LLPS-Mum-3424
Urb2
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| Gene Name: | Urb2 |
| Ensembl Gene: | ENSMUSG00000031976.14 |
| Ensembl Protein: | ENSMUSP00000034457.8 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000034457.8 | ENSMUSP00000034457.8 |
| Ensembl | ENSMUST00000173168.7 | ENSMUSP00000133547.1 |
| UniProt | E9Q7L1, E9Q7L1_MOUSE | |
| GeneBank | AC139575 | |
| RefSeq | NM_001029876.1, XM_006531150.3, XM_006531151.3 | NP_001025047.1, XP_006531213.1, XP_006531214.1 |
| Entrez | 382038 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAVYSGISF KLKSKTTSWE DKLKLAHFAW ISHQCFLPNK EQVLLDWARQ SLVAFYKKKL 60 61 ELQEDIVERL WIYVDNILHS KKLQNLLKDG KTVNLQLSLV KIINERIEEF SRSGCQRNIC 120 121 AVLSCCQGIL SAPALAVIYT AKPELIVALL SQLCWSACRQ PEGATTAKLF EVIHLALDHY 180 181 LRLQQQQANP KRVFGDMTGH LFQPCLVLRH LLLGGTWTQA SQGQLWQVLS RDIRSKIDAV 240 241 LRAGVFRHDL LSSYKEELLE QHQESVRMGV LKGLLTPMEA VIARLVEPGY VRSDLHALVV 300 301 ASSVPLLFRL FLEAYLQEES QFLCFQVLPR LFGCLQISHL QEGQIEALSL SDWTTELLAI 360 361 EQLLNSVATS NIYNVATDRI RHAETQFHFY RRVAEVLINH SQASVPAWFR CLKILISLNH 420 421 LILEPDLDDL LSSAWIDAEV TEFRAKKAQE VLINTVFQTY AKLRQVPRLF EEVLGVICRP 480 481 AAEALRQPLL ASGLSVALSA CLLELPLSQI LDSWSLVLDK FQSLVMPCLQ SDTDMALKAM 540 541 SLSSLLHCIM FNMQSLDNNM PLPIIRRTQC IMERMLRELV GPLLGLLLDL WSPEPELWQQ 600 601 KVCDSALLLS YTWAQVDATI SLHCSQYYSL GISLARAALD SSNLPLLLPG VEMEFWKKVE 660 661 ECVGQSRSLS RYCLEQLYLQ KVKRTLMRSN SQSKEALQTL RFDTAHILDS SRDCLSQKTA 720 721 AAWDRQVSTM NESIYPVAHW HLIVSNLTVL IPYLCLNDVR YVATVLLRTL PASKAQGSLA 780 781 HGEPHVTLEK ISTALLHSPL FPEMQSLYSA FLTCIIAECS STLCSGAHSD LSLVSQQLPW 840 841 LSGKDDHTIV AHWETRLAKV GPEGVEPRGE IAQNFLSMVK SGFPIKLDEE QLKGLLELLE 900 901 VISALRLDSL SPSYHVHMFF LLFSMAVSTL GHCSCPLALQ FLVKCYRLLS SLQRGKNGRT 960 961 VFRVMYVSDI FEVVLTSLLQ ASAEFQVRED DPAWLQLLQV SGVFLEQLMQ MLTQVKLSLV 1020 1021 LNFGKITAFL SRYRKEASCK EGKIPNLRSR QLLLVALTKL CQSLGPCVKE RRQLLEAPAE 1080 1081 LAELLQQAMM QMGTMLKLCL VSGTTGRRRL PSVLLAAVPT LLEVDMSQHL RDGQPKIAQV 1140 1141 VDTDKTLLSH GTLYQDVYTQ LLEELPALSG NAQSFQAALQ FLTLFLLAPE LHSKETSVFA 1200 1201 SVFYSVQKVL TGPCIPAPVT QDTELHLGAL LTQMFEAGTT EHFGMVLQSI LQGLDVTQAW 1260 1261 RSDLQVVLCA IRLLKLLLKC PLNGEKASLL WRSCPQIITA LMLQHREACR EQPVALAVIE 1320 1321 PVLEVLAVLL RKGEESISNP HHVSLAFNIL LTVPLEHLQP REFGSVFLKM HSVLFSILQC 1380 1381 HSKVMLKAVP SFLNSFNRLL VSVMHEGRQK DKGSVDDLTV VLESARLVER MYSHLATRAE 1440 1441 EFTAFSPFLV AQYVTEVQKV