DrLLPS - Data resource of LLPS

LLPS-Nec-0223
NCU08277

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Eukaryotic translation initiation factor 2 alpha subunit
Gene Name:	NCU08277
Ensembl Gene:	NCU08277
Ensembl Protein:	EAA32669
Organism:	Neurospora crassa
Taxa ID:	367110
LLPS Type:	LLPS regulator

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Mus musculus	LLPS-Mum-1545	Q6ZWX6	Regulator	Nucleolus, Stress granule	52.69	6e-84	262
Drosophila melanogaster	LLPS-Drm-0034	P41374	Regulator	Stress granule	50.54	1e-74	239
Homo sapiens	LLPS-Hos-1729	P05198	Regulator	Nucleolus, Stress granule, Postsynaptic density	52.40	1e-87	272
Rattus norvegicus	LLPS-Ran-0045	P68101	Regulator	Neuronal granule, Stress granule	52.69	6e-84	262
Bos taurus	LLPS-Bot-0108	P68102	Client	Nucleolus	52.69	6e-84	262
Arabidopsis thaliana	LLPS-Art-0284	Q9SIZ2	Client	Nucleolus	55.59	1e-95	293
Saccharomyces cerevisiae	LLPS-Sac-0618	P20459	Client	Stress granule	66.90	9e-128	374

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	EAA32669	EAA32669
UniProt		Q7S8J0, Q7S8J0_NEUCR
GeneBank	CM002239	EAA32669.1
RefSeq	XM_956812.2	XP_961905.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSLSNCRFYE EKYPEIDSFV MVNVKQIADM GAYVKLLEYD NIDGMILLSE LSRRRIRSIQ 60 61 KLIRVGRNEV VVVLRVDKEK GYIDLSKRRV SPEDIVRCEE RYNKSKIVHS IMRHVAEKTL 120 121 VPIEQLYETI GWPLNKKYGH SLDAFKLSIT NPDVWNDIQF PTEAVAEELK TYISKRLTPQ 180 181 PTKVRADVEV TCFGYEGIDA IKTALRTAEA RNTEETQVKC RLVSPPLYVL TNTCLDKNAG 240 241 IARLQEAIQD MRTSIEAAGG HLVVKMEPKA VTESDDAELQ ALMEKREREN AEVSGDESVS 300 301 ESDDNIPETV 310
Nucleotide CDS Sequence (FASTA)
1 ATGTCGCTCT CAAACTGCCG TTTCTATGAG GAGAAGTATC CTGAAATCGA CTCGTTCGTT 60 61 ATGGTCAATG TTAAGCAAAT TGCCGATATG GGCGCCTACG TCAAGCTTCT CGAGTACGAC 120 121 AACATCGACG GCATGATCCT GCTCTCTGAG CTTTCCAGAA GACGTATTCG TTCCATCCAG 180 181 AAGTTGATCC GTGTCGGTCG CAACGAGGTC GTCGTCGTTC TCCGTGTCGA CAAGGAGAAG 240 241 GGTTATATCG ATTTGTCCAA GCGTCGTGTG TCCCCCGAGG ATATCGTTCG TTGCGAGGAG 300 301 CGTTACAACA AGAGCAAGAT CGTCCACTCG ATTATGCGCC ACGTTGCCGA GAAGACTCTT 360 361 GTTCCCATCG AGCAGCTTTA CGAGACAATA GGATGGCCCC TCAACAAGAA ATACGGCCAC 420 421 TCGCTTGATG CCTTCAAGCT TTCGATCACC AACCCCGACG TCTGGAATGA CATCCAGTTC 480 481 CCCACCGAGG CCGTTGCCGA GGAGCTCAAG ACCTACATCA GCAAGCGTTT GACTCCCCAG 540 541 CCTACCAAGG TCCGTGCCGA TGTTGAGGTC ACTTGCTTCG GCTACGAGGG TATCGATGCT 600 601 ATCAAGACCG CTCTCCGCAC TGCGGAGGCT CGCAACACTG AGGAAACCCA GGTCAAGTGC 660 661 AGACTTGTGT CCCCTCCCCT TTATGTCCTT ACCAACACCT GCTTGGACAA GAATGCCGGT 720 721 ATTGCCCGCC TTCAGGAGGC CATTCAAGAC ATGCGGACCA GCATCGAGGC TGCTGGTGGC 780 781 CACCTTGTGG TGAAGATGGA GCCCAAGGCT GTCACTGAGT CCGATGATGC TGAGCTCCAA 840 841 GCTCTTATGG AGAAGCGTGA GCGTGAGAAC GCTGAGGTCA GCGGCGACGA GAGTGTCAGC 900 901 GAGTCCGACG ACAATATCCC CGAGACCGTC TAA 933

