• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ora-3205
DTL

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Denticleless E3 ubiquitin protein ligase homolog
Gene Name: DTL
Ensembl Gene: ENSOANG00000008486.2
Ensembl Protein: ENSOANP00000013502.1
Organism: Ornithorhynchus anatinus
Taxa ID: 9258
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLFRSLLAQP  RQGGTSNGRF  SHYPLQSLLA  GYQCSYQDDH  LSYGEMGVPV  PPFGCTFSTA  60
61    PNLQHILAVA  NEEGFISLYN  TESRTCRKKF  FKEWMAHSNA  VFDLTWVPGE  HRLVTASGDQ  120
121   TARLWDVKAG  ELIGVCKGHQ  CSLKSVAFSK  FQKAVFCTGG  RDGNIMVWDT  RCNKKDGFYR  180
181   QVNQISGAHN  ISDKQTPLKF  KKKKLNVRGL  APSVDFQQSV  TVVVFQDEHT  LVSAGAVDGI  240
241   IKVWDLRKNY  TTHKQEPVSC  KSFSYPGNST  RKLGYSSLVM  DSTCSTLFAN  CTDDNIYMFN  300
301   MTGLQTTPVA  TFSGHQNSTF  YVKSSISPDD  QFLVSGSSDE  AAYIWKISEP  QHPPTLLLGH  360
361   SQEVTTVCWC  PSDFTKIATC  SDDNTMRVWR  LRRGSEEKLT  PGKMALVGWA  YQKKAEERAK  420
421   LEATTSSQST  PAKAPRVESS  PSVSSPRSAA  CAPNCTGDLP  LSSNTPTSSF  RTPPANTQTP  480
481   VRRRESISTS  SPKPPSSSKM  SIRNWVTRTP  YSTPPATKTK  TPSPRKILVP  VTQTLSQVVT  540
541   VPKAATPSGT  KAKRRLDSSC  PDSIEPKCLK  NCSCVMELDA  EVKKAKLDLC  CLAGNQGSGE  600
601   DCLSLTQLNG  LEGTSQGLQD  PSSPSSPLSP  EDFSSPTLPS  KSPRGTGTKV  TDKENSSPNW  660
661   LAAMGARWRT  EKAGSRSPSS  NSPSSSQTPN  ARRQDGKNSP  GPVPTTPVSM  RKICTYFHRK  720
721   SQDDYSSPEQ  SKEL  734
Nucleotide CDS Sequence (FASTA)
1     ATGCTCTTCC  GCTCGCTTCT  TGCCCAGCCC  CGGCAGGGCG  GCACCTCGAA  CGGACGGTTT  60
61    TCCCACTACC  CTCTCCAGTC  ACTTTTAGCT  GGCTACCAGT  GCAGTTACCA  AGATGATCAT  120
121   CTTTCTTATG  GAGAGATGGG  TGTTCCAGTC  CCTCCTTTCG  GATGCACCTT  TTCTACTGCC  180
181   CCCAACCTAC  AGCATATTCT  TGCAGTTGCC  AATGAAGAAG  GCTTCATTAG  CCTGTACAAC  240
241   ACAGAATCCC  GCACTTGCAG  AAAGAAATTT  TTCAAAGAGT  GGATGGCTCA  CTCCAACGCT  300
301   GTCTTTGACC  TGACTTGGGT  TCCTGGAGAA  CATCGACTTG  TGACAGCATC  AGGAGATCAG  360
361   ACAGCCAGAC  TGTGGGATGT  CAAAGCTGGA  GAGCTGATTG  GAGTATGCAA  AGGTCATCAG  420
421   TGCAGCCTCA  AGTCAGTTGC  CTTTTCTAAA  TTTCAGAAAG  CTGTATTTTG  TACCGGAGGA  480
481   AGAGATGGCA  ACATTATGGT  CTGGGACACC  AGATGCAACA  AGAAAGATGG  ATTTTACAGG  540
541   CAAGTGAATC  AAATCAGTGG  TGCTCACAAC  ATCTCAGATA  AGCAGACTCC  TCTGAAGTTT  600
601   AAGAAGAAGA  AGCTGAATGT  GAGAGGACTT  GCTCCTTCAG  TGGATTTTCA  GCAAAGTGTG  660
661   ACTGTGGTTG  TCTTTCAAGA  TGAGCACACC  CTAGTGTCAG  CAGGAGCTGT  GGATGGAATA  720
721   ATCAAAGTGT  GGGATTTGCG  GAAAAATTAC  ACCACCCATA  AGCAGGAGCC  AGTATCCTGC  780
781   AAGTCCTTCT  CATACCCGGG  TAACAGCACT  CGCAAACTAG  GATACTCAAG  TCTTGTTATG  840
841   GACTCCACTT  GTTCCACTCT  GTTTGCTAAC  TGCACAGATG  ATAATATCTA  CATGTTCAAT  900
901   ATGACAGGCT  TACAGACCAC  TCCAGTGGCA  ACCTTCAGTG  GACATCAGAA  CTCCACCTTT  960
