LLPS-Orn-1545
PDE3A
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Phosphodiesterase |
| Gene Name: | PDE3A |
| Ensembl Gene: | ENSONIG00000008508.1 |
| Ensembl Protein: | ENSONIP00000010697.1 |
| Organism: | Oreochromis niloticus |
| Taxa ID: | 8128 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Receptor cluster | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSONIT00000010706.1 | ENSONIP00000010697.1 |
| Ensembl | ENSONIT00000010705.1 | ENSONIP00000010696.1 |
| UniProt | I3JPA3, I3JPA3_ORENI | |
| GeneBank | AERX01010918, AERX01010917 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 WVRLMFTKIW SSQRLRSAVC VGSLSFFLAL LVKCADWKAD ASSSADSRLS HSSSPLHFVS 60 61 GCAAELLQTC WSVVSPLFTL VCAFFWVGVY LIRCGVLIQT AISLLTLCHL GEVAAWSLLD 120 121 GTDEQLFSFT TAAVVVLLCV ATGALMVVRL NQGISVIVFI SVVRTISLFS LHKVRATWRP 180 181 YVAYLVGVLG ILLARYAEKL LPNQGRHKEG CTPVTEAREE IPVFKRRRRS SSVIASDMAH 240 241 SQSNSKSHRR TSLPCIQRDQ MLPRSDWDHK RGSRGSQSSG TTVMVDIAVM GEAHGLITDL 300 301 LADPSLPPNT CTSLRAVSNM LTTQLTFQPL HRPRPAPLHN PSDVYTCSDS EEVPEKGEKT 360 361 SIHKRLRRSL HPGLLRRISS TWTTTTSATG LPTIEPGPVR RDRSASIKPY HEALTCRYLS 420 421 HTCFTPQILV TLEFQRSFSL KFFSCACSPH VKNKEQRRPG SQVPYSYAQP SSMPQQAATC 480 481 QHVISQGVIR TLGFFFSPSL VFPSCQPSMT YTGRGQPELT ARLKPYKKKS SKSCGRPYIR 540 541 LNHGEGSLDK GDRIPRSERT KPAEDQVVVS SDYDSTHEAN HSDSSDVAHT EDDAEEGKNS 600 601 QNVILHALIP PELLLTQDKP ILAPEPLIME GLEPLMSQLN NWNFPIFTLI EKTNGKCGRI 660 661 LSQVSYRLFE DTGLFETFKI PVKEFMNYFH ALENGYRDIP YHNRVHATDV LHAVWYLTTQ 720 721 PVPGLPSLMT DHGSASDSDS DSGITHSHMG FLVSKTYTVS EDGYGCLSGL IPALELMALY 780 781 VAAAMHDYDH PGRTNAFLVA TSAPQAVLYN DRSVLENHHA AAAWNLFLSQ PEYNFLVNLD 840 841 HVEFKRFRFL VIEAILATDL KKHFDFLAEF NAKVGDDPST GIDWSNENDR LLVCQMCIKL 900 901 ADINGPLKCK ELHLQWTEGI VNEFYEQGDE ESSLGLPISP FMDRAAPQLA KLQESFITHI 960 961 VGPLCNSYDS ASLMPGRWVE PNPEEEGPEV GENEEEDEED TAEEDTSTCS EASRKYSNKR 1020 1021 RKVFCQITQH LLENHEMWKK VIAEENQKQA QGAEPVHLNN VAEPILAIHE EEEESGSREE 1080 1081 LIEGEDPEEE L 1091 |
| Nucleotide CDS Sequence (FASTA) |
1 TGGGTGAGAC TGATGTTTAC AAAAATATGG AGTTCGCAAA GACTCCGGAG TGCGGTGTGT 60 61 GTGGGCTCGC TTTCGTTTTT TCTCGCTCTG CTGGTCAAAT GTGCAGACTG GAAAGCTGAT 120 121 GCCAGCAGCA GCGCTGACAG CAGACTCTCG CATTCATCGT CTCCCCTTCA CTTCGTTTCA 180 181 GGCTGCGCAG CAGAGCTGTT GCAAACTTGC TGGAGTGTGG TTTCGCCATT GTTCACCCTT 240 241 GTATGTGCCT TCTTTTGGGT CGGTGTGTAC TTAATCCGCT GCGGGGTTCT AATCCAGACC 300 301 GCCATCTCCC TCCTAACCTT GTGCCACCTG GGCGAAGTAG CGGCGTGGTC TCTTCTGGAT 360 361 GGGACAGATG