LLPS-Mum-1623
Ddx31
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Probable ATP-dependent RNA helicase DDX31; DEAD box protein 31 |
| Gene Name: | Ddx31 |
| Ensembl Gene: | ENSMUSG00000026806.15 |
| Ensembl Protein: | ENSMUSP00000109484.2 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|
▼ FUNCTION
| Probable ATP-dependent RNA helicase (By similarity). Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000113853.2 | ENSMUSP00000109484.2 |
| UniProt | Q6NZQ2, DDX31_MOUSE, A2AIT3, A3KMM3, Q3TLT4 | |
| GeneBank | CH466542, AL732526, BC066017, AK166327, BC132351 | AAI32352.2, AAH66017.2, BAE38708.1, EDL08399.1 |
| RefSeq | NM_001033294.3 | NP_001028466.2 |
| Entrez | 227674 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKRQAEATKR KHQVSSDAPP AKRRSEISSV LAKKASDKET QRTFKGSTHK TFPPKKYLDS 60 61 IGNGRQEEKP CIKTSSLFKN NPEIPELHST VVKQAREQVF SPEAFQELDL HPHLISTINT 120 121 VLKMSSMTSV QKQSIPVLLE GRDALVRSQT GSGKTLAYCV PVVQSLQALT SKIQRSDGPY 180 181 ALVLVPTREL ALQSFDTVQK LLKPFTWIVP GVLMGGEKRK SEKARLRKGI NILISTPGRL 240 241 VDHIKSTKNL HFNRIRWLIV DEADRILDLG FEKDITVILN AVNAECQKRQ NVLLSATLTE 300 301 GVTRLVDISL HNPVSISVLD KNCNQPNPKE VASIQLNSFA IPESLDQHVV LVPSKLRLVC 360 361 LAAFILQKCK FEKNQKMIVF FSSCELVEFH YSLFLHTLLC HSGTPTSEHL PSASWPLKFL 420 421 RLHGNMEQEE RTSVFHEFSH SETGVLLCTD VASRGLDLPQ VTWIVQYSAP SSPAEYIHRI 480 481 GRTARIGCHG SSLLILAPSE AEYVNSLASH KINVGEIKME DILAVLAKDD CFKRRQRGAQ 540 541 KSRASGPQEI RERATVLQTV FEDYVHSSQR MVSWAKKALQ SFIRAYATYP KELKSIFHVR 600 601 ALHLGHVAKS FGLRDAPRNL SVSAVKKASL KRPHPRRKTQ RKQHLVPAEV LHSEHSSGLE 660 661 GGATKCRKQG KQQGLQVAPS KPGPWRE 687 |
| Nucleotide CDS Sequence (FASTA) |
1 Sequence u navailable 20 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Golgi apparatus | |
Cellular Component | Intracellular membrane-bounded organelle | |
Cellular Component | Nucleolus | |
Molecular Function | ATP binding | |
Molecular Function | Helicase activity | |
Molecular Function | RNA binding | |
Biological Process | Ribosome biogenesis |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ran-0947 | Rattus norvegicus | 92.24 | 0.0 | 1301 |
| LLPS-Eqc-1846 | Equus caballus | 85.35 | 0.0 | 953 |
| LLPS-Mea-0337 | Mesocricetus auratus | 84.53 | 0.0 | 1068 |
| LLPS-Otg-0415 | Otolemur garnettii | 81.39 | 0.0 | 1046 |
| LLPS-Maf-1079 | Macaca fascicularis | 80.35 | 0.0 | 1106 |
| LLPS-Fud-0423 | Fukomys damarensis | 80.26 | 0.0 | 1111 |
| LLPS-Mal-0103 | Mandrillus leucophaeus | 80.2 | 0.0 | 1102 |
| LLPS-Mam-3111 | Macaca mulatta | 80.2 | 0.0 | 1105 |
| LLPS-Man-0072 | Macaca nemestrina | 80.2 | 0.0 | 1108 |
| LLPS-Pap-2037 | Pan paniscus | 80.2 | 0.0 | 1103 |
| LLPS-Pat-0409 | Pan troglodytes | 80.2 | 0.0 | 1103 |
| LLPS-Nol-1102 | Nomascus leucogenys | 79.91 | 0.0 | 1095 |
| LLPS-Dio-0195 | Dipodomys ordii | 79.82 | 0.0 | 1081 |
| LLPS-Paa-2960 | Papio anubis | 79.77 | 0.0 | 1097 |