961   TATGTGAAAT  CCAGTATTAG  CCCTGATGAT  CAATTCCTGG  TCAGTGGTTC  CAGTGATGAG  1020
1021  GCTGCTTATA  TCTGGAAGAT  CTCTGAGCCC  CAACATCCTC  CTACTTTGCT  CCTGGGCCAT  1080
1081  TCTCAAGAAG  TTACGACTGT  GTGTTGGTGT  CCTTCCGATT  TTACTAAGAT  TGCTACATGT  1140
1141  TCTGATGATA  ATACCATGAG  GGTTTGGCGC  CTGAGACGTG  GCAGTGAAGA  GAAGTTGACT  1200
1201  CCAGGCAAGA  TGGCCTTGGT  GGGTTGGGCC  TATCAGAAGA  AAGCAGAGGA  GAGAGCTAAA  1260
1261  TTGGAAGCAA  CAACAAGCAG  CCAGAGCACT  CCGGCCAAAG  CCCCCCGGGT  GGAGAGCAGC  1320
1321  CCGTCCGTTT  CCTCGCCGCG  GTCCGCAGCT  TGTGCTCCAA  ACTGTACTGG  GGACCTCCCT  1380
1381  CTCTCATCCA  ATACTCCCAC  ATCCAGCTTC  AGAACTCCCC  CTGCCAATAC  CCAGACTCCA  1440
1441  GTCCGTAGAA  GGGAGTCCAT  CTCCACCTCT  TCTCCCAAGC  CACCTTCCTC  CTCCAAGATG  1500
1501  TCAATTAGAA  ATTGGGTGAC  CCGGACTCCT  TACTCAACCC  CACCTGCGAC  TAAAACCAAG  1560
1561  ACACCATCTC  CCAGAAAAAT  CCTCGTCCCT  GTGACCCAGA  CTCTGTCCCA  GGTGGTGACC  1620
1621  GTCCCCAAGG  CAGCCACTCC  ATCTGGAACA  AAAGCTAAGA  GGCGGTTGGA  CTCAAGCTGT  1680
1681  CCGGACAGCA  TTGAGCCAAA  GTGTTTAAAA  AATTGCAGTT  GTGTGATGGA  GCTTGATGCT  1740
1741  GAGGTTAAGA  AAGCCAAGCT  AGATCTGTGT  TGCCTGGCAG  GGAACCAAGG  CAGTGGTGAG  1800
1801  GACTGTCTGA  GCCTCACTCA  ATTAAACGGA  CTTGAAGGGA  CCAGCCAGGG  TTTGCAGGAT  1860
1861  CCTTCCTCTC  CTTCTAGTCC  CCTTTCCCCA  GAAGACTTTA  GTTCACCCAC  TCTTCCTTCC  1920
1921  AAATCACCTC  GTGGAACAGG  GACCAAAGTG  ACAGACAAGG  AAAATAGTTC  CCCCAATTGG  1980
1981  CTGGCTGCCA  TGGGAGCAAG  ATGGCGAACT  GAGAAAGCTG  GAAGCCGCAG  TCCATCTTCC  2040
2041  AACAGTCCTT  CCTCCTCTCA  GACCCCTAAT  GCTAGACGGC  AGGATGGGAA  GAATTCGCCA  2100
2101  GGACCTGTTC  CAACTACTCC  AGTTTCCATG  AGGAAGATCT  GTACTTACTT  CCACCGAAAG  2160
2161  TCCCAGGATG  ACTATAGTAG  CCCTGAGCAG  TCAAAAGAAT  TGTAG  2205

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-3027Monodelphis domestica73.320.0 971
LLPS-Mea-2324Mesocricetus auratus72.574e-50 176
LLPS-Sah-2579Sarcophilus harrisii71.990.0 931
LLPS-Eqc-2690Equus caballus70.220.0 918
LLPS-Aim-3123Ailuropoda melanoleuca70.080.0 917
LLPS-Urm-0574Ursus maritimus70.080.0 908
LLPS-Caj-3342Callithrix jacchus69.810.0 920
LLPS-Aon-4601Aotus nancymaae69.810.0 920
LLPS-Otg-4242Otolemur garnettii69.810.0 930
LLPS-Cas-3264Carlito syrichta69.720.0 915
LLPS-Mup-0174Mustela putorius furo69.680.0 910
LLPS-Orc-3485Oryctolagus cuniculus69.680.0 922
LLPS-Fec-0474Felis catus69.680.0 909
LLPS-Caf-1982Canis familiaris69.680.0 912
LLPS-Sus-3580Sus scrofa69.520.0 879
LLPS-Ict-1753Ictidomys tridecemlineatus69.40.0 914
LLPS-Fud-1172Fukomys damarensis69.140.0 920
LLPS-Maf-1239Macaca fascicularis69.140.0 913
LLPS-Chs-1046Chlorocebus sabaeus69.140.0 914
LLPS-Cea-4409Cercocebus atys69.140.0 914
LLPS-Mal-4462Mandrillus leucophaeus69.140.0 914
