LLPS-Ora-1997
TRPM3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Transient receptor potential cation channel subfamily M member 3 |
| Gene Name: | TRPM3 |
| Ensembl Gene: | ENSOANG00000005022.3 |
| Ensembl Protein: | ENSOANP00000007966.2 |
| Organism: | Ornithorhynchus anatinus |
| Taxa ID: | 9258 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOANT00000007968.2 | ENSOANP00000007966.2 |
| UniProt | F7FZ96, F7FZ96_ORNAN | |
| GeneBank | AAPN01357219, AAPN01357222, AAPN01357224, AAPN01357226, AAPN01357227, AAPN01357221, AAPN01357218, AAPN01357225, AAPN01357220, AAPN01357223 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MNPNDAHRPL NWTIRKLCHA AFLPSVRLLK AQKSWIERAF YKRECVHIIP STKDPHRCCC 60 61 GRLIGQHVGL TPSISVIQNE KNESRLSRND VQSEKWSISK HTQLSPTDAF GTIEFQGGGH 120 121 SNKAMYVRVS YDTKPDLLLH LLTKEWQLEL PKLLISVHGG LQNFELQPKL KQVFGKGLIK 180 181 AAMTTGAWIF TGGVNTGVIR HVGDALKDHA SKSRGKICTI GIAPWGIVEN QEDLIGKDVV 240 241 RPYQTMSNPM SKLTVLNSMH SHFILADNGT TGKYGAEVKL RRQLEKHISL QKINTRIGQG 300 301 VPVVALIVEG GPNVISIVLE YLRDTPPVPV VVCDGSGRAS DILAFGHKYS EEGGLINESL 360 361 RDQLLVTIQK TFTYTRTQAQ HLFIILMECM KKKELITVFR MGSEGHQDID LAILTALLKG 420 421 ANASAPDQLS LALAWNRVDI ARSQIFIYGQ QWPVGSLEQA MLDALVLDRV DFVKLLIENG 480 481 VSMHRFLTIS RLEELYNTRH GPSNTLYHLV RDVKKREYPG FGWIYFKGNL PPDYRISLID 540 541 IGLVIEYLMG GAYRCNYTRK RFRTLYHNLF GPKRPKALKL LGMEDDVPLR RGRKTTKKRE 600 601 EEVDIDLDDP EINHFPFPFH ELMVWAVLMK RQKMALFFWQ HGEEAMAKAL VACKLCKAMA 660 661 HEASENDMVD DISQELNHNS RLIYFCNKAR KLWQSFLRDA KRNWHHLTIE MDNWTKSQTP 720 721 GPSLQFILSA ATWIVFLEHS CPQVPTLLNP LLASHVNQER SETGTELVES LPLKPHIIAI 780 781 GPSDPDKKPW LVLAFELLCL RRSWENKTQK HLTPENNEKT AMLGRNNGES SRKKDEEEVH 840 841 SRHRLIPLGR KIYEFYNAPI VKFWFYTLAY IGYLMLFNYI VLVKMDRWPS VQEWIVISYI 900 901 FTLGIEKMRE ILMSEPGKLL QKVKVWLQEY WNVTDLIAIL LFSIGMILRL QDQPFRSDGR 960 961 VIYCVNIIYW YIRLLDIFGV NKYLGPYVMM IGKMMIDMMY FVIIMLVVLM SFGVARQAIL 1020 1021 FPNEEPSWKL AKNIFYMPYW MIYGEVFADQ IDPPCGQNET REDGKIIQLP PCKTGAWIVP 1080 1081 AIMACYLLVA NILLVNLLIA VFNNTFFEVK SISNQVWKFQ RYQLIMTFHE RPVLPPPLII 1140 1141 FSHMTMIFQH LCCRWRKHES DPDERDYGLK LFITDDELKK VHDFEEQCIE EYFREKDDRF 1200 1201 NSSNDERIRV TSERVENMSM RLEEVNEREH CMKASLQTVD IRLAQLEDLI GRMATAMERL 1260 1261 TGLERAESNK IRSRTSSDCT DTAYIVRQSS