• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ori-1190
H2B.2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Histone H2B.2
Gene Name: H2B.2, OsI_028676
Ensembl Gene: BGIOSGA028894
Ensembl Protein: BGIOSGA028894-PA
Organism: Oryza indica
Taxa ID: 39946
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblBGIOSGA028894-TABGIOSGA028894-PA
UniProtA2YWI3, H2B2_ORYSI
GeneBankCM000133EAZ07444.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAPKAEKKPA  EKKPAEEKAG  EKAPAAGKKP  KAEKRLPASK  GEKGGEGKKE  RGRKKAKKSV  60
61    ETYKIYIFKV  LKQVHPDIGI  SSKAMSIMNS  FINDIFEKLA  GEAAKLARYN  KKPTITSREI  120
121   QTSVRLVLPG  ELAKHAVSEG  TKAVTKFTSS  150
Nucleotide CDS Sequence (FASTA)
1     ATGGCGCCCA  AGGCCGAGAA  GAAGCCCGCG  GAGAAGAAGC  CGGCGGAGGA  GAAGGCCGGC  60
61    GAGAAGGCGC  CCGCGGCCGG  GAAGAAGCCC  AAGGCCGAGA  AGCGGCTGCC  GGCGTCCAAG  120
121   GGGGAGAAGG  GCGGCGAGGG  CAAGAAGGAG  CGCGGCAGGA  AGAAGGCCAA  GAAGAGCGTC  180
181   GAGACCTACA  AGATATACAT  CTTCAAGGTG  CTCAAGCAGG  TGCACCCGGA  CATCGGGATC  240
241   TCCTCCAAGG  CCATGTCAAT  CATGAACTCG  TTCATCAACG  ACATCTTCGA  GAAGCTCGCC  300
301   GGCGAGGCCG  CCAAGCTCGC  CAGGTACAAC  AAGAAGCCCA  CCATCACCTC  CAGGGAGATC  360
361   CAGACCTCCG  TCCGCCTCGT  CCTCCCCGGC  GAGCTCGCCA  AGCACGCCGT  CTCCGAGGGC  420
421   ACCAAGGCCG  TCACCAAGTT  CACCAGCTCT  TAG  453

▼ KEYWORD

ID
Family
Acetylation
Chromosome
Complete proteome
DNA-binding
Isopeptide bond
Nucleosome core
Nucleus
Reference proteome
Ubl conjugation

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleosome
Cellular Component
Nucleus
Molecular Function
DNA binding
Molecular Function
Protein heterodimerization activity