TLYPPVKNLL QEGIYLILDL CMERDIQFLR ASLQAGARDV 1500 1501 FKDLHSDYLK YHKAKHEGEK RYTA 1524 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCTG TTTATTCTGG TATTTCCTTT AAACTTAAAA GCAAGACAAC TTCCTGGGAA 60 61 GATAAACTAA AATTAGCTCA CTTTGCTTGG ATTTCCCATC AGTGCTTTCT ACCAAATAAA 120 121 GAACAAGTTT TACTTGATTG GGCAAGGCAG TCATTGGTTG CATTTTATAA GAAAAAGCTT 180 181 GAACTGCAGG AAGATATTGT TGAAAGGCTC TGGATCTATG TAGATAACAT TCTACATAGT 240 241 AAGAAATTGC AGAACCTCCT TAAGGATGGG AAGACTGTAA ATCTCCAGCT CTCCCTTGTC 300 301 AAGATCATAA ATGAGAGAAT AGAAGAGTTC TCACGTTCAG GATGCCAGAG GAATATCTGT 360 361 GCCGTCCTGA GTTGCTGCCA GGGCATCCTC TCAGCACCTG CCCTTGCTGT CATCTATACA 420 421 GCCAAACCAG AGCTCATTGT GGCTTTGCTG AGCCAGCTCT GCTGGTCGGC CTGCAGACAG 480 481 CCAGAAGGAG CCACGACAGC CAAGCTGTTT GAGGTCATTC ATCTGGCTCT TGACCATTAC 540 541 CTCAGACTTC AGCAACAACA AGCCAACCCT AAGCGTGTCT TTGGAGATAT GACTGGACAC 600 601 CTCTTTCAGC CCTGCCTAGT CCTGAGACAC TTGCTTTTGG GGGGCACGTG GACCCAAGCT 660 661 AGTCAGGGTC AGCTATGGCA GGTACTGAGC AGAGATATCA GGAGCAAGAT TGACGCTGTT 720 721 CTTCGAGCTG GTGTTTTTCG ACACGATTTA CTTTCATCCT ACAAAGAGGA GCTCTTGGAG 780 781 CAGCACCAAG AGAGTGTGAG GATGGGGGTC CTGAAGGGTC TTCTCACTCC AATGGAAGCT 840 841 GTGATTGCAA GACTGGTAGA GCCTGGCTAT GTCAGATCAG ACCTCCATGC TTTGGTTGTG 900 901 GCCAGCTCAG TGCCCTTGTT GTTTAGACTC TTTCTGGAAG CATACCTTCA GGAAGAAAGC 960 961 CAGTTTCTCT GTTTTCAGGT TCTCCCCAGG TTGTTTGGCT GCTTGCAGAT TTCACACCTG 1020 1021 CAGGAGGGGC AGATAGAAGC CCTGTCCCTA TCAGATTGGA CTACAGAGCT TCTGGCTATA 1080 1081 GAGCAACTGT TAAACTCAGT GGCCACCAGT AACATCTACA ATGTGGCTAC TGACAGGATT 1140 1141 CGGCATGCAG AGACACAGTT TCACTTCTAC CGCCGTGTGG CTGAGGTGCT GATCAACCAT 1200 1201 TCACAAGCAT CTGTGCCAGC TTGGTTTCGC TGCCTCAAGA TTTTGATCTC TCTGAATCAT 1260 1261 TTGATTTTAG AGCCAGACCT GGATGACCTG TTGTCTTCGG CTTGGATTGA TGCGGAAGTA 1320 1321 ACAGAATTTC GAGCCAAAAA GGCCCAGGAG GTACTTATCA ACACTGTCTT CCAGACGTAC 1380 1381 GCCAAACTCC GACAGGTGCC ACGGTTGTTT GAGGAGGTTT TGGGGGTGAT CTGCCGCCCA 1440 1441 GCTGCTGAGG CACTGCGGCA GCCTTTGCTT GCCTCAGGCC TCTCTGTGGC TCTCAGTGCA 1500 1501 TGTCTTTTGG AGCTGCCACT GAGTCAGATC CTGGATTCAT GGTCCCTTGT GCTAGATAAG 1560 1561 TTCCAGTCTT TAGTTATGCC CTGTTTGCAG AGTGATACTG ACATGGCTTT AAAGGCAATG 1620 1621 TCACTGAGCT CTCTGCTGCA CTGCATCATG TTCAACATGC AGAGTCTGGA CAATAACATG 1680 1681 CCTCTGCCCA TCATAAGACG GACACAGTGC ATAATGGAGA GGATGCTGAG AGAGCTTGTG 1740 1741 GGGCCCCTTT TGGGCCTTCT CCTGGACCTC TGGAGTCCAG AGCCTGAGCT GTGGCAGCAG 