LLPS-Mum-2351
Ssbp1
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Single-stranded DNA-binding protein, mitochondrial |
| Gene Name: | Ssbp1 |
| Ensembl Gene: | ENSMUSG00000029911.14 |
| Ensembl Protein: | ENSMUSP00000113815.1 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Postsynaptic density | "...We report the first direct comparison of the proteome of triplicate isolates of mouse and human cortical postsynaptic densities. The mouse postsynaptic density comprised 1556 proteins and the human one 1461." | Mouse cortex | 23071613 |
| Nucleolus | Predicted from orthologs | N/A | (View) |
▼ FUNCTION
| This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000117830.1 | ENSMUSP00000113815.1 |
| Ensembl | ENSMUST00000114779.8 | ENSMUSP00000110427.2 |
| Ensembl | ENSMUST00000121360.7 | ENSMUSP00000113563.1 |
| Ensembl | ENSMUST00000031971.12 | ENSMUSP00000031971.6 |
| Ensembl | ENSMUST00000117411.7 | ENSMUSP00000114082.1 |
| UniProt | Q9CYR0, SSBP_MOUSE | |
| GeneBank | AK013425 | BAB28850.1 |
| RefSeq | NM_028358.2, NM_212468.3, XM_006506329.2, XM_017321664.1 | NP_082634.1, NP_997633.1, XP_006506392.1, XP_017177153.1 |
| Entrez | 381760 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MFRRPVLQVF RQFVRHESEV ASSLVLERSL NRVQLLGRVG QDPVMRQVEG KNPVTIFSLA 60 61 TNEMWRSGDS EVYQMGDVSQ KTTWHRISVF RPGLRDVAYQ YVKKGARIFV EGKVDYGEYM 120 121 DKNNVRRQAT TIIAGKKLVV HSVSGCSLEG LA 152 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTTTCGAA GACCTGTGTT ACAGGTATTT CGTCAGTTTG TAAGACATGA GTCTGAAGTA 60 61 GCCAGCAGTT TGGTTCTTGA ACGATCTCTG AATCGTGTTC AGTTACTTGG ACGAGTAGGT 120 121 CAGGACCCTG TCATGAGACA GGTGGAAGGA AAAAACCCAG TCACAATATT TTCTCTAGCA 180 181 ACAAATGAGA TGTGGCGATC AGGGGATAGT GAAGTATACC AAATGGGTGA CGTTAGTCAG 240 241 AAGACGACGT GGCACAGAAT ATCAGTGTTT CGACCAGGCC TCAGAGATGT GGCATATCAG 300 301 TATGTGAAAA AGGGGGCTCG TATATTTGTG GAAGGGAAAG TGGACTATGG CGAGTACATG 360 361 GATAAAAACA ATGTGAGGCG GCAAGCAACA ACAATCATAG CTGGTAAGAA GCTCGTGGTG 420 421 CACAGTGTCT CTGGTTGTTC ATTGGAAGGG TTGGCGTAG 459 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial nucleoid | |
Cellular Component | Mitochondrion | |
Molecular Function | Chromatin binding | |
Molecular Function | Single-stranded DNA binding | |
Biological Process | Mitochondrial DNA replication | |
Biological Process | Mitochondrion morphogenesis | |
Biological Process | Positive regulation of helicase activity |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | PIRSF | CellMarker | RaftProt | |
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ran-1688 | Rattus norvegicus | 97.76 | 1e-92 | 272 |
| LLPS-Mea-3652 | Mesocricetus auratus | 96.27 | 1e-92 | 272 |
| LLPS-Cas-2144 | Carlito syrichta | 96.27 | 8e-92 | 270 |
| LLPS-Bot-1934 | Bos taurus | 94.03 | 1e-89 | 265 |
| LLPS-Mup-2267 | Mustela putorius furo | 94.03 | 2e-89 | 264 |
| LLPS-Mal-0163 | Mandrillus leucophaeus | 94.03 | 3e-91 | 269 |
| LLPS-Fud-0697 | Fukomys damarensis | 94.03 | 1e-89 | 265 |
