LLPS-Nef-a034
NFIA_108470
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pyruvate carboxylase |
| Gene Name: | NFIA_108470 |
| Ensembl Gene: | NFIA_108470 |
| Ensembl Protein: | EAW25354 |
| Organism: | Neosartorya fischeri |
| Taxa ID: | 331117 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EAW25354 | EAW25354 |
| UniProt | A1CXK2, A1CXK2_NEOFI | |
| GeneBank | DS027685 | EAW25354.1 |
| RefSeq | XM_001267250.1 | XP_001267251.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAAFRQPEE AVDDTEFVDD HHEHHRDSVH RRLRANSAIM QFQKILVANR GEIPIRIFRT 60 61 AHELSLQTVA IYSYEDRLSM HRQKADEAYM IGRRGQYTPV AAYLAIDEIV KIAQEHGVHL 120 121 IHPGYGFLSE NAEFARKVEK AGIVFVGPTP ETIEALGDKV SARQLAIKCG VPVVPGTPGP 180 181 VERYEEVKAF TDTYGFPIII KAAFGGGGRG MRVVRDQADL RDAFERATSE ARSAFGNGTV 240 241 FVERFLDRPK HIEVQLLGDN HGNVIHLFER DCSVQRRHQK VVEIAPAKDL PNDVRDRILA 300 301 DAVKLAKSVN YRNAGTAEFL VDQQNRYYFI EINPRIQVEH TITEEITGID IVAAQIQIAA 360 361 GATLEQLGLT QDRISTRGFA IQCRITTEDP ANGFRPDTGK IEVYRSAGGN GVRLDGGNGF 420 421 AGAIITPHYD SMLVKCTCRG STYEIARRKV VRALVEFRIR GVKTNIPFLT SLLSHPTFID 480 481 GTCWTTFIDD TPELFALVGS QNRAQKLLAY LGDVAVNGSS IKGQIGEPKL KGEIIKPTLL 540 541 DAAGKPIDVS VPCTQGWKQI IDREGPAAFA KAVRANKGCL IMDTTWRDAH QSLLATRVRT 600 601 IDLLNIAKET SHAYANAYSL ECWGGATFDV AMRFLYEDPW DRLRKLRKAV PNIPFQMLLR 660 661 GANGVAYSSL PDNAIYHFCK QAKKCGVDIF RVFDALNDVD QLEVGIKAVQ AAEGVVEATI 720 721 CYSGDMLNPK KKYNLEYYLA LVDKIVKFNP HILGIKDMAG VLKPQAARLL VGSIRERYPD 780 781 LPIHVHTHDS AGTGVASMVA CAQAGADAVD AATDSMSGMT SQPSVGAILA SLEGTEHDPK 840 841 LNRAHVRAID SYWQQLRLLY SPFEAGLTGP DPEVYEHEIP GGQLTNLLFQ ASQLGLGQQW 900 901 AETKKAYESA NDLLGDIVKV TPTSKVVGDL AQFMVSNKLT PEDVVARAGE LDFPGSVLEF 960 961 LEGLMGQPFG GFPEPLRSKA LRDRRKLEKR PGLYLEPLDL AKIKNQIREK YGSATEYDVA 1020 1021 SYAMYPKVFE DYKKFVQKFG DLSILPTRYF LAKPEIGEEF HVELEQGKVL ILKLLAIGPL 1080 1081 SEQTGQREVF YEVNGEVRQV TVDDNKASVD NTARPKADIG DSSQIGAPMS GVVVEIRVHE 1140 1141 GSEVKKGDPV AVLSAMKMEM VISAPHSGKV SGLLVKEGDS VDGQDLICKI AKA 1193 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCTG CCTTTCGCCA GCCCGAGGAG GCGGTCGATG ACACCGAGTT CGTCGATGAT 60 61 CATCATGAGC ACCACAGAGA CTCGGTCCAC CGCCGGCTAC GTGCCAACTC CGCCATCATG 120 121 CAATTCCAAA AGATCCTCGT CGCCAACCGT GGTGAAATCC CCATCCGTAT CTTCCGTACC 180 181 GCCCACGAAC TTTCCCTGCA GACAGTCGCC ATTTACTCAT ATGAGGATCG TCTGTCCATG 240 241 CACCGCCAGA