LLPS-Mup-a099
PANX2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pannexin |
| Gene Name: | PANX2, PANX |
| Ensembl Gene: | ENSMPUG00000002416.1 |
| Ensembl Protein: | ENSMPUP00000002390.1 |
| Organism: | Mustela putorius furo |
| Taxa ID: | 9669 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Structural component of the gap junctions and the hemichannels. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMPUT00000002439.1 | ENSMPUP00000002390.1 |
| UniProt | M3XTJ0, M3XTJ0_MUSPF | |
| GeneBank | AEYP01086349, AEYP01086348 | |
| RefSeq | XM_004775399.2 | XP_004775456.1 |
| Entrez | 101670910 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MHHLLEQSAD MATALLAGEK LRELILPGAQ DDKAGALAAL LLQLKLELPF DRVVTIGTVL 60 61 VPILLVTLVF TKNFAEEPIY CYTPHNFTRD QALYARGYCW TELRDALPGV DASLWPSLFE 120 121 HKLLPYSLLA FAAIMYVPAL GWEFLASTRL TSELNFLLQE IDNCYHRAAE GRAPKIEKQI 180 181 QSKGPGITER ERREIIENAE KEKSPEQNLF EKYLERRGRS NFLAKLYLAR HLLILLLSVA 240 241 PISYLCTYYA TQKQNEFTCA LGAAPDGPAG AGPAVRVSCK LPSVQLQRIV AGVDIVLLCA 300 301 MNLIILVNLI HLFIFRKSNF IFDKLHKVGI KTRRQWRRSQ FCDINILAMF CNENRDHIKS 360 361 LNRLDFITNE SDLMYDNVVR QLLAALAQSN HDATPTVRDA GVQTADPSAN PAEPDGAAEP 420 421 PVVKRPRRKM KWIPTGNPLP QPFKEPLAIM RVDNSKADKP KPVRRKTATD TLIAPLLDAG 480 481 ARAAHHYKGG GADAGPAPDK KHARHFSLDV HPYILGTKKA KPEAVPAAAL PASRSQEGGF 540 541 LSQAEECALG LAAAPTKDTP LPEKEILYPA EPARAALPSG GPFHVCSPPA AATTAPLSPA 600 601 SLGKADPLAI LSRNATHPLL HIGTLYEARE EEDGGPRAAP DVGSLLAIPP PQQILIATFD 660 661 EPRTVVSTVE F 671 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCACCACC TCCTGGAGCA GTCCGCGGAC ATGGCGACGG CGCTGCTGGC CGGGGAGAAG 60 61 CTGCGCGAGC TGATCCTGCC CGGCGCGCAG GACGACAAGG CGGGCGCGTT GGCCGCGCTG 120 121 CTGCTGCAGC TCAAGCTCGA GCTGCCCTTC GACCGCGTGG TCACCATCGG CACCGTGCTC 180 181 GTCCCCATCC TGCTGGTCAC CCTGGTATTC ACCAAGAACT TCGCAGAGGA GCCCATTTAC 240 241 TGCTACACGC CGCACAACTT CACTCGCGAC CAGGCGCTGT ATGCTCGTGG CTACTGCTGG 300 301 ACGGAGCTGC GGGACGCACT GCCCGGCGTG GACGCCAGCC TGTGGCCGTC GCTGTTTGAG 360 361 CACAAGCTGC TGCCCTACTC GCTGCTGGCC TTCGCGGCCA TCATGTATGT GCCGGCGCTG 420 421 GGCTGGGAGT TCCTGGCCTC CACCCGCCTC ACCTCCGAGC TCAACTTCCT GCTGCAGGAG 480 481 ATCGACAACT GCTACCACCG CGCAGCCGAG GGCCGCGCCC CCAAGATCGA AAAGCAGATC 540 541 CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGCGGCGCG AGATCATCGA GAACGCGGAG 