LLPS-Orc-a189
PYGL
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Alpha-1,4 glucan phosphorylase |
| Gene Name: | PYGL |
| Ensembl Gene: | ENSOCUG00000015527.3 |
| Ensembl Protein: | ENSOCUP00000013341.3 |
| Organism: | Oryctolagus cuniculus |
| Taxa ID: | 9986 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOCUT00000015527.3 | ENSOCUP00000013341.3 |
| UniProt | G1T9M7, G1T9M7_RABIT | |
| GeneBank | AAGW02050059, AAGW02050056, AAGW02050058, AAGW02050055, AAGW02050057 | |
| RefSeq | XM_002718303.3 | XP_002718349.1 |
| Entrez | 100347428 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAKPLSDQER RRQISIRGIV GVENVAELKK GFNRHLHFTL VKDRNVATPR DYFFALAHTV 60 61 RDHLVGRWIR TQQHYYDKCP KRVYYLSLEF YMGRTLQNTM INLGLQNACD EAIYQLGLDM 120 121 EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEYGIFNQK IRDGWQVEEA 180 181 DDWLRHGNPW EKARPEFMLP VHFYGKVEHT QTGTKWVDTQ VVLALPYDTP VPGYMNNTVN 240 241 TMRLWSARAP NDFNLRDFNV GDYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV 300 301 VAATLQDVIR RFKASKFGSS SSAGAVFDAF PEQVAIQLND THPALAIPEL MRIFVDIEKL 360 361 PWAKAWDITR KTFAYTNHTV LPEALERWPV ELVEKLLPRH LQIIYEINQK HLDRIVALFP 420 421 RDVERLRRMS LIEEEGGKRI NMAHLCIVGS HAVNGVAKIH SDIIKTQVFK DFSELEPDKF 480 481 QNKTNGITPR RWLLLCNPGL AELIAEKIGE DYVRDLSQLT RLHSFLGDDV FLREIANVKQ 540 541 ENKLKFSQFL EKEYKVKINP SSMFDVHVKR IHEYKRQLLN CLHVITMYNR IKKDPKKLFV 600 601 PRTVIIGGKA APGYHMAKMI IKLITSVAHV VNNDPVVGSK LKVIFLENYR VSLAEKVIPA 660 661 TDLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEENLF IFGMRVEDVA 720 721 ALDKKGYEAK EYYEALPELK LVIDQIDNGF FSPKQPDLFK DLVNMLFHHD RFKVFADYEA 780 781 YVKCQEKVSE LYMNPKAWNT MVLRNIAASG KFSSDRTIKE YARDIWDMEP SDLKISLASE 840 841 PSSGLNAANG N 851 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCAAGC CGCTGAGCGA CCAGGAGAGG CGGCGGCAGA TCAGCATCCG CGGCATCGTG 60 61 GGCGTGGAGA ACGTGGCCGA GCTCAAGAAG GGCTTCAACC GGCACCTGCA TTTCACGCTG 120 121 GTCAAGGACC GCAACGTGGC CACGCCCCGC GATTACTTCT TCGCGCTGGC CCACACCGTG 180 181 CGAGACCACC TGGTGGGCCG CTGGATCCGC ACGCAGCAGC ACTACTACGA CAAGTGCCCC 240 241 AAGAGGGTTT ATTACCTCTC CCTGGAGTTT TACATGGGCC GAACATTGCA GAACACCATG 300 301 ATCAACCTCG GCCTGCAGAA TGCCTGTGAC GAGGCCATCT ACCAGCTTGG CTTGGACATG 360 361 GAAGAGCTGG AAGAAATTGA AGAAGACGCT GGACTTGGCA ATGGCGGTCT CGGAAGGCTG 420 421 GCTGCCTGCT TCTTGGACTC CATGGCCACG CTGGGGCTCG CAGCCTACGG GTACGGCATC 480 481 CGATATGAGT ACGGCATCTT TAACCAGAAG ATCCGAGATG GGTGGCAGGT GGAAGAGGCA 540 541 GATGATTGGC TCAGGCATGG AAACCCCTGG GAGAAGGCCC GCCCTGAGTT CATGCTGCCC 600 601 GTGCACTTCT ATGGAAAAGT GGAGCACACC CAGACCGGGA CCAAGTGGGT CGACACCCAG 660 661 GTGGTCCTGG CCCTGCCTTA TGACACCCCG GTGCCTGGTT ATATGAACAA CACCGTCAAC 720 721 ACCATGCGCC TGTGGTCTGC TCGGGCGCCC AACGACTTTA ACCTCAGAGA CTTTAACGTT 780 781 GGAGACTACA TCCAGGCTGT GCTGGACCGA AACCTGGCGG AGAACATCTC CCGTGTCCTC 840 841 TATCCCAACG ATAATTTTTT TGAAGGGAAG GAGCTCAGGT TGAAGCAGGA GTACTTCGTG 900 901 GTGGCTGCCA CTTTGCAGGA