DrLLPS - Data resource of LLPS

LLPS-Orgl-0209

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Imidazole glycerol phosphate synthase hisHF
Ensembl Gene:	OGLUM03G11000
Ensembl Protein:	OGLUM03G11000.1
Organism:	Oryza glumaepatula
Taxa ID:	40148
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Arabidopsis thaliana	LLPS-Art-0543	Q9SZ30	Client	Nucleolus	71.20	0.0	802

▼ FUNCTION

IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	OGLUM03G11000.1	OGLUM03G11000.1
UniProt		A0A0D9Z4V5, A0A0D9Z4V5_9ORYZ

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAAATSINAV PCSAGRPKRR SQRRGASTVA VRASGDASTV TLLDYGAGNV RSVRNAIRHL 60 61 GFGIRDVRSP EDILAADRLV FPGVGAFGSA MDVLTRSGMA DALREYIRRD RPFLGICLGL 120 121 QLLFDSSEEN GLISGLGVIP GVVRRFDSSK GLIVPHIGWN ALEITKDTQL LKGAEGHHVY 180 181 FVHSYHALPV RNSSFLDALS LVDLWNSDEN KEWISSVCNY GESFISSISM GNIQAVQFHP 240 241 EKSGATGLSI LKNFLSPNSS GSKVPSRRKA SNLAKRVIAC LDVRSNDSGD LVVTKGDQYD 300 301 VRNLGKPVDL ASQYYIDGAD EVSFLNITGF RDFPLGDLPM LEVLRCASEK VFVPLTVGGG 360 361 IRDFTDANGR YYSSLEVASE YFRSGADKIS IGSNAVFAAE AYLQTGVKTG KSSLEQISRV 420 421 YGNQAVVVSI DPRRVYVKNP EEVQFKTVKV SNKGPLGEEY AWYQCTVSGG RDSRPIGAYE 480 481 LAKAVEELGA GEILLNCIDC DDAVTIPVIA SSGAGIVEHF SEVFEKTNAS AALAAGIFHR 540 541 KEVPISAVKE HLVDAGVEVR V 561

Protein Sequence (FASTA)

1     MAAATSINAV  PCSAGRPKRR  SQRRGASTVA  VRASGDASTV  TLLDYGAGNV  RSVRNAIRHL  60
61    GFGIRDVRSP  EDILAADRLV  FPGVGAFGSA  MDVLTRSGMA  DALREYIRRD  RPFLGICLGL  120
121   QLLFDSSEEN  GLISGLGVIP  GVVRRFDSSK  GLIVPHIGWN  ALEITKDTQL  LKGAEGHHVY  180
181   FVHSYHALPV  RNSSFLDALS  LVDLWNSDEN  KEWISSVCNY  GESFISSISM  GNIQAVQFHP  240
241   EKSGATGLSI  LKNFLSPNSS  GSKVPSRRKA  SNLAKRVIAC  LDVRSNDSGD  LVVTKGDQYD  300
301   VRNLGKPVDL  ASQYYIDGAD  EVSFLNITGF  RDFPLGDLPM  LEVLRCASEK  VFVPLTVGGG  360
361   IRDFTDANGR  YYSSLEVASE  YFRSGADKIS  IGSNAVFAAE  AYLQTGVKTG  KSSLEQISRV  420
421   YGNQAVVVSI  DPRRVYVKNP  EEVQFKTVKV  SNKGPLGEEY  AWYQCTVSGG  RDSRPIGAYE  480
481   LAKAVEELGA  GEILLNCIDC  DDAVTIPVIA  SSGAGIVEHF  SEVFEKTNAS  AALAAGIFHR  540
541   KEVPISAVKE  HLVDAGVEVR  V  561

▼ KEYWORD

ID	Family
KW-0028	Amino-acid biosynthesis
KW-0150	Chloroplast
KW-0181	Complete proteome
KW-0315	Glutamine amidotransferase
KW-0368	Histidine biosynthesis
KW-0378	Hydrolase
KW-0456	Lyase
KW-0511	Multifunctional enzyme
KW-0934	Plastid
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0009507	Cellular Component	Chloroplast
GO:0004359	Molecular Function	Glutaminase activity
GO:0000107	Molecular Function	Imidazoleglycerol-phosphate synthase activity
GO:0016833	Molecular Function	Oxo-acid-lyase activity
GO:0006541	Biological Process	Glutamine metabolic process
GO:0000105	Biological Process	Histidine biosynthetic process

