• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Otg-0717
DGKZ

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Diacylglycerol kinase
Gene Name: DGKZ
Ensembl Gene: ENSOGAG00000002350.2
Ensembl Protein: ENSOGAP00000002101.2
Organism: Otolemur garnettii
Taxa ID: 30611
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEPRDGSPEA  RSSDSESASA  SSSGSEHDAS  PELDKAPRRL  SKRRFPGLRL  FGHRKAITKS  60
61    GLPHLAPPPP  APGAPCSESE  RQIRSTVDWS  ESATYGEHIW  FETNVSGDFC  YVGEQYCVAK  120
121   MLQKSVSRRK  CAACKIVVHT  PCIEQLEKIN  FRCKPSFRES  GSRNVREPTF  VRHHWVHRRR  180
181   QDGKCRHCGK  GFQQKFAFHS  KEIVAISCSW  CKQAYHSKVS  CFMLQQIEEP  CSLGVHAAVV  240
241   IPPTWILRAR  RPQNTLKASK  KKKRASFKRK  SSKKGPEEGR  WRPFIIRPTP  SPLMKPLLVF  300
301   VNPKSGGNQG  AKIIQSFLWY  LNPRQVFDLS  QGGPKEALEM  YRKVHNLRIL  ACGGDGTVGW  360
361   ILSTLDQLRL  KPPPPVAILP  LGTGNDLART  LNWGGGYTDE  PVSKILSHVE  EGNVVQLDRW  420
421   DLHAEPNPDA  GPEERDEGAT  DLPLDVFNNY  FSLGFDAHVT  LEFHESREAN  PEKFNSRFRN  480
481   KMFYAGTAFS  DFLMGSSKDL  AKHIRVVCDG  TDLTPKIQDL  KPQCIVFLNI  PRYCAGTMPW  540
541   GHPGEHHDFE  PQRHDDGYLE  VIGFTMTSLA  ALQVGGHGER  LTQCREVVLT  TSKAIPVQVD  600
601   GEPCKLTASR  IRIALRNQAT  MVQKAKRRSA  APLHSDQQPV  PEQLRIQVSR  VSMHDYEALH  660
661   YDKEQLKEAS  VPLGTVVVPG  DSDLELCRAL  IERLQQEPDG  AEAKSLTCQK  LSPKWCFLDA  720
721   TTASRFYRID  RAQEHLNYVT  EIAQDEIYIL  DPELLGASAR  PDLPTPTSPL  PTSPCSPTPR  780
781   SLQGDAAPPQ  GEELIEAAKR  NDFCKLQELH  RAGGDIMHRD  ERGRTLLHHA  VGTGSKEVVR  840
841   YLLDHAPPEI  LDAVEENGET  CLHQAAALGQ  RTICHYIVEA  GASLMKTDQQ  GDTPRQRAEK  900
901   AQDTELAAYL  ENRQHYQMIQ  REDQETAV  928
Nucleotide CDS Sequence (FASTA)
1     ATGGAGCCGC  GGGACGGTAG  CCCCGAGGCC  CGGAGCAGCG  ACTCCGAGTC  GGCCTCCGCC  60
61    TCGTCCAGCG  GCTCCGAGCA  CGACGCCAGT  CCGGAACTGG  ACAAGGCGCC  GCGGCGCCTG  120
121   AGCAAGCGGC  GCTTCCCAGG  GCTGAGGCTC  TTCGGGCACA  GGAAAGCCAT  CACCAAGTCT  180
181   GGCCTCCCAC  ACCTGGCACC  CCCACCCCCT  GCCCCGGGGG  CCCCGTGCAG  CGAGTCAGAG  240
241   CGGCAGATCC  GGAGCACCGT  GGACTGGAGC  GAGTCAGCGA  CGTATGGGGA  GCACATCTGG  300
301   TTCGAGACCA  ATGTGTCTGG  GGACTTCTGC  TATGTGGGGG  AGCAGTACTG  TGTAGCCAAG  360
361   ATGCTGCAGA  AATCAGTGTC  CCGGAGAAAG  TGCGCAGCCT  GCAAGATCGT  GGTACACACA  420
421   CCCTGCATCG  AACAGCTGGA  GAAGATAAAT  TTCCGCTGTA  AGCCATCCTT  CCGGGAATCA  480
481   GGCTCCAGGA  ACGTTCGCGA  ACCAACGTTT  GTACGGCACC  ACTGGGTCCA  CAGGCGACGC  540