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Map-0328	Magnaporthe poae	89.68	2e-173	490
LLPS-Gag-0369	Gaeumannomyces graminis	88.71	4e-172	487
LLPS-Trr-0439	Trichoderma reesei	88.06	1e-169	480
LLPS-Fus-0050	Fusarium solani	87.74	4e-170	482
LLPS-Trv-0247	Trichoderma virens	87.74	1e-169	480
LLPS-Mao-0130	Magnaporthe oryzae	87.74	7e-170	481
LLPS-Cog-0248	Colletotrichum gloeosporioides	87.5	3e-164	467
LLPS-Coo-0405	Colletotrichum orbiculare	87.5	2e-163	464
LLPS-Cogr-0297	Colletotrichum graminicola	87.15	7e-164	466
LLPS-Beb-0135	Beauveria bassiana	86.13	6e-167	474
LLPS-Ved-0128	Verticillium dahliae	85.99	4e-165	469
LLPS-Blg-0725	Blumeria graminis	85.22	6e-162	461
LLPS-Scs-0091	Sclerotinia sclerotiorum	84.69	4e-159	454
LLPS-Fuv-0120	Fusarium verticillioides	83.99	1e-157	450
LLPS-Phn-0151	Phaeosphaeria nodorum	82.07	7e-156	446
LLPS-Pytr-0564	Pyrenophora triticirepentis	81.72	1e-154	442
LLPS-Tum-0186	Tuber melanosporum	81.72	1e-151	434
LLPS-Lem-0157	Leptosphaeria maculans	81.72	6e-155	443
LLPS-Pyt-0503	Pyrenophora teres	81.38	8e-154	441
LLPS-Dos-0177	Dothistroma septosporum	81.03	3e-151	434
LLPS-Fuo-0367	Fusarium oxysporum	79.81	1e-153	441
LLPS-Zyt-0037	Zymoseptoria tritici	79.66	4e-148	426
LLPS-Nef-0142	Neosartorya fischeri	78.57	4e-150	431
LLPS-Ast-0121	Aspergillus terreus	78.57	2e-149	429
LLPS-Asf-0169	Aspergillus flavus	78.57	5e-148	426
LLPS-Asfu-0169	Aspergillus fumigatus	78.06	7e-148	425
LLPS-Asc-0172	Aspergillus clavatus	77.92	4e-149	428
LLPS-Asn-0284	Aspergillus nidulans	77.6	7e-148	425
LLPS-Aso-0051	Aspergillus oryzae	76.83	4e-145	418
LLPS-Asni-0689	Aspergillus niger	73.68	9e-114	335
LLPS-Asg-0547	Ashbya gossypii	67.93	3e-117	347
LLPS-Kop-0018	Komagataella pastoris	67.93	2e-118	350
LLPS-Yal-0034	Yarrowia lipolytica	67.47	9e-117	346
LLPS-Sac-0618	Saccharomyces cerevisiae	66.9	3e-117	347
LLPS-Scp-0384	Schizosaccharomyces pombe	66.44	3e-117	347
LLPS-Scj-0038	Schizosaccharomyces japonicus	65.75	2e-115	343
LLPS-Pug-0594	Puccinia graminis	64.91	2e-105	317
LLPS-Mel-0138	Melampsora laricipopulina	64.56	2e-104	314
LLPS-Scc-0149	Schizosaccharomyces cryophilus	64.38	1e-115	343
LLPS-Miv-0168	Microbotryum violaceum	62.37	1e-98	300
LLPS-Spr-0105	Sporisorium reilianum	61.54	1e-98	299
LLPS-Usm-0464	Ustilago maydis	61.19	6e-97	295
LLPS-Crn-0195	Cryptococcus neoformans	59.3	3e-94	288
LLPS-Chr-0121	Chlamydomonas reinhardtii	59.06	4e-93	286
LLPS-Gor-0799	Gossypium raimondii	57.89	1e-89	278
LLPS-Thc-0964	Theobroma cacao	57.24	2e-87	272
LLPS-Brr-0132	Brassica rapa	56.58	2e-88	275
LLPS-Bro-0301	Brassica oleracea	56.58	2e-88	275
LLPS-Coc-0597	Corchorus capsularis	56.58	4e-90	279
LLPS-Brn-3194	Brassica napus	56.58	2e-88	275