| LLPS-Chs-2689 | Chlorocebus sabaeus | 79.77 | 0.0 | 1099 |
| LLPS-Loa-0478 | Loxodonta africana | 79.77 | 0.0 | 1107 |
| LLPS-Gog-0168 | Gorilla gorilla | 79.62 | 0.0 | 1095 |
| LLPS-Hos-0480 | Homo sapiens | 79.62 | 0.0 | 1092 |
| LLPS-Aim-1834 | Ailuropoda melanoleuca | 79.06 | 0.0 | 1076 |
| LLPS-Mup-1112 | Mustela putorius furo | 78.89 | 0.0 | 1077 |
| LLPS-Orc-0936 | Oryctolagus cuniculus | 77.79 | 0.0 | 1051 |
| LLPS-Rhb-0772 | Rhinopithecus bieti | 77.75 | 0.0 | 1054 |
| LLPS-Tut-0448 | Tursiops truncatus | 77.01 | 0.0 | 1069 |
| LLPS-Ova-1622 | Ovis aries | 76.57 | 0.0 | 1060 |
| LLPS-Cap-0115 | Cavia porcellus | 76.56 | 0.0 | 1050 |
| LLPS-Bot-0233 | Bos taurus | 76.25 | 0.0 | 1072 |
| LLPS-Cas-2584 | Carlito syrichta | 76.01 | 0.0 | 1039 |
| LLPS-Caj-2037 | Callithrix jacchus | 75.29 | 0.0 | 1021 |
| LLPS-Urm-1254 | Ursus maritimus | 75.15 | 0.0 | 996 |
| LLPS-Ict-0784 | Ictidomys tridecemlineatus | 74.64 | 0.0 | 1019 |
| LLPS-Sus-1575 | Sus scrofa | 74.63 | 0.0 | 1016 |
| LLPS-Mod-2080 | Monodelphis domestica | 74.56 | 0.0 | 1011 |
| LLPS-Sah-0260 | Sarcophilus harrisii | 74.05 | 0.0 | 995 |
| LLPS-Ora-0342 | Ornithorhynchus anatinus | 73.39 | 0.0 | 906 |
| LLPS-Aon-0716 | Aotus nancymaae | 72.73 | 0.0 | 969 |
| LLPS-Fec-0747 | Felis catus | 72.06 | 0.0 | 944 |
| LLPS-Myl-2199 | Myotis lucifugus | 70.73 | 0.0 | 967 |
| LLPS-Cea-1542 | Cercocebus atys | 70.38 | 0.0 | 925 |
| LLPS-Gaga-1010 | Gallus gallus | 68.6 | 0.0 | 616 |
| LLPS-Tag-2688 | Taeniopygia guttata | 68.3 | 0.0 | 853 |
| LLPS-Pes-0399 | Pelodiscus sinensis | 67.06 | 0.0 | 898 |
| LLPS-Fia-0247 | Ficedula albicollis | 65.63 | 0.0 | 863 |
| LLPS-Meg-0027 | Meleagris gallopavo | 65.19 | 0.0 | 840 |
| LLPS-Anp-1794 | Anas platyrhynchos | 65.08 | 0.0 | 855 |
| LLPS-Scf-1249 | Scleropages formosus | 62.3 | 0.0 | 760 |
| LLPS-Scm-1018 | Scophthalmus maximus | 61.43 | 0.0 | 689 |
| LLPS-Orn-2679 | Oreochromis niloticus | 60.69 | 0.0 | 739 |
| LLPS-Xet-0921 | Xenopus tropicalis | 60.54 | 0.0 | 741 |
| LLPS-Dar-1564 | Danio rerio | 60.35 | 0.0 | 741 |
| LLPS-Lac-0625 | Latimeria chalumnae | 59.5 | 0.0 | 599 |
| LLPS-Xim-0502 | Xiphophorus maculatus | 58.33 | 0.0 | 712 |
| LLPS-Asm-1922 | Astyanax mexicanus | 58.32 | 0.0 | 654 |
| LLPS-Orl-0850 | Oryzias latipes | 58.04 | 0.0 | 696 |
| LLPS-Pof-1771 | Poecilia formosa | 57.57 | 0.0 | 711 |
| LLPS-Icp-1690 | Ictalurus punctatus | 57.21 | 0.0 | 746 |
| LLPS-Gaa-1908 | Gasterosteus aculeatus | 56.99 | 2e-102 | 320 |
| LLPS-Ten-0500 | Tetraodon nigroviridis | 56.73 | 0.0 | 696 |
| LLPS-Leo-0239 | Lepisosteus oculatus | 55.26 | 0.0 | 702 |
| LLPS-Tar-2580 | Takifugu rubripes | 54.12 | 0.0 | 690 |
| LLPS-Cii-0798 | Ciona intestinalis | 47.37 | 2e-162 | 489 |
| LLPS-Cis-1288 | Ciona savignyi | 45.45 | 2e-148 | 449 |
