DrLLPS - Data resource of LLPS

LLPS-Orc-0309
RPS12

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	40S ribosomal protein S12
Gene Name:	RPS12
Ensembl Gene:	ENSOCUG00000001606.3
Ensembl Protein:	ENSOCUP00000001378.2
Organism:	Oryctolagus cuniculus
Taxa ID:	9986
LLPS Type:	LLPS regulator

PDB: 4D61 (1, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, 1 1-1742 GB X03205.1 1 1742, A 1-295 UNP P08865 1 295, B 1- 264 UNP P61247 1 264, C 1-293 UNP P15880 1 293, D 1-243 UNP P23396 1 243, E 1-263 UNP P22090 1 263, F 1-204 UNP P46782 1 204, G 1-249 UNP P62753 1 249, H 1-194 UNP P62081 1 194, I 1-208 UNP P62241 1 208, J 1-194 UNP P46781 1 194, K 1-165 UNP P46783 1 165, L 1-158 UNP P62280 1 158, M 1-132 UNP P25398 1 132, N 1-151 UNP P62277 1 151, O 1-151 UNP P62263 1 151, P 1-145 UNP P62841 1 145, Q 1-146 UNP P62249 1 146, R 1-135 UNP P08708 1 135, S 1-152 UNP P62269 1 152, T 1-145 UNP P39019 1 145, U 1-119 UNP P60866 1 119, V 1- 83 UNP P63220 1 83, W 1-130 UNP P62244 1 130, X 1-143 UNP P62266 1 143, Y 1-133 UNP P62847 1 133, Z 1-125 UNP P62851 1 125, A 1-115 UNP P62854 1 115, B 1-84 UNP P42677 1 84, C 1-69 UNP P62857 1 69, D 1-56 UNP P62273 1 56, E 1-59 UNP P62861 1 59, F 1-156 UNP P62979 1 156, G 1-317 UNP P63244 1 317) More

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nuclear speckle, Nucleolus, P-body, Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Caenorhabditis elegans	LLPS-Cae-0119	P49196	Regulator	P-body	65.05	1e-41	141
Mus musculus	LLPS-Mum-0360	P63323	Client	Nuclear speckle, Nucleolus	100.00	2e-90	265
Homo sapiens	LLPS-Hos-0064	P25398	Client	Nucleolus	100.00	2e-90	265
Saccharomyces cerevisiae	LLPS-Sac-0046	P48589	Client	Stress granule	54.70	2e-28	107

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSOCUT00000001606.3	ENSOCUP00000001378.2
UniProt		G1SFR8, G1SFR8_RABIT
GeneBank	AAGW02028778
RefSeq	XM_002714829.3	XP_002714875.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC VLASNCDEPM 60 61 YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP RKVVGCSCVV VKDYGKESQA 120 121 KDVIEEYFKC KK 132
Nucleotide CDS Sequence (FASTA)
1 ATGGCCGAGG AAGGCATTGC TGCTGGAGGT GTAATGGACG TTAACACTGC TCTACAAGAG 60 61 GTGCTGAAGA CCGCCCTCAT CCATGATGGC CTAGCCCGTG GAATCCGTGA AGCTGCCAAA 120 121 GCCTTAGACA AGCGCCAAGC CCATCTTTGT GTGCTTGCAT CTAACTGCGA TGAGCCTATG 180 181 TATGTCAAGC TGGTGGAGGC CCTGTGTGCT GAGCACCAAA TCAACCTCAT TAAGGTTGAT 240 241 GACAACAAGA AACTTGGGGA ATGGGTAGGC CTCTGTAAAA TTGACCGAGA AGGGAAACCC 300 301 CGCAAAGTGG TTGGTTGCAG TTGCGTAGTG GTTAAGGACT ACGGCAAAGA ATCTCAGGCC 360 361 AAGGATGTCA TCGAAGAATA CTTCAAATGC AAGAAATGA 399