LLPS-Paa-3462Papio anubis69.140.0 914
LLPS-Ova-1522Ovis aries69.140.0 915
LLPS-Rhb-0321Rhinopithecus bieti69.140.0 914
LLPS-Man-3478Macaca nemestrina69.140.0 913
LLPS-Mam-2755Macaca mulatta69.140.0 913
LLPS-Bot-3979Bos taurus69.00.0 901
LLPS-Pat-2816Pan troglodytes68.870.0 907
LLPS-Loa-0149Loxodonta africana68.820.0 899
LLPS-Hos-1116Homo sapiens68.730.0 906
LLPS-Gog-2623Gorilla gorilla68.60.0 903
LLPS-Dio-0071Dipodomys ordii68.560.0 904
LLPS-Myl-1920Myotis lucifugus68.190.0 883
LLPS-Cap-1251Cavia porcellus67.160.0 908
LLPS-Mum-3065Mus musculus66.890.0 879
LLPS-Pap-0271Pan paniscus66.760.0 828
LLPS-Nol-4180Nomascus leucogenys66.210.0 825
LLPS-Ran-1824Rattus norvegicus65.630.0 863
LLPS-Pes-1003Pelodiscus sinensis65.260.0 761
LLPS-Anp-3064Anas platyrhynchos64.020.0 802
LLPS-Scf-2297Scleropages formosus63.70.0 577
LLPS-Icp-2353Ictalurus punctatus63.20.0 556
LLPS-Fia-2222Ficedula albicollis62.870.0 788
LLPS-Tag-1786Taeniopygia guttata62.830.0 789
LLPS-Meg-3016Meleagris gallopavo61.880.0 789
LLPS-Gaga-1874Gallus gallus61.80.0 787
LLPS-Orn-2964Oreochromis niloticus60.820.0 548
LLPS-Xim-3983Xiphophorus maculatus60.680.0 547
LLPS-Tar-3473Takifugu rubripes60.360.0 555
LLPS-Ten-3411Tetraodon nigroviridis59.770.0 542
LLPS-Pof-3799Poecilia formosa59.351e-169 510
LLPS-Xet-2522Xenopus tropicalis57.420.0 739
LLPS-Anc-2074Anolis carolinensis57.20.0 730
LLPS-Lac-1118Latimeria chalumnae54.70.0 665
LLPS-Poa-1441Pongo abelii54.040.0 603
LLPS-Leo-3240Lepisosteus oculatus51.510.0 633
LLPS-Asm-2806Astyanax mexicanus49.320.0 561
LLPS-Orl-0302Oryzias latipes46.880.0 565
LLPS-Scm-3841Scophthalmus maximus45.550.0 578
LLPS-Dar-3410Danio rerio45.260.0 542
LLPS-Gaa-3248Gasterosteus aculeatus45.160.0 571
LLPS-Ors-0165Oryza sativa44.191e-1891.3
LLPS-Drm-2385Drosophila melanogaster40.316e-83 286
LLPS-Php-1410Physcomitrella patens38.428e-69 240
LLPS-Mae-2176Manihot esculenta36.82e-63 226
LLPS-Cus-1004Cucumis sativus36.514e-67 236
LLPS-Art-1953Arabidopsis thaliana36.392e-65 232
LLPS-Brn-0381Brassica napus36.211e-63 227
LLPS-Arl-1369Arabidopsis lyrata35.931e-63 227
LLPS-Nia-0746Nicotiana attenuata35.854e-62 222
LLPS-Pot-1253Populus trichocarpa35.693e-64 228
LLPS-Viv-0699Vitis vinifera35.659e-63 224
LLPS-Brr-2561Brassica rapa35.659e-64 227
LLPS-Coc-2207Corchorus capsularis35.614e-64 228
LLPS-Dac-0252Daucus carota35.536e-67 236
LLPS-Amt-0194Amborella trichopoda35.453e-67 239
LLPS-Gor-2252Gossypium raimondii35.394e-64 228
LLPS-Sol-0387Solanum lycopersicum35.086e-61 219
LLPS-Bro-3004Brassica oleracea34.821e-60 218
LLPS-Thc-2015Theobroma cacao34.521e-63 226
LLPS-Sot-0681Solanum tuberosum34.453e-57 209
LLPS-Vir-1380Vigna radiata34.422e-63 226
LLPS-Via-0817Vigna angularis34.332e-63 226