FNSQEGNAYK LQESIDPAEH PFYSV 1315 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAATCCTA ATGATGCTCA CCGACCACTA AACTGGACCA TTAGAAAGCT GTGCCATGCT 60 61 GCCTTTCTCC CATCTGTCAG ACTTCTCAAG GCTCAAAAGT CCTGGATAGA AAGAGCATTT 120 121 TACAAGAGAG AATGTGTTCA CATCATACCC AGCACTAAAG ATCCTCATAG GTGTTGCTGT 180 181 GGCCGTCTAA TCGGTCAGCA TGTTGGGCTG ACCCCAAGTA TCTCGGTGAT TCAGAATGAG 240 241 AAAAATGAAA GTCGACTCTC TCGGAATGAT GTCCAGTCTG AGAAGTGGTC CATCAGCAAG 300 301 CACACTCAAC TTAGCCCGAC TGATGCCTTT GGAACAATTG AGTTCCAGGG TGGTGGCCAC 360 361 TCCAACAAAG CGATGTACGT GCGTGTGTCC TATGACACAA AGCCTGATCT TCTTCTACAC 420 421 CTGCTGACTA AGGAGTGGCA GTTAGAGCTC CCCAAGCTGC TCATCTCGGT TCATGGAGGC 480 481 CTCCAGAACT TCGAACTCCA GCCAAAACTC AAGCAAGTCT TTGGGAAAGG CCTAATCAAA 540 541 GCTGCCATGA CAACTGGAGC GTGGATATTC ACTGGAGGAG TCAACACAGG AGTCATTCGG 600 601 CATGTTGGAG ATGCATTGAA GGATCACGCC TCAAAATCAC GAGGGAAGAT ATGCACCATA 660 661 GGAATTGCCC CCTGGGGGAT TGTGGAAAAC CAGGAGGATC TGATTGGGAA AGATGTTGTC 720 721 CGTCCATACC AGACCATGTC CAATCCTATG AGTAAACTCA CTGTACTCAA CAGTATGCAT 780 781 TCCCACTTCA TTCTGGCTGA CAATGGGACC ACAGGAAAAT ATGGAGCAGA AGTGAAACTG 840 841 AGAAGACAGC TGGAAAAGCA TATCTCACTG CAGAAGATAA ACACAAGAAT TGGCCAAGGA 900 901 GTTCCTGTCG TGGCCCTCAT TGTGGAAGGT GGACCAAATG TAATCTCCAT TGTTCTGGAG 960 961 TACCTTAGAG ACACTCCACC AGTTCCTGTG GTGGTCTGTG ATGGGAGTGG ACGGGCATCT 1020 1021 GACATCCTTG CTTTTGGACA TAAATATTCT GAAGAAGGAG GTCTCATTAA TGAATCTTTG 1080 1081 AGGGACCAAT TGCTAGTTAC AATCCAGAAG ACTTTCACCT ACACTCGAAC CCAGGCCCAG 1140 1141 CATCTTTTCA TAATCCTCAT GGAGTGCATG AAGAAGAAGG AATTGATTAC GGTATTTCGG 1200 1201 ATGGGATCGG AAGGACACCA GGACATTGAT TTAGCTATCC TGACAGCTTT GCTCAAAGGA 1260 1261 GCTAATGCCT CTGCTCCGGA CCAATTGAGC CTGGCATTAG CCTGGAACAG GGTAGACATC 1320 1321 GCTCGCAGTC AGATCTTTAT TTATGGGCAA CAGTGGCCGG TGGGGTCCCT GGAGCAAGCG 1380 1381 ATGTTGGATG CTCTGGTGTT GGACAGAGTG GATTTTGTGA AATTACTCAT AGAGAATGGA 1440 1441 GTAAGCATGC ATCGTTTTCT CACCATCTCC AGGCTAGAGG AACTGTACAA TACGAGACAT 1500 1501 GGGCCATCCA ACACTCTGTA CCACCTGGTC AGGGATGTCA AAAAGCGAGA ATATCCAGGT 1560 1561 TTCGGTTGGA TCTATTTTAA GGGGAACCTG CCTCCGGATT ACAGGATAAG CTTGATCGAC 1620 1621 ATTGGGCTGG TGATTGAGTA CCTGATGGGA GGAGCTTATC GCTGCAACTA CACTCGAAAG 1680 1681 CGATTCAGAA CCCTCTACCA CAACCTGTTT GGACCTAAGA GGCCAAAAGC