AGGCCGACGA GGCCTACATG ATCGGTCGTC GCGGTCAATA TACCCCCGTC 300 301 GCTGCCTACT TGGCCATCGA TGAGATCGTC AAGATTGCTC AGGAGCATGG TGTGCACCTG 360 361 ATTCACCCCG GTTACGGCTT CTTGTCTGAG AACGCCGAGT TTGCTCGCAA GGTCGAGAAG 420 421 GCCGGTATTG TCTTCGTGGG CCCCACCCCG GAGACCATCG AAGCCCTCGG CGACAAGGTC 480 481 TCTGCCCGTC AATTGGCCAT CAAGTGCGGC GTTCCCGTGG TCCCCGGTAC TCCGGGTCCC 540 541 GTGGAGCGCT ACGAGGAGGT CAAGGCCTTC ACCGACACCT ATGGCTTCCC CATCATCATC 600 601 AAGGCTGCCT TCGGCGGTGG TGGCCGTGGT ATGCGTGTCG TCCGCGATCA GGCCGATCTG 660 661 CGGGACGCCT TTGAGCGTGC TACCTCCGAG GCCCGCTCCG CGTTTGGTAA CGGCACCGTC 720 721 TTCGTCGAGC GTTTCCTCGA CCGCCCCAAG CACATCGAAG TCCAGCTTCT CGGTGACAAC 780 781 CACGGTAACG TCATCCACCT GTTCGAGCGT GACTGCTCCG TCCAGCGCCG TCACCAGAAG 840 841 GTCGTTGAGA TCGCCCCCGC CAAGGATCTG CCTAACGATG TGCGCGACCG CATTTTGGCT 900 901 GATGCTGTGA AGCTGGCCAA GTCGGTCAAC TACCGCAACG CCGGTACCGC CGAGTTCCTG 960 961 GTTGACCAGC AGAACCGCTA CTACTTCATC GAAATCAACC CTCGTATTCA GGTCGAGCAC 1020 1021 ACCATCACCG AAGAAATCAC CGGCATCGAT ATCGTCGCTG CTCAGATCCA AATCGCTGCC 1080 1081 GGTGCCACTC TGGAGCAGTT GGGGCTGACC CAGGACCGCA TCTCCACCCG CGGTTTCGCC 1140 1141 ATCCAGTGCC GTATCACCAC CGAAGACCCG GCCAACGGCT TCAGACCCGA TACCGGAAAG 1200 1201 ATCGAAGTCT ACCGTTCCGC TGGTGGAAAC GGTGTTCGTC TGGACGGTGG TAACGGTTTC 1260 1261 GCTGGTGCCA TCATCACCCC TCACTACGAC TCCATGCTGG TCAAGTGTAC CTGCCGTGGT 1320 1321 TCCACATACG AGATTGCGCG CCGCAAGGTC GTGCGTGCCC TGGTCGAATT CCGGATTCGC 1380 1381 GGTGTCAAGA CCAACATTCC TTTCCTCACC TCTCTGCTGA GCCACCCCAC CTTCATCGAT 1440 1441 GGCACGTGCT GGACCACCTT CATCGATGAC ACTCCCGAGC TGTTCGCTCT TGTCGGCAGC 1500 1501 CAGAACCGTG CTCAGAAGCT TCTTGCCTAC TTGGGTGATG TCGCCGTTAA CGGCAGCAGC 1560 1561 ATCAAGGGCC AGATCGGTGA GCCTAAGCTC AAGGGCGAGA TCATCAAGCC TACCCTGCTG 1620 1621 GACGCCGCCG GTAAGCCGAT CGACGTGAGC GTTCCCTGCA CCCAGGGTTG GAAGCAGATC 1680 1681 ATCGACCGTG AAGGTCCCGC TGCTTTTGCC AAGGCTGTCC GTGCCAACAA GGGCTGCTTG 1740 1741 ATCATGGACA CCACCTGGCG TGATGCCCAC CAGTCGCTGT TGGCTACTCG TGTCCGCACG 1800 1801 ATCGATCTGC TGAACATCGC CAAGGAAACC AGCCACGCGT ACGCCAACGC TTACAGTTTG 1860 1861 GAATGCTGGG GTGGTGCCAC CTTCGATGTC GCCATGCGCT TCCTCTACGA GGACCCCTGG 1920 1921 GACCGTCTGC GCAAGCTGCG CAAGGCCGTG CCCAACATTC CCTTCCAGAT GCTGCTCCGC 1980 1981 GGTGCCAACG GTGTCGCCTA CTCATCTCTT CCCGACAACG CCATTTACCA CTTCTGCAAG 2040 2041 CAGGCCAAGA AGTGCGGTGT CGACATCTTC CGTGTTTTCG ACGCTCTCAA CGACGTTGAC 2100 2101 