LLPS-Mum-4083
Trir
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Telomerase RNA component interacting RNase; Exoribonuclease Trir |
| Gene Name: | Trir |
| Ensembl Gene: | ENSMUSG00000041203.9 |
| Ensembl Protein: | ENSMUSP00000044129.8 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end or 3' end with higher efficiency for purine bases (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000047281.9 | ENSMUSP00000044129.8 |
| UniProt | Q9D735, TRIR_MOUSE, Q9D1N3 | |
| GeneBank | AK009653, AK003299, BC023284, BC029622 | BAB26417.1, AAH23284.1, AAH29622.1, BAB22700.1 |
| RefSeq | NM_026760.2 | NP_081036.2 |
| Entrez | 68544 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAARGRRAEP PGREAPGPAG SGRSRWAESG PGTSPESGDD EVSGSSPVSS GVNLFANDGS 60 61 FLELFKRKME EEQRQRQEEP PPGPQRPDPP ASAAAGPGNP KRKGGPGPTL SFVGKRRGGN 120 121 KLALKTGIVA KKQKTEDEVL TSKGDAWAKY MAEVKKYKAH QCGDDDKTRP LVK 173 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCCC GAGGGAGACG GGCGGAGCCT CCGGGTCGGG AGGCGCCCGG CCCGGCGGGC 60 61 AGCGGCAGGA GCCGATGGGC TGAGTCGGGA CCGGGAACGT CACCCGAGAG TGGGGACGAC 120 121 GAGGTGTCGG GCTCGAGTCC GGTGTCCAGC GGTGTGAACT TGTTTGCCAA CGATGGCAGC 180 181 TTCCTGGAGC TGTTCAAGCG GAAGATGGAG GAGGAGCAGC GGCAGCGGCA GGAGGAGCCA 240 241 CCCCCGGGCC CGCAGCGACC CGATCCACCG GCCTCCGCCG CGGCGGGCCC AGGGAATCCG 300 301 AAGAGGAAGG GCGGCCCAGG CCCCACGCTC AGCTTCGTGG GCAAGCGCAG AGGCGGGAAC 360 361 AAACTAGCCC TCAAGACGGG AATAGTAGCC AAGAAGCAGA AGACGGAGGA TGAGGTATTA 420 421 ACAAGTAAAG GTGACGCATG GGCCAAGTAC ATGGCAGAAG TGAAAAAGTA CAAAGCCCAC 480 481 CAGTGCGGGG ATGATGATAA AACTCGGCCC CTGGTGAAAT GA 522 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | 3'-5' exonuclease activity | |
Molecular Function | 5'-3' exonuclease activity | |
Molecular Function | RNA binding | |
Biological Process | RNA phosphodiester bond hydrolysis, exonucleolytic | |
Biological Process | RRNA catabolic process |
▼ ANNOTATION
| Domain | ||||
| InterPro | LCR-eXXXplorer | |||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
| Element | ||||
| microRNA.org | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Tut-1295 | Tursiops truncatus | 100.0 | 7e-39 | 134 |
| LLPS-Mea-2474 | Mesocricetus auratus | 98.67 | 1e-52 | 172 |
| LLPS-Ran-0878 | Rattus norvegicus | 98.0 | 8e-52 | 170 |
| LLPS-Ict-3413 | Ictidomys tridecemlineatus | 92.11 | 3e-50 | 166 |
| LLPS-Cap-4659 | Cavia porcellus | 92.11 | 1e-50 | 167 |
| LLPS-Fud-2172 | Fukomys damarensis | 90.79 | 3e-51 | 168 |
| LLPS-Orc-4136 | Oryctolagus cuniculus | 90.73 | 4e-49 | 163 |
| LLPS-Dio-2082 | Dipodomys ordii | 90.73 | 1e-49 | 164 |