| LLPS-Hea-0176 | Helianthus annuus | 42.76 | 1e-137 | 423 |
| LLPS-Met-1641 | Medicago truncatula | 42.61 | 2e-140 | 431 |
| LLPS-Sem-0573 | Selaginella moellendorffii | 42.25 | 1e-137 | 422 |
| LLPS-Arl-1810 | Arabidopsis lyrata | 42.04 | 3e-128 | 400 |
| LLPS-Glm-0855 | Glycine max | 41.82 | 9e-132 | 407 |
| LLPS-Viv-0861 | Vitis vinifera | 41.75 | 3e-136 | 420 |
| LLPS-Prp-0700 | Prunus persica | 41.67 | 6e-127 | 396 |
| LLPS-Php-0626 | Physcomitrella patens | 41.59 | 2e-134 | 417 |
| LLPS-Phv-0627 | Phaseolus vulgaris | 41.58 | 5e-130 | 404 |
| LLPS-Put-0786 | Puccinia triticina | 41.35 | 1e-87 | 291 |
| LLPS-Art-0743 | Arabidopsis thaliana | 41.08 | 3e-125 | 392 |
| LLPS-Sot-0027 | Solanum tuberosum | 40.96 | 1e-133 | 414 |
| LLPS-Gor-1184 | Gossypium raimondii | 40.82 | 2e-132 | 410 |
| LLPS-Coc-0552 | Corchorus capsularis | 40.81 | 2e-120 | 378 |
| LLPS-Dac-0991 | Daucus carota | 40.64 | 1e-125 | 392 |
| LLPS-Brn-0320 | Brassica napus | 40.58 | 7e-126 | 396 |
| LLPS-Orbr-0563 | Oryza brachyantha | 40.53 | 4e-116 | 368 |
| LLPS-Drm-0504 | Drosophila melanogaster | 40.52 | 1e-135 | 430 |
| LLPS-Thc-0275 | Theobroma cacao | 40.47 | 1e-133 | 413 |
| LLPS-Brr-0157 | Brassica rapa | 40.41 | 2e-126 | 395 |
| LLPS-Pot-1300 | Populus trichocarpa | 40.17 | 1e-130 | 405 |
| LLPS-Tra-1427 | Triticum aestivum | 40.11 | 7e-125 | 391 |
| LLPS-Lep-0122 | Leersia perrieri | 40.07 | 2e-123 | 387 |
| LLPS-Amt-0577 | Amborella trichopoda | 40.0 | 2e-127 | 399 |
| LLPS-Mae-1015 | Manihot esculenta | 39.97 | 7e-131 | 406 |
| LLPS-Bro-0445 | Brassica oleracea | 39.86 | 3e-124 | 392 |
| LLPS-Osl-0519 | Ostreococcus lucimarinus | 39.67 | 1e-122 | 384 |
| LLPS-Orb-1383 | Oryza barthii | 39.39 | 2e-123 | 387 |
| LLPS-Org-0124 | Oryza glaberrima | 39.39 | 2e-123 | 387 |
| LLPS-Orgl-0614 | Oryza glumaepatula | 39.32 | 2e-123 | 387 |
| LLPS-Ori-0153 | Oryza indica | 39.32 | 2e-123 | 387 |
| LLPS-Orni-0420 | Oryza nivara | 39.32 | 2e-123 | 387 |
| LLPS-Orr-1033 | Oryza rufipogon | 39.32 | 2e-123 | 387 |
| LLPS-Ors-0175 | Oryza sativa | 39.32 | 2e-123 | 387 |
| LLPS-Sob-0786 | Sorghum bicolor | 39.32 | 3e-122 | 384 |
| LLPS-Brd-1040 | Brachypodium distachyon | 39.29 | 2e-127 | 397 |
| LLPS-Orm-0858 | Oryza meridionalis | 39.21 | 1e-122 | 385 |
| LLPS-Sei-1611 | Setaria italica | 39.05 | 4e-124 | 389 |
| LLPS-Tru-0997 | Triticum urartu | 38.95 | 1e-113 | 362 |
| LLPS-Nia-0052 | Nicotiana attenuata | 38.93 | 8e-102 | 327 |
| LLPS-Mua-0076 | Musa acuminata | 38.72 | 3e-120 | 378 |
| LLPS-Hov-0206 | Hordeum vulgare | 38.01 | 5e-119 | 377 |
| LLPS-Cus-0673 | Cucumis sativus | 37.94 | 1e-93 | 305 |
| LLPS-Scc-0792 | Schizosaccharomyces cryophilus | 37.83 | 8e-107 | 347 |
| LLPS-Chc-0291 | Chondrus crispus | 36.98 | 5e-110 | 358 |
| LLPS-Mel-0406 | Melampsora laricipopulina | 36.98 | 7e-95 | 314 |
