• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Myl-3573
MDH2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Malate dehydrogenase
Gene Name: MDH2
Ensembl Gene: ENSMLUG00000017795.2
Ensembl Protein: ENSMLUP00000016235.2
Organism: Myotis lucifugus
Taxa ID: 59463
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLSALARPAG  AALRRSFSTS  AQNNAKVAVL  GASGGIGQPL  SLLLKNSPLV  SRLTLYDIAH  60
61    TPGVAADLSH  IETRASVKGY  LGPEQLPDCL  KGCDLVVIPA  GVPRKPGMTR  DDLFNTNATI  120
121   VANLTAACAQ  NCPEAMICVI  ANPVNSTIPI  TSEVFKKHGV  YNPNKIFGVT  TLDVVRANAF  180
181   VAELKGLDPA  RVNVPVIGGH  AGKTIIPLIS  QCTPKVEFPQ  DQLTTLTGRI  QEAGTEVVKA  240
241   KAGAGSATLS  MAYAGARFVF  SLLDAINGKE  GVVECSFVKS  QETDCSYFST  PLLLGKKGIE  300
301   KNLGIGKISS  FEEKMIAEAI  PELKASIKKG  EDFVKNMK  338
Nucleotide CDS Sequence (FASTA)
1     ATGCTCTCCG  CCCTCGCTCG  GCCTGCCGGC  GCCGCTCTCC  GCCGCAGCTT  CAGCACCTCG  60
61    GCCCAGAACA  ATGCTAAAGT  AGCTGTGCTC  GGGGCTTCCG  GAGGAATTGG  GCAGCCCCTT  120
121   TCGCTTCTCC  TGAAGAATAG  CCCTTTGGTG  AGCCGCCTGA  CCCTCTATGA  TATTGCTCAT  180
181   ACACCCGGAG  TGGCCGCAGA  TCTGAGCCAC  ATTGAGACCA  GAGCGTCTGT  GAAAGGCTAC  240
241   CTCGGACCTG  AGCAACTGCC  AGACTGCCTG  AAAGGTTGTG  ATTTGGTGGT  TATTCCAGCT  300
301   GGAGTCCCAA  GAAAACCAGG  CATGACTCGG  GATGACCTGT  TCAACACCAA  TGCCACGATT  360
361   GTGGCCAACC  TGACTGCTGC  CTGTGCCCAG  AATTGCCCTG  AGGCCATGAT  CTGTGTCATT  420
421   GCAAATCCGG  TTAACTCCAC  CATCCCAATC  ACATCTGAAG  TTTTTAAGAA  GCATGGAGTA  480
481   TACAACCCCA  ATAAGATATT  TGGGGTGACA  ACCCTGGACG  TTGTCAGAGC  CAATGCTTTT  540
541   GTTGCAGAAC  TGAAGGGTTT  GGATCCAGCT  CGAGTCAATG  TTCCTGTCAT  TGGTGGCCAT  600
601   GCTGGGAAGA  CCATCATCCC  CCTGATCTCT  CAGTGCACTC  CCAAGGTGGA  ATTCCCCCAG  660
661   GACCAGCTGA  CAACCCTCAC  TGGACGGATC  CAGGAGGCTG  GCACGGAGGT  GGTCAAGGCT  720
721   AAAGCTGGAG  CAGGCTCTGC  CACCTTGTCC  ATGGCATATG  CTGGAGCGCG  GTTTGTCTTT  780
781   TCCCTTTTGG  ATGCAATCAA  CGGAAAGGAA  GGAGTTGTCG  AATGTTCCTT  TGTTAAGTCC  840
841   CAAGAAACGG  ACTGTTCCTA  TTTCTCCACA  CCATTGCTGC  TGGGGAAAAA  GGGCATTGAG  900
901   AAGAATCTAG  GCATTGGCAA  AATCTCCTCT  TTCGAAGAGA  AGATGATAGC  TGAGGCCATT  960
961   CCTGAGCTGA  AAGCCTCAAT  CAAGAAAGGA  GAAGACTTTG  TAAAGAACAT  GAAATGA  1017

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bot-4698Bos taurus95.360.0 635
LLPS-Sus-2519Sus scrofa94.740.0 632
LLPS-Ova-3466Ovis aries94.430.0 625
LLPS-Caj-3417Callithrix jacchus94.430.0 632
LLPS-Hos-1861Homo sapiens94.120.0 630
LLPS-Mea-0856Mesocricetus auratus94.120.0 630
LLPS-Dio-1882Dipodomys ordii94.10.0 628
LLPS-Ict-0605Ictidomys tridecemlineatus93.810.0 630
LLPS-Orc-1455Oryctolagus cuniculus93.810.0 626
LLPS-Fec-3518Felis catus93.810.0 627
LLPS-Pat-0527Pan troglodytes93.810.0 630
LLPS-Pap-1116Pan paniscus93.810.0 630
LLPS-Gog-1616Gorilla gorilla93.810.0 629
LLPS-Mum-3914Mus musculus93.810.0 629
LLPS-Ran-3330Rattus norvegicus93.50.0 629
LLPS-Cas-0605Carlito syrichta93.480.0 627
LLPS-Mam-2378Macaca mulatta93.190.0 624