1800 1801 AAGGTGTGTG ACTCTGCACT CTTACTCTCT TACACCTGGG CTCAGGTGGA CGCTACCATC 1860 1861 AGTTTGCACT GCAGCCAGTA TTATTCTCTG GGGATCTCCC TAGCCAGAGC TGCTCTGGAT 1920 1921 AGTTCAAACC TCCCTTTGTT GCTACCAGGT GTAGAAATGG AGTTTTGGAA GAAGGTGGAA 1980 1981 GAGTGTGTAG GCCAGTCCAG GTCTCTCAGT AGGTACTGCT TAGAACAGCT GTATCTTCAG 2040 2041 AAGGTGAAAA GGACTTTAAT GCGGAGTAAT TCACAATCCA AAGAAGCCCT TCAAACCTTG 2100 2101 AGGTTTGACA CTGCTCACAT TCTTGATTCT AGCAGAGACT GTTTAAGTCA GAAGACAGCA 2160 2161 GCTGCCTGGG ATAGGCAGGT GTCGACAATG AATGAGTCCA TATATCCTGT AGCACACTGG 2220 2221 CACTTGATTG TATCAAACCT CACAGTTTTA ATACCCTACC TTTGTTTGAA TGATGTGAGA 2280 2281 TATGTGGCCA CTGTCTTGTT AAGAACTTTA CCAGCAAGTA AAGCCCAGGG AAGCTTGGCA 2340 2341 CATGGTGAGC CACATGTCAC ACTTGAGAAA ATATCCACAG CCCTCCTTCA CAGCCCTCTC 2400 2401 TTTCCAGAGA TGCAGTCCCT CTACTCTGCC TTCCTGACGT GTATCATTGC AGAATGTTCC 2460 2461 AGCACTCTGT GCTCTGGAGC TCATAGTGAC CTGAGTCTTG TTAGTCAGCA GCTCCCCTGG 2520 2521 CTTTCTGGAA AGGACGACCA CACAATCGTG GCTCACTGGG AAACCAGATT GGCAAAAGTT 2580 2581 GGACCTGAAG GTGTAGAACC AAGAGGAGAA ATTGCCCAGA ATTTTCTATC CATGGTCAAG 2640 2641 AGTGGTTTTC CAATCAAGCT GGATGAAGAA CAGCTAAAAG GCCTCCTGGA GCTCTTAGAA 2700 2701 GTCATCTCTG CCCTTCGCCT GGACAGCCTC TCGCCATCTT ACCACGTGCA TATGTTTTTC 2760 2761 CTGCTATTCT CCATGGCTGT CTCCACATTA GGGCATTGCT CTTGCCCACT AGCCCTCCAG 2820 2821 TTCTTGGTGA AGTGCTACCG GCTCCTCAGT AGTCTGCAGA GAGGAAAGAA TGGCCGCACT 2880 2881 GTATTCAGGG TTATGTACGT TAGTGACATC TTTGAGGTTG TGCTGACCTC ACTGTTGCAA 2940 2941 GCCAGTGCCG AGTTTCAGGT TAGGGAGGAT GACCCTGCTT GGCTGCAGCT TCTTCAGGTG 3000 3001 TCAGGGGTGT TCTTAGAGCA GCTGATGCAG ATGCTTACCC AAGTCAAGCT GAGCTTGGTG 3060 3061 CTCAACTTCG GGAAAATCAC TGCCTTTCTC TCAAGGTACA GGAAGGAAGC TTCCTGCAAA 3120 3121 GAGGGGAAAA TCCCGAACCT TCGGAGCAGG CAACTGCTTC TGGTGGCTCT AACCAAGTTG 3180 3181 TGTCAGAGTT TGGGGCCTTG TGTTAAGGAG CGGAGGCAGC TACTGGAGGC CCCAGCAGAG 3240 3241 CTAGCTGAAT TGCTACAGCA GGCCATGATG CAGATGGGCA CCATGCTGAA GCTTTGCCTA 3300 3301 GTGTCCGGGA CTACAGGCCG CCGCCGCCTG CCTTCAGTAC TCCTCGCTGC TGTCCCCACA 3360 3361 CTTTTAGAAG TAGACATGAG CCAGCACCTC AGGGACGGAC AGCCCAAAAT TGCTCAAGTG 3420 3421 GTGGATACAG ACAAAACACT GCTTTCTCAT GGGACACTTT ACCAGGATGT CTACACGCAG 3480 3481 TTGCTGGAGG AGTTGCCAGC CCTGTCGGGG AATGCTCAGT CTTTCCAGGC AGCATTGCAA 3540 3541 TTTCTAACCT TGTTCCTTTT GGCCCCAGAG CTCCATTCCA AGGAGACCTC TGTTTTTGCT 3600 3601 TCCGTCTTTT ATTCTGTGCA GAAAGTTCTT ACAGGTCCAT GCATACCTGC TCCAGTCACT 3660 3661 CAGGATACTG