| LLPS-Caf-1336 | Canis familiaris | 94.03 | 1e-89 | 265 |
| LLPS-Otg-0601 | Otolemur garnettii | 94.03 | 4e-90 | 266 |
| LLPS-Fec-4146 | Felis catus | 93.38 | 4e-88 | 261 |
| LLPS-Aim-1097 | Ailuropoda melanoleuca | 93.28 | 4e-89 | 263 |
| LLPS-Myl-1206 | Myotis lucifugus | 93.28 | 9e-90 | 265 |
| LLPS-Paa-2219 | Papio anubis | 93.28 | 1e-90 | 267 |
| LLPS-Cea-4094 | Cercocebus atys | 93.28 | 1e-90 | 267 |
| LLPS-Maf-0346 | Macaca fascicularis | 93.28 | 9e-91 | 267 |
| LLPS-Mam-1150 | Macaca mulatta | 93.28 | 9e-91 | 267 |
| LLPS-Man-4144 | Macaca nemestrina | 93.28 | 9e-91 | 267 |
| LLPS-Rhb-2234 | Rhinopithecus bieti | 93.28 | 1e-90 | 267 |
| LLPS-Sus-4453 | Sus scrofa | 92.54 | 1e-88 | 262 |
| LLPS-Chs-1147 | Chlorocebus sabaeus | 92.54 | 8e-90 | 265 |
| LLPS-Poa-2530 | Pongo abelii | 92.54 | 3e-90 | 266 |
| LLPS-Loa-0808 | Loxodonta africana | 92.54 | 4e-88 | 261 |
| LLPS-Orc-3651 | Oryctolagus cuniculus | 92.54 | 4e-89 | 263 |
| LLPS-Ova-3630 | Ovis aries | 91.79 | 2e-86 | 256 |
| LLPS-Gog-4044 | Gorilla gorilla | 91.79 | 2e-89 | 264 |
| LLPS-Nol-1195 | Nomascus leucogenys | 91.79 | 7e-90 | 265 |
| LLPS-Hos-0382 | Homo sapiens | 91.79 | 2e-89 | 264 |
| LLPS-Pat-0775 | Pan troglodytes | 91.79 | 2e-89 | 264 |
| LLPS-Pap-2319 | Pan paniscus | 91.79 | 2e-89 | 264 |
| LLPS-Tut-0007 | Tursiops truncatus | 90.3 | 3e-87 | 258 |
| LLPS-Ere-0707 | Erinaceus europaeus | 90.3 | 5e-88 | 260 |
| LLPS-Leo-2125 | Lepisosteus oculatus | 90.0 | 7e-34 | 120 |
| LLPS-Aon-3299 | Aotus nancymaae | 89.55 | 1e-86 | 257 |
| LLPS-Anc-1850 | Anolis carolinensis | 88.97 | 3e-85 | 253 |
| LLPS-Dio-2537 | Dipodomys ordii | 88.73 | 2e-89 | 265 |
| LLPS-Caj-2747 | Callithrix jacchus | 87.76 | 8e-93 | 273 |
| LLPS-Eqc-1321 | Equus caballus | 86.84 | 7e-90 | 266 |
| LLPS-Tag-1193 | Taeniopygia guttata | 86.72 | 2e-79 | 238 |
| LLPS-Pes-0962 | Pelodiscus sinensis | 86.57 | 2e-85 | 254 |
| LLPS-Cap-1458 | Cavia porcellus | 86.05 | 3e-76 | 230 |
| LLPS-Ora-1900 | Ornithorhynchus anatinus | 85.07 | 1e-81 | 244 |
| LLPS-Fia-2463 | Ficedula albicollis | 85.07 | 3e-82 | 246 |
| LLPS-Urm-1239 | Ursus maritimus | 84.72 | 1e-84 | 252 |
| LLPS-Anp-2630 | Anas platyrhynchos | 83.85 | 1e-76 | 231 |
| LLPS-Ict-4020 | Ictidomys tridecemlineatus | 81.65 | 2e-86 | 258 |
| LLPS-Xet-2069 | Xenopus tropicalis | 81.48 | 5e-77 | 233 |
| LLPS-Mod-3344 | Monodelphis domestica | 81.2 | 1e-73 | 224 |
| LLPS-Gaga-1018 | Gallus gallus | 80.74 | 7e-77 | 232 |
| LLPS-Sah-3287 | Sarcophilus harrisii | 79.72 | 4e-82 | 246 |
| LLPS-Meg-0312 | Meleagris gallopavo | 79.63 | 2e-57 | 182 |
| LLPS-Orl-2781 | Oryzias latipes | 79.41 | 4e-73 | 224 |
| LLPS-Gaa-3615 | Gasterosteus aculeatus | 79.1 | 6e-72 | 219 |
| LLPS-Xim-1003 | Xiphophorus maculatus | 79.1 | 1e-73 | 224 |
| LLPS-Pof-2084 | Poecilia formosa | 79.1 | 2e-73 | 223 |
| LLPS-Scf-1063 | Scleropages formosus | 78.36 | 1e-71 | 219 |
| LLPS-Icp-2356 | Ictalurus punctatus | 78.36 | 5e-71 | 217 |
