LLPS-Mum-2829
Cenpf
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Centromere protein F |
| Gene Name: | Cenpf |
| Ensembl Gene: | ENSMUSG00000026605.14 |
| Ensembl Protein: | ENSMUSP00000132430.1 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Client |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000165798.1 | ENSMUSP00000132430.1 |
| Ensembl | ENSMUST00000171929.7 | ENSMUSP00000129738.1 |
| Ensembl | ENSMUST00000165962.1 | ENSMUSP00000132759.1 |
| Ensembl | ENSMUST00000165663.1 | ENSMUSP00000130308.1 |
| UniProt | E9Q3P4, E9Q3P4_MOUSE | |
| GeneBank | AC140679 | |
| RefSeq | NM_001081363.2 | NP_001074832.2 |
| Entrez | 108000 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSWALEEWKE GLPSRALQKI QELEGQLEKL KKEKQQRQFQ LDSLEAALQK QKQKVEDGKT 60 61 EGADLKRENQ RLMEICEHLE KSRQKLSHEL QVKESQVNLQ ESQLSSCKKQ IEKLEQELKR 120 121 CKSEFERSQQ VAQSADVSLN PCSTPQKLFA TPLTPSSTYE DLKEKYNKEV EERKRLEEEV 180 181 KALHAKKVSL PVSQATMNHR DIARHQASSS VFPWQQENTP SRLSSDALKT PLRRDGSAAH 240 241 FLGEEVSPNK SSMKTGRGDC SSLPGEPHSA QLLHQAKAQN QDLKSKMTEL ELRLQGQEKE 300 301 MRSQVNKCQD LQLQLEKTKV ELIEKERILN KTRDEVVRST AQYDQAAAKC TTLEQKLKTL 360 361 TEELSCHRQN AESAKRSLEQ RIKEKEKELQ EELSRQHQSF QALDSEYTQM KTRLTQELQQ 420 421 VKHLHSTLQL ELEKVTSVKQ QLERNLEEIR LKLSRAEQAL QASQVAENEL RRSSEEMKKE 480 481 NSLIRSQSEQ RTREVCHLEE ELGKVKVSLS KSQNFAEEMK AKNTSQEIML RDLQEKLNQQ 540 541 ENSLTLEKLK LALADLERQR NCSQDLLKKR EHHIDQLNNK LNKIEKEFET LLSALELKKK 600 601 ECEELKEEKN QISFWKIDSE KLINQIESEK EILLGKINHL ETSLKTQQVS PDSNERIRTL 660 661 EMERENFTVE IKNLQSMLDS KMVEIKTQKQ AYLELQQKSE SSDQKHQKEI ENMCLKANKL 720 721 TGQVESLECK LQLLSSEVVT KDQQYQDLRM EYETLRDLLK SRGSSLVTNE DNQRSSEDNQ 780 781 RSSEDNQRGS LAFEQQPAVS DSFANVMGRK GSINSERSDC SVDGGRSPEH IAILQNRVTS 840 841 LESSLESQNQ MNSDLQMRCE ELLQIKGEVE ENLSKAEQIH QNFVAETNQC ISKLQEDAAV 900 901 HQNIVAETLA TLESKEKELQ LLKEKLEAQQ TEVQKLNKNN CLLEGTLKEL QLLSDTLSSE 960 961 KKEMNSIISL SKKNIEELTQ ANEALKEVNE ALEQEKMNLL QKHEKITSCI AEQERSIAEL 1020 1021 SDQYKQERLQ LLQRCEETEA VLEDLRGNYK TAQENNAKLE CMLSECTALC ENRKNELEQL 1080 1081 KETFAKEQQE FLTKLAFAEE QNRKLMLELE IEQQTVRSEI TNTNKHSMSA TDGLRQECLT 1140 1141 LNEEQNEQQN EVSNLTHENE QLMELTQTKH DSYLAVEPVE NSVKATEDEI GKSSSQYQMD 1200 1201 IDTKDISLDS YKAQLVHLEA LVRILEVQLD QSEEENKKLH LELQTIREEL ETKSSQDPQS 1260 1261 QARTGLKDCD TAEEKYVSML