AACTTCACTT GGGAGCCCTG CTCACCCAGA TGTTTGAGGC TGGGACAACA 3720 3721 GAGCACTTTG GGATGGTACT GCAGTCTATT CTTCAGGGGC TGGACGTCAC TCAGGCATGG 3780 3781 AGGTCAGATC TACAGGTTGT TTTGTGTGCC ATTAGACTAC TCAAACTGCT ACTCAAATGT 3840 3841 CCACTCAACG GAGAAAAGGC AAGTTTGCTG TGGCGTTCGT GTCCCCAGAT CATCACGGCT 3900 3901 CTAATGCTGC AACACCGAGA GGCCTGCCGG GAGCAGCCTG TGGCCCTAGC AGTGATTGAG 3960 3961 CCTGTTCTTG AAGTTCTGGC CGTTCTGCTC CGGAAAGGGG AGGAGAGCAT TAGCAACCCT 4020 4021 CACCATGTCA GCCTGGCCTT CAACATCCTG CTCACAGTCC CTCTGGAGCA CCTGCAGCCT 4080 4081 CGGGAGTTTG GCAGCGTCTT CCTGAAGATG CACAGTGTGC TCTTCTCCAT CTTGCAGTGC 4140 4141 CACTCCAAGG TGATGCTGAA GGCCGTTCCA TCTTTCTTGA ACTCCTTCAA TAGACTGTTG 4200 4201 GTTTCAGTTA TGCATGAAGG ACGGCAGAAA GACAAAGGGA GTGTGGATGA CCTGACAGTG 4260 4261 GTCCTTGAGT CTGCACGCCT GGTGGAGAGG ATGTATAGCC ACCTTGCTAC TCGAGCTGAG 4320 4321 GAGTTCACCG CGTTCTCCCC GTTCCTGGTG GCCCAGTATG TGACAGAGGT CCAGAAGGTA 4380 4381 ACCTTGTACC CACCTGTGAA GAACCTGCTT CAGGAGGGGA TTTATCTCAT CTTGGATCTT 4440 4441 TGCATGGAGC GGGATATCCA GTTTCTTCGG GCCTCACTAC AGGCTGGAGC GCGAGATGTC 4500 4501 TTTAAGGATC TGCACAGCGA CTACCTCAAG TACCACAAGG CCAAGCATGA AGGAGAGAAA 4560 4561 AGATATACGG CCTAG 4575 |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ran-4676 | Rattus norvegicus | 90.62 | 0.0 | 2655 |
| LLPS-Mea-2679 | Mesocricetus auratus | 89.36 | 9e-71 | 266 |
| LLPS-Mod-2649 | Monodelphis domestica | 80.0 | 2e-49 | 186 |
| LLPS-Cap-4377 | Cavia porcellus | 76.85 | 9e-160 | 516 |
| LLPS-Myl-3438 | Myotis lucifugus | 74.34 | 9e-111 | 359 |
| LLPS-Dio-2481 | Dipodomys ordii | 72.63 | 0.0 | 2080 |
| LLPS-Pap-3384 | Pan paniscus | 72.05 | 0.0 | 2082 |
| LLPS-Rhb-4523 | Rhinopithecus bieti | 71.92 | 0.0 | 2074 |
| LLPS-Fud-2615 | Fukomys damarensis | 71.83 | 0.0 | 2060 |
| LLPS-Man-2852 | Macaca nemestrina | 71.79 | 0.0 | 2066 |
| LLPS-Pat-2212 | Pan troglodytes | 71.79 | 0.0 | 2077 |
| LLPS-Nol-3105 | Nomascus leucogenys | 71.75 | 0.0 | 2072 |
| LLPS-Cea-3625 | Cercocebus atys | 71.73 | 0.0 | 2070 |
| LLPS-Chs-3843 | Chlorocebus sabaeus | 71.66 | 0.0 | 2074 |
| LLPS-Mal-3913 | Mandrillus leucophaeus | 71.66 | 0.0 | 2068 |
| LLPS-Aon-1571 | Aotus nancymaae | 71.53 | 0.0 | 2060 |
| LLPS-Hos-2612 | Homo sapiens | 71.53 | 0.0 | 2063 |
| LLPS-Mam-3904 | Macaca mulatta | 71.4 | 0.0 | 2063 |
| LLPS-Gog-0946 | Gorilla gorilla | 71.34 | 0.0 | 2057 |
| LLPS-Poa-1706 | Pongo abelii | 71.32 | 0.0 | 2035 |