AGCAGCTGTT TTCATTCACG ACAGCGGCCG TTGTTGTGCT CCTCTGCGTG 420 421 GCCACCGGCG CACTCATGGT AGTACGGTTG AATCAGGGCA TATCGGTGAT CGTTTTCATC 480 481 AGCGTAGTCA GGACTATCTC ACTCTTCTCT CTGCACAAAG TGCGGGCCAC TTGGAGACCA 540 541 TACGTAGCGT ACCTGGTTGG AGTGCTGGGC ATCCTGCTGG CGAGGTATGC TGAAAAGCTC 600 601 CTTCCCAACC AAGGGAGACA CAAGGAGGGC TGCACCCCTG TGACTGAGGC CAGGGAAGAG 660 661 ATCCCTGTAT TTAAAAGGCG CAGGAGGTCC AGTTCTGTGA TAGCCTCAGA CATGGCACAC 720 721 AGTCAGTCCA ACAGCAAGTC ACATCGCCGG ACCTCTCTGC CATGCATCCA AAGAGACCAG 780 781 ATGCTCCCCC GTTCGGATTG GGACCACAAG AGAGGCTCCC GAGGATCACA GTCATCAGGC 840 841 ACAACTGTCA TGGTGGACAT AGCAGTGATG GGAGAAGCCC ATGGACTAAT TACAGACCTG 900 901 CTGGCTGACC CCTCTCTCCC ACCCAACACC TGCACGTCTC TGCGGGCCGT CAGCAACATG 960 961 CTTACCACCC AGCTCACTTT CCAGCCCCTG CACCGGCCAC GCCCTGCCCC CCTGCATAAC 1020 1021 CCCAGCGATG TCTACACCTG CTCTGACTCA GAGGAGGTAC CTGAGAAAGG AGAGAAGACA 1080 1081 TCCATCCACA AGCGTCTGAG GCGGAGCCTC CACCCTGGCC TTTTGAGGAG GATCTCTTCC 1140 1141 ACGTGGACCA CCACCACGTC TGCCACAGGA CTTCCCACAA TTGAGCCGGG ACCCGTGCGA 1200 1201 AGGGACCGCA GCGCCAGCAT CAAACCCTAT CATGAAGCAC TCACGTGCAG GTACCTGAGC 1260 1261 CACACCTGTT TCACACCCCA GATTTTAGTC ACATTGGAAT TTCAAAGGAG TTTCAGCTTG 1320 1321 AAATTTTTCA GCTGTGCATG CTCACCCCAT GTTAAAAATA AAGAGCAGCG GAGGCCTGGT 1380 1381 TCCCAAGTCC CATATTCTTA TGCGCAGCCC AGCAGCATGC CCCAGCAAGC AGCAACCTGC 1440 1441 CAACACGTCA TTTCTCAAGG AGTAATAAGG ACATTAGGCT TCTTTTTTTC CCCCTCCCTC 1500 1501 GTTTTTCCAT CATGTCAGCC TTCAATGACG TACACTGGCA GAGGCCAGCC GGAGCTTACG 1560 1561 GCACGGCTCA AGCCATACAA GAAGAAGTCC TCAAAAAGTT GTGGGAGACC ATACATCAGA 1620 1621 CTGAACCACG GTGAGGGCTC TTTAGACAAG GGAGACAGGA TACCACGTTC AGAAAGAACT 1680 1681 AAACCAGCAG AGGACCAAGT GGTTGTGTCA TCAGACTATG ACAGCACCCA TGAAGCCAAC 1740 1741 CACAGTGACA GCAGTGATGT AGCACATACA GAGGACGATG CAGAAGAAGG AAAAAACTCC 1800 1801 CAGAATGTCA TCCTCCATGC ACTAATACCT CCCGAGTTGT TACTCACGCA GGACAAACCA 1860 1861 ATCTTGGCAC CAGAGCCTTT AATAATGGAG GGCCTGGAAC CTCTGATGAG TCAGCTGAAC 1920 1921 AATTGGAACT TCCCCATCTT CACCTTGATA GAGAAGACCA ATGGGAAATG TGGACGAATC 1980 1981 CTCAGTCAGG TATCTTATAG GCTCTTTGAG GACACTGGCC TGTTTGAGAC TTTTAAGATC 2040 2041 CCCGTAAAAG AATTCATGAA CTACTTCCAT GCCCTTGAGA ATGGTTACAG AGACATACCA 2100 2101 TATCACAACA GGGTCCATGC CACAGATGTG CTTCACGCAG TCTGGTACCT CACCACGCAG 2160 2161 CCTGTGCCTG GCCTGCCCAG CCTCATGACT GACCACGGCT CTGCCAGTGA CTCAGACTCC 2220 2221 GACAGTGGAA TAACACACAG TCACATGGGC TTCCTGGTTT CAAAGACCTA CACTGTGTCA 2280 2281 GAAGATGGTT ACGGCTGCCT GTCAGGCCTC ATACCTGCTC