LLPS-Mum-a530
Napg

▼ OVERVIEW

Status: Reviewed
Protein Name: Gamma-soluble NSF attachment protein
Gene Name: Napg, Snapg
Ensembl Gene: ENSMUSG00000024581.12
Ensembl Protein: ENSMUSP00000122681.1
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Postsynaptic density
"...We report the first direct comparison of the proteome of triplicate isolates of mouse and human cortical postsynaptic densities. The mouse postsynaptic density comprised 1556 proteins and the human one 1461."
Mouse cortex23071613

▼ FUNCTION

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAQKINEGL  EHLAKAEKYL  KTGFLKWKPD  YDSAASEYGK  AAVAFKNAKQ  FEQAKDACLR  60
61    EAVAHENNRA  LFHAAKAYEQ  AGMMLKEMQK  LPEAVQLIEK  ASMMYLENGT  PDTAAMALER  120
121   AGKLIENVDP  EKAVQLYQQT  ANVFENEERL  RQAVELLGKA  SRLLVRGRRF  DEAALSIQKE  180
181   KNIYKEIENY  PTCYKVEFWS  PAERTGTGTK  RTGTDPREEE  HLGKGNPLCV  WPTQILAVGT  240
241   WDRPKKTIAQ  VLVHLHRNDY  VAAERCVRES  YSIPGFNGSE  DCAALEQLLE  GYDQQDQDQV  300
301   SEVCNSPLFK  YMDNDYAKLG  LSLVVPGGGI  KKKSPATPQA  KPDGAAGMAA  EEE  353
Nucleotide CDS Sequence (FASTA)
1     ATGGCAGCCC  AGAAGATCAA  CGAGGGGCTG  GAGCATCTGG  CCAAGGCAGA  GAAGTACCTG  60
61    AAAACTGGTT  TTTTGAAGTG  GAAGCCAGAT  TATGACAGTG  CCGCTTCTGA  ATATGGGAAA  120
121   GCAGCTGTTG  CTTTTAAAAA  TGCCAAACAA  TTTGAGCAAG  CAAAGGATGC  CTGCCTCCGG  180
181   GAAGCTGTTG  CCCATGAAAA  TAACAGGGCT  CTTTTTCATG  CTGCCAAAGC  TTATGAGCAA  240
241   GCTGGCATGA  TGCTGAAGGA  GATGCAGAAG  CTGCCTGAGG  CAGTGCAGCT  GATCGAGAAA  300
301   GCCAGCATGA  TGTACCTGGA  GAACGGCACC  CCGGACACAG  CAGCCATGGC  CCTGGAGCGA  360
361   GCCGGAAAGC  TCATAGAGAA  TGTAGACCCA  GAGAAGGCTG  TACAGCTGTA  TCAGCAGACT  420
421   GCCAATGTTT  TTGAAAATGA  GGAGCGCCTC  CGACAGGCAG  TTGAACTCCT  AGGAAAGGCC  480
481   TCCAGACTGC  TGGTACGAGG  GCGGAGGTTT  GATGAAGCTG  CACTGTCTAT  TCAGAAAGAA  540
541   AAAAATATTT  ACAAGGAAAT  TGAGAACTAC  CCAACTTGTT  ATAAGAAAAC  AATTGCTCAG  600
601   GTCTTAGTTC  ATCTACACAG  AAATGACTAT  GTGGCTGCAG  AGAGGTGTGT  CAGGGAGAGC  660
661   TACAGCATAC  CAGGCTTTAA  CGGCAGTGAG  GACTGTGCGG  CGCTGGAGCA  GCTCCTGGAG  720
721   GGCTACGACC  AGCAGGACCA  AGACCAAGTG  TCCGAGGTCT  GCAACTCGCC  CCTTTTCAAA  780
781   TACATGGACA  ATGATTACGC  TAAGCTGGGC  CTAAGCTTGG  TGGTCCCAGG  AGGAGGAATC  840
841   AAGAAGAAGT  CCCCTGCGAC  ACCCCAGGCC  AAGCCTGATG  GTGCTGCCGG  CATGGCTGCT  900
901   GAAGAGGAGG  AAGACGAGTA  CTCGGGAGGC  CTGTGCTAG  939