LLPS-Glm-0542	Glycine max	56.58	2e-87	272
LLPS-Via-1557	Vigna angularis	56.58	5e-86	269
LLPS-Phv-0086	Phaseolus vulgaris	56.25	9e-87	270
LLPS-Vir-0471	Vigna radiata	56.25	3e-87	271
LLPS-Arl-0526	Arabidopsis lyrata	56.25	5e-87	271
LLPS-Met-0087	Medicago truncatula	56.25	6e-86	268
LLPS-Mae-0794	Manihot esculenta	55.92	2e-88	275
LLPS-Pot-0366	Populus trichocarpa	55.92	1e-86	270
LLPS-Cus-0388	Cucumis sativus	55.92	6e-87	273
LLPS-Abg-0550	Absidia glauca	55.9	4e-88	273
LLPS-Php-1060	Physcomitrella patens	55.78	5e-86	268
LLPS-Amt-0655	Amborella trichopoda	55.59	2e-86	270
LLPS-Art-0284	Arabidopsis thaliana	55.59	2e-85	267
LLPS-Gas-0143	Galdieria sulphuraria	55.09	5e-88	273
LLPS-Viv-0162	Vitis vinifera	54.93	1e-85	268
LLPS-Sem-0647	Selaginella moellendorffii	54.69	2e-87	272
LLPS-Prp-0256	Prunus persica	54.61	3e-86	269
LLPS-Sol-1191	Solanum lycopersicum	54.61	1e-82	260
LLPS-Sot-0904	Solanum tuberosum	54.61	1e-82	260
LLPS-Nia-1088	Nicotiana attenuata	54.28	1e-82	260
LLPS-Dac-0640	Daucus carota	53.62	1e-80	254
LLPS-Tra-0010	Triticum aestivum	53.51	9e-80	252
LLPS-Chc-0027	Chondrus crispus	53.33	4e-86	268
LLPS-Mea-0689	Mesocricetus auratus	52.88	5e-80	252
LLPS-Tar-1333	Takifugu rubripes	52.88	5e-82	258
LLPS-Rhb-1493	Rhinopithecus bieti	52.54	6e-80	252
LLPS-Man-0024	Macaca nemestrina	52.54	6e-80	252
LLPS-Hos-1729	Homo sapiens	52.54	6e-80	252
LLPS-Pap-0672	Pan paniscus	52.54	6e-80	252
LLPS-Pat-0810	Pan troglodytes	52.54	6e-80	252
LLPS-Nol-0472	Nomascus leucogenys	52.54	6e-80	252
LLPS-Osl-0528	Ostreococcus lucimarinus	52.54	2e-81	256
LLPS-Mam-1320	Macaca mulatta	52.54	6e-80	252
LLPS-Poa-0442	Pongo abelii	52.54	6e-80	252
LLPS-Caj-1580	Callithrix jacchus	52.54	5e-80	252
LLPS-Icp-0743	Ictalurus punctatus	52.54	8e-80	252
LLPS-Gog-1712	Gorilla gorilla	52.54	6e-80	252
LLPS-Aon-1531	Aotus nancymaae	52.54	5e-80	252
LLPS-Cea-0424	Cercocebus atys	52.54	6e-80	252
LLPS-Chs-0816	Chlorocebus sabaeus	52.54	6e-80	252
LLPS-Maf-0932	Macaca fascicularis	52.54	6e-80	252
LLPS-Mal-0718	Mandrillus leucophaeus	52.54	6e-80	252
LLPS-Paa-0633	Papio anubis	52.54	6e-80	252
LLPS-Sei-0417	Setaria italica	52.48	2e-78	256
LLPS-Brd-1171	Brachypodium distachyon	52.46	2e-82	259
LLPS-Orc-1226	Oryctolagus cuniculus	52.2	2e-79	251
LLPS-Pes-0008	Pelodiscus sinensis	52.2	6e-79	249
LLPS-Otg-0962	Otolemur garnettii	52.2	2e-79	251
LLPS-Loa-0386	Loxodonta africana	52.2	2e-78	248
LLPS-Lac-1555	Latimeria chalumnae	52.2	1e-75	241
LLPS-Dar-0256	Danio rerio	52.2	2e-79	250
LLPS-Pof-0230	Poecilia formosa	52.2	7e-79	251
LLPS-Tag-1114	Taeniopygia guttata	52.2	3e-79	250
LLPS-Ict-0108	Ictidomys tridecemlineatus	52.2	2e-79	251