| LLPS-Asni-0252 | Aspergillus niger | 36.79 | 2e-104 | 342 |
| LLPS-Miv-0015 | Microbotryum violaceum | 36.75 | 2e-98 | 323 |
| LLPS-Pug-0906 | Puccinia graminis | 36.7 | 7e-94 | 311 |
| LLPS-Nef-0970 | Neosartorya fischeri | 36.66 | 3e-108 | 352 |
| LLPS-Scp-0524 | Schizosaccharomyces pombe | 36.41 | 3e-105 | 343 |
| LLPS-Asn-0286 | Aspergillus nidulans | 36.33 | 6e-102 | 336 |
| LLPS-Asfu-0480 | Aspergillus fumigatus | 36.29 | 2e-109 | 355 |
| LLPS-Cae-0110 | Caenorhabditis elegans | 36.27 | 1e-87 | 291 |
| LLPS-Blg-0617 | Blumeria graminis | 36.14 | 5e-109 | 357 |
| LLPS-Yal-0103 | Yarrowia lipolytica | 36.02 | 6e-98 | 325 |
| LLPS-Orp-1622 | Oryza punctata | 35.99 | 8e-113 | 360 |
| LLPS-Aso-0047 | Aspergillus oryzae | 35.97 | 3e-102 | 336 |
| LLPS-Asf-0632 | Aspergillus flavus | 35.97 | 3e-102 | 336 |
| LLPS-Asg-1322 | Ashbya gossypii | 35.8 | 9e-93 | 310 |
| LLPS-Crn-0344 | Cryptococcus neoformans | 35.76 | 3e-95 | 311 |
| LLPS-Asc-0131 | Aspergillus clavatus | 35.75 | 2e-106 | 347 |
| LLPS-Scj-0939 | Schizosaccharomyces japonicus | 35.7 | 2e-101 | 333 |
| LLPS-Ast-1162 | Aspergillus terreus | 35.67 | 5e-103 | 345 |
| LLPS-Scs-0463 | Sclerotinia sclerotiorum | 35.6 | 3e-104 | 344 |
| LLPS-Caf-2973 | Canis familiaris | 35.54 | 1e-89 | 300 |
| LLPS-Abg-0482 | Absidia glauca | 35.39 | 1e-91 | 301 |
| LLPS-Poa-1699 | Pongo abelii | 35.34 | 7e-89 | 297 |
| LLPS-Dos-0083 | Dothistroma septosporum | 35.31 | 4e-89 | 293 |
| LLPS-Anc-0344 | Anolis carolinensis | 35.2 | 1e-87 | 295 |
| LLPS-Mao-1049 | Magnaporthe oryzae | 35.13 | 5e-90 | 299 |
| LLPS-Fuv-0191 | Fusarium verticillioides | 35.01 | 3e-89 | 296 |
| LLPS-Fuo-0091 | Fusarium oxysporum | 35.01 | 3e-89 | 297 |
| LLPS-Zyt-0852 | Zymoseptoria tritici | 34.86 | 2e-101 | 333 |
| LLPS-Ved-0696 | Verticillium dahliae | 34.84 | 9e-94 | 314 |
| LLPS-Nec-0762 | Neurospora crassa | 34.75 | 1e-88 | 295 |
| LLPS-Fus-0376 | Fusarium solani | 34.62 | 2e-87 | 292 |
| LLPS-Kop-0218 | Komagataella pastoris | 34.61 | 3e-88 | 293 |
| LLPS-Map-0305 | Magnaporthe poae | 34.49 | 9e-88 | 293 |
| LLPS-Pytr-1026 | Pyrenophora triticirepentis | 34.19 | 9e-95 | 318 |
| LLPS-Cog-0570 | Colletotrichum gloeosporioides | 34.13 | 1e-93 | 313 |
| LLPS-Gag-0440 | Gaeumannomyces graminis | 34.08 | 9e-87 | 291 |
| LLPS-Sac-0437 | Saccharomyces cerevisiae | 33.97 | 8e-93 | 304 |
| LLPS-Lem-0184 | Leptosphaeria maculans | 33.78 | 2e-92 | 311 |
| LLPS-Beb-0895 | Beauveria bassiana | 33.63 | 3e-87 | 291 |
| LLPS-Coo-0135 | Colletotrichum orbiculare | 33.48 | 8e-97 | 326 |
| LLPS-Trv-0630 | Trichoderma virens | 33.39 | 7e-91 | 305 |
| LLPS-Trr-0099 | Trichoderma reesei | 33.28 | 1e-90 | 305 |
| LLPS-Cogr-0226 | Colletotrichum graminicola | 33.22 | 1e-93 | 313 |
| LLPS-Pyt-0011 | Pyrenophora teres | 32.79 | 1e-94 | 317 |
| LLPS-Phn-0069 | Phaeosphaeria nodorum | 32.24 | 7e-89 | 302 |