CTTGAAACTG 1740 1741 CTGGGAATGG AGGATGATGT TCCCCTGAGG AGAGGGAGGA AAACAACCAA GAAACGAGAG 1800 1801 GAAGAAGTGG ACATTGATTT GGATGACCCT GAGATCAATC ACTTCCCTTT TCCTTTCCAC 1860 1861 GAGCTGATGG TGTGGGCTGT CCTAATGAAG AGGCAGAAGA TGGCCTTATT CTTCTGGCAA 1920 1921 CATGGGGAGG AGGCCATGGC GAAGGCCCTA GTGGCCTGTA AGCTCTGCAA AGCAATGGCC 1980 1981 CACGAGGCAT CAGAGAATGA CATGGTGGAT GACATATCCC AGGAGCTGAA CCACAATTCC 2040 2041 AGGTTGATTT ACTTTTGTAA CAAAGCGAGG AAACTTTGGC AAAGTTTCCT TAGAGATGCG 2100 2101 AAAAGAAATT GGCACCATTT GACAATAGAA ATGGATAATT GGACCAAGAG TCAAACTCCT 2160 2161 GGCCCCAGCC TCCAATTTAT ACTCTCTGCT GCTACATGGA TCGTCTTCTT GGAGCACTCC 2220 2221 TGTCCACAAG TCCCCACTCT TCTAAACCCT CTACTGGCTT CCCATGTCAA TCAAGAAAGA 2280 2281 TCAGAAACTG GCACGGAGTT GGTGGAAAGC CTTCCCTTGA AGCCACATAT TATAGCAATT 2340 2341 GGTCCCAGTG ACCCAGACAA AAAGCCTTGG CTAGTCCTGG CTTTTGAATT ACTCTGCTTA 2400 2401 AGGAGAAGCT GGGAAAACAA AACCCAAAAA CATTTAACTC CAGAAAACAA TGAAAAAACT 2460 2461 GCAATGTTGG GGCGAAACAA TGGAGAGTCA TCCCGGAAGA AGGATGAAGA GGAGGTTCAT 2520 2521 AGCAGGCACA GATTAATCCC CCTCGGAAGA AAGATATATG AATTCTACAA TGCACCCATC 2580 2581 GTGAAGTTCT GGTTTTACAC TTTGGCATAC ATCGGATATC TGATGCTCTT CAATTACATT 2640 2641 GTGCTGGTGA AGATGGATCG TTGGCCTTCT GTCCAGGAAT GGATAGTCAT CTCCTACATT 2700 2701 TTCACACTGG GAATAGAGAA GATGAGAGAG ATTCTGATGT CAGAACCTGG AAAGCTGTTA 2760 2761 CAGAAGGTAA AGGTGTGGCT TCAGGAATAT TGGAACGTCA CAGACCTCAT AGCCATCCTC 2820 2821 CTGTTCTCCA TTGGGATGAT CCTTCGTCTA CAAGACCAGC CATTCAGGAG TGACGGACGG 2880 2881 GTCATATACT GTGTCAACAT CATTTACTGG TATATCCGCT TGCTGGACAT CTTCGGTGTG 2940 2941 AACAAGTACT TGGGACCGTA CGTCATGATG ATTGGAAAAA TGATGATAGA CATGATGTAT 3000 3001 TTTGTCATCA TCATGTTGGT GGTGCTGATG AGCTTCGGGG TTGCCAGACA AGCGATTCTC 3060 3061 TTTCCCAACG AGGAGCCCTC ATGGAAGCTG GCAAAGAACA TCTTTTACAT GCCTTACTGG 3120 3121 ATGATCTATG GGGAAGTGTT TGCAGACCAG ATAGACCCTC CCTGTGGACA AAATGAAACC 3180 3181 AGAGAAGATG GCAAAATAAT CCAGTTGCCC CCATGCAAAA CCGGAGCCTG GATCGTGCCA 3240 3241 GCTATCATGG CCTGCTACCT CTTAGTGGCA AATATCCTTC TGGTCAACCT CCTCATTGCT 3300 3301 GTCTTTAACA ATACGTTCTT TGAAGTGAAA TCCATATCCA ACCAAGTGTG GAAGTTTCAG 3360 3361 AGGTATCAGC TGATCATGAC TTTTCATGAA AGGCCAGTCC TGCCACCGCC TCTGATCATC 3420 3421 TTCAGCCACA TGACAATGAT ATTCCAGCAC CTCTGTTGTC GATGGCGGAA ACACGAAAGC 3480 3481 GATCCGGATG