QELSASQNEN AHLQCSLQTA VNKLNELGKM CDVLRVEKLQ 1320 1321 LESELNDSRT ECITATSQMT AEVEKLVSEM KMLNHESALS QNELMKDTSG GEFHDKANHS 1380 1381 SVFLTPLDSS NFCEQMTLSS KEVRVHFAEL QEKFSCLQSE HKILHDQHCE VSSKMSALRS 1440 1441 YVDTLKAENS ALSMSLRTLQ GDLVKEGEPA AEGGHGLPLS FCGADSPSLT NFGETSFYKD 1500 1501 VLEQTGDTCH LSLEGNASAN SCDLDEEFSS SLEEETLTEK ESPPAPGRTV EGLEVLCQVY 1560 1561 LQSLKNLEEK TESQRIMKNK EIEKLEQLLS SERKELSCLR KQYLSEKEQW QQKLTSVTLE 1620 1621 MESKLAEEKQ QTKTLSLELE VARLQLQELD LSSRSLLGTD LESVVRCQND NYDIKESEVY 1680 1681 ISETTEKTPK QDTDQTCDKD IQQDLGLETS VTESETTRLT GEGCEEQPPK TNCEAPAEDK 1740 1741 TQDCSECISE LCSSSNVLVP MDVLEDQGSI QNLQLQKDTL NENLRLLPEV EDWDKKVESL 1800 1801 LNEIMEADSK LSLQEVQLKM KIATCIQLEK IVKDLRKEKA DLSEKLESLP CNQEVCLRVE 1860 1861 RSEEDLGFNL DMGANELLSK STKDNATNTE DNYKEKFLDM ERELTRIKSE KANIEHHILS 1920 1921 VETNLEVVQA EKLCLERDTE SKQKVIIDLK EELFTVISER NRLREELDNV SKESKALDQM 1980 1981 SKKMKEKIEE LESHQRESLR HIGAVESEVK DKADLIQTLS FNVGELTKDK AHLQEQLQNL 2040 2041 QNDSQELSLA IGELEIQIGQ LNKEKESLVK ESQNFQIKLT ESECEKQTIS KALEVALKEK 2100 2101 GEFAVQLSSA QEEVHQLRRG IEKLSVRIEA DEKKHLSAVA KLKESQRESD SLKDTVETLE 2160 2161 RELERSEENQ ELAILDSENL KAEVETLKAQ KDEMTKSLRI FELDLVTVRT ERENLAKQLQ 2220 2221 EKQSRVSELD ERCSSLRRLL EEKEQARVQM EEDSKSAMLM LQMQLKELRE EVAALCNDQE 2280 2281 TLKAQEQSLD QPGEEVHHLK SSIRKLKVHI DADEKKHQNI LEQLKESKHH ADLLKDRVEN 2340 2341 LEQELILSEK NMIFQAEKSK AEIQTLKSEI QRMAQNLQDL QLELISTRSE NENLMKELKK 2400 2401 EQERVSDLET INSSIENLLK DKEQEKVQMK EEAKITVEML QTQLKELNET VVSLCNDQEV 2460 2461 SKTKEQNLGS QVQTLELEKA QLLQDLGEAK NKYIIFQSSV NALTQEVEAG KQKLEKGEKE 2520 2521 IRTLKEQLKS QEQLVCKLAQ VEGEQQLWQK QKLELRNVTM ALEQKVQVLQ SENNTLQSTY 2580 2581 EALQNSHKSL ESELGLIKLE KVALVERVST ISGKEAELQR ELRDMLQKTT QLSEDYNKEK 2640 2641 NRLTEEVEVL REELQNTKAA HLKSVNQLEK ELQRAQGKIK LMLKSCRQLE GEKEMLQKEL 2700 2701 SQLEAAQQQR AGSLVDSNVD EVMTENKALK ETLEEKVKEA DKYLDKYCSL LISHEELEKA 2760 2761 KEILEIEVAR LKSRQSRQDL QSSPLLNSSI PGPSPNTSVS EMKSASGQNK ASGKRQRSSG 2820 2821 IWEHGKRAAP STAETFSKKS RKSDSKSTRP AEHEQETEFE PEGLPEVVKK GFADIPTGKT 2880 2881 SPYILRRTTM ATRTSPRFAT QKLVGSSPSL GKENVVESSK PTAGGSRSQK VKVVQESSAD 2940 2941 SHTAFQELPA KSLTASNIPG RNSTESPREG LRAKRAYPAS SPAAGPDPTN NENCRVQ 2997 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGCTGGG CCCTGGAAGA ATGGAAGGAA GGTCTCCCCT CCAGAGCTCT TCAGAAGATC 60 