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Orb-1635	Oryza barthii	95.25	0.0	1083
LLPS-Orr-1545	Oryza rufipogon	95.25	0.0	1083
LLPS-Orni-1951	Oryza nivara	95.07	0.0	1082
LLPS-Ori-2279	Oryza indica	92.31	0.0	1070
LLPS-Ors-0787	Oryza sativa	92.31	0.0	1070
LLPS-Org-1669	Oryza glaberrima	91.06	0.0	1061
LLPS-Orm-2004	Oryza meridionalis	90.97	0.0	1037
LLPS-Orbr-2038	Oryza brachyantha	88.89	0.0	1032
LLPS-Via-1859	Vigna angularis	88.1	2e-12	74.3
LLPS-Lep-1040	Leersia perrieri	87.88	0.0	1020
LLPS-Sei-1292	Setaria italica	84.86	0.0	987
LLPS-Brd-2306	Brachypodium distachyon	83.59	0.0	983
LLPS-Tra-2508	Triticum aestivum	83.42	0.0	978
LLPS-Orp-1760	Oryza punctata	82.75	0.0	926
LLPS-Sob-1400	Sorghum bicolor	82.71	0.0	964
LLPS-Hov-0245	Hordeum vulgare	80.76	0.0	969
LLPS-Vir-1449	Vigna radiata	79.75	2e-173	508
LLPS-Tru-0290	Triticum urartu	78.78	0.0	912
LLPS-Dac-1699	Daucus carota	77.88	1e-163	483
LLPS-Zem-0460	Zea mays	76.39	2e-108	333
LLPS-Sol-2278	Solanum lycopersicum	73.73	0.0	816
LLPS-Coc-2160	Corchorus capsularis	73.32	0.0	829
LLPS-Gor-2772	Gossypium raimondii	73.08	0.0	805
LLPS-Hea-2560	Helianthus annuus	72.63	0.0	808
LLPS-Nia-2637	Nicotiana attenuata	72.14	0.0	756
LLPS-Mae-2464	Manihot esculenta	72.13	0.0	792
LLPS-Mua-2331	Musa acuminata	72.0	0.0	813
LLPS-Viv-0271	Vitis vinifera	71.98	0.0	762
LLPS-Sot-2152	Solanum tuberosum	71.93	0.0	816
LLPS-Arl-2967	Arabidopsis lyrata	71.79	0.0	796
LLPS-Prp-2454	Prunus persica	71.75	0.0	813
LLPS-Brn-0918	Brassica napus	71.38	0.0	804
LLPS-Bro-0604	Brassica oleracea	71.38	0.0	804
LLPS-Art-0543	Arabidopsis thaliana	71.2	0.0	803
LLPS-Amt-1100	Amborella trichopoda	70.67	0.0	795
LLPS-Phv-2458	Phaseolus vulgaris	70.54	0.0	803
LLPS-Glm-2750	Glycine max	70.49	0.0	804
LLPS-Pot-1333	Populus trichocarpa	70.47	0.0	802
LLPS-Met-1149	Medicago truncatula	70.24	0.0	810
LLPS-Cus-1527	Cucumis sativus	70.16	1e-179	524
LLPS-Thc-0671	Theobroma cacao	69.26	0.0	791
LLPS-Brr-2114	Brassica rapa	68.13	0.0	762
LLPS-Php-2150	Physcomitrella patens	67.75	0.0	732
LLPS-Sem-0029	Selaginella moellendorffii	65.08	0.0	718
LLPS-Chr-1493	Chlamydomonas reinhardtii	64.71	3e-19	95.1
LLPS-Osl-0229	Ostreococcus lucimarinus	57.69	0.0	635
LLPS-Asf-0804	Aspergillus flavus	54.43	3e-79	256
LLPS-Abg-1662	Absidia glauca	54.01	0.0	569
LLPS-Cog-1354	Colletotrichum gloeosporioides	53.12	3e-48	171
LLPS-Dos-1096	Dothistroma septosporum	51.36	1e-148	443
