• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orn-1918

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Frizzled class receptor 8a
Ensembl Gene: ENSONIG00000020641.1
Ensembl Protein: ENSONIP00000025946.1
Organism: Oreochromis niloticus
Taxa ID: 8128
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSONIT00000025967.1ENSONIP00000025946.1
UniProtI3KXV0, I3KXV0_ORENI
GeneBankAERX01023828

▼ SEQUENCE

Protein Sequence (FASTA)
1     RRLRQSRKRG  TRRAGEMDLF  GIYLLLSLVL  FPRSSCTTAK  EITCQEIAVP  LCKGIGYNYT  60
61    YMPNQFNHDT  QDEAGLEVHQ  FWPLVEIQCS  PDLKFFLCSM  YTPICLEDYK  KPLPPCRSVC  120
121   ERARAGCAPL  MRQYGFPWPD  RMRCDLLPVQ  GNPDTLCMDY  NRTDSTTASP  VLSKPTNHPG  180
181   KGYNPPKNKP  GRPGTPGKYK  PPAAPCEPGC  TCLEPMVPVN  TERHPLYNRV  KTGQITNCAM  240
241   PCHNPYFTHD  ERAFTAFWIG  LWSVLCFVST  FATVATFLID  MERFKYPERP  IIFLSACYMF  300
301   VSVGYIVRLI  AGHEKVACNR  EFDVEHIHYE  TTGPALCTVV  FLLIYFFGMA  SSIWWVILSL  360
361   TWFLAAGMKW  GNEAIASYSQ  YFHLAAWLIP  SMKSIAVLAL  SSVDGDSVAG  ICYVGNQNLD  420
421   NLRGFVLAPL  VIYLFIGTMF  LLAGFVSLFR  IRSVIKQGGT  KTDKLEKLMI  RIGIFTVLYT  480
481   VPATIIVACY  FYEQHNRQSW  EITHNCFNCL  LERDRRTPDY  AVFMLKYFMC  LLVGITSGVW  540
541   IWSGKTLDSW  RTFCTRCCWG  SKGTSGSMYS  DVSTGLTWRS  GTASSVSCPK  QMPLSQV  597
Nucleotide CDS Sequence (FASTA)
1     CGCCGTTTGC  GCCAGAGCAG  AAAGAGAGGG  ACGCGACGCG  CCGGAGAGAT  GGACCTGTTT  60
61    GGGATTTATC  TGCTCCTCTC  GCTCGTTCTC  TTTCCGCGAT  CCAGCTGCAC  CACAGCCAAG  120
121   GAGATCACCT  GCCAGGAGAT  AGCCGTGCCT  CTGTGCAAGG  GAATCGGCTA  CAACTACACG  180
181   TACATGCCCA  ACCAGTTTAA  CCACGACACG  CAGGACGAGG  CGGGACTGGA  GGTGCACCAG  240
241   TTCTGGCCTC  TGGTTGAGAT  CCAGTGCTCG  CCGGACCTGA  AGTTCTTCCT  CTGCAGCATG  300
301   TACACGCCGA  TCTGCCTGGA  GGACTACAAA  AAACCTCTCC  CCCCGTGCCG  GAGCGTGTGT  360
361   GAGAGAGCTC  GGGCCGGCTG  TGCGCCTCTC  ATGAGGCAGT  ACGGATTTCC  CTGGCCGGAC  420
421   AGGATGAGGT  GCGACCTGCT  GCCGGTGCAG  GGCAACCCAG  ACACGCTGTG  CATGGACTAC  480
481   AACAGAACCG  ATTCAACTAC  AGCGTCCCCG  GTGCTCTCCA  AACCCACCAA  CCACCCAGGT  540
541   AAGGGTTACA  ATCCGCCGAA  AAATAAGCCC  GGCAGACCCG  GCACGCCGGG  GAAATACAAG  600
601   CCGCCCGCCG  CTCCGTGCGA  GCCGGGATGC  ACATGTTTGG  AGCCCATGGT  GCCGGTGAAC  660
661   ACGGAACGGC  ACCCGCTGTA  CAACCGGGTC  AAGACGGGGC  AGATCACCAA  CTGCGCCATG  720
721   CCGTGCCACA  ATCCCTATTT  TACGCACGAC  GAAAGAGCGT  TCACCGCTTT  TTGGATCGGA  780
781   CTTTGGTCAG  TGCTGTGCTT  TGTGTCCACC  TTCGCCACCG  TGGCTACTTT  CCTCATCGAC  840
841   ATGGAGCGCT  TCAAGTACCC  GGAGAGACCC  ATCATCTTCC  TCTCGGCATG  TTACATGTTC  900
901   GTGTCGGTCG  GCTACATCGT  CAGGCTGATC  GCCGGGCACG  AGAAAGTGGC  GTGCAACCGG  960
961   GAGTTCGACG  TGGAGCACAT  CCACTACGAG  ACGACCGGCC  CCGCGCTCTG  CACCGTGGTC  1020
1021  TTCCTCCTTA  TTTACTTTTT  CGGCATGGCC  AGCTCCATTT  GGTGGGTCAT  CCTCTCCCTG  1080
1081  ACCTGGTTCC  TGGCGGCCGG  GATGAAGTGG  GGCAACGAGG  CGATCGCCAG  CTACTCTCAG  1140
1141  TACTTCCACC  TGGCCGCTTG  GCTCATCCCC  AGCATGAAGT  CCATCGCGGT  CCTGGCGTTG  1200
1201  AGCTCCGTGG  ATGGAGACTC  GGTGGCAGGC  ATCTGTTACG  TGGGGAACCA  GAACCTGGAC  1260
1261  AACCTGCGGG  GATTCGTCCT  CGCGCCTTTG  GTGATTTATT  TATTCATAGG  GACGATGTTC  1320
1321  CTGCTGGCTG  GATTTGTGTC  GCTGTTCAGG  ATCCGCAGCG  TCATCAAGCA  GGGCGGCACC  1380
1381  AAAACTGACA  AACTCGAGAA  GCTGATGATC  AGAATAGGCA  TCTTCACGGT  GCTCTACACG  1440
1441  GTGCCCGCCA  CTATCATAGT  GGCCTGTTAC  TTTTACGAGC  AGCACAACAG  ACAGAGCTGG  1500
1501  GAGATCACGC  ACAACTGCTT  TAACTGTTTA  TTAGAGCGGG  ACCGCAGGAC  TCCGGACTAT  1560
1561  GCCGTTTTTA  TGCTGAAATA  CTTTATGTGC  CTTCTAGTGG  GCATTACGTC  CGGGGTGTGG  1620
1621  ATCTGGTCTG  GAAAAACTTT  GGACTCTTGG  AGAACTTTCT  GCACCAGGTG  CTGCTGGGGC  1680
1681  AGCAAAGGCA  CCAGCGGCTC  CATGTACAGC  GACGTGAGCA  CCGGACTGAC  GTGGAGGTCG  1740
1741  GGCACAGCCA  GCTCTGTGTC  TTGCCCCAAG  CAGATGCCAC  TGTCCCAGGT  TTGA  1794