AGAGAGACTA CGGACTGAAA CTTTTCATAA CGGATGACGA GCTCAAGAAA 3540 3541 GTGCATGACT TTGAAGAACA GTGCATAGAA GAATATTTCA GAGAAAAAGA TGACCGATTC 3600 3601 AATTCTTCCA ATGACGAGAG GATACGTGTA ACGTCTGAAA GGGTGGAGAA TATGTCCATG 3660 3661 CGCCTGGAGG AGGTGAACGA ACGGGAGCAC TGCATGAAGG CTTCGCTCCA GACTGTCGAC 3720 3721 ATCAGGCTCG CGCAGCTGGA AGACCTGATT GGACGCATGG CCACGGCAAT GGAGCGGCTC 3780 3781 ACTGGCCTGG AGAGGGCAGA GTCCAACAAG ATACGGTCTC GGACCTCCTC GGACTGTACA 3840 3841 GACACCGCCT ACATTGTGAG ACAGAGCAGC TTCAATAGCC AGGAAGGGAA CGCCTACAAG 3900 3901 CTCCAAGAAA GTATTGACCC TGCAGAGCAT CCTTTTTATT CAGTATAA 3948 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Poa-3674 | Pongo abelii | 97.71 | 3e-157 | 510 |
| LLPS-Ict-3536 | Ictidomys tridecemlineatus | 90.57 | 3e-53 | 209 |
| LLPS-Orc-3807 | Oryctolagus cuniculus | 90.33 | 0.0 | 2258 |
| LLPS-Gaga-0647 | Gallus gallus | 89.47 | 0.0 | 2266 |
| LLPS-Ova-2249 | Ovis aries | 89.43 | 0.0 | 2256 |
| LLPS-Loa-3029 | Loxodonta africana | 89.43 | 0.0 | 2254 |
| LLPS-Lac-2809 | Latimeria chalumnae | 89.25 | 0.0 | 868 |
| LLPS-Chs-0991 | Chlorocebus sabaeus | 88.94 | 0.0 | 2025 |
| LLPS-Mum-4245 | Mus musculus | 88.89 | 0.0 | 2242 |
| LLPS-Pes-2732 | Pelodiscus sinensis | 88.6 | 0.0 | 2191 |
| LLPS-Man-0630 | Macaca nemestrina | 88.58 | 0.0 | 2227 |
| LLPS-Cap-3114 | Cavia porcellus | 88.55 | 0.0 | 2196 |
| LLPS-Paa-1283 | Papio anubis | 88.51 | 0.0 | 2225 |
| LLPS-Mal-4227 | Mandrillus leucophaeus | 88.51 | 0.0 | 2224 |
| LLPS-Aim-2465 | Ailuropoda melanoleuca | 88.51 | 0.0 | 2226 |
| LLPS-Maf-1465 | Macaca fascicularis | 88.51 | 0.0 | 2226 |
| LLPS-Cea-4749 | Cercocebus atys | 88.51 | 0.0 | 2225 |
| LLPS-Caj-2970 | Callithrix jacchus | 88.51 | 0.0 | 2224 |
| LLPS-Pat-1259 | Pan troglodytes | 88.51 | 0.0 | 2221 |
| LLPS-Fec-3659 | Felis catus | 88.51 | 0.0 | 2225 |
| LLPS-Rhb-3873 | Rhinopithecus bieti | 88.51 | 0.0 | 2225 |
| LLPS-Cas-3636 | Carlito syrichta | 88.48 | 0.0 | 1701 |
| LLPS-Gog-2100 | Gorilla gorilla | 88.43 | 0.0 | 2218 |
| LLPS-Hos-2487 | Homo sapiens | 88.43 | 0.0 | 2219 |
| LLPS-Caf-3375 | Canis familiaris | 88.25 | 0.0 | 2261 |
| LLPS-Fia-0212 | Ficedula albicollis | 88.04 | 0.0 | 2259 |
| LLPS-Mod-0220 | Monodelphis domestica | 87.94 | 0.0 | 2239 |
