LLPS-Mum-0697
Arl6ip4
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | ADP-ribosylation factor-like protein 6-interacting protein 4 |
| Gene Name: | Arl6ip4 |
| Ensembl Gene: | ENSMUSG00000029404.15 |
| Ensembl Protein: | ENSMUSP00000122377.1 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|
▼ FUNCTION
| Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000145667.1 | ENSMUSP00000122377.1 |
| Ensembl | ENSMUST00000031351.10 | ENSMUSP00000031351.4 |
| Ensembl | ENSMUST00000196401.1 | ENSMUSP00000142496.1 |
| Ensembl | ENSMUST00000122394.7 | ENSMUSP00000112506.1 |
| Ensembl | ENSMUST00000149835.1 | ENSMUSP00000116269.1 |
| UniProt | Q9JM93, AR6P4_MOUSE, Q9WUG8 | |
| GeneBank | AF133911, BC063748, AK133934, AB035383 | AAH63748.1, BAE21935.1, BAA94743.1, AAD33049.1 |
| RefSeq | NM_144509.2 | NP_653092.1 |
| Entrez | 65105 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAHVGSRKRS RSRSRSRSGR RGSEKRSKRS SKDASRNCSA SRSQGHKAGS ASGVEERSKH 60 61 KAQRTSRSSS TSSSSSSSSS ASSSSSSDGR KKRAKHKEKK RKKKKKKRKK KLKKRVKEKA 120 121 VAVHQAEALP GPSLDQWHRS AGEDNDGPVL TDEQKSRIQA MKPMTKEEWD ARQSVIRKVV 180 181 DPETGRTRLI KGDGEVLEEI VTKERHREIN KQATRGDGLA FQMRTGLLP 229 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTCACG TTGGCTCTCG AAAGCGCTCG AGAAGTCGCA GTCGGTCCCG TAGTGGTCGG 60 61 CGAGGGTCAG AAAAGCGAAG TAAGAGGAGT AGCAAGGATG CCTCGAGGAA CTGTTCAGCC 120 121 TCCAGATCCC AGGGCCACAA GGCTGGCAGC GCCTCCGGGG TTGAGGAGAG AAGCAAGCAC 180 181 AAGGCCCAGA GGACATCGCG ATCCAGTTCA ACCTCCTCCT CTTCCAGTTC TTCTAGCTCC 240 241 GCCTCGTCCT CATCCTCCAG TGATGGCCGG AAGAAGCGAG CGAAGCACAA GGAGAAGAAG 300 301 AGGAAGAAGA AGAAGAAGAA ACGGAAGAAG AAGTTGAAGA AGAGAGTCAA GGAGAAGGCA 360 361 GTGGCGGTGC ACCAGGCCGA GGCTCTGCCC GGCCCCTCAC TGGATCAGTG GCACAGATCA 420 421 GCTGGGGAGG ACAATGATGG CCCAGTCCTG ACAGATGAGC AGAAGTCTCG TATCCAGGCC 480 481 ATGAAACCCA TGACAAAGGA GGAGTGGGAT GCCCGACAGA GCGTTATTCG AAAGGTGGTG 540 541 GACCCAGAGA CAGGACGCAC AAGGCTCATC AAGGGAGACG GCGAGGTTTT AGAGGAAATC 600 601 GTAACCAAAG AACGACACAG AGAGATCAAC AAGCAAGCCA CCCGAGGGGA TGGGCTGGCC 660 661 TTCCAGATGC GAACAGGCCT ACTTCCCTGA 690 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nuclear speck | |
Cellular Component | Nucleolus | |
Biological Process | MRNA processing | |
Biological Process | RNA splicing |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | CellMarker | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Dio-0707 | Dipodomys ordii | 95.33 | 6e-67 | 211 |
| LLPS-Caj-2660 | Callithrix jacchus | 95.28 | 1e-66 | 212 |
| LLPS-Cas-0620 | Carlito syrichta | 95.24 | 9e-67 | 212 |
| LLPS-Sus-3782 | Sus scrofa | 94.39 | 2e-66 | 212 |
| LLPS-Ict-3284 | Ictidomys tridecemlineatus | 94.39 | 6e-66 | 210 |
| LLPS-Loa-1971 | Loxodonta africana | 94.39 | 7e-67 | 213 |
| LLPS-Fec-2704 | Felis catus | 94.39 | 4e-66 | 211 |
| LLPS-Rhb-2959 | Rhinopithecus bieti | 93.75 | 2e-33 | 129 |
| LLPS-Cea-0359 | Cercocebus atys | 93.58 | 5e-65 | 213 |
| LLPS-Gog-3890 | Gorilla gorilla | 93.46 | 2e-64 | 213 |
