LLPS-Mum-0155
Pop4
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Ribonuclease P protein subunit p29 |
| Gene Name: | Pop4, Rpp29 |
| Ensembl Gene: | ENSMUSG00000030423.7 |
| Ensembl Protein: | ENSMUSP00000145810.1 |
| Organism: | Mus musculus |
| Taxa ID: | 10090 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| TAM body | Predicted from orthologs | N/A | (View) |
▼ FUNCTION
| Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMUST00000206221.1 | ENSMUSP00000145810.1 |
| Ensembl | ENSMUST00000205753.1 | ENSMUSP00000146119.1 |
| Ensembl | ENSMUST00000032585.7 | ENSMUSP00000032585.6 |
| Ensembl | ENSMUST00000205899.1 | ENSMUSP00000146204.1 |
| UniProt | Q9CR08, RPP29_MOUSE, Q3U6V7 | |
| GeneBank | AK002855, BC011465, AK003293, AK152948, AK150459 | BAE31617.1, AAH11465.1, BAB22696.1, BAE29579.1, BAB22410.1 |
| RefSeq | NM_025390.4 | NP_079666.1 |
| Entrez | 66161 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKAAIYHAFS HKEAKDHDVQ ELGSQRAEAF VRAFLKQSIP HMSQEDCESH LQRKAVILEY 60 61 FTRLKPRPRP KKKSKGLSAK QRRDMRLFDI KPEQQRYSLF LPLHELWKQY IRDLCNGLKP 120 121 DTQPQMIQAK LLKADLHGAI ISVTKSKCPS YVGVTGILLQ ETKHVFKIIT REDHLKVIPK 180 181 LNCVFTIEID DFISYIYGSK FQLRASERSA KKFKAKGSID L 221 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAAGGCTG CCATCTACCA TGCCTTTTCT CATAAAGAAG CCAAGGACCA CGATGTGCAG 60 61 GAGCTGGGAA GCCAGCGGGC TGAGGCCTTT GTGCGGGCCT TCCTGAAGCA GAGCATACCT 120 121 CACATGAGCC AAGAAGACTG TGAGAGCCAT CTGCAGCGCA AGGCCGTGAT CTTGGAATAT 180 181 TTCACTCGCC TAAAGCCAAG GCCAAGGCCA AAGAAGAAAT CCAAAGGCCT CTCTGCCAAA 240 241 CAGAGGAGAG ACATGCGGCT CTTTGACATT AAACCAGAGC AACAGAGATA CAGCCTGTTC 300 301 CTCCCTCTCC ATGAACTCTG GAAACAGTAC ATCCGGGACC TGTGCAATGG GCTCAAGCCG 360 361 GACACGCAGC CACAGATGAT TCAGGCCAAG CTCCTAAAGG CAGATCTTCA TGGTGCTATT 420 421 ATTTCAGTCA CGAAATCCAA GTGCCCCTCC TATGTGGGAG TTACAGGAAT CCTTCTGCAG 480 481 GAGACCAAAC ATGTCTTTAA GATCATCACC AGAGAAGACC ACCTAAAAGT CATCCCCAAG 540 541 CTGAATTGTG TGTTCACCAT AGAAATTGAT GACTTCATTT CCTACATTTA TGGAAGCAAA 600 601 TTCCAGCTTC GGGCAAGTGA GCGGTCTGCC AAGAAGTTCA AAGCAAAGGG ATCAATTGAC 660 661 CTGTGA 666 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Multimeric ribonuclease P complex | |
Cellular Component | Nucleolus | |
Cellular Component | Ribonuclease MRP complex | |
Cellular Component | Ribonuclease P complex | |
Molecular Function | Ribonuclease P activity | |
Molecular Function | Ribonuclease P RNA binding | |
Biological Process | RRNA processing | |