▼ KEYWORD

ID
Family
Complete proteome
ER-Golgi transport
Membrane
Phosphoprotein
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrion
Cellular Component
Myelin sheath
Cellular Component
SNARE complex
Cellular Component
Synapse
Cellular Component
Vacuolar membrane
Molecular Function
Soluble NSF attachment protein activity
Molecular Function
Syntaxin binding
Biological Process
Intracellular protein transport
Biological Process
Vesicle-mediated transport

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-a524Rattus norvegicus84.990.0590
LLPS-Pat-a526Pan troglodytes84.140.0587
LLPS-Cea-a530Cercocebus atys84.140.0587
LLPS-Hos-a534Homo sapiens84.140.0587
LLPS-Gog-a520Gorilla gorilla84.140.0587
LLPS-Caj-a521Callithrix jacchus84.140.0587
LLPS-Chs-a517Chlorocebus sabaeus84.140.0587
LLPS-Maf-a528Macaca fascicularis84.140.0588
LLPS-Orc-a499Oryctolagus cuniculus84.140.0587
LLPS-Pap-a523Pan paniscus84.140.0587
LLPS-Paa-a526Papio anubis84.140.0587
LLPS-Nol-a512Nomascus leucogenys84.140.0587
LLPS-Man-a528Macaca nemestrina83.850.0586
LLPS-Aon-a529Aotus nancymaae83.810.0523
LLPS-Otg-a525Otolemur garnettii83.570.0581
LLPS-Ict-a521Ictidomys tridecemlineatus83.570.0582
LLPS-Cap-a522Cavia porcellus83.570.0576
LLPS-Rhb-a520Rhinopithecus bieti83.570.0582
LLPS-Loa-a508Loxodonta africana83.380.0575
LLPS-Ova-a516Ovis aries83.330.0561
LLPS-Eqc-a529Equus caballus83.330.0524
LLPS-Mod-a505Monodelphis domestica83.190.0571
LLPS-Bot-a531Bos taurus83.170.0520
LLPS-Mup-a516Mustela putorius furo83.00.0571
LLPS-Cas-a458Carlito syrichta83.00.0582
LLPS-Caf-a516Canis familiaris82.720.0570
LLPS-Urm-a479Ursus maritimus82.720.0569
LLPS-Fec-a526Felis catus82.720.0569
LLPS-Aim-a510Ailuropoda melanoleuca82.720.0570
LLPS-Poa-a518Pongo abelii82.440.0572
LLPS-Sus-a531Sus scrofa82.440.0570
LLPS-Sah-a478Sarcophilus harrisii81.30.0570
LLPS-Myl-a493Myotis lucifugus81.30.0569
LLPS-Fud-a505Fukomys damarensis80.90.0549
LLPS-Ora-a435Ornithorhynchus anatinus78.163e-167478
LLPS-Dio-a510Dipodomys ordii77.411e-141410
LLPS-Tag-a449Taeniopygia guttata77.180.0538
LLPS-Gaga-a470Gallus gallus76.90.0535
LLPS-Fia-a455Ficedula albicollis76.493e-177504
LLPS-Anp-a427Anas platyrhynchos76.197e-177503
LLPS-Mal-a516Mandrillus leucophaeus75.827e-126370
LLPS-Xet-a458Xenopus tropicalis75.151e-174497
LLPS-Lac-a461Latimeria chalumnae74.221e-169484
LLPS-Anc-a485Anolis carolinensis71.357e-164469
LLPS-Pes-a446Pelodiscus sinensis70.682e-125369
LLPS-Leo-a461Lepisosteus oculatus70.258e-164469
LLPS-Asm-a454Astyanax mexicanus68.831e-151439
LLPS-Scf-a438Scleropages formosus66.293e-157453
LLPS-Mea-a492Mesocricetus auratus66.23e-82257
LLPS-Dar-a460Danio rerio64.51e-145423
LLPS-Orn-a457Oreochromis niloticus64.112e-142416
LLPS-Xim-a465Xiphophorus maculatus63.52e-141412
LLPS-Pof-a461Poecilia formosa63.194e-141412
LLPS-Icp-a461Ictalurus punctatus63.191e-137403
LLPS-Gaa-a444Gasterosteus aculeatus63.012e-134395
LLPS-Scm-a438Scophthalmus maximus62.773e-132389
LLPS-Orl-a449Oryzias latipes62.712e-142415
LLPS-Ten-a436Tetraodon nigroviridis62.322e-142415
LLPS-Tar-a437Takifugu rubripes62.322e-148431