TGGAGCTCAT GGCTCTTTAC 2340 2341 GTGGCTGCCG CCATGCACGA TTATGATCAC CCAGGGCGGA CAAACGCTTT CCTCGTGGCC 2400 2401 ACCAGCGCCC CACAGGCGGT GCTCTACAAT GACCGCTCAG TTTTGGAAAA CCACCACGCT 2460 2461 GCCGCAGCCT GGAACCTCTT CCTGTCACAG CCAGAGTACA ACTTCCTGGT CAATCTGGAC 2520 2521 CATGTGGAGT TCAAACGTTT CCGTTTCCTG GTCATTGAGG CCATACTGGC CACTGATCTG 2580 2581 AAGAAGCATT TTGACTTCCT AGCTGAGTTC AATGCCAAGG TAGGTGATGA TCCATCTACA 2640 2641 GGTATCGACT GGTCTAACGA GAATGACAGG TTGCTAGTCT GCCAGATGTG CATCAAACTC 2700 2701 GCTGATATAA ATGGGCCTCT GAAGTGCAAG GAGCTACATC TGCAATGGAC AGAGGGCATT 2760 2761 GTCAATGAGT TCTATGAACA GGGTGATGAG GAGTCCAGCC TCGGCCTTCC TATCAGCCCT 2820 2821 TTCATGGATC GAGCAGCCCC ACAGCTGGCC AAACTCCAGG AATCCTTCAT CACCCACATC 2880 2881 GTTGGACCAC TGTGTAACTC CTATGACTCG GCCAGCCTCA TGCCTGGACG ATGGGTGGAA 2940 2941 CCCAACCCGG AGGAGGAGGG GCCAGAGGTT GGAGAGAATG AGGAGGAGGA TGAGGAGGAT 3000 3001 ACTGCAGAGG AAGACACATC CACCTGCTCG GAAGCGTCCC GTAAGTATTC AAATAAGAGG 3060 3061 AGGAAAGTCT TCTGCCAGAT CACGCAGCAC CTGCTGGAGA ACCACGAGAT GTGGAAAAAG 3120 3121 GTGATTGCAG AAGAGAACCA AAAACAGGCA CAAGGAGCGG AGCCTGTCCA TTTAAACAAT 3180 3181 GTAGCTGAAC CTATTCTGGC TATTCATGAA GAGGAAGAGG AGTCAGGTAG CCGAGAGGAG 3240 3241 CTGATAGAAG GAGAGGATCC AGAGGAGGAA CTG 3273 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ten-2201 | Tetraodon nigroviridis | 79.09 | 0.0 | 1387 |
| LLPS-Gaa-0522 | Gasterosteus aculeatus | 78.24 | 0.0 | 1496 |
| LLPS-Poa-3278 | Pongo abelii | 77.69 | 6e-111 | 376 |
| LLPS-Tar-0498 | Takifugu rubripes | 74.55 | 0.0 | 1405 |
| LLPS-Mal-2145 | Mandrillus leucophaeus | 67.65 | 1e-06 | 57.4 |
| LLPS-Leo-2420 | Lepisosteus oculatus | 67.23 | 0.0 | 1297 |
| LLPS-Asm-0319 | Astyanax mexicanus | 65.76 | 0.0 | 956 |
| LLPS-Dar-3645 | Danio rerio | 65.44 | 0.0 | 1137 |
| LLPS-Sah-1959 | Sarcophilus harrisii | 64.42 | 0.0 | 914 |
| LLPS-Ova-1304 | Ovis aries | 64.3 | 0.0 | 912 |
| LLPS-Lac-2051 | Latimeria chalumnae | 64.02 | 0.0 | 967 |
| LLPS-Myl-0454 | Myotis lucifugus | 63.97 | 0.0 | 892 |
| LLPS-Meg-0354 | Meleagris gallopavo | 63.95 | 0.0 | 919 |
| LLPS-Loa-2211 | Loxodonta africana | 63.67 | 0.0 | 902 |
| LLPS-Bot-3714 | Bos taurus | 63.59 | 0.0 | 886 |
| LLPS-Fud-3400 | Fukomys damarensis | 63.4 | 0.0 | 1016 |
| LLPS-Anc-3233 | Anolis carolinensis | 63.17 | 0.0 | 889 |
| LLPS-Gog-4140 | Gorilla gorilla | 63.08 | 0.0 | 998 |
| LLPS-Gaga-4043 | Gallus gallus | 63.05 | 0.0 | 948 |
| LLPS-Fia-3827 | Ficedula albicollis | 63.01 | 0.0 | 924 |