CGTCATCCGA CGCTTCAAAG CCTCCAAGTT CGGCTCCTCC 960 961 AGCAGTGCGG GAGCTGTGTT TGACGCCTTC CCGGAGCAGG TGGCCATCCA GCTGAACGAC 1020 1021 ACCCACCCTG CACTCGCCAT CCCCGAGCTC ATGAGGATTT TTGTGGATAT TGAAAAGCTG 1080 1081 CCCTGGGCCA AGGCCTGGGA CATCACCCGG AAGACGTTCG CCTACACCAA CCACACGGTG 1140 1141 CTCCCGGAAG CGCTGGAGCG CTGGCCCGTG GAGCTGGTGG AGAAGCTGCT CCCGCGACAC 1200 1201 CTGCAGATTA TCTACGAGAT AAACCAGAAG CACTTAGACA GAATCGTGGC CTTGTTCCCT 1260 1261 AGAGATGTTG AGCGCCTGAG GAGGATGTCT CTGATCGAAG AGGAAGGAGG CAAGAGGATC 1320 1321 AACATGGCCC ACCTCTGCAT CGTGGGCTCC CACGCCGTGA ACGGCGTGGC TAAAATCCAC 1380 1381 TCGGACATCA TCAAGACGCA AGTATTCAAG GATTTCAGTG AGCTAGAACC AGACAAGTTC 1440 1441 CAGAATAAAA CCAATGGGAT CACTCCGAGG CGCTGGCTCT TACTCTGCAA CCCGGGGCTG 1500 1501 GCAGAGCTCA TAGCGGAGAA AATCGGGGAA GACTACGTGA GAGACCTGAG CCAGCTGACC 1560 1561 AGGCTGCACA GCTTCCTGGG CGACGATGTC TTCCTGCGGG AAATCGCCAA CGTGAAGCAG 1620 1621 GAGAACAAGC TGAAGTTCTC CCAGTTCCTG GAAAAGGAGT ACAAAGTCAA GATCAACCCC 1680 1681 TCCTCCATGT TTGACGTACA CGTGAAGAGG ATCCACGAGT ACAAGCGGCA GCTCTTGAAC 1740 1741 TGCCTGCACG TGATCACCAT GTACAACCGC ATTAAGAAAG ACCCTAAGAA GTTGTTCGTG 1800 1801 CCAAGGACGG TCATAATCGG TGGCAAAGCT GCTCCCGGAT ATCACATGGC CAAAATGATC 1860 1861 ATAAAGCTGA TTACGTCAGT GGCACACGTG GTGAACAATG ACCCCGTGGT TGGAAGCAAG 1920 1921 TTGAAAGTCA TCTTCTTGGA GAACTACAGA GTGTCTCTCG CAGAAAAAGT CATTCCAGCC 1980 1981 ACAGATCTGT CAGAGCAGAT ATCCACTGCA GGCACCGAAG CCTCTGGAAC AGGAAATATG 2040 2041 AAGTTCATGC TGAACGGGGC CTTGACCATC GGGACCATGG ACGGAGCCAA CGTGGAAATG 2100 2101 GCAGAGGAAG CTGGGGAAGA GAACCTATTC ATCTTTGGCA TGAGGGTGGA GGATGTGGCT 2160 2161 GCTTTGGACA AGAAAGGGTA TGAGGCCAAA GAGTATTACG AGGCCCTTCC GGAACTGAAG 2220 2221 CTGGTCATTG ACCAAATCGA CAATGGCTTC TTCTCCCCTA AGCAGCCGGA CCTCTTCAAA 2280 2281 GACCTCGTGA ACATGCTGTT TCACCACGAC AGGTTTAAAG TCTTTGCAGA CTATGAAGCA 2340 2341 TATGTCAAGT GCCAAGAAAA AGTCAGCGAG CTGTACATGA ACCCAAAGGC CTGGAACACC 2400 2401 ATGGTACTCC GAAACATCGC TGCCTCGGGG AAATTCTCCA GCGACCGCAC CATTAAGGAG 2460 2461 TACGCCAGGG ACATCTGGGA CATGGAGCCT TCAGATCTCA AGATTTCCTT AGCCAGTGAA 2520 2521 CCTAGCAGTG GCCTGAACGC AGCTAATGGG AATTGA 2556 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | AMP binding | |
Molecular Function | ATP binding | |
Molecular Function | Bile acid binding | |
Molecular Function | Glycogen phosphorylase activity | |
Molecular Function | Linear malto-oligosaccharide phosphorylase activity | |
Molecular Function | Purine nucleobase binding | |
Molecular Function | Pyridoxal phosphate binding | |
Molecular Function | SHG alpha-glucan phosphorylase activity | |
Biological Process | Glucose homeostasis | |
Biological Process | Glycogen metabolic process | |
Biological Process | Necroptotic process | |
Biological Process | Response to bacterium |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a198 | Homo sapiens | 0.0 | 1429 | undefined |
| LLPS-Mum-a194 | Mus musculus | 0.0 | 1415 | undefined |