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Fud-0436	Fukomys damarensis	100.0	2e-90	265
LLPS-Chs-0674	Chlorocebus sabaeus	100.0	1e-82	245
LLPS-Ora-0068	Ornithorhynchus anatinus	100.0	2e-90	265
LLPS-Mea-0235	Mesocricetus auratus	100.0	2e-90	265
LLPS-Maf-1383	Macaca fascicularis	100.0	2e-90	265
LLPS-Mum-0360	Mus musculus	100.0	2e-90	265
LLPS-Cea-0663	Cercocebus atys	100.0	2e-90	265
LLPS-Sah-1660	Sarcophilus harrisii	100.0	2e-90	265
LLPS-Aon-0044	Aotus nancymaae	100.0	2e-90	265
LLPS-Sus-0371	Sus scrofa	100.0	2e-90	265
LLPS-Ran-1571	Rattus norvegicus	100.0	2e-90	265
LLPS-Mup-2835	Mustela putorius furo	100.0	2e-90	265
LLPS-Aim-0075	Ailuropoda melanoleuca	100.0	2e-90	265
LLPS-Myl-0096	Myotis lucifugus	100.0	2e-90	265
LLPS-Ova-0221	Ovis aries	100.0	2e-90	265
LLPS-Paa-3132	Papio anubis	100.0	2e-90	265
LLPS-Tut-0008	Tursiops truncatus	100.0	2e-90	265
LLPS-Bot-1605	Bos taurus	100.0	8e-71	219
LLPS-Otg-1498	Otolemur garnettii	100.0	2e-90	265
LLPS-Rhb-1040	Rhinopithecus bieti	100.0	2e-90	265
LLPS-Mod-1271	Monodelphis domestica	100.0	2e-90	265
LLPS-Fec-0346	Felis catus	100.0	2e-90	265
LLPS-Pat-0102	Pan troglodytes	100.0	2e-90	265
LLPS-Pap-0623	Pan paniscus	100.0	2e-90	265
LLPS-Hos-0064	Homo sapiens	100.0	2e-90	265
LLPS-Loa-0689	Loxodonta africana	100.0	2e-90	265
LLPS-Man-0448	Macaca nemestrina	100.0	2e-90	265
LLPS-Cas-0387	Carlito syrichta	100.0	2e-90	265
LLPS-Nol-0502	Nomascus leucogenys	100.0	2e-90	265
LLPS-Cap-0446	Cavia porcellus	100.0	2e-90	265
LLPS-Poa-0773	Pongo abelii	100.0	2e-90	265
LLPS-Caf-3089	Canis familiaris	100.0	2e-90	265
LLPS-Mam-0291	Macaca mulatta	100.0	2e-90	265
LLPS-Gog-1036	Gorilla gorilla	99.24	7e-90	263
LLPS-Dio-1620	Dipodomys ordii	99.24	5e-90	264
LLPS-Gaga-0845	Gallus gallus	99.24	5e-90	264
LLPS-Mal-0844	Mandrillus leucophaeus	99.22	1e-86	256
LLPS-Fia-0660	Ficedula albicollis	99.17	1e-81	243
LLPS-Caj-1188	Callithrix jacchus	98.51	1e-88	260
LLPS-Tag-0579	Taeniopygia guttata	98.48	3e-89	262
LLPS-Meg-0461	Meleagris gallopavo	98.45	3e-86	254
LLPS-Leo-1180	Lepisosteus oculatus	97.73	2e-88	260
LLPS-Anc-1063	Anolis carolinensis	97.73	4e-89	262
LLPS-Scm-1320	Scophthalmus maximus	97.35	5e-73	223
LLPS-Icp-0711	Ictalurus punctatus	97.3	7e-72	219
LLPS-Asm-0935	Astyanax mexicanus	96.97	7e-88	258
LLPS-Orl-0457	Oryzias latipes	96.97	9e-87	256
LLPS-Pof-0612	Poecilia formosa	96.97	7e-88	259
LLPS-Dar-0040	Danio rerio	96.97	7e-88	258
LLPS-Anp-0542	Anas platyrhynchos	96.97	3e-87	257
LLPS-Pes-0299	Pelodiscus sinensis	96.95	1e-86	255
LLPS-Orn-2117	Oreochromis niloticus	96.63	1e-56	177
LLPS-Tar-2549	Takifugu rubripes	96.21	2e-87	259
LLPS-Ten-1343	Tetraodon nigroviridis	96.21	3e-87	257
LLPS-Urm-1037	Ursus maritimus	95.49	2e-84	251