541   CAGGACGGCA  AGTGTCGGCA  CTGTGGGAAG  GGCTTCCAAC  AGAAGTTCGC  CTTCCACAGC  600
601   AAGGAGATCG  TGGCCATCAG  CTGTTCCTGG  TGCAAGCAAG  CATACCACAG  CAAGGTGTCC  660
661   TGCTTCATGC  TGCAGCAGAT  CGAGGAACCC  TGCTCTCTAG  GTGTCCATGC  AGCTGTGGTC  720
721   ATCCCACCCA  CCTGGATCCT  CCGTGCCCGC  AGGCCCCAGA  ATACCCTCAA  GGCAAGCAAG  780
781   AAGAAGAAGC  GAGCATCCTT  CAAGAGAAAA  TCTAGCAAGA  AAGGGCCTGA  GGAGGGCCGC  840
841   TGGAGACCCT  TCATCATTAG  GCCTACCCCC  TCTCCCCTCA  TGAAGCCCCT  GCTGGTGTTT  900
901   GTGAACCCCA  AGAGTGGGGG  CAACCAGGGC  GCTAAGATCA  TCCAGTCCTT  CCTCTGGTAT  960
961   CTCAATCCCC  GACAAGTCTT  TGACCTGAGC  CAGGGAGGGC  CCAAAGAGGC  ACTGGAGATG  1020
1021  TACCGCAAAG  TGCACAACCT  GCGGATCCTG  GCGTGTGGAG  GTGACGGCAC  GGTCGGCTGG  1080
1081  ATTCTCTCTA  CCTTGGACCA  GCTGCGCTTA  AAACCGCCAC  CCCCTGTCGC  CATCCTGCCC  1140
1141  CTGGGTACTG  GCAATGACTT  GGCCCGCACC  CTCAACTGGG  GTGGGGGCTA  CACAGATGAG  1200
1201  CCTGTGTCGA  AGATCCTCTC  TCATGTAGAG  GAGGGGAATG  TAGTACAGCT  GGACCGCTGG  1260
1261  GACCTCCATG  CTGAGCCTAA  CCCAGACGCA  GGGCCTGAGG  AGCGAGACGA  GGGTGCCACT  1320
1321  GACCTGCCCC  TGGACGTCTT  CAACAACTAC  TTCAGCCTGG  GCTTTGATGC  CCATGTCACT  1380
1381  CTGGAGTTTC  ATGAGTCTCG  AGAGGCCAAT  CCAGAGAAAT  TCAACAGCCG  CTTTCGGAAT  1440
1441  AAGATGTTCT  ATGCCGGGAC  AGCCTTCTCT  GACTTCCTGA  TGGGCAGCTC  CAAGGACTTG  1500
1501  GCCAAGCACA  TCCGAGTGGT  GTGTGACGGA  ACTGACCTGA  CCCCCAAGAT  TCAGGACCTG  1560
1561  AAACCCCAGT  GCATTGTTTT  CCTGAACATC  CCCAGGTACT  GTGCAGGCAC  CATGCCCTGG  1620
1621  GGCCACCCTG  GGGAGCATCA  TGACTTTGAG  CCCCAGCGGC  ATGATGATGG  CTACCTCGAG  1680
1681  GTCATTGGCT  TCACCATGAC  ATCCTTGGCT  GCACTGCAGG  TGGGTGGCCA  TGGCGAGCGA  1740
1741  CTGACTCAGT  GTCGTGAGGT  AGTGCTCACC  ACGTCCAAGG  CCATCCCAGT  GCAGGTAGAT  1800
1801  GGTGAGCCCT  GCAAGCTCAC  AGCCTCACGC  ATTCGCATCG  CCCTGCGCAA  CCAGGCCACC  1860
1861  ATGGTGCAGA  AAGCCAAGCG  GCGAAGTGCT  GCCCCACTGC  ACAGCGACCA  GCAGCCTGTT  1920
1921  CCGGAGCAGT  TGCGGATCCA  GGTGAGCAGA  GTCAGCATGC  ACGACTACGA  GGCGCTGCAT  1980
1981  TATGATAAGG  AGCAGCTCAA  GGAGGCTTCT  GTGCCCCTAG  GCACCGTGGT  GGTCCCTGGA  2040
2041  GACAGTGACC  TGGAGCTCTG  CCGTGCTCTC  ATCGAGAGGC  TCCAGCAGGA  ACCTGATGGT  2100
2101  GCTGAAGCCA  AGTCTCTGAC  GTGCCAGAAA  CTGTCCCCTA  AGTGGTGCTT  TCTGGACGCC  2160
2161  ACCACTGCTA  GCCGCTTCTA  TAGGATCGAC  CGAGCCCAGG  AACACCTCAA  CTATGTGACT  2220
2221  GAGATTGCAC  AAGACGAGAT  CTATATCCTG  GACCCGGAGC  TGCTGGGGGC  ATCAGCCCGG  2280