LLPS-Loa-1852Loxodonta africana93.190.0 625
LLPS-Man-4587Macaca nemestrina93.190.0 624
LLPS-Cea-2471Cercocebus atys93.190.0 624
LLPS-Maf-0525Macaca fascicularis93.060.0 611
LLPS-Cap-2464Cavia porcellus92.880.0 617
LLPS-Rhb-3148Rhinopithecus bieti92.880.0 623
LLPS-Paa-0473Papio anubis92.880.0 624
LLPS-Eqc-1621Equus caballus92.570.0 622
LLPS-Caf-1291Canis familiaris92.570.0 622
LLPS-Mod-0140Monodelphis domestica92.570.0 619
LLPS-Aim-2059Ailuropoda melanoleuca92.570.0 620
LLPS-Fud-0703Fukomys damarensis92.550.0 620
LLPS-Chs-2758Chlorocebus sabaeus92.260.0 619
LLPS-Sah-0163Sarcophilus harrisii92.240.0 617
LLPS-Urm-0905Ursus maritimus91.950.0 619
LLPS-Aon-2061Aotus nancymaae91.640.0 614
LLPS-Mup-2269Mustela putorius furo91.280.0 603
LLPS-Nol-1618Nomascus leucogenys91.020.0 596
LLPS-Mal-2078Mandrillus leucophaeus91.020.0 603
LLPS-Otg-1347Otolemur garnettii90.090.0 580
LLPS-Anc-2303Anolis carolinensis89.440.0 603
LLPS-Anp-2634Anas platyrhynchos88.960.0 590
LLPS-Gaga-4056Gallus gallus88.820.0 596
LLPS-Meg-2179Meleagris gallopavo88.20.0 594
LLPS-Leo-2131Lepisosteus oculatus86.340.0 579
LLPS-Pof-4156Poecilia formosa86.070.0 581
LLPS-Orl-2179Oryzias latipes86.020.0 581
LLPS-Tag-2879Taeniopygia guttata85.80.0 578
LLPS-Gaa-2898Gasterosteus aculeatus85.760.0 577
LLPS-Fia-2533Ficedula albicollis85.710.0 578
LLPS-Poa-4106Pongo abelii85.450.0 559
LLPS-Dar-3317Danio rerio85.450.0 577
LLPS-Xim-2821Xiphophorus maculatus85.450.0 577
LLPS-Lac-2574Latimeria chalumnae84.830.0 577
LLPS-Scf-2258Scleropages formosus84.830.0 576
LLPS-Tar-3341Takifugu rubripes84.830.0 577
LLPS-Ten-1176Tetraodon nigroviridis84.520.0 575
LLPS-Xet-2472Xenopus tropicalis84.160.0 566
LLPS-Orn-1375Oreochromis niloticus84.160.0 570
LLPS-Icp-4228Ictalurus punctatus84.160.0 567
LLPS-Asm-2216Astyanax mexicanus83.850.0 568
LLPS-Ora-3271Ornithorhynchus anatinus75.554e-162 462
LLPS-Cii-1522Ciona intestinalis69.782e-165 473
LLPS-Arl-2350Arabidopsis lyrata61.891e-125 373
LLPS-Amt-2136Amborella trichopoda61.392e-127 378
LLPS-Drm-0540Drosophila melanogaster61.322e-144 419
LLPS-Art-1515Arabidopsis thaliana61.242e-123 368
LLPS-Bro-2840Brassica oleracea60.974e-124 369
LLPS-Gor-2724Gossypium raimondii60.93e-125 373
LLPS-Glm-0254Glycine max60.715e-124 367
LLPS-Prp-1795Prunus persica60.691e-130 384
LLPS-Dac-0969Daucus carota60.693e-132 388
LLPS-Brn-3220Brassica napus60.651e-123 368
LLPS-Osl-0651Ostreococcus lucimarinus60.634e-123 364
LLPS-Pot-2264Populus trichocarpa60.574e-127 377
LLPS-Org-1897Oryza glaberrima60.522e-121 360
LLPS-Coc-2276Corchorus capsularis60.442e-125 373
LLPS-Php-2483Physcomitrella patens60.443e-124 370
LLPS-Mua-1105Musa acuminata60.377e-123 367
LLPS-Brr-0281Brassica rapa60.321e-122 366
LLPS-Orni-1407Oryza nivara60.322e-124 373
LLPS-Sem-1189Selaginella moellendorffii60.264e-122 362
LLPS-Orp-1955Oryza punctata60.191e-120 359
LLPS-Orgl-0077Oryza glumaepatula60.195e-121 360
LLPS-Orb-2002Oryza barthii60.196e-121 360
LLPS-Cus-0309Cucumis sativus60.131e-124 374