LLPS-Ere-0004	Erinaceus europaeus	95.45	6e-87	256
LLPS-Xim-1255	Xiphophorus maculatus	95.06	9e-48	157
LLPS-Lac-0820	Latimeria chalumnae	94.7	3e-85	252
LLPS-Scf-0410	Scleropages formosus	93.18	1e-84	250
LLPS-Gaa-0634	Gasterosteus aculeatus	92.54	3e-83	247
LLPS-Xet-2774	Xenopus tropicalis	89.92	3e-78	234
LLPS-Eqc-0387	Equus caballus	84.3	3e-68	208
LLPS-Ict-0394	Ictidomys tridecemlineatus	78.79	4e-60	187
LLPS-Cii-0343	Ciona intestinalis	76.61	1e-64	199
LLPS-Cis-0910	Ciona savignyi	76.61	3e-64	199
LLPS-Miv-0022	Microbotryum violaceum	71.2	2e-57	182
LLPS-Usm-0146	Ustilago maydis	70.4	5e-59	186
LLPS-Spr-0283	Sporisorium reilianum	70.4	5e-59	186
LLPS-Mel-0107	Melampsora laricipopulina	69.11	4e-46	153
LLPS-Pug-0887	Puccinia graminis	69.11	3e-45	152
LLPS-Abg-1052	Absidia glauca	68.8	4e-56	178
LLPS-Scc-0865	Schizosaccharomyces cryophilus	67.8	4e-47	156
LLPS-Drm-0752	Drosophila melanogaster	67.5	4e-52	168
LLPS-Scj-0765	Schizosaccharomyces japonicus	66.1	5e-49	160
LLPS-Nef-0111	Neosartorya fischeri	65.87	1e-52	169
LLPS-Asfu-0427	Aspergillus fumigatus	65.87	1e-52	169
LLPS-Lem-0319	Leptosphaeria maculans	65.85	2e-52	169
LLPS-Phn-1015	Phaeosphaeria nodorum	65.85	2e-52	170
LLPS-Tum-0634	Tuber melanosporum	65.83	2e-51	166
LLPS-Beb-0338	Beauveria bassiana	65.6	2e-52	169
LLPS-Scp-0627	Schizosaccharomyces pombe	65.55	9e-48	157
LLPS-Aso-0291	Aspergillus oryzae	65.29	3e-50	162
LLPS-Asni-0722	Aspergillus niger	65.08	2e-52	169
LLPS-Asc-0251	Aspergillus clavatus	65.08	2e-52	169
LLPS-Asf-0671	Aspergillus flavus	65.08	3e-52	169
LLPS-Ast-0092	Aspergillus terreus	65.08	2e-52	169
LLPS-Dos-0526	Dothistroma septosporum	65.08	2e-52	169
LLPS-Pyt-0077	Pyrenophora teres	65.04	2e-50	175
LLPS-Pytr-0014	Pyrenophora triticirepentis	65.04	6e-52	167
LLPS-Crn-0943	Cryptococcus neoformans	64.8	7e-53	170
LLPS-Cym-0361	Cyanidioschyzon merolae	64.71	9e-41	139
LLPS-Sem-1721	Selaginella moellendorffii	64.46	3e-50	163
LLPS-Zyt-0182	Zymoseptoria tritici	64.46	1e-49	161
LLPS-Mao-0091	Magnaporthe oryzae	64.29	8e-51	165
LLPS-Gag-0449	Gaeumannomyces graminis	64.29	7e-51	165
LLPS-Trr-0158	Trichoderma reesei	64.06	4e-51	166
LLPS-Trv-0018	Trichoderma virens	64.06	4e-51	166
LLPS-Brd-2151	Brachypodium distachyon	63.64	1e-50	164
LLPS-Sei-0416	Setaria italica	63.64	6e-50	162
LLPS-Sob-0017	Sorghum bicolor	63.64	8e-50	162
LLPS-Zem-0497	Zea mays	63.64	6e-50	162
LLPS-Php-2207	Physcomitrella patens	63.49	3e-51	166
LLPS-Map-0528	Magnaporthe poae	63.49	4e-49	160
LLPS-Coo-0566	Colletotrichum orbiculare	63.41	1e-49	162
LLPS-Cog-1036	Colletotrichum gloeosporioides	63.41	1e-49	162
LLPS-Cogr-0288	Colletotrichum graminicola	63.41	2e-49	161
LLPS-Orni-0304	Oryza nivara	63.03	5e-49	160
