LLPS-Nol-a608
ATP1B1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Sodium/potassium-transporting ATPase subunit beta |
| Gene Name: | ATP1B1 |
| Ensembl Gene: | ENSNLEG00000014934.2 |
| Ensembl Protein: | ENSNLEP00000030219.1 |
| Organism: | Nomascus leucogenys |
| Taxa ID: | 61853 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSNLET00000033108.1 | ENSNLEP00000030219.1 |
| Ensembl | ENSNLET00000019070.2 | ENSNLEP00000018167.1 |
| UniProt | G1RY40, G1RY40_NOMLE | |
| GeneBank | ADFV01184505, ADFV01184504 | |
| RefSeq | XM_012511313.1 | XP_012366767.1 |
| Entrez | 100579331 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MARGKAKEEG SWKKFIWNSE KKEFLGRTGG SWFKILLFYV IFYGCLAGIF IGTIQVMLLT 60 61 ISEFKPTYQD RVAPPGLTQI PQIQKTEISF RPNDPKSYEA YVLNIVRFLE KYKDSAQRDD 120 121 MIFEDCGDVP REPKERGDFN HERGERKVCR FKLEWLGNCS GLNDETYGYK EGKPCIIIKL 180 181 NRVLGFKPKP PKNESLETYP VMKYNPNVLP VQCTGKRDED KDKIGNVEYF GLGNSPGFPL 240 241 QYYPYYGKLL QPKYLQPLLA VQFTNLTMDT EIRIECKAYG ENIGYSEKDR FQGRFDVKIE 300 301 VKS 303 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCCGCG GGAAAGCCAA GGAGGAGGGT AGTTGGAAGA AATTCATCTG GAACTCAGAG 60 61 AAGAAGGAGT TTTTGGGCAG GACCGGTGGC AGTTGGTTTA AGATCCTTCT ATTCTACGTA 120 121 ATATTTTATG GCTGCCTGGC TGGCATCTTC ATCGGAACCA TCCAAGTGAT GCTGCTCACC 180 181 ATCAGTGAAT TTAAGCCCAC ATATCAGGAC CGAGTGGCCC CGCCAGGATT AACACAGATT 240 241 CCTCAGATCC AGAAGACTGA AATTTCCTTT CGTCCTAATG ATCCCAAGAG CTATGAGGCA 300 301 TATGTGCTGA ACATAGTTAG GTTCCTGGAA AAGTACAAAG ATTCAGCCCA GAGAGATGAC 360 361 ATGATTTTTG AAGATTGTGG CGATGTACCC CGTGAACCGA AAGAACGAGG AGACTTTAAT 420 421 CATGAACGAG GAGAGCGAAA GGTCTGCAGA TTCAAGCTTG AGTGGCTGGG AAATTGCTCT 480 481 GGATTAAATG ATGAAACTTA TGGCTACAAA GAGGGCAAAC CATGCATTAT TATAAAGCTC 540 541 AACCGAGTTC TAGGCTTCAA ACCTAAGCCT CCCAAGAATG AGTCCTTGGA GACTTACCCA 600 601 GTGATGAAGT ATAACCCAAA TGTCCTTCCC GTTCAGTGCA CTGGCAAGCG AGATGAAGAT 660 661 AAGGATAAAA TTGGAAATGT GGAGTATTTT GGACTGGGCA ACTCCCCTGG TTTTCCTCTG 720 721 CAGTATTATC CCTACTATGG CAAACTCCTG CAGCCCAAAT ACCTGCAGCC CCTGCTGGCC 780 781 GTACAGTTCA CCAATCTTAC CATGGACACT GAAATTCGCA TAGAGTGTAA GGCGTACGGT 840 841 GAGAACATTG GGTACAGTGA GAAAGACCGT TTTCAGGGAC GTTTTGATGT AAAAATTGAA 900 901 GTTAAGAGCT GA 912 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Sodium:potassium-exchanging ATPase complex | |
Molecular Function | ATP binding | |
Molecular Function | ATPase activator activity | |
Molecular Function | ATPase binding | |
Molecular Function | Potassium ion binding | |
Molecular Function | Sodium ion binding | |
Molecular Function | Sodium:potassium-exchanging ATPase activity | |
Biological Process | ATP metabolic process | |
Biological Process | Cellular potassium ion homeostasis | |
Biological Process | Cellular sodium ion homeostasis | |
Biological Process | Membrane repolarization | |
Biological Process | Positive regulation of potassium ion import across plasma membrane | |
Biological Process | Positive regulation of potassium ion transmembrane transporter activity | |
Biological Process | Positive regulation of sodium ion export across plasma membrane | |
Biological Process | Potassium ion import across plasma membrane | |
Biological Process | Protein localization to plasma membrane | |
Biological Process | Protein stabilization | |
Biological Process | Sodium ion export across plasma membrane |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a629 | Homo sapiens | 0.0 | 618 | undefined |
| LLPS-Mum-a625 | Mus musculus | 0.0 | 588 | undefined |