| LLPS-Mam-3449 | Macaca mulatta | 87.53 | 0.0 | 2236 |
| LLPS-Anp-1245 | Anas platyrhynchos | 87.46 | 0.0 | 2155 |
| LLPS-Tag-0665 | Taeniopygia guttata | 87.35 | 0.0 | 2181 |
| LLPS-Ran-0731 | Rattus norvegicus | 87.18 | 0.0 | 2202 |
| LLPS-Anc-3385 | Anolis carolinensis | 86.9 | 0.0 | 2138 |
| LLPS-Mup-3663 | Mustela putorius furo | 86.84 | 0.0 | 2203 |
| LLPS-Eqc-2006 | Equus caballus | 86.81 | 0.0 | 2035 |
| LLPS-Sah-3192 | Sarcophilus harrisii | 86.55 | 0.0 | 1452 |
| LLPS-Dio-3692 | Dipodomys ordii | 86.49 | 0.0 | 2196 |
| LLPS-Mea-1884 | Mesocricetus auratus | 86.3 | 0.0 | 2196 |
| LLPS-Fud-1807 | Fukomys damarensis | 85.99 | 0.0 | 2178 |
| LLPS-Pap-3140 | Pan paniscus | 85.43 | 0.0 | 2131 |
| LLPS-Myl-4003 | Myotis lucifugus | 85.32 | 0.0 | 2129 |
| LLPS-Sus-0829 | Sus scrofa | 84.72 | 0.0 | 1488 |
| LLPS-Bot-3009 | Bos taurus | 84.57 | 0.0 | 1338 |
| LLPS-Otg-2329 | Otolemur garnettii | 84.56 | 0.0 | 2127 |
| LLPS-Aon-3842 | Aotus nancymaae | 83.64 | 0.0 | 2057 |
| LLPS-Pof-0355 | Poecilia formosa | 83.42 | 0.0 | 2045 |
| LLPS-Icp-2384 | Ictalurus punctatus | 83.23 | 0.0 | 1843 |
| LLPS-Orn-2995 | Oreochromis niloticus | 82.55 | 0.0 | 2033 |
| LLPS-Asm-3849 | Astyanax mexicanus | 82.19 | 0.0 | 1832 |
| LLPS-Scf-3153 | Scleropages formosus | 82.07 | 0.0 | 2022 |
| LLPS-Urm-3131 | Ursus maritimus | 80.72 | 0.0 | 1251 |
| LLPS-Xet-3899 | Xenopus tropicalis | 79.94 | 0.0 | 1979 |
| LLPS-Scm-0594 | Scophthalmus maximus | 79.49 | 0.0 | 1998 |
| LLPS-Nol-1137 | Nomascus leucogenys | 79.46 | 0.0 | 2018 |
| LLPS-Leo-0669 | Lepisosteus oculatus | 79.15 | 0.0 | 1999 |
| LLPS-Orl-2986 | Oryzias latipes | 78.56 | 0.0 | 1988 |
| LLPS-Dar-3422 | Danio rerio | 78.37 | 0.0 | 1983 |
| LLPS-Xim-3978 | Xiphophorus maculatus | 77.19 | 0.0 | 1934 |
| LLPS-Gaa-1606 | Gasterosteus aculeatus | 64.19 | 0.0 | 1561 |
| LLPS-Cis-1118 | Ciona savignyi | 51.08 | 9e-66 | 248 |
| LLPS-Drm-0467 | Drosophila melanogaster | 45.13 | 0.0 | 1011 |
| LLPS-Cii-1007 | Ciona intestinalis | 43.24 | 0.0 | 971 |
| LLPS-Cae-2047 | Caenorhabditis elegans | 34.84 | 0.0 | 656 |
| LLPS-Ten-2308 | Tetraodon nigroviridis | 32.35 | 3e-36 | 153 |
| LLPS-Tar-2220 | Takifugu rubripes | 30.55 | 8e-30 | 132 |
| LLPS-Meg-1135 | Meleagris gallopavo | 29.91 | 3e-56 | 218 |