Biological Process | TRNA 5'-leader removal |
▼ ANNOTATION
| Mutation | ||||
| CGAP | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | PIRSF | CellMarker | ||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | GXD | TISSUES | ||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ran-1228 | Rattus norvegicus | 95.48 | 2e-145 | 412 |
| LLPS-Mea-2550 | Mesocricetus auratus | 89.59 | 3e-139 | 396 |
| LLPS-Orc-1316 | Oryctolagus cuniculus | 83.71 | 9e-129 | 370 |
| LLPS-Sus-1186 | Sus scrofa | 83.71 | 1e-129 | 372 |
| LLPS-Cap-0537 | Cavia porcellus | 83.26 | 5e-130 | 373 |
| LLPS-Ict-0635 | Ictidomys tridecemlineatus | 83.26 | 2e-129 | 372 |
| LLPS-Bot-1978 | Bos taurus | 83.26 | 8e-130 | 372 |
| LLPS-Otg-0531 | Otolemur garnettii | 83.11 | 3e-125 | 361 |
| LLPS-Man-0084 | Macaca nemestrina | 82.81 | 1e-126 | 364 |
| LLPS-Mam-1767 | Macaca mulatta | 82.81 | 6e-127 | 365 |
| LLPS-Cea-1189 | Cercocebus atys | 82.81 | 2e-126 | 363 |
| LLPS-Fud-0240 | Fukomys damarensis | 82.81 | 7e-131 | 375 |
| LLPS-Ora-0620 | Ornithorhynchus anatinus | 82.8 | 7e-53 | 172 |
| LLPS-Eqc-1076 | Equus caballus | 82.69 | 6e-21 | 92.8 |
| LLPS-Poa-1725 | Pongo abelii | 82.35 | 5e-127 | 365 |
| LLPS-Maf-3302 | Macaca fascicularis | 82.35 | 6e-126 | 362 |
| LLPS-Caj-1353 | Callithrix jacchus | 82.35 | 3e-125 | 360 |
| LLPS-Paa-1034 | Papio anubis | 82.35 | 6e-126 | 362 |
| LLPS-Mal-1646 | Mandrillus leucophaeus | 82.35 | 5e-126 | 362 |
| LLPS-Chs-2651 | Chlorocebus sabaeus | 82.19 | 5e-124 | 357 |
| LLPS-Ova-1749 | Ovis aries | 81.98 | 5e-127 | 365 |
| LLPS-Caf-2848 | Canis familiaris | 81.97 | 6e-104 | 305 |
| LLPS-Pap-3823 | Pan paniscus | 81.9 | 2e-126 | 363 |
| LLPS-Pat-0713 | Pan troglodytes | 81.9 | 2e-126 | 363 |
| LLPS-Fec-1007 | Felis catus | 81.9 | 4e-125 | 360 |
| LLPS-Loa-0273 | Loxodonta africana | 81.9 | 6e-126 | 362 |
| LLPS-Aon-3125 | Aotus nancymaae | 81.9 | 1e-125 | 362 |
| LLPS-Gog-1406 | Gorilla gorilla | 81.74 | 2e-124 | 358 |
| LLPS-Hos-1030 | Homo sapiens | 81.45 | 2e-125 | 361 |
| LLPS-Cas-2804 | Carlito syrichta | 81.45 | 7e-127 | 365 |
| LLPS-Dio-2415 | Dipodomys ordii | 80.81 | 4e-95 | 282 |
| LLPS-Tut-1051 | Tursiops truncatus | 80.09 | 2e-125 | 361 |
| LLPS-Mup-1499 | Mustela putorius furo | 80.09 | 8e-123 | 354 |
| LLPS-Rhb-1526 | Rhinopithecus bieti | 78.98 | 1e-89 | 269 |
| LLPS-Urm-2028 | Ursus maritimus | 78.73 | 1e-122 | 354 |
| LLPS-Aim-2334 | Ailuropoda melanoleuca | 78.54 | 8e-121 | 349 |