| LLPS-Aon-0581 | Aotus nancymaae | 93.46 | 5e-66 | 210 |
| LLPS-Poa-4251 | Pongo abelii | 93.46 | 3e-64 | 211 |
| LLPS-Pat-3497 | Pan troglodytes | 93.46 | 2e-64 | 212 |
| LLPS-Paa-0050 | Papio anubis | 93.4 | 2e-65 | 208 |
| LLPS-Caf-2197 | Canis familiaris | 93.4 | 1e-64 | 208 |
| LLPS-Maf-2314 | Macaca fascicularis | 92.66 | 4e-65 | 212 |
| LLPS-Mam-0546 | Macaca mulatta | 92.66 | 2e-64 | 211 |
| LLPS-Man-1799 | Macaca nemestrina | 92.66 | 1e-64 | 211 |
| LLPS-Ova-1829 | Ovis aries | 92.52 | 7e-64 | 207 |
| LLPS-Bot-1069 | Bos taurus | 92.52 | 2e-65 | 209 |
| LLPS-Pap-0906 | Pan paniscus | 92.52 | 6e-64 | 211 |
| LLPS-Hos-2715 | Homo sapiens | 92.52 | 2e-63 | 209 |
| LLPS-Tut-0934 | Tursiops truncatus | 92.13 | 1e-49 | 173 |
| LLPS-Mup-0691 | Mustela putorius furo | 91.74 | 4e-65 | 210 |
| LLPS-Fud-3073 | Fukomys damarensis | 91.74 | 1e-65 | 210 |
| LLPS-Chs-0880 | Chlorocebus sabaeus | 91.74 | 8e-65 | 211 |
| LLPS-Ran-0515 | Rattus norvegicus | 89.8 | 5e-81 | 249 |
| LLPS-Cap-2183 | Cavia porcellus | 87.16 | 3e-62 | 201 |
| LLPS-Ere-0371 | Erinaceus europaeus | 87.13 | 2e-50 | 173 |
| LLPS-Anc-2518 | Anolis carolinensis | 85.29 | 1e-53 | 178 |
| LLPS-Nol-1431 | Nomascus leucogenys | 85.05 | 3e-53 | 177 |
| LLPS-Mea-0475 | Mesocricetus auratus | 84.77 | 1e-71 | 224 |
| LLPS-Meg-1824 | Meleagris gallopavo | 84.47 | 1e-53 | 177 |
| LLPS-Ora-1789 | Ornithorhynchus anatinus | 84.31 | 2e-54 | 181 |
| LLPS-Fia-2346 | Ficedula albicollis | 83.65 | 1e-54 | 181 |
| LLPS-Anp-0267 | Anas platyrhynchos | 83.65 | 2e-55 | 182 |
| LLPS-Sah-0018 | Sarcophilus harrisii | 83.5 | 6e-53 | 178 |
| LLPS-Tag-2769 | Taeniopygia guttata | 83.5 | 7e-54 | 179 |
| LLPS-Gaga-0589 | Gallus gallus | 83.5 | 1e-53 | 179 |
| LLPS-Eqc-0106 | Equus caballus | 79.6 | 3e-68 | 216 |
| LLPS-Xet-2075 | Xenopus tropicalis | 77.45 | 2e-48 | 165 |
| LLPS-Urm-1250 | Ursus maritimus | 76.12 | 1e-71 | 225 |
| LLPS-Lac-0844 | Latimeria chalumnae | 74.75 | 3e-45 | 157 |
| LLPS-Drm-0870 | Drosophila melanogaster | 71.43 | 5e-21 | 90.5 |
| LLPS-Ten-2906 | Tetraodon nigroviridis | 70.0 | 7e-34 | 126 |
| LLPS-Otg-3989 | Otolemur garnettii | 69.54 | 9e-57 | 188 |
| LLPS-Icp-1999 | Ictalurus punctatus | 69.23 | 2e-25 | 105 |
| LLPS-Xim-3159 | Xiphophorus maculatus | 67.9 | 1e-33 | 125 |
| LLPS-Pof-2966 | Poecilia formosa | 67.9 | 3e-34 | 128 |
| LLPS-Cii-1205 | Ciona intestinalis | 67.65 | 1e-24 | 101 |
| LLPS-Tar-0315 | Takifugu rubripes | 66.67 | 9e-33 | 124 |
| LLPS-Aim-1070 | Ailuropoda melanoleuca | 65.07 | 2e-55 | 185 |
| LLPS-Leo-1823 | Lepisosteus oculatus | 63.64 | 3e-37 | 137 |
| LLPS-Asm-1918 | Astyanax mexicanus | 62.77 | 1e-32 | 127 |
| LLPS-Dar-1148 | Danio rerio | 61.39 | 8e-36 | 132 |
| LLPS-Scm-0133 | Scophthalmus maximus | 61.22 | 2e-35 | 132 |
| LLPS-Scf-1180 | Scleropages formosus | 60.2 | 1e-35 | 132 |
| LLPS-Orn-0402 | Oreochromis niloticus | 59.18 | 6e-35 | 129 |
| LLPS-Gaa-2127 | Gasterosteus aculeatus | 58.51 | 5e-32 | 122 |
| LLPS-Orl-2110 | Oryzias latipes | 58.25 | 2e-35 | 132 |