LLPS-Mum-a377
Cnn3
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Calponin-3; Calponin, acidic isoform |
| Gene Name: | Cnn3 |
| Ensembl Gene: | ENSMUSG00000053931.11 |
| Ensembl Protein: | ENSMUSP00000143122.1 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000198620.1 | ENSMUSP00000143122.1 |
| Ensembl | ENSMUST00000199499.1 | ENSMUSP00000143159.1 |
| Ensembl | ENSMUST00000197135.4 | ENSMUSP00000142526.1 |
| Ensembl | ENSMUST00000029773.12 | ENSMUSP00000029773.8 |
| Ensembl | ENSMUST00000198393.1 | ENSMUSP00000143186.1 |
| UniProt | Q9DAW9, CNN3_MOUSE, Q3TW23 | |
| GeneBank | BC055711, AK169021, AK051628, AK169098, AK169410, AK167613, BC085268, AK167201, AK159555, AK159871, AK166578, AK005460 | BAE35180.1, BAE38867.1, BAB24051.1, BAE41156.1, BAE40817.1, BAE39329.1, BAE40881.1, AAH55711.1, BAE35444.1, AAH85268.1, BAC34697.1, BAE39666.1 |
| RefSeq | NM_028044.2 | NP_082320.1 |
| Entrez | 71994 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTHFNKGPSY GLSAEVKNKI ASKYDQQAEE DLRNWIEEVT GLGIGTNFQL GLKDGIILCE 60 61 LINKLQPGSV KKVNESSLNW PQLENIGNFI KAIQAYGMKP HDIFEANDLF ENGNMTQVQT 120 121 TLVALAGLAK TKGFHTTIDI GVKYAEKQTR RFDEGKLKAG QSVIGLQMGT NKCASQAGMT 180 181 AYGTRRHLYD PKMQTDKPFD QTTISLQMGT NKGASQAGML APGTRRDIYD QKLTLQPVDN 240 241 STISLQMGTN KVASQKGMSV YGLGRQVYDP KYCAAPTEPV IHNGSQGTGT NGSEISDSDY 300 301 QAEYPDEYHG EYPDDYPREY QYGDDQGIDY 330 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACCCACT TCAACAAGGG CCCTTCCTAC GGGCTCTCCG CCGAAGTTAA GAACAAGATT 60 61 GCATCCAAGT ATGACCAGCA GGCCGAGGAA GATCTGCGCA ACTGGATAGA AGAGGTGACA 120 121 GGCCTAGGCA TTGGCACCAA CTTCCAGCTG GGGCTGAAGG ACGGCATCAT ATTGTGCGAA 180 181 CTCATAAACA AGCTACAGCC AGGCTCTGTG AAGAAAGTCA ACGAATCCTC ACTAAATTGG 240 241 CCCCAGTTGG AGAATATCGG CAACTTCATT AAAGCTATCC AGGCTTACGG TATGAAGCCC 300 301 CATGATATAT TTGAAGCAAA CGACCTCTTT GAGAATGGCA ACATGACCCA GGTTCAGACG 360 361 ACGCTGGTGG CTCTAGCAGG TCTGGCGAAA ACAAAAGGAT TCCATACAAC CATTGACATT 420 421 GGCGTTAAGT ATGCAGAAAA ACAAACAAGA CGTTTTGATG AAGGCAAATT AAAGGCTGGC 480 481 CAGAGTGTAA TTGGTTTACA GATGGGTACC AACAAATGTG CCAGCCAGGC GGGCATGACA 540 541 GCCTATGGGA CTCGGAGGCA TCTTTATGAT CCCAAGATGC AGACGGACAA ACCCTTTGAC 600 601 CAGACCACGA TTAGCCTGCA GATGGGCACC AACAAAGGGG CCAGCCAGGC TGGGATGTTA 660 661 GCACCGGGCA CCAGAAGAGA CATCTATGAC CAGAAGCTGA CATTACAGCC AGTGGACAAC 720 721 TCGACCATTT CTCTACAGAT GGGCACCAAC AAAGTTGCTT CCCAGAAAGG AATGAGCGTG 780 781 TATGGGCTTG GGCGGCAAGT ATATGACCCC AAGTACTGTG CCGCACCCAC AGAACCTGTC 840 841 ATTCACAACG GAAGCCAGGG CACGGGCACC AATGGGTCGG AAATCAGTGA TAGCGATTAT 900 901 CAGGCAGAAT ACCCCGATGA ATATCATGGC GAGTACCCAG ACGACTACCC TCGGGAGTAC 960 961 CAGTATGGCG ACGACCAGGG CATTGATTAT TAG 993 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Actin cytoskeleton | |
Cellular Component | Cytosol | |
Cellular Component | Dendrite | |
Cellular Component | Dendritic spine | |
Cellular Component | Neuronal cell body | |
Cellular Component | Postsynaptic density | |
Molecular Function | Actin binding | |
Molecular Function | Calmodulin binding | |
Molecular Function | Microtubule binding | |
Biological Process | Actomyosin structure organization | |
Biological Process | Epithelial cell differentiation | |
Biological Process | Negative regulation of ATPase activity |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | PIRSF | CellMarker | RaftProt | |
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||