| LLPS-Otg-2579 | Otolemur garnettii | 62.64 | 0.0 | 773 |
| LLPS-Tag-0791 | Taeniopygia guttata | 62.47 | 0.0 | 911 |
| LLPS-Pes-3653 | Pelodiscus sinensis | 62.45 | 0.0 | 875 |
| LLPS-Scf-3174 | Scleropages formosus | 62.31 | 0.0 | 806 |
| LLPS-Fec-4531 | Felis catus | 61.92 | 0.0 | 841 |
| LLPS-Icp-0311 | Ictalurus punctatus | 61.43 | 0.0 | 1091 |
| LLPS-Cap-1350 | Cavia porcellus | 61.43 | 0.0 | 1028 |
| LLPS-Orc-2726 | Oryctolagus cuniculus | 61.37 | 0.0 | 1043 |
| LLPS-Urm-2578 | Ursus maritimus | 61.35 | 0.0 | 956 |
| LLPS-Mod-4137 | Monodelphis domestica | 61.23 | 0.0 | 1024 |
| LLPS-Mup-1821 | Mustela putorius furo | 61.06 | 0.0 | 994 |
| LLPS-Sus-2661 | Sus scrofa | 61.03 | 0.0 | 1028 |
| LLPS-Paa-0435 | Papio anubis | 60.96 | 0.0 | 1011 |
| LLPS-Maf-3585 | Macaca fascicularis | 60.96 | 0.0 | 1011 |
| LLPS-Cea-3299 | Cercocebus atys | 60.96 | 0.0 | 1011 |
| LLPS-Mam-2671 | Macaca mulatta | 60.96 | 0.0 | 1012 |
| LLPS-Man-4650 | Macaca nemestrina | 60.96 | 0.0 | 1012 |
| LLPS-Caf-0353 | Canis familiaris | 60.88 | 0.0 | 1007 |
| LLPS-Nol-4054 | Nomascus leucogenys | 60.86 | 0.0 | 1019 |
| LLPS-Ran-2921 | Rattus norvegicus | 60.84 | 0.0 | 1005 |
| LLPS-Mea-1885 | Mesocricetus auratus | 60.83 | 0.0 | 977 |
| LLPS-Pap-1028 | Pan paniscus | 60.78 | 0.0 | 1008 |
| LLPS-Aon-2475 | Aotus nancymaae | 60.59 | 0.0 | 995 |
| LLPS-Pof-2012 | Poecilia formosa | 60.55 | 0.0 | 1068 |
| LLPS-Mum-4405 | Mus musculus | 60.49 | 0.0 | 999 |
| LLPS-Scm-1673 | Scophthalmus maximus | 60.38 | 0.0 | 1074 |
| LLPS-Xim-2909 | Xiphophorus maculatus | 60.29 | 0.0 | 1079 |
| LLPS-Anp-2696 | Anas platyrhynchos | 58.49 | 0.0 | 813 |
| LLPS-Orl-1896 | Oryzias latipes | 58.46 | 0.0 | 1068 |
| LLPS-Chs-1878 | Chlorocebus sabaeus | 58.15 | 0.0 | 1011 |
| LLPS-Ict-2487 | Ictidomys tridecemlineatus | 57.98 | 0.0 | 1051 |
| LLPS-Eqc-3805 | Equus caballus | 57.85 | 0.0 | 1026 |
| LLPS-Pat-2074 | Pan troglodytes | 57.85 | 0.0 | 1021 |
| LLPS-Hos-2734 | Homo sapiens | 57.85 | 0.0 | 1023 |
| LLPS-Caj-4407 | Callithrix jacchus | 57.84 | 0.0 | 996 |
| LLPS-Tut-1872 | Tursiops truncatus | 33.05 | 5e-46 | 182 |
| LLPS-Rhb-1036 | Rhinopithecus bieti | 33.05 | 2e-42 | 172 |
| LLPS-Cas-3572 | Carlito syrichta | 32.52 | 2e-38 | 157 |
| LLPS-Xet-0274 | Xenopus tropicalis | 30.21 | 7e-35 | 144 |
| LLPS-Dio-1120 | Dipodomys ordii | 30.17 | 2e-33 | 142 |
| LLPS-Aim-0805 | Ailuropoda melanoleuca | 30.03 | 9e-33 | 138 |
| LLPS-Ora-0156 | Ornithorhynchus anatinus | 29.74 | 5e-28 | 123 |