynchus anatinus87.00.01405
LLPS-Mod-1869Monodelphis domestica84.890.01413
LLPS-Gaga-2748Gallus gallus83.990.01388
LLPS-Tag-0593Taeniopygia guttata83.870.01385
LLPS-Fia-1643Ficedula albicollis83.850.01389
LLPS-Meg-1285Meleagris gallopavo82.750.01312
LLPS-Anc-2323Anolis carolinensis82.240.01373
LLPS-Leo-1083Lepisosteus oculatus74.710.01205
LLPS-Scf-0319Scleropages formosus74.240.01207
LLPS-Asm-4074Astyanax mexicanus71.870.01189
LLPS-Dar-2171Danio rerio71.770.01162
LLPS-Xim-1792Xiphophorus maculatus71.280.01177
LLPS-Icp-2509Ictalurus punctatus71.170.01162
LLPS-Orn-1148Oreochromis niloticus70.860.01164
LLPS-Pof-1481Poecilia formosa70.370.01137
LLPS-Gaa-0531Gasterosteus aculeatus69.590.01142
LLPS-Scm-1521Scophthalmus maximus69.550.01144
LLPS-Tar-3813Takifugu rubripes69.220.01137
LLPS-Orl-1284Oryzias latipes68.550.01136
LLPS-Ten-1516Tetraodon nigroviridis64.310.0 994
LLPS-Tut-0999Tursiops truncatus64.110.01018
LLPS-Lac-1041Latimeria chalumnae62.290.01026
LLPS-Myl-1064Myotis lucifugus62.260.0 993
LLPS-Sah-1120Sarcophilus harrisii62.260.0 937
LLPS-Anp-2841Anas platyrhynchos61.580.01008
LLPS-Pes-3302Pelodiscus sinensis60.540.0 930
LLPS-Xet-1379Xenopus tropicalis58.60.0 975
LLPS-Drm-0698Drosophila melanogaster51.712e-172 527
LLPS-Abg-0173Absidia glauca51.318e-161 494
LLPS-Tum-0121Tuber melanosporum45.610.0 579
LLPS-Scj-0894Schizosaccharomyces japonicus44.875e-178 538
LLPS-Cae-0941Caenorhabditis elegans43.340.0 593
LLPS-Cis-1983Ciona savignyi43.330.0 654
LLPS-Scp-1596Schizosaccharomyces pombe42.634e-169 514
LLPS-Gag-1518Gaeumannomyces graminis42.551e-176 534
LLPS-Map-1221Magnaporthe poae42.534e-174 527
LLPS-Scc-1271Schizosaccharomyces cryophilus42.513e-171 520
LLPS-Zyt-0753Zymoseptoria tritici42.360.0 547
LLPS-Pyt-1013Pyrenophora teres41.963e-176 534
LLPS-Cog-1519Colletotrichum gloeosporioides41.643e-176 535
LLPS-Brn-2089Brassica napus41.620.0 564
LLPS-Hea-1446Helianthus annuus41.530.0 556
LLPS-Glm-2448Glycine max41.510.0 561
LLPS-Brr-1771Brassica rapa41.50.0 561
LLPS-Beb-1239Beauveria bassiana41.431e-173 526
LLPS-Cus-0733Cucumis sativus41.413e-179 545
LLPS-Nia-1589Nicotiana attenuata41.380.0 559
LLPS-Pug-1287Puccinia graminis41.33e-179 543
LLPS-Pytr-0774Pyrenophora triticirepentis41.291e-175 531
LLPS-Miv-0058Microbotryum violaceum41.250.0 552
LLPS-Php-1247Physcomitrella patens41.240.0 568
LLPS-Dos-1447Dothistroma septosporum41.211e-172 524
LLPS-Sem-0493Selaginella moellendorffii41.210.0 547
LLPS-Gor-1791Gossypium raimondii41.190.0 558
LLPS-Phn-1130Phaeosphaeria nodorum41.144e-166 506
LLPS-Mae-1845Manihot esculenta41.130.0 561
LLPS-Bro-0050Brassica oleracea40.910.0 566
LLPS-Phv-0000Phaseolus vulgaris40.94e-180 547
LLPS-Zem-1138Zea mays40.860.0 550
LLPS-Dac-0031Daucus carota40.840.0 550
LLPS-Orp-0550Oryza punctata40.632e-180 548
LLPS-Pot-2601Populus trichocarpa40.68e-177 539
LLPS-Via-1651Vigna angularis40.481e-177 541
LLPS-Mua-0703Musa acuminata40.452e-177 540
LLPS-Coc-1472Corchorus capsularis40.438e-179 544
LLPS-Tra-0309Triticum aestivum40.284e-178 541
LLPS-Usm-1021Ustilago maydis40.240.0 550
LLPS-Met-0940Medicago truncatula40.225e-172 526
LLPS-Orgl-1911Oryza glumaepatula40.184e-179 545
LLPS-Orm-1370Oryza meridionalis40.055e-178 542
LLPS-Sei-1057Setaria italica40.051e-179 546
LLPS-Sol-1932Solanum lycopersicum39.981e-173 547
LLPS-Sob-0001Sorghum bicolor39.975e-179 544
LLPS-Orr-2380Oryza rufipogon39.926e-178 541
LLPS-Org-2232Oryza glaberrima39.928e-178 541
LLPS-Ors-1157Oryza sativa39.926e-178 541
LLPS-Orb-2370Oryza barthii39.928e-178 541
LLPS-Orni-0348Oryza nivara39.928e-178 541
LLPS-Art-0592Arabidopsis thaliana39.90.0 566
LLPS-Brd-0088Brachypodium distachyon39.879e-178 541
LLPS-Sot-1566Solanum tuberosum39.356e-175 535
LLPS-Tru-1415Triticum urartu39.345e-173 528
LLPS-Hov-1876Hordeum vulgare39.242e-175 535
LLPS-Lep-0095Leersia perrieri39.04e-170 521
LLPS-Ori-2433Oryza indica38.842e-163 504
LLPS-Orbr-1222Oryza brachyantha38.252e-167 514