CAGCTCGAGG TCGGTATCAA GGCTGTGCAG GCCGCCGAGG GTGTCGTCGA GGCTACCATC 2160 2161 TGCTACAGCG GAGACATGCT GAACCCCAAG AAGAAGTACA ACCTCGAGTA CTACCTGGCG 2220 2221 TTGGTGGACA AGATTGTCAA GTTCAACCCC CACATCCTTG GTATCAAGGA TATGGCCGGT 2280 2281 GTGCTGAAGC CTCAGGCCGC GCGCCTGCTG GTTGGCTCCA TCCGTGAGCG CTACCCCGAC 2340 2341 CTTCCCATCC ACGTCCACAC CCACGACTCT GCCGGTACCG GCGTGGCCTC CATGGTTGCC 2400 2401 TGCGCTCAGG CCGGTGCTGA CGCCGTCGAC GCCGCCACCG ACAGCATGTC CGGTATGACA 2460 2461 TCTCAGCCCA GCGTTGGTGC TATCCTTGCT TCTCTCGAGG GCACCGAGCA CGACCCCAAG 2520 2521 CTCAATCGGG CCCACGTTCG TGCCATTGAC TCCTATTGGC AACAGCTGCG CTTGCTGTAC 2580 2581 TCGCCGTTCG AGGCTGGTCT GACCGGCCCC GACCCTGAGG TCTACGAGCA CGAAATTCCC 2640 2641 GGTGGTCAGC TGACCAACCT CCTCTTCCAG GCCAGTCAGC TCGGCCTGGG TCAGCAGTGG 2700 2701 GCCGAGACCA AGAAGGCTTA TGAGTCGGCC AACGACCTGC TCGGCGACAT TGTCAAGGTC 2760 2761 ACTCCCACCT CCAAGGTTGT CGGTGACCTG GCTCAGTTCA TGGTCTCCAA CAAGCTGACT 2820 2821 CCCGAGGACG TTGTCGCCCG TGCTGGCGAG CTGGACTTCC CCGGCTCTGT CCTTGAATTC 2880 2881 CTCGAGGGTC TCATGGGCCA GCCCTTCGGT GGCTTCCCCG AGCCTCTGCG ATCCAAGGCT 2940 2941 CTGCGTGACC GCCGCAAGCT CGAGAAGCGC CCCGGTCTCT ACCTGGAGCC TCTGGACCTG 3000 3001 GCCAAGATCA AGAACCAGAT TCGGGAGAAG TATGGCTCAG CCACCGAGTA CGACGTGGCC 3060 3061 AGTTACGCCA TGTACCCCAA GGTCTTTGAG GACTACAAGA AGTTCGTGCA GAAGTTTGGT 3120 3121 GATCTCTCCA TCCTGCCTAC CCGCTACTTC TTGGCCAAGC CCGAGATCGG CGAGGAATTC 3180 3181 CACGTCGAGC TGGAGCAGGG TAAGGTCCTG ATCCTCAAGT TGCTGGCTAT CGGCCCCCTG 3240 3241 TCCGAGCAGA CCGGTCAGCG TGAAGTCTTC TACGAGGTCA ATGGTGAGGT CCGTCAGGTC 3300 3301 ACCGTTGACG ACAACAAGGC CTCTGTCGAC AACACCGCCC GCCCCAAGGC CGACATTGGC 3360 3361 GACAGCAGCC AAATCGGTGC TCCCATGAGC GGTGTCGTCG TTGAAATCCG TGTCCACGAG 3420 3421 GGCTCGGAGG TCAAGAAGGG TGACCCCGTT GCCGTTCTGA GCGCCATGAA GATGGAAATG 3480 3481 GTTATCTCTG CTCCTCACAG CGGAAAGGTC TCCGGCCTGC TCGTCAAGGA AGGCGATTCC 3540 3541 GTCGATGGCC AGGACCTCAT CTGTAAGATC GCCAAGGCAT AG 3582 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | ATP binding | |
Molecular Function | Biotin binding | |
Molecular Function | Metal ion binding | |
Molecular Function | Pyruvate carboxylase activity | |
Biological Process | Gluconeogenesis | |
Biological Process | Pyruvate metabolic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a962 | Homo sapiens | 0.0 | 1243 | undefined |
| LLPS-Mum-a947 | Mus musculus | 0.0 | 1248 | undefined |