| LLPS-Mod-1157 | Monodelphis domestica | 75.69 | 7e-117 | 340 |
| LLPS-Sah-1987 | Sarcophilus harrisii | 74.65 | 8e-112 | 327 |
| LLPS-Anp-0839 | Anas platyrhynchos | 71.21 | 5e-97 | 288 |
| LLPS-Tag-0259 | Taeniopygia guttata | 70.85 | 6e-97 | 288 |
| LLPS-Pes-0286 | Pelodiscus sinensis | 69.68 | 1e-103 | 307 |
| LLPS-Anc-0655 | Anolis carolinensis | 68.09 | 3e-15 | 72.0 |
| LLPS-Xet-1665 | Xenopus tropicalis | 66.82 | 3e-98 | 292 |
| LLPS-Fia-2784 | Ficedula albicollis | 66.36 | 4e-96 | 286 |
| LLPS-Gaga-3649 | Gallus gallus | 64.71 | 3e-97 | 290 |
| LLPS-Leo-1495 | Lepisosteus oculatus | 64.71 | 1e-97 | 290 |
| LLPS-Meg-2556 | Meleagris gallopavo | 64.38 | 9e-97 | 288 |
| LLPS-Dar-0673 | Danio rerio | 64.1 | 2e-86 | 262 |
| LLPS-Scm-0152 | Scophthalmus maximus | 63.82 | 3e-85 | 259 |
| LLPS-Scf-0733 | Scleropages formosus | 63.55 | 7e-88 | 266 |
| LLPS-Myl-3095 | Myotis lucifugus | 63.18 | 2e-91 | 275 |
| LLPS-Nol-2096 | Nomascus leucogenys | 62.5 | 3e-29 | 110 |
| LLPS-Lac-2125 | Latimeria chalumnae | 62.39 | 2e-92 | 277 |
| LLPS-Pof-1685 | Poecilia formosa | 61.73 | 2e-80 | 247 |
| LLPS-Orn-1022 | Oreochromis niloticus | 61.08 | 3e-80 | 246 |
| LLPS-Xim-2890 | Xiphophorus maculatus | 60.49 | 4e-79 | 244 |
| LLPS-Gaa-3274 | Gasterosteus aculeatus | 60.29 | 9e-80 | 245 |
| LLPS-Orl-3655 | Oryzias latipes | 59.8 | 1e-77 | 239 |
| LLPS-Asm-3028 | Astyanax mexicanus | 59.28 | 7e-89 | 268 |
| LLPS-Ten-0289 | Tetraodon nigroviridis | 58.62 | 5e-77 | 237 |
| LLPS-Icp-1049 | Ictalurus punctatus | 57.47 | 9e-86 | 260 |
| LLPS-Tar-0855 | Takifugu rubripes | 46.67 | 2e-33 | 125 |
| LLPS-Abg-1816 | Absidia glauca | 44.97 | 2e-37 | 136 |
| LLPS-Prp-1959 | Prunus persica | 42.19 | 5e-23 | 99.0 |
| LLPS-Dos-0099 | Dothistroma septosporum | 40.76 | 7e-32 | 122 |
| LLPS-Fuv-0137 | Fusarium verticillioides | 40.71 | 2e-21 | 94.0 |
| LLPS-Bro-0463 | Brassica oleracea | 40.18 | 9e-20 | 89.7 |
| LLPS-Arl-0998 | Arabidopsis lyrata | 39.25 | 1e-17 | 83.6 |
| LLPS-Brr-1092 | Brassica rapa | 39.09 | 4e-19 | 87.8 |
| LLPS-Phn-0926 | Phaeosphaeria nodorum | 38.51 | 4e-26 | 106 |
| LLPS-Blg-0050 | Blumeria graminis | 37.72 | 1e-19 | 88.6 |
| LLPS-Map-0352 | Magnaporthe poae | 37.61 | 5e-17 | 79.7 |
| LLPS-Sei-0501 | Setaria italica | 37.6 | 3e-22 | 97.1 |
| LLPS-Viv-2064 | Vitis vinifera | 37.5 | 2e-20 | 91.7 |
| LLPS-Nia-1466 | Nicotiana attenuata | 37.5 | 2e-18 | 84.7 |
| LLPS-Thc-0975 | Theobroma cacao | 37.5 | 4e-20 | 90.9 |