600 601 AAGGAGAAGA GCCCTGAGCA GAACCTGTTC GAGAAGTACC TGGAGCGCCG TGGCCGCAGC 660 661 AACTTCCTGG CCAAGCTGTA CCTGGCGCGG CACCTGCTCA TCCTGCTGCT CAGCGTGGCG 720 721 CCCATCTCCT ACCTGTGCAC CTACTACGCC ACCCAGAAGC AGAACGAGTT CACGTGCGCC 780 781 CTGGGCGCGG CCCCGGACGG GCCGGCCGGC GCGGGCCCCG CGGTGCGCGT CAGCTGCAAG 840 841 CTGCCGTCGG TGCAGCTGCA GCGCATCGTG GCCGGCGTGG ACATCGTGCT GCTGTGCGCC 900 901 ATGAACCTCA TCATCCTCGT CAACCTCATC CACCTGTTCA TCTTCCGCAA GAGCAACTTC 960 961 ATCTTCGACA AGCTGCACAA GGTGGGCATC AAGACGCGCC GGCAGTGGCG CCGCTCCCAG 1020 1021 TTCTGCGACA TCAACATCCT GGCCATGTTC TGCAACGAGA ACCGCGACCA CATCAAGTCG 1080 1081 CTCAACCGGC TGGACTTCAT CACCAACGAG AGCGACCTCA TGTACGACAA CGTGGTGCGG 1140 1141 CAGCTGCTGG CCGCGCTGGC CCAGTCCAAC CACGACGCCA CGCCCACCGT GCGCGACGCG 1200 1201 GGGGTGCAGA CGGCCGACCC CAGCGCCAAC CCCGCCGAGC CCGACGGCGC CGCCGAGCCG 1260 1261 CCCGTCGTCA AGCGGCCGCG CAGGAAGATG AAGTGGATCC CCACGGGCAA CCCGCTGCCG 1320 1321 CAGCCCTTCA AGGAGCCGCT GGCCATCATG CGCGTGGACA ACAGCAAGGC CGACAAGCCC 1380 1381 AAGCCCGTGC GCCGCAAGAC GGCCACGGAC ACGCTGATCG CGCCGCTGCT GGACGCGGGC 1440 1441 GCGCGCGCCG CGCACCACTA CAAGGGCGGC GGGGCCGACG CGGGGCCGGC GCCCGACAAG 1500 1501 AAGCACGCGC GCCACTTCTC CCTGGACGTG CACCCCTACA TCCTGGGCAC CAAGAAGGCC 1560 1561 AAGCCCGAGG CCGTGCCCGC CGCCGCCCTG CCCGCCTCCC GGAGCCAGGA AGGGGGTTTC 1620 1621 CTGTCCCAGG CGGAGGAGTG CGCGCTGGGC TTGGCCGCAG CACCCACCAA AGACACTCCG 1680 1681 CTCCCTGAGA AGGAGATCCT GTACCCAGCA GAGCCCGCCC GGGCGGCACT TCCTTCCGGG 1740 1741 GGCCCATTTC ACGTTTGCTC GCCCCCAGCG GCCGCCACCA CGGCCCCTCT GTCGCCAGCC 1800 1801 AGTCTGGGCA AAGCCGACCC CCTCGCCATC CTGAGCCGCA ACGCCACGCA CCCGCTGCTG 1860 1861 CACATCGGCA CGCTGTACGA AGCCCGGGAG GAGGAGGACG GGGGTCCCCG CGCGGCCCCG 1920 1921 GACGTGGGCA GTCTCCTTGC CATCCCCCCC CCGCAGCAGA TCCTCATCGC CACGTTCGAC 1980 1981 GAGCCGAGGA CGGTAGTGAG TACCGTGGAG TTCTGA 2016 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Gap junction | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plasma membrane | |
Molecular Function | Channel activity | |
Biological Process | Cation transport | |
Biological Process | Positive regulation of interleukin-1 secretion | |
Biological Process | Response to ischemia |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a099 | Homo sapiens | 0.0 | 1222 | undefined |
| LLPS-Mum-a102 | Mus musculus | 0.0 | 1212 | undefined |