LLPS-Cae-1276Caenorhabditis elegans60.131e-130 384
LLPS-Zem-2446Zea mays60.122e-125 373
LLPS-Thc-1434Theobroma cacao59.941e-128 379
LLPS-Asfu-0092Aspergillus fumigatus59.876e-122 362
LLPS-Orr-1392Oryza rufipogon59.873e-125 372
LLPS-Ors-1253Oryza sativa59.871e-125 372
LLPS-Hea-2428Helianthus annuus59.872e-125 372
LLPS-Ori-0806Oryza indica59.871e-125 372
LLPS-Asc-0173Aspergillus clavatus59.872e-120 358
LLPS-Orm-1256Oryza meridionalis59.813e-126 375
LLPS-Sob-2263Sorghum bicolor59.812e-122 365
LLPS-Orbr-0959Oryza brachyantha59.814e-126 375
LLPS-Abg-1944Absidia glauca59.757e-126 371
LLPS-Phv-0732Phaseolus vulgaris59.743e-122 362
LLPS-Vir-1553Vigna radiata59.742e-121 360
LLPS-Via-1327Vigna angularis59.742e-121 360
LLPS-Tru-2018Triticum urartu59.682e-123 367
LLPS-Tra-3009Triticum aestivum59.684e-124 369
LLPS-Nef-1080Neosartorya fischeri59.558e-121 358
LLPS-Nia-1119Nicotiana attenuata59.492e-123 368
LLPS-Hov-1263Hordeum vulgare59.375e-125 372
LLPS-Lep-1285Leersia perrieri59.223e-119 355
LLPS-Viv-0299Vitis vinifera59.052e-123 368
LLPS-Mae-0898Manihot esculenta58.991e-126 374
LLPS-Sot-1467Solanum tuberosum58.991e-126 374
LLPS-Brd-1328Brachypodium distachyon58.93e-119 355
LLPS-Sei-2050Setaria italica58.882e-124 370
LLPS-Asn-1497Aspergillus nidulans58.868e-117 348
LLPS-Sol-2434Solanum lycopersicum58.545e-121 366
LLPS-Chr-0737Chlamydomonas reinhardtii58.333e-123 365
LLPS-Asf-0997Aspergillus flavus58.231e-114 345
LLPS-Aso-0869Aspergillus oryzae58.236e-116 346
LLPS-Ast-0577Aspergillus terreus58.042e-113 340
LLPS-Asni-1101Aspergillus niger57.918e-112 336
LLPS-Gag-0788Gaeumannomyces graminis57.895e-117 349
LLPS-Map-1111Magnaporthe poae57.726e-117 348
LLPS-Pyt-0555Pyrenophora teres57.593e-122 362
LLPS-Mao-0137Magnaporthe oryzae57.596e-118 351
LLPS-Cog-0116Colletotrichum gloeosporioides57.413e-117 349
LLPS-Pytr-1208Pyrenophora triticirepentis57.281e-121 360
LLPS-Nec-1369Neurospora crassa57.285e-119 354
LLPS-Zyt-0764Zymoseptoria tritici57.16e-119 354
LLPS-Lem-0848Leptosphaeria maculans57.13e-122 362
LLPS-Cogr-1627Colletotrichum graminicola57.064e-117 349
LLPS-Spr-1330Sporisorium reilianum56.72e-120 357
LLPS-Coo-1355Colletotrichum orbiculare56.663e-117 349
LLPS-Dos-1267Dothistroma septosporum56.484e-118 352
LLPS-Beb-0539Beauveria bassiana56.481e-110 332
LLPS-Met-2172Medicago truncatula56.452e-123 366
LLPS-Trr-1355Trichoderma reesei56.441e-114 343
LLPS-Trv-1364Trichoderma virens56.277e-116 346
LLPS-Phn-0263Phaeosphaeria nodorum55.861e-121 361
LLPS-Tum-1247Tuber melanosporum55.862e-117 350
LLPS-Usm-0268Ustilago maydis55.766e-119 354
LLPS-Mel-0505Melampsora laricipopulina55.244e-110 332
LLPS-Put-0898Puccinia triticina55.111e-111 335
LLPS-Kop-0888Komagataella pastoris55.084e-112 336
LLPS-Fus-0519Fusarium solani54.911e-112 338
LLPS-Blg-1217Blumeria graminis54.631e-111 335
LLPS-Pug-0298Puccinia graminis54.67e-112 336
LLPS-Crn-0385Cryptococcus neoformans54.359e-119 353
LLPS-Scs-0776Sclerotinia sclerotiorum54.323e-110 332