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Brd-2289Brachypodium distachyon100.06e-59 186
LLPS-Lep-1932Leersia perrieri100.05e-59 187
LLPS-Orni-1442Oryza nivara100.03e-59 187
LLPS-Orb-2296Oryza barthii100.03e-59 187
LLPS-Zem-0768Zea mays100.05e-59 186
LLPS-Orm-1555Oryza meridionalis100.03e-59 187
LLPS-Sob-2331Sorghum bicolor100.05e-59 186
LLPS-Ors-0636Oryza sativa100.03e-58 187
LLPS-Orp-0440Oryza punctata99.143e-59 187
LLPS-Hov-0129Hordeum vulgare98.92e-58 186
LLPS-Orbr-1237Oryza brachyantha98.282e-58 185
LLPS-Tra-0340Triticum aestivum97.83e-58 184
LLPS-Orgl-1599Oryza glumaepatula97.83e-57 182
LLPS-Tru-1544Triticum urartu97.89e-58 183
LLPS-Org-1624Oryza glaberrima97.83e-57 182
LLPS-Orr-2267Oryza rufipogon97.82e-57 182
LLPS-Dac-2415Daucus carota96.73e-57 182
LLPS-Glm-1366Glycine max95.69e-56 178
LLPS-Coc-2058Corchorus capsularis95.61e-55 178
LLPS-Art-1751Arabidopsis thaliana95.63e-56 179
LLPS-Arl-1943Arabidopsis lyrata94.519e-56 178
LLPS-Thc-1720Theobroma cacao94.513e-55 177
LLPS-Amt-0786Amborella trichopoda94.511e-55 178
LLPS-Gor-2468Gossypium raimondii94.514e-54 176
LLPS-Viv-2502Vitis vinifera94.513e-55 177
LLPS-Sot-1201Solanum tuberosum94.442e-54 175
LLPS-Mae-1346Manihot esculenta94.441e-54 175
LLPS-Met-1443Medicago truncatula93.414e-55 176
LLPS-Cus-2209Cucumis sativus93.417e-55 176
LLPS-Via-1619Vigna angularis93.417e-55 176
LLPS-Hea-0587Helianthus annuus93.414e-55 176
LLPS-Sol-0691Solanum lycopersicum93.411e-54 175
LLPS-Prp-2053Prunus persica93.419e-55 176
LLPS-Nia-1944Nicotiana attenuata93.418e-55 176
LLPS-Phv-0869Phaseolus vulgaris93.411e-54 175
LLPS-Pot-2167Populus trichocarpa93.334e-54 174
LLPS-Brn-0240Brassica napus92.313e-54 174
LLPS-Bro-1634Brassica oleracea92.313e-54 174
LLPS-Brr-0650Brassica rapa92.313e-54 174
LLPS-Php-2112Physcomitrella patens91.213e-54 174
LLPS-Sei-2413Setaria italica89.664e-59 187
LLPS-Ova-2018Ovis aries82.225e-49 160
LLPS-Myl-3771Myotis lucifugus82.226e-49 160
LLPS-Mup-2374Mustela putorius furo82.226e-49 160
LLPS-Ere-0769Erinaceus europaeus82.221e-48 159
LLPS-Ran-0001Rattus norvegicus82.225e-49 160
LLPS-Dio-0242Dipodomys ordii82.226e-49 160
LLPS-Mea-2373Mesocricetus auratus82.226e-49 160
LLPS-Ict-2438Ictidomys tridecemlineatus82.225e-49 160
LLPS-Caf-3343Canis familiaris82.223e-49 161
LLPS-Otg-0117Otolemur garnettii82.221e-48 159
LLPS-Loa-2482Loxodonta africana82.227e-49 160
LLPS-Fec-4151Felis catus82.226e-49 160
LLPS-Urm-1113Ursus maritimus82.224e-49 160
LLPS-Aim-1800Ailuropoda melanoleuca81.113e-48 158
LLPS-Scf-2797Scleropages formosus81.118e-49 160
LLPS-Xim-0850Xiphophorus maculatus81.116e-49 160
LLPS-Asm-2976Astyanax mexicanus81.111e-48 160
LLPS-Gog-4470Gorilla gorilla81.118e-48 157
LLPS-Sus-1504Sus scrofa81.117e-48 157
LLPS-Sah-3850Sarcophilus harrisii81.116e-49 160
LLPS-Mum-4864Mus musculus81.117e-48 157
LLPS-Eqc-0395Equus caballus81.111e-47 156
LLPS-Ten-3753Tetraodon nigroviridis81.111e-48 159
LLPS-Orc-3782Oryctolagus cuniculus81.114e-48 158
LLPS-Pes-3778Pelodiscus sinensis81.116e-49 160
LLPS-Anp-0630Anas platyrhynchos81.116e-49 160
LLPS-Lac-1123Latimeria chalumnae81.119e-49 160
LLPS-Dar-2066Danio rerio81.117e-49 160
LLPS-Pof-4102Poecilia formosa81.118e-49 159
LLPS-Tum-1344Tuber melanosporum80.08e-47 155
LLPS-Asf-0233Aspergillus flavus80.07e-47 155
LLPS-Paa-3867Papio anubis80.02e-48 159
LLPS-Mal-3522Mandrillus leucophaeus80.02e-47 156
LLPS-Bot-0242Bos taurus80.09e-49 159
LLPS-Tut-2288Tursiops truncatus80.09e-49 159
LLPS-Icp-2130Ictalurus punctatus80.03e-48 158
LLPS-Fud-1950Fukomys damarensis80.09e-49 159
LLPS-Asn-1385Aspergillus nidulans80.07e-47 155
LLPS-Asni-1247Aspergillus niger80.09e-47 155
LLPS-Cea-0127Cercocebus atys80.08e-49 160
LLPS-Aon-0353Aotus nancymaae80.09e-49 159
LLPS-Chs-4436Chlorocebus sabaeus80.02e-48 159
LLPS-Asc-0571Aspergillus clavatus80.09e-47 155
LLPS-Maf-1670Macaca fascicularis80.09e-49 159
LLPS-Nol-0376Nomascus leucogenys80.01e-48 159
LLPS-Dos-0967Dothistroma septosporum80.08e-47 155
LLPS-Asfu-0898Aspergillus fumigatus80.02e-46 154
LLPS-Cas-1504Carlito syrichta80.01e-48 159
LLPS-Mam-0353Macaca mulatta80.09e-49 159
LLPS-Poa-3861Pongo abelii80.01e-48 159
LLPS-Rhb-2324Rhinopithecus bieti80.09e-49 159
LLPS-Nef-1156Neosartorya fischeri80.02e-46 154
LLPS-Man-3219Macaca nemestrina80.02e-48 159
LLPS-Ast-1331Aspergillus terreus80.09e-47 155
LLPS-Hos-2105Homo sapiens80.01e-48 159
LLPS-Pap-3472Pan paniscus80.01e-48 159
LLPS-Pat-4057Pan troglodytes80.09e-49 159
LLPS-Gaa-2312Gasterosteus aculeatus78.891e-47 156
LLPS-Caj-4009Callithrix jacchus78.893e-48 158
LLPS-Cis-0294Ciona savignyi77.54e-1573.9
LLPS-Cae-0341Caenorhabditis elegans76.672e-47 156
LLPS-Sac-1650Saccharomyces cerevisiae75.563e-45 150
LLPS-Scp-0271Schizosaccharomyces pombe75.561e-44 149
LLPS-Scc-1455Schizosaccharomyces cryophilus75.561e-44 149
LLPS-Spr-0846Sporisorium reilianum74.441e-44 149
LLPS-Usm-0062Ustilago maydis74.441e-44 149
LLPS-Yal-1585Yarrowia lipolytica71.917e-42 142