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scm-3061Scophthalmus maximus96.560.01123
LLPS-Tar-0413Takifugu rubripes96.150.01117
LLPS-Xim-2313Xiphophorus maculatus95.350.01090
LLPS-Pof-3914Poecilia formosa94.40.01110
LLPS-Bot-3669Bos taurus93.082e-79 271
LLPS-Paa-3917Papio anubis93.082e-79 271
LLPS-Sus-1863Sus scrofa93.081e-79 271
LLPS-Mam-3072Macaca mulatta93.082e-79 271
LLPS-Hos-2823Homo sapiens93.082e-79 271
LLPS-Orl-0709Oryzias latipes92.870.01071
LLPS-Dar-1590Danio rerio90.890.01071
LLPS-Fud-1386Fukomys damarensis89.891e-50 185
LLPS-Leo-1284Lepisosteus oculatus89.610.01058
LLPS-Lac-3754Latimeria chalumnae87.460.01043
LLPS-Ten-2780Tetraodon nigroviridis84.470.0 995
LLPS-Asm-3676Astyanax mexicanus82.910.0 959
LLPS-Xet-2191Xenopus tropicalis81.490.0 954
LLPS-Maf-3733Macaca fascicularis80.780.0 872
LLPS-Fia-1030Ficedula albicollis75.860.0 872
LLPS-Ran-3519Rattus norvegicus71.30.0 900
LLPS-Mea-0894Mesocricetus auratus71.210.0 884
LLPS-Mum-4523Mus musculus71.190.0 902
LLPS-Mod-3477Monodelphis domestica70.160.0 893
LLPS-Man-3079Macaca nemestrina60.030.0 640
LLPS-Anc-0599Anolis carolinensis52.170.0 542
LLPS-Mup-4292Mustela putorius furo51.70.0 531
LLPS-Scf-0866Scleropages formosus51.642e-178 522
LLPS-Caj-3662Callithrix jacchus51.610.0 533
LLPS-Caf-4678Canis familiaris51.610.0 535
LLPS-Tag-1812Taeniopygia guttata51.480.0 543
LLPS-Aon-4589Aotus nancymaae51.420.0 533
LLPS-Cea-2466Cercocebus atys51.420.0 531
LLPS-Chs-0268Chlorocebus sabaeus51.420.0 533
LLPS-Gog-4196Gorilla gorilla51.420.0 532
LLPS-Eqc-4510Equus caballus51.420.0 531
LLPS-Poa-0448Pongo abelii51.420.0 532
LLPS-Ict-0522Ictidomys tridecemlineatus51.420.0 532
LLPS-Pat-1317Pan troglodytes51.420.0 532
LLPS-Loa-2618Loxodonta africana50.761e-180 528
LLPS-Otg-4310Otolemur garnettii50.650.0 535
LLPS-Cap-4142Cavia porcellus49.819e-178 522
LLPS-Nol-3646Nomascus leucogenys49.722e-168 498
LLPS-Gaa-3612Gasterosteus aculeatus44.123e-26 114
LLPS-Ere-0439Erinaceus europaeus43.753e-1373.9
LLPS-Dio-2743Dipodomys ordii40.353e-22 101
LLPS-Tut-0987Tursiops truncatus40.354e-22 101
LLPS-Ova-3313Ovis aries40.354e-22 101
LLPS-Myl-0016Myotis lucifugus40.356e-22 100
LLPS-Mal-4085Mandrillus leucophaeus40.353e-22 102
LLPS-Fec-2432Felis catus40.359e-2197.4
LLPS-Pap-3412Pan paniscus40.354e-22 101
LLPS-Urm-3160Ursus maritimus40.354e-22 101
LLPS-Rhb-3554Rhinopithecus bieti40.353e-22 102
LLPS-Ora-2471Ornithorhynchus anatinus40.02e-22 102
LLPS-Pes-0108Pelodiscus sinensis40.01e-22 100
LLPS-Orc-2503Oryctolagus cuniculus38.583e-22 102
LLPS-Gaga-3401Gallus gallus37.83e-23 104
LLPS-Meg-2774Meleagris gallopavo37.83e-23 105
LLPS-Cii-1411Ciona intestinalis36.512e-2199.8
LLPS-Cis-1781Ciona savignyi35.26e-2095.1