LLPS-Ori-0125	Oryza indica	62.81	1e-49	161
LLPS-Orb-1031	Oryza barthii	62.81	1e-49	161
LLPS-Tra-0131	Triticum aestivum	62.81	7e-50	162
LLPS-Orgl-0273	Oryza glumaepatula	62.81	1e-49	161
LLPS-Orbr-1529	Oryza brachyantha	62.81	1e-49	162
LLPS-Ors-0156	Oryza sativa	62.81	1e-49	161
LLPS-Orp-0756	Oryza punctata	62.81	1e-49	161
LLPS-Tru-0730	Triticum urartu	62.81	8e-50	162
LLPS-Org-0801	Oryza glaberrima	62.81	1e-49	161
LLPS-Orr-0256	Oryza rufipogon	62.81	1e-49	161
LLPS-Orm-0886	Oryza meridionalis	62.81	4e-49	162
LLPS-Scs-0102	Sclerotinia sclerotiorum	62.5	4e-50	163
LLPS-Hov-1410	Hordeum vulgare	61.98	2e-48	160
LLPS-Lep-0457	Leersia perrieri	61.98	3e-49	160
LLPS-Fus-0436	Fusarium solani	61.98	5e-49	159
LLPS-Mua-1513	Musa acuminata	61.86	2e-47	155
LLPS-Put-0514	Puccinia triticina	61.83	2e-38	133
LLPS-Amt-1538	Amborella trichopoda	61.48	6e-47	165
LLPS-Cae-0119	Caenorhabditis elegans	61.29	3e-46	153
LLPS-Ved-0013	Verticillium dahliae	61.07	3e-49	160
LLPS-Viv-0688	Vitis vinifera	60.98	7e-47	157
LLPS-Dac-1175	Daucus carota	60.33	2e-46	153
LLPS-Vir-0529	Vigna radiata	60.17	2e-45	150
LLPS-Pot-0430	Populus trichocarpa	60.17	1e-45	151
LLPS-Fuv-0064	Fusarium verticillioides	60.16	1e-49	162
LLPS-Nia-0217	Nicotiana attenuata	60.16	7e-38	131
LLPS-Fuo-1005	Fusarium oxysporum	60.16	1e-49	162
LLPS-Glm-1303	Glycine max	59.5	1e-45	151
LLPS-Via-0798	Vigna angularis	59.5	2e-45	150
LLPS-Phv-1617	Phaseolus vulgaris	59.5	8e-46	152
LLPS-Prp-1419	Prunus persica	59.5	5e-44	148
LLPS-Hea-2385	Helianthus annuus	59.35	6e-46	152
LLPS-Sol-0607	Solanum lycopersicum	59.35	3e-37	130
LLPS-Sot-1582	Solanum tuberosum	59.35	3e-37	130
LLPS-Blg-0690	Blumeria graminis	59.35	8e-47	154
LLPS-Cus-1629	Cucumis sativus	58.82	2e-44	148
LLPS-Nec-1111	Neurospora crassa	58.73	4e-47	155
LLPS-Chr-0324	Chlamydomonas reinhardtii	58.14	1e-50	164
LLPS-Gor-0645	Gossypium raimondii	57.98	4e-45	150
LLPS-Met-0557	Medicago truncatula	57.85	3e-44	147
LLPS-Thc-1832	Theobroma cacao	57.6	2e-46	153
LLPS-Chc-0062	Chondrus crispus	57.5	4e-45	150
LLPS-Mae-1872	Manihot esculenta	57.02	1e-44	149
LLPS-Coc-0001	Corchorus capsularis	56.8	3e-46	153
LLPS-Brn-2077	Brassica napus	56.78	4e-43	144
LLPS-Brr-0758	Brassica rapa	56.78	5e-43	145
LLPS-Bro-0521	Brassica oleracea	56.78	5e-43	145
LLPS-Gas-0622	Galdieria sulphuraria	56.64	7e-41	139
LLPS-Arl-0321	Arabidopsis lyrata	55.56	2e-41	140
LLPS-Kop-0436	Komagataella pastoris	53.33	3e-38	132
LLPS-Art-0233	Arabidopsis thaliana	52.99	1e-40	139
LLPS-Yal-0474	Yarrowia lipolytica	52.54	5e-36	127
LLPS-Osl-0315	Ostreococcus lucimarinus	52.54	1e-38	133
LLPS-Asn-0429	Aspergillus nidulans	52.44	3e-46	154

LLPS-Orc-0309RPS12

Protein Sequence

Nucleotide Sequence

LLPS-Orc-0309
RPS12