| LLPS-Asm-1380 | Astyanax mexicanus | 78.36 | 4e-71 | 218 |
| LLPS-Orn-1135 | Oreochromis niloticus | 77.61 | 4e-71 | 218 |
| LLPS-Dar-2899 | Danio rerio | 76.87 | 6e-72 | 219 |
| LLPS-Tar-0954 | Takifugu rubripes | 76.12 | 4e-71 | 218 |
| LLPS-Scm-1926 | Scophthalmus maximus | 74.63 | 4e-68 | 212 |
| LLPS-Drm-1739 | Drosophila melanogaster | 42.48 | 8e-25 | 99.0 |
| LLPS-Sem-0691 | Selaginella moellendorffii | 34.44 | 3e-07 | 50.1 |
| LLPS-Cym-0312 | Cyanidioschyzon merolae | 33.33 | 2e-10 | 60.8 |
| LLPS-Gor-0095 | Gossypium raimondii | 32.99 | 8e-08 | 53.1 |
| LLPS-Abg-1285 | Absidia glauca | 32.58 | 2e-06 | 47.4 |
| LLPS-Brd-1081 | Brachypodium distachyon | 31.96 | 3e-09 | 56.6 |
| LLPS-Zem-1481 | Zea mays | 31.96 | 4e-08 | 53.9 |
| LLPS-Sob-1280 | Sorghum bicolor | 31.96 | 6e-08 | 53.1 |
| LLPS-Hov-1677 | Hordeum vulgare | 31.91 | 4e-08 | 54.7 |
| LLPS-Pot-1630 | Populus trichocarpa | 31.91 | 7e-09 | 55.8 |
| LLPS-Viv-2499 | Vitis vinifera | 31.31 | 1e-06 | 49.7 |
| LLPS-Orgl-1949 | Oryza glumaepatula | 30.93 | 3e-08 | 53.5 |
| LLPS-Met-0032 | Medicago truncatula | 30.93 | 5e-08 | 53.5 |
| LLPS-Cus-0615 | Cucumis sativus | 30.93 | 2e-08 | 55.1 |
| LLPS-Sei-1365 | Setaria italica | 30.93 | 3e-07 | 51.6 |
| LLPS-Ori-0130 | Oryza indica | 30.93 | 7e-08 | 53.5 |
| LLPS-Orb-1273 | Oryza barthii | 30.93 | 4e-08 | 53.5 |
| LLPS-Orni-0766 | Oryza nivara | 30.93 | 4e-08 | 53.5 |
| LLPS-Thc-1500 | Theobroma cacao | 30.93 | 4e-09 | 56.6 |
| LLPS-Prp-0810 | Prunus persica | 30.93 | 6e-08 | 53.5 |
| LLPS-Orm-0117 | Oryza meridionalis | 30.93 | 2e-07 | 52.4 |
| LLPS-Orr-1296 | Oryza rufipogon | 30.93 | 4e-08 | 53.5 |
| LLPS-Org-0557 | Oryza glaberrima | 30.93 | 1e-07 | 52.8 |
| LLPS-Ors-0385 | Oryza sativa | 30.93 | 1e-07 | 52.8 |
| LLPS-Amt-0446 | Amborella trichopoda | 30.93 | 2e-07 | 52.8 |
| LLPS-Orbr-1800 | Oryza brachyantha | 30.93 | 1e-07 | 52.8 |
| LLPS-Tra-2197 | Triticum aestivum | 30.85 | 3e-08 | 54.3 |
| LLPS-Tru-1654 | Triticum urartu | 30.85 | 1e-07 | 52.4 |
| LLPS-Bro-2028 | Brassica oleracea | 30.85 | 3e-07 | 51.6 |
| LLPS-Mae-1701 | Manihot esculenta | 30.85 | 1e-07 | 52.8 |
| LLPS-Cae-1735 | Caenorhabditis elegans | 30.56 | 1e-07 | 52.0 |
| LLPS-Orp-0920 | Oryza punctata | 30.48 | 3e-08 | 53.9 |
| LLPS-Php-2274 | Physcomitrella patens | 30.3 | 1e-07 | 53.1 |
| LLPS-Glm-0087 | Glycine max | 29.9 | 4e-07 | 51.2 |
| LLPS-Dac-0793 | Daucus carota | 29.9 | 2e-07 | 52.0 |
| LLPS-Hea-0788 | Helianthus annuus | 29.9 | 8e-08 | 52.8 |
| LLPS-Sot-1915 | Solanum tuberosum | 29.79 | 3e-08 | 53.9 |
| LLPS-Arl-2741 | Arabidopsis lyrata | 29.79 | 6e-07 | 50.4 |
| LLPS-Brn-3261 | Brassica napus | 29.79 | 6e-07 | 50.4 |
| LLPS-Sol-2314 | Solanum lycopersicum | 29.79 | 4e-08 | 53.9 |
| LLPS-Brr-0916 | Brassica rapa | 29.79 | 7e-07 | 50.1 |
| LLPS-Art-1995 | Arabidopsis thaliana | 29.79 | 8e-07 | 50.1 |
| LLPS-Mua-0472 | Musa acuminata | 29.32 | 2e-07 | 51.6 |