61 CAAGAGCTTG AAGGACAGCT GGAGAAGCTG AAGAAGGAGA AACAACAGAG GCAGTTCCAG 120 121 CTGGACTCTC TCGAAGCTGC GCTGCAGAAG CAGAAGCAGA AGGTTGAAGA CGGAAAGACT 180 181 GAGGGTGCAG ACCTGAAAAG GGAAAATCAA AGGTTGATGG AGATATGCGA ACATTTGGAG 240 241 AAGTCAAGGC AGAAGCTGTC TCATGAACTT CAAGTTAAGG AGTCACAAGT GAATCTCCAA 300 301 GAGAGCCAAC TGAGCTCATG CAAAAAGCAA ATAGAAAAAC TGGAACAGGA ACTTAAGCGG 360 361 TGTAAATCTG AATTTGAAAG AAGCCAACAA GTTGCACAAT CGGCAGATGT TTCTCTGAAT 420 421 CCATGCAGTA CACCACAGAA ACTCTTTGCA ACTCCACTCA CACCGAGTTC CACATACGAA 480 481 GATCTGAAAG AAAAATATAA TAAAGAAGTT GAAGAACGGA AGAGGTTAGA GGAAGAGGTT 540 541 AAAGCTTTGC ATGCAAAAAA AGTGAGCCTG CCTGTTTCCC AAGCCACCAT GAACCACCGG 600 601 GACATTGCGA GACATCAGGC TTCCTCATCA GTGTTTCCTT GGCAACAGGA AAATACCCCA 660 661 AGTCGCCTTT CATCGGATGC TCTGAAAACC CCACTGAGGA GAGACGGCTC TGCTGCTCAC 720 721 TTTTTGGGGG AAGAAGTGAG TCCTAACAAA TCAAGTATGA AGACAGGGAG AGGAGACTGC 780 781 AGCAGCCTCC CTGACCTAAA AAGCAAGATG ACTGAGTTAG AACTACGCCT GCAAGGGCAA 840 841 GAAAAGGAAA TGAGAAGCCA AGTGAATAAA TGTCAAGACT TACAGCTACA GCTGGAGAAG 900 901 ACGAAAGTGG AATTGATTGA AAAGGAGAGA ATTTTGAATA AAACCAGAGA TGAAGTAGTG 960 961 AGAAGCACAG CACAGTATGA CCAGGCCGCA GCCAAGTGTA CTACCTTGGA ACAAAAGCTG 1020 1021 AAAACTTTGA CTGAGGAGTT GAGTTGTCAC CGACAGAACG CAGAGAGTGC TAAACGTTCT 1080 1081 CTGGAACAGA GGATTAAGGA GAAAGAAAAG GAGCTTCAAG AGGAGCTGTC CCGACAGCAT 1140 1141 CAATCTTTCC AAGCTCTGGA CAGTGAGTAC ACTCAGATGA AAACCAGACT TACCCAGGAG 1200 1201 TTACAGCAAG TCAAGCATTT GCACAGCACC CTCCAGCTGG AACTGGAGAA GGTCACATCA 1260 1261 GTGAAGCAGC AGTTAGAAAG GAATTTGGAA GAAATTAGGC TTAAGTTGAG CAGAGCAGAA 1320 1321 CAAGCTCTTC AGGCAAGTCA GGTCGCAGAA AACGAGCTGA GGAGAAGCAG TGAGGAAATG 1380 1381 AAGAAGGAGA ACAGTCTCAT TAGGAGTCAG TCTGAGCAGA GGACCAGAGA AGTCTGCCAC 1440 1441 CTGGAGGAAG AACTTGGTAA AGTCAAAGTG TCTTTGAGTA AGAGCCAGAA TTTTGCAGAA 1500 1501 GAAATGAAGG CTAAGAATAC CTCTCAGGAA ATCATGTTAC GAGATCTTCA GGAAAAACTA 1560 1561 AATCAGCAAG AAAACTCACT AACTTTAGAG AAGCTGAAAC TTGCCCTAGC TGATCTGGAA 1620 1621 AGACAGCGAA ACTGTTCTCA AGATCTCTTG AAGAAAAGGG AACATCACAT TGATCAACTG 1680 1681 AATAATAAGT TAAATAAGAT AGAGAAAGAG TTTGAAACTT TGCTGAGTGC TTTGGAATTA 1740 1741 AAAAAGAAAG AATGTGAAGA ATTGAAAGAA GAGAAAAATC AGATTTCTTT TTGGAAAATT 1800 1801 GATAGTGAAA AACTCATAAA TCAGATAGAA TCAGAAAAAG AAATCTTATT GGGTAAAATT 1860 1861 AACCACTTAG AGACCAGCCT CAAGACACAA CAAGTAAGTC