| LLPS-Maf-1542 | Macaca fascicularis | 71.27 | 0.0 | 2057 |
| LLPS-Caj-4261 | Callithrix jacchus | 71.27 | 0.0 | 2062 |
| LLPS-Ict-3975 | Ictidomys tridecemlineatus | 70.88 | 0.0 | 1999 |
| LLPS-Cas-1239 | Carlito syrichta | 70.73 | 0.0 | 2049 |
| LLPS-Urm-3376 | Ursus maritimus | 70.49 | 0.0 | 2053 |
| LLPS-Aim-1978 | Ailuropoda melanoleuca | 70.3 | 0.0 | 2050 |
| LLPS-Paa-2472 | Papio anubis | 70.03 | 0.0 | 2005 |
| LLPS-Otg-1993 | Otolemur garnettii | 69.96 | 0.0 | 1979 |
| LLPS-Caf-4221 | Canis familiaris | 69.79 | 0.0 | 2022 |
| LLPS-Mup-4477 | Mustela putorius furo | 69.13 | 0.0 | 1984 |
| LLPS-Fec-0594 | Felis catus | 68.83 | 0.0 | 1960 |
| LLPS-Orc-0329 | Oryctolagus cuniculus | 68.81 | 0.0 | 1975 |
| LLPS-Eqc-4419 | Equus caballus | 68.71 | 0.0 | 1904 |
| LLPS-Loa-1218 | Loxodonta africana | 68.63 | 0.0 | 1982 |
| LLPS-Sus-4684 | Sus scrofa | 66.3 | 0.0 | 1887 |
| LLPS-Ova-1073 | Ovis aries | 64.68 | 0.0 | 1831 |
| LLPS-Bot-0518 | Bos taurus | 64.42 | 0.0 | 1838 |
| LLPS-Sah-1367 | Sarcophilus harrisii | 57.83 | 0.0 | 1660 |
| LLPS-Pes-2073 | Pelodiscus sinensis | 50.51 | 0.0 | 1414 |
| LLPS-Ora-0787 | Ornithorhynchus anatinus | 48.27 | 0.0 | 1234 |
| LLPS-Gaga-3634 | Gallus gallus | 47.73 | 0.0 | 1253 |
| LLPS-Tag-3053 | Taeniopygia guttata | 47.31 | 0.0 | 1223 |
| LLPS-Anc-3303 | Anolis carolinensis | 47.19 | 0.0 | 1259 |
| LLPS-Fia-3532 | Ficedula albicollis | 47.14 | 0.0 | 1198 |
| LLPS-Anp-2431 | Anas platyrhynchos | 46.63 | 0.0 | 1176 |
| LLPS-Lac-1458 | Latimeria chalumnae | 44.59 | 0.0 | 1132 |
| LLPS-Tar-1194 | Takifugu rubripes | 40.26 | 8e-64 | 244 |
| LLPS-Xet-1230 | Xenopus tropicalis | 40.09 | 0.0 | 1028 |
| LLPS-Leo-3404 | Lepisosteus oculatus | 39.59 | 0.0 | 901 |
| LLPS-Pof-3596 | Poecilia formosa | 38.85 | 6e-70 | 264 |
| LLPS-Scf-4194 | Scleropages formosus | 37.59 | 0.0 | 809 |
| LLPS-Orl-3774 | Oryzias latipes | 37.07 | 3e-148 | 501 |
| LLPS-Orn-2826 | Oreochromis niloticus | 36.89 | 0.0 | 831 |
| LLPS-Gaa-1399 | Gasterosteus aculeatus | 36.47 | 0.0 | 833 |
| LLPS-Dar-2501 | Danio rerio | 36.26 | 0.0 | 808 |
| LLPS-Cis-0623 | Ciona savignyi | 35.92 | 3e-17 | 89.0 |
| LLPS-Icp-3386 | Ictalurus punctatus | 35.27 | 0.0 | 783 |
| LLPS-Asm-0356 | Astyanax mexicanus | 35.09 | 0.0 | 762 |
| LLPS-Xim-3894 | Xiphophorus maculatus | 34.01 | 0.0 | 741 |
| LLPS-Scm-1898 | Scophthalmus maximus | 32.31 | 0.0 | 669 |