2281  CCTGACCTTC  CAACCCCTAC  TTCCCCTCTC  CCCACCTCAC  CCTGCTCTCC  CACGCCCCGG  2340
2341  TCACTGCAAG  GGGATGCCGC  CCCCCCTCAA  GGTGAAGAGC  TGATTGAGGC  TGCCAAGAGG  2400
2401  AACGACTTTT  GTAAGCTCCA  GGAGCTGCAC  CGAGCTGGGG  GTGACATCAT  GCACCGGGAT  2460
2461  GAGCGTGGCC  GCACACTCCT  CCACCATGCA  GTCGGCACCG  GCAGCAAGGA  GGTGGTCCGC  2520
2521  TACCTGCTGG  ACCATGCTCC  TCCAGAGATC  CTTGATGCTG  TGGAAGAAAA  TGGGGAGACT  2580
2581  TGTCTGCACC  AGGCCGCAGC  CCTGGGCCAG  CGCACCATCT  GCCACTACAT  CGTGGAGGCT  2640
2641  GGGGCCTCAC  TCATGAAGAC  AGACCAGCAG  GGCGACACTC  CCCGGCAGCG  GGCAGAGAAG  2700
2701  GCTCAGGACA  CAGAGCTGGC  TGCCTACCTG  GAGAACCGGC  AGCACTACCA  GATGATCCAG  2760
2761  CGGGAGGACC  AAGAGACTGC  TGTGTAG  2787

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-2947Macaca nemestrina97.940.01657
LLPS-Chs-3985Chlorocebus sabaeus97.880.01699
LLPS-Hos-4697Homo sapiens97.830.01653
LLPS-Pap-4591Pan paniscus97.830.01654
LLPS-Pat-1239Pan troglodytes97.710.01652
LLPS-Maf-2931Macaca fascicularis97.710.01652
LLPS-Cea-4363Cercocebus atys97.710.01654
LLPS-Gog-4323Gorilla gorilla97.60.01647
LLPS-Nol-3925Nomascus leucogenys97.490.01570
LLPS-Eqc-1681Equus caballus97.370.01645
LLPS-Ict-1253Ictidomys tridecemlineatus97.370.01652
LLPS-Fec-3943Felis catus97.260.01641
LLPS-Caj-4424Callithrix jacchus97.260.01642
LLPS-Dio-3505Dipodomys ordii97.170.01333
LLPS-Cas-3385Carlito syrichta97.130.01562
LLPS-Mup-1544Mustela putorius furo96.920.01644
LLPS-Sus-2092Sus scrofa96.910.01631
LLPS-Mal-2787Mandrillus leucophaeus96.690.01633
LLPS-Paa-3714Papio anubis96.570.01624
LLPS-Cap-3410Cavia porcellus96.460.01634
LLPS-Caf-3465Canis familiaris96.00.01617
LLPS-Ran-4804Rattus norvegicus95.980.01664
LLPS-Aim-3870Ailuropoda melanoleuca95.680.01615
LLPS-Loa-3406Loxodonta africana95.220.01599
LLPS-Myl-4192Myotis lucifugus94.950.01617
LLPS-Mea-1761Mesocricetus auratus94.850.01635
LLPS-Mum-2900Mus musculus94.740.01606
LLPS-Aon-2510Aotus nancymaae94.70.01636
LLPS-Bot-4802Bos taurus92.810.01548
LLPS-Rhb-4801Rhinopithecus bieti92.040.01521
LLPS-Mam-3413Macaca mulatta90.530.01471
LLPS-Urm-3988Ursus maritimus86.740.01430
LLPS-Dar-2412Danio rerio82.910.01209
LLPS-Scf-3217Scleropages formosus81.730.01188
LLPS-Pes-2872Pelodiscus sinensis81.620.01441
LLPS-Anp-0511Anas platyrhynchos80.070.01436
LLPS-Fud-3819Fukomys damarensis80.020.01313
LLPS-Anc-3772Anolis carolinensis79.930.01362
LLPS-Meg-2174Meleagris gallopavo79.910.01435