CTGACTCTAA TGAGAGAATA 1920 1921 AGAACACTGG AGATGGAAAG AGAAAACTTT ACTGTGGAGA TTAAAAACCT TCAAAGTATG 1980 1981 TTAGACAGCA AGATGGTAGA GATCAAGACA CAGAAACAAG CTTACTTGGA ACTGCAGCAG 2040 2041 AAATCCGAAT CCTCGGACCA AAAGCATCAG AAGGAGATAG AGAATATGTG CTTGAAAGCA 2100 2101 AATAAGCTCA CTGGGCAAGT TGAAAGTTTG GAATGTAAGC TTCAGTTATT GTCAAGTGAA 2160 2161 GTAGTGACCA AAGACCAGCA GTACCAAGAC TTGCGTATGG AATATGAGAC ACTGAGGGAT 2220 2221 TTGCTCAAGT CCAGAGGATC TTCTCTGGTG ACAAATGAGG ATAATCAGCG AAGTTCTGAG 2280 2281 GATAATCAGA GAAGTTCTGA GGATAATCAG AGAGGCTCTT TGGCTTTTGA ACAGCAGCCT 2340 2341 GCAGTGAGTG ATTCCTTTGC AAATGTAATG GGGAGAAAAG GAAGCATAAA TTCAGAAAGG 2400 2401 AGTGACTGCT CTGTAGATGG GGGCCGAAGT CCAGAACATA TAGCCATCTT ACAAAATAGA 2460 2461 GTCACTTCAC TTGAAAGTTC CTTGGAGTCT CAAAACCAGA TGAATTCAGA TTTGCAAATG 2520 2521 CGGTGTGAAG AGTTGCTACA AATCAAAGGG GAAGTAGAAG AAAACCTCAG TAAAGCAGAG 2580 2581 CAGATTCATC AGAATTTTGT GGCTGAAACA AATCAATGTA TTAGTAAATT GCAGGAAGAT 2640 2641 GCTGCAGTTC ATCAGAATAT TGTTGCTGAG ACTTTAGCAA CCCTTGAGAG TAAGGAAAAA 2700 2701 GAGTTACAGC TTTTGAAAGA AAAATTAGAA GCTCAGCAAA CAGAGGTTCA AAAGTTAAAT 2760 2761 AAGAATAACT GTCTTCTTGA AGGTACTCTG AAGGAGCTAC AGCTTTTATC TGACACTCTG 2820 2821 AGCTCAGAGA AGAAGGAAAT GAATTCTATC ATCTCATT 2858 |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mea-4167 | Mesocricetus auratus | 76.0 | 0.0 | 3856 |
| LLPS-Nol-1938 | Nomascus leucogenys | 67.84 | 3e-122 | 439 |
| LLPS-Tut-0847 | Tursiops truncatus | 67.84 | 2e-119 | 430 |
| LLPS-Bot-1085 | Bos taurus | 67.54 | 2e-117 | 424 |
| LLPS-Ova-1029 | Ovis aries | 67.54 | 6e-118 | 426 |
| LLPS-Ict-4468 | Ictidomys tridecemlineatus | 67.4 | 0.0 | 3281 |
| LLPS-Cea-1331 | Cercocebus atys | 66.96 | 3e-119 | 430 |
| LLPS-Eqc-4123 | Equus caballus | 66.77 | 7e-104 | 379 |
| LLPS-Mal-1121 | Mandrillus leucophaeus | 66.67 | 4e-118 | 426 |
| LLPS-Paa-1535 | Papio anubis | 66.67 | 6e-119 | 429 |
| LLPS-Mup-2909 | Mustela putorius furo | 66.67 | 6e-114 | 412 |
| LLPS-Man-2355 | Macaca nemestrina | 66.37 | 3e-118 | 427 |
| LLPS-Mam-3313 | Macaca mulatta | 66.37 | 2e-118 | 427 |
| LLPS-Maf-1338 | Macaca fascicularis | 66.37 | 1e-118 | 427 |
| LLPS-Poa-1591 | Pongo abelii | 66.17 | 0.0 | 2810 |
| LLPS-Cas-1525 | Carlito syrichta | 66.08 | 1e-118 | 428 |
| LLPS-Hos-0204 | Homo sapiens | 65.88 | 0.0 | 2794 |