| LLPS-Bot-2244 | Bos taurus | 90.2 | 7e-50 | 166 |
| LLPS-Otg-4315 | Otolemur garnettii | 89.4 | 3e-50 | 166 |
| LLPS-Sus-4183 | Sus scrofa | 88.89 | 2e-48 | 161 |
| LLPS-Fec-3599 | Felis catus | 88.24 | 7e-48 | 160 |
| LLPS-Myl-0178 | Myotis lucifugus | 88.0 | 7e-48 | 160 |
| LLPS-Pap-3832 | Pan paniscus | 86.78 | 5e-46 | 155 |
| LLPS-Nol-2943 | Nomascus leucogenys | 86.78 | 2e-46 | 155 |
| LLPS-Caf-2694 | Canis familiaris | 85.83 | 9e-21 | 90.1 |
| LLPS-Icp-3257 | Ictalurus punctatus | 85.71 | 2e-29 | 112 |
| LLPS-Leo-2914 | Lepisosteus oculatus | 85.71 | 5e-30 | 113 |
| LLPS-Loa-4484 | Loxodonta africana | 84.21 | 2e-48 | 161 |
| LLPS-Dar-2775 | Danio rerio | 84.13 | 8e-30 | 113 |
| LLPS-Asm-3859 | Astyanax mexicanus | 84.13 | 3e-29 | 111 |
| LLPS-Eqc-4833 | Equus caballus | 84.11 | 2e-47 | 159 |
| LLPS-Rhb-1678 | Rhinopithecus bieti | 83.55 | 4e-49 | 163 |
| LLPS-Man-3657 | Macaca nemestrina | 83.55 | 4e-49 | 163 |
| LLPS-Poa-2921 | Pongo abelii | 83.55 | 4e-49 | 163 |
| LLPS-Mam-3672 | Macaca mulatta | 83.55 | 4e-49 | 163 |
| LLPS-Maf-3525 | Macaca fascicularis | 83.55 | 4e-49 | 163 |
| LLPS-Chs-2860 | Chlorocebus sabaeus | 83.55 | 4e-49 | 163 |
| LLPS-Cea-1929 | Cercocebus atys | 83.55 | 4e-49 | 163 |
| LLPS-Mup-3144 | Mustela putorius furo | 83.55 | 2e-48 | 161 |
| LLPS-Paa-1976 | Papio anubis | 83.44 | 1e-48 | 161 |
| LLPS-Pat-0072 | Pan troglodytes | 81.58 | 7e-49 | 162 |
| LLPS-Hos-1509 | Homo sapiens | 81.58 | 7e-49 | 162 |
| LLPS-Gog-0834 | Gorilla gorilla | 81.58 | 7e-49 | 162 |
| LLPS-Caj-4419 | Callithrix jacchus | 80.92 | 5e-49 | 163 |
| LLPS-Aon-0602 | Aotus nancymaae | 80.92 | 4e-49 | 163 |
| LLPS-Scm-4012 | Scophthalmus maximus | 79.37 | 1e-25 | 102 |
| LLPS-Mod-3001 | Monodelphis domestica | 70.31 | 2e-41 | 144 |
| LLPS-Aim-3554 | Ailuropoda melanoleuca | 69.92 | 4e-41 | 142 |
| LLPS-Lac-1071 | Latimeria chalumnae | 67.48 | 2e-36 | 130 |
| LLPS-Anc-0492 | Anolis carolinensis | 64.34 | 4e-41 | 141 |
| LLPS-Orn-0551 | Oreochromis niloticus | 58.68 | 2e-30 | 114 |
| LLPS-Scf-3503 | Scleropages formosus | 57.94 | 1e-28 | 110 |
| LLPS-Tar-1878 | Takifugu rubripes | 57.85 | 5e-30 | 113 |
| LLPS-Xet-2898 | Xenopus tropicalis | 56.56 | 9e-34 | 125 |
| LLPS-Gaga-3681 | Gallus gallus | 56.32 | 1e-13 | 70.1 |
| LLPS-Pof-3086 | Poecilia formosa | 56.2 | 9e-29 | 110 |
| LLPS-Xim-3720 | Xiphophorus maculatus | 56.2 | 7e-29 | 110 |
| LLPS-Orl-2985 | Oryzias latipes | 55.37 | 1e-22 | 94.4 |
| LLPS-Gaa-2474 | Gasterosteus aculeatus | 53.72 | 5e-29 | 110 |
| LLPS-Drm-0690 | Drosophila melanogaster | 51.61 | 8e-09 | 57.4 |