LLPS-Chc-0166	Chondrus crispus	51.18	5e-177	524
LLPS-Scs-0012	Sclerotinia sclerotiorum	51.18	0.0	528
LLPS-Pytr-1464	Pyrenophora triticirepentis	51.09	2e-128	389
LLPS-Mao-0891	Magnaporthe oryzae	51.07	1e-180	528
LLPS-Blg-1415	Blumeria graminis	51.0	3e-179	525
LLPS-Zyt-1427	Zymoseptoria tritici	51.0	5e-175	513
LLPS-Scp-1404	Schizosaccharomyces pombe	50.63	8e-176	515
LLPS-Map-1305	Magnaporthe poae	50.45	3e-174	512
LLPS-Nec-1448	Neurospora crassa	50.09	3e-176	517
LLPS-Asfu-0820	Aspergillus fumigatus	50.09	1e-176	518
LLPS-Nef-1148	Neosartorya fischeri	50.09	1e-177	521
LLPS-Aso-1006	Aspergillus oryzae	50.0	1e-175	516
LLPS-Scc-0936	Schizosaccharomyces cryophilus	49.82	6e-173	508
LLPS-Fuv-0572	Fusarium verticillioides	49.73	1e-174	513
LLPS-Fuo-0769	Fusarium oxysporum	49.73	5e-175	513
LLPS-Ast-1229	Aspergillus terreus	49.73	6e-176	516
LLPS-Trr-0759	Trichoderma reesei	49.73	7e-174	511
LLPS-Lem-0960	Leptosphaeria maculans	49.64	1e-176	518
LLPS-Fus-1324	Fusarium solani	49.64	4e-174	511
LLPS-Pug-1134	Puccinia graminis	49.57	1e-167	496
LLPS-Mel-0863	Melampsora laricipopulina	49.49	2e-170	503
LLPS-Asn-0336	Aspergillus nidulans	49.47	2e-173	510
LLPS-Ved-0514	Verticillium dahliae	49.47	8e-176	516
LLPS-Asc-0554	Aspergillus clavatus	49.37	3e-173	509
LLPS-Asni-0478	Aspergillus niger	49.29	2e-174	512
LLPS-Tum-1225	Tuber melanosporum	49.28	2e-173	509
LLPS-Scj-1159	Schizosaccharomyces japonicus	49.1	3e-173	509
LLPS-Phn-1034	Phaeosphaeria nodorum	49.1	3e-176	517
LLPS-Sac-1345	Saccharomyces cerevisiae	49.02	2e-167	494
LLPS-Trv-0524	Trichoderma virens	49.01	2e-172	507
LLPS-Beb-1435	Beauveria bassiana	49.01	3e-170	501
LLPS-Yal-1478	Yarrowia lipolytica	48.92	1e-163	484
LLPS-Coo-0947	Colletotrichum orbiculare	48.92	2e-167	494
LLPS-Pyt-1389	Pyrenophora teres	48.84	2e-174	512
LLPS-Cogr-1395	Colletotrichum graminicola	48.75	2e-171	504
LLPS-Put-1099	Puccinia triticina	47.98	5e-151	454
LLPS-Gag-0150	Gaeumannomyces graminis	47.91	2e-160	477
LLPS-Asg-0523	Ashbya gossypii	47.06	5e-159	473
LLPS-Crn-0514	Cryptococcus neoformans	46.23	3e-146	442
LLPS-Kop-1287	Komagataella pastoris	45.95	2e-154	461
LLPS-Miv-0582	Microbotryum violaceum	45.65	5e-159	474
LLPS-Spr-0676	Sporisorium reilianum	43.99	8e-154	462
LLPS-Usm-0393	Ustilago maydis	43.81	3e-155	466
LLPS-Gas-0452	Galdieria sulphuraria	35.18	2e-35	140
LLPS-Cym-1059	Cyanidioschyzon merolae	34.29	2e-32	131

LLPS-Orgl-0209

Protein Sequence

Nucleotide Sequence