| LLPS-Pap-4124 | Pan paniscus | 65.84 | 0.0 | 2793 |
| LLPS-Pat-0683 | Pan troglodytes | 65.77 | 0.0 | 2789 |
| LLPS-Chs-1794 | Chlorocebus sabaeus | 65.65 | 0.0 | 2803 |
| LLPS-Aon-0167 | Aotus nancymaae | 65.58 | 0.0 | 2791 |
| LLPS-Sus-2422 | Sus scrofa | 65.5 | 5e-114 | 412 |
| LLPS-Otg-1755 | Otolemur garnettii | 65.31 | 9e-115 | 415 |
| LLPS-Dio-0337 | Dipodomys ordii | 64.92 | 0.0 | 3070 |
| LLPS-Rhb-2972 | Rhinopithecus bieti | 64.15 | 0.0 | 2719 |
| LLPS-Gog-1408 | Gorilla gorilla | 63.81 | 0.0 | 2680 |
| LLPS-Aim-3203 | Ailuropoda melanoleuca | 63.32 | 0.0 | 2647 |
| LLPS-Urm-1186 | Ursus maritimus | 63.23 | 1e-116 | 421 |
| LLPS-Caf-3335 | Canis familiaris | 63.23 | 4e-115 | 412 |
| LLPS-Tar-0004 | Takifugu rubripes | 63.16 | 4e-09 | 67.4 |
| LLPS-Myl-1474 | Myotis lucifugus | 62.86 | 0.0 | 2590 |
| LLPS-Orc-0080 | Oryctolagus cuniculus | 62.21 | 0.0 | 2926 |
| LLPS-Fud-0183 | Fukomys damarensis | 60.26 | 0.0 | 2841 |
| LLPS-Cap-2907 | Cavia porcellus | 58.36 | 0.0 | 2732 |
| LLPS-Pof-2798 | Poecilia formosa | 52.31 | 2e-06 | 58.2 |
| LLPS-Anp-1868 | Anas platyrhynchos | 48.96 | 2e-81 | 305 |
| LLPS-Sah-1157 | Sarcophilus harrisii | 48.84 | 3e-75 | 285 |
| LLPS-Ora-1083 | Ornithorhynchus anatinus | 48.38 | 0.0 | 1533 |
| LLPS-Anc-2069 | Anolis carolinensis | 48.13 | 7e-109 | 394 |
| LLPS-Mod-3775 | Monodelphis domestica | 44.94 | 0.0 | 1490 |
| LLPS-Gaa-0635 | Gasterosteus aculeatus | 42.97 | 3e-91 | 338 |
| LLPS-Orl-2017 | Oryzias latipes | 42.88 | 1e-88 | 329 |
| LLPS-Orn-1400 | Oreochromis niloticus | 42.27 | 8e-92 | 340 |
| LLPS-Xet-1880 | Xenopus tropicalis | 42.27 | 4e-96 | 353 |
| LLPS-Xim-1605 | Xiphophorus maculatus | 41.65 | 5e-93 | 343 |
| LLPS-Scm-2161 | Scophthalmus maximus | 41.34 | 3e-93 | 344 |
| LLPS-Tag-0879 | Taeniopygia guttata | 40.69 | 0.0 | 743 |
| LLPS-Scf-3465 | Scleropages formosus | 40.34 | 2e-11 | 75.1 |
| LLPS-Dar-0329 | Danio rerio | 40.09 | 1e-108 | 394 |
| LLPS-Fia-2571 | Ficedula albicollis | 38.57 | 0.0 | 986 |
| LLPS-Lac-1348 | Latimeria chalumnae | 38.4 | 2e-177 | 619 |
| LLPS-Leo-2363 | Lepisosteus oculatus | 38.14 | 4e-33 | 146 |
| LLPS-Meg-1384 | Meleagris gallopavo | 36.65 | 0.0 | 1043 |
| LLPS-Gaga-2643 | Gallus gallus | 35.49 | 6e-30 | 135 |
| LLPS-Icp-0894 | Ictalurus punctatus | 32.98 | 4e-18 | 96.7 |