LLPS-Gaga-2735Gallus gallus79.60.01416
LLPS-Tag-1972Taeniopygia guttata79.120.01445
LLPS-Pof-2403Poecilia formosa78.780.01109
LLPS-Scm-2421Scophthalmus maximus78.770.01151
LLPS-Xim-1389Xiphophorus maculatus78.410.01113
LLPS-Fia-2474Ficedula albicollis77.010.01414
LLPS-Leo-2160Lepisosteus oculatus76.610.01371
LLPS-Icp-2402Ictalurus punctatus73.720.01299
LLPS-Xet-2686Xenopus tropicalis73.170.01274
LLPS-Orl-3015Oryzias latipes72.20.01094
LLPS-Gaa-3185Gasterosteus aculeatus72.170.01277
LLPS-Ten-3438Tetraodon nigroviridis71.110.01232
LLPS-Orn-3708Oreochromis niloticus70.360.01239
LLPS-Tar-0366Takifugu rubripes69.880.01291
LLPS-Lac-1436Latimeria chalumnae68.510.01214
LLPS-Asm-1131Astyanax mexicanus62.50.01145
LLPS-Cii-1401Ciona intestinalis47.690.0 763
LLPS-Sah-3416Sarcophilus harrisii43.172e-62 232
LLPS-Cae-0539Caenorhabditis elegans42.58e-67 246
LLPS-Mod-2699Monodelphis domestica41.871e-62 233
LLPS-Ora-3057Ornithorhynchus anatinus40.413e-64 236
LLPS-Tut-0051Tursiops truncatus40.115e-64 237
LLPS-Poa-4116Pongo abelii37.991e-43 174
LLPS-Ova-3639Ovis aries37.36e-0860.8
LLPS-Orc-3306Oryctolagus cuniculus36.841e-0656.6
LLPS-Ved-0041Verticillium dahliae36.561e-0655.1
LLPS-Chr-0644Chlamydomonas reinhardtii35.963e-0861.2
LLPS-Scp-1390Schizosaccharomyces pombe34.885e-0652.8
LLPS-Sob-0937Sorghum bicolor34.786e-0755.1
LLPS-Sei-1125Setaria italica33.914e-0652.8
LLPS-Scc-1352Schizosaccharomyces cryophilus33.76e-0754.3
LLPS-Map-1065Magnaporthe poae33.675e-0755.8
LLPS-Tra-2619Triticum aestivum32.611e-0655.1
LLPS-Brr-2712Brassica rapa32.176e-0857.4
LLPS-Bro-2549Brassica oleracea32.177e-0857.4
LLPS-Tru-1145Triticum urartu32.173e-0652.4
LLPS-Brn-0663Brassica napus32.176e-0857.4
LLPS-Orb-2125Oryza barthii32.041e-0654.7
LLPS-Pot-1979Populus trichocarpa31.94e-0858.2
LLPS-Mua-2146Musa acuminata31.863e-0756.6
LLPS-Orp-0716Oryza punctata31.781e-0654.7
LLPS-Zem-0371Zea mays31.786e-0651.2
LLPS-Vir-0603Vigna radiata31.784e-0652.0
LLPS-Yal-0797Yarrowia lipolytica31.586e-0652.4
LLPS-Art-2912Arabidopsis thaliana31.34e-0858.2
LLPS-Arl-2551Arabidopsis lyrata31.37e-0857.4
LLPS-Mae-0007Manihot esculenta31.039e-0650.8
LLPS-Orm-1280Oryza meridionalis30.972e-0653.1
LLPS-Cis-0795Ciona savignyi29.376e-0755.8
LLPS-Glm-2979Glycine max29.235e-0755.8
LLPS-Phv-1982Phaseolus vulgaris28.875e-0858.9
LLPS-Dac-1740Daucus carota28.461e-0756.6
LLPS-Php-2216Physcomitrella patens27.731e-0653.9