LLPS-Phv-2157Phaseolus vulgaris34.323e-65 231
LLPS-Prp-2224Prunus persica34.296e-58 211
LLPS-Hea-2329Helianthus annuus34.164e-61 219
LLPS-Glm-0260Glycine max33.995e-61 219
LLPS-Met-1913Medicago truncatula33.785e-62 222
LLPS-Mua-0594Musa acuminata33.426e-60 216
LLPS-Hov-1069Hordeum vulgare33.069e-64 229
LLPS-Orp-1366Oryza punctata31.897e-57 208
LLPS-Sei-1055Setaria italica31.738e-60 216
LLPS-Sob-1292Sorghum bicolor31.732e-61 220
LLPS-Brd-2175Brachypodium distachyon31.456e-64 228
LLPS-Orni-0616Oryza nivara31.183e-57 209
LLPS-Ori-2158Oryza indica31.183e-57 209
LLPS-Org-0974Oryza glaberrima31.184e-57 208
LLPS-Lep-0274Leersia perrieri30.942e-58 212
LLPS-Miv-1240Microbotryum violaceum30.673e-42 167
LLPS-Orb-1511Oryza barthii30.661e-56 208
LLPS-Orm-1801Oryza meridionalis30.623e-56 206
LLPS-Tru-0606Triticum urartu30.512e-45 172
LLPS-Put-0727Puccinia triticina30.453e-1686.3
LLPS-Zem-0695Zea mays30.313e-59 215
LLPS-Tra-2321Triticum aestivum30.33e-62 223
LLPS-Orr-2442Oryza rufipogon30.086e-57 209
LLPS-Pug-0655Puccinia graminis30.075e-2098.6
LLPS-Orgl-1773Oryza glumaepatula30.064e-48 182
LLPS-Gas-0933Galdieria sulphuraria29.952e-46 177
LLPS-Abg-0395Absidia glauca29.853e-46 176
LLPS-Scj-0510Schizosaccharomyces japonicus29.21e-29 127
LLPS-Chr-1740Chlamydomonas reinhardtii28.611e-41 168
LLPS-Scs-1111Sclerotinia sclerotiorum27.851e-20 101
LLPS-Osl-0753Ostreococcus lucimarinus27.531e-31 132
LLPS-Nec-0831Neurospora crassa27.239e-25 114
LLPS-Trv-0651Trichoderma virens27.171e-21 104
LLPS-Scc-1416Schizosaccharomyces cryophilus27.15e-25 113
LLPS-Mel-0971Melampsora laricipopulina26.749e-22 104
LLPS-Blg-0189Blumeria graminis26.682e-25 116
LLPS-Phn-1394Phaeosphaeria nodorum26.612e-28 125
LLPS-Trr-1024Trichoderma reesei26.32e-21 103
LLPS-Crn-1298Cryptococcus neoformans26.181e-25 117
LLPS-Cae-0782Caenorhabditis elegans26.043e-30 131
LLPS-Lem-0282Leptosphaeria maculans25.912e-25 115
LLPS-Tum-1168Tuber melanosporum25.781e-1995.9
LLPS-Orbr-0998Oryza brachyantha25.742e-1684.7
LLPS-Ast-1261Aspergillus terreus25.644e-1685.5
LLPS-Scp-1535Schizosaccharomyces pombe25.582e-2099.8
LLPS-Zyt-0336Zymoseptoria tritici25.443e-25 114
LLPS-Pyt-0908Pyrenophora teres25.271e-25 116
LLPS-Asfu-1118Aspergillus fumigatus25.162e-20 100
LLPS-Asn-1405Aspergillus nidulans25.12e-1997.4
LLPS-Nef-1550Neosartorya fischeri24.959e-21 101
LLPS-Pytr-1360Pyrenophora triticirepentis24.784e-25 115
LLPS-Cogr-0677Colletotrichum graminicola24.64e-2099.8
LLPS-Asc-1271Aspergillus clavatus24.543e-2099.8
LLPS-Beb-1550Beauveria bassiana24.366e-1789.4
LLPS-Aso-0136Aspergillus oryzae23.72e-1894.4
LLPS-Dos-1479Dothistroma septosporum23.687e-25 114
LLPS-Asni-1601Aspergillus niger23.572e-1893.6
LLPS-Ved-1187Verticillium dahliae22.986e-1995.9