LLPS-Cas-0634	Carlito syrichta	52.2	6e-79	249
LLPS-Cap-2224	Cavia porcellus	52.2	2e-79	251
LLPS-Eqc-0996	Equus caballus	52.2	2e-79	251
LLPS-Caf-0489	Canis familiaris	52.2	2e-79	251
LLPS-Fud-0489	Fukomys damarensis	52.2	2e-79	251
LLPS-Sus-2275	Sus scrofa	52.2	2e-79	251
LLPS-Mum-1545	Mus musculus	52.2	2e-79	251
LLPS-Ova-0241	Ovis aries	52.2	2e-79	251
LLPS-Ere-0046	Erinaceus europaeus	52.2	2e-79	251
LLPS-Ran-0045	Rattus norvegicus	52.2	2e-79	251
LLPS-Bot-0108	Bos taurus	52.2	2e-79	251
LLPS-Sob-0311	Sorghum bicolor	52.15	9e-81	255
LLPS-Orp-0821	Oryza punctata	52.13	6e-82	258
LLPS-Ors-2066	Oryza sativa	52.13	6e-82	258
LLPS-Org-1845	Oryza glaberrima	52.13	6e-82	258
LLPS-Orr-1153	Oryza rufipogon	52.13	6e-82	258
LLPS-Orni-0869	Oryza nivara	52.13	6e-82	258
LLPS-Ori-0162	Oryza indica	52.13	7e-82	258
LLPS-Orb-0441	Oryza barthii	52.13	6e-82	258
LLPS-Hov-0211	Hordeum vulgare	52.13	2e-81	257
LLPS-Orgl-0920	Oryza glumaepatula	52.13	4e-82	258
LLPS-Fec-0091	Felis catus	51.86	2e-78	248
LLPS-Mod-0034	Monodelphis domestica	51.86	2e-78	248
LLPS-Urm-0916	Ursus maritimus	51.86	2e-78	248
LLPS-Anc-1058	Anolis carolinensis	51.86	6e-79	249
LLPS-Asm-1052	Astyanax mexicanus	51.86	2e-79	251
LLPS-Sah-0077	Sarcophilus harrisii	51.86	2e-78	248
LLPS-Ora-0262	Ornithorhynchus anatinus	51.86	2e-78	248
LLPS-Mup-0103	Mustela putorius furo	51.86	2e-78	248
LLPS-Scf-1364	Scleropages formosus	51.86	2e-79	252
LLPS-Xim-2127	Xiphophorus maculatus	51.86	1e-79	251
LLPS-Fia-0114	Ficedula albicollis	51.85	3e-77	245
LLPS-Anp-0273	Anas platyrhynchos	51.84	1e-79	251
LLPS-Meg-0293	Meleagris gallopavo	51.84	2e-79	250
LLPS-Gaga-0134	Gallus gallus	51.84	2e-79	250
LLPS-Orbr-0795	Oryza brachyantha	51.8	8e-80	253
LLPS-Orm-1955	Oryza meridionalis	51.8	4e-81	256
LLPS-Orn-0466	Oreochromis niloticus	51.53	4e-79	250
LLPS-Scm-0452	Scophthalmus maximus	51.53	1e-78	249
LLPS-Ten-1033	Tetraodon nigroviridis	51.53	2e-79	250
LLPS-Lep-0178	Leersia perrieri	51.48	2e-80	254
LLPS-Leo-0792	Lepisosteus oculatus	51.35	5e-77	244
LLPS-Gaa-0286	Gasterosteus aculeatus	51.17	7e-79	249
LLPS-Myl-0357	Myotis lucifugus	51.03	8e-73	234
LLPS-Hea-0143	Helianthus annuus	50.99	2e-78	249
LLPS-Tru-0210	Triticum urartu	50.97	2e-74	239
LLPS-Aim-1252	Ailuropoda melanoleuca	50.95	2e-61	204
LLPS-Drm-0034	Drosophila melanogaster	50.0	8e-71	229
LLPS-Cym-0151	Cyanidioschyzon merolae	49.5	3e-75	240
LLPS-Xet-0348	Xenopus tropicalis	48.76	2e-61	205
LLPS-Zem-0860	Zea mays	47.87	4e-75	241
LLPS-Mua-0228	Musa acuminata	47.7	1e-77	246
LLPS-Put-0615	Puccinia triticina	47.54	4e-09	57.4
LLPS-Cae-0622	Caenorhabditis elegans	46.91	4e-60	202

LLPS-Nec-0223NCU08277

Protein Sequence

Nucleotide Sequence

LLPS-Nec-0223
NCU08277