| LLPS-Scs-0247 | Sclerotinia sclerotiorum | 37.34 | 2e-27 | 109 |
| LLPS-Vir-1747 | Vigna radiata | 37.0 | 2e-13 | 70.1 |
| LLPS-Trr-0229 | Trichoderma reesei | 36.91 | 2e-25 | 104 |
| LLPS-Gag-0178 | Gaeumannomyces graminis | 36.88 | 4e-21 | 91.3 |
| LLPS-Sot-0974 | Solanum tuberosum | 36.8 | 1e-18 | 86.3 |
| LLPS-Zem-1852 | Zea mays | 36.72 | 4e-21 | 93.6 |
| LLPS-Glm-0390 | Glycine max | 36.72 | 4e-19 | 87.8 |
| LLPS-Hea-1031 | Helianthus annuus | 36.72 | 6e-19 | 87.0 |
| LLPS-Met-1938 | Medicago truncatula | 36.72 | 2e-20 | 91.7 |
| LLPS-Fuo-0822 | Fusarium oxysporum | 36.6 | 1e-25 | 105 |
| LLPS-Gor-1157 | Gossypium raimondii | 36.15 | 3e-21 | 94.0 |
| LLPS-Brn-0906 | Brassica napus | 36.15 | 2e-20 | 92.0 |
| LLPS-Art-2509 | Arabidopsis thaliana | 36.0 | 3e-18 | 85.1 |
| LLPS-Tra-1514 | Triticum aestivum | 36.0 | 1e-21 | 95.1 |
| LLPS-Fus-0061 | Fusarium solani | 35.95 | 2e-23 | 99.4 |
| LLPS-Sob-1311 | Sorghum bicolor | 35.94 | 1e-20 | 92.4 |
| LLPS-Mae-0201 | Manihot esculenta | 35.94 | 7e-20 | 89.7 |
| LLPS-Php-0353 | Physcomitrella patens | 35.94 | 4e-23 | 99.0 |
| LLPS-Drm-0412 | Drosophila melanogaster | 35.86 | 7e-23 | 97.1 |
| LLPS-Org-0193 | Oryza glaberrima | 35.61 | 8e-19 | 87.0 |
| LLPS-Orb-1198 | Oryza barthii | 35.61 | 2e-18 | 87.4 |
| LLPS-Scj-0078 | Schizosaccharomyces japonicus | 35.57 | 3e-19 | 87.4 |
| LLPS-Lem-0261 | Leptosphaeria maculans | 35.44 | 2e-25 | 104 |
| LLPS-Pot-1224 | Populus trichocarpa | 35.4 | 3e-16 | 80.1 |
| LLPS-Zyt-1002 | Zymoseptoria tritici | 35.4 | 3e-27 | 109 |
| LLPS-Trv-0547 | Trichoderma virens | 35.33 | 5e-24 | 100 |
| LLPS-Hov-0311 | Hordeum vulgare | 35.29 | 7e-22 | 95.9 |
| LLPS-Phv-1004 | Phaseolus vulgaris | 35.16 | 6e-20 | 90.1 |
| LLPS-Chc-0695 | Chondrus crispus | 34.96 | 4e-17 | 82.0 |
| LLPS-Cym-0753 | Cyanidioschyzon merolae | 34.93 | 9e-22 | 95.1 |
| LLPS-Mua-1244 | Musa acuminata | 34.85 | 1e-19 | 89.4 |
| LLPS-Orgl-2178 | Oryza glumaepatula | 34.85 | 2e-17 | 82.8 |
| LLPS-Nef-0248 | Neosartorya fischeri | 34.57 | 9e-23 | 97.4 |
| LLPS-Pytr-1251 | Pyrenophora triticirepentis | 34.42 | 3e-24 | 101 |
| LLPS-Orbr-0053 | Oryza brachyantha | 34.38 | 3e-19 | 88.2 |
| LLPS-Asfu-0478 | Aspergillus fumigatus | 34.38 | 3e-20 | 90.5 |
| LLPS-Dac-0077 | Daucus carota | 34.38 | 5e-18 | 84.3 |
| LLPS-Mao-0165 | Magnaporthe oryzae | 34.3 | 2e-25 | 104 |
| LLPS-Coo-0193 | Colletotrichum orbiculare | 34.21 | 9e-20 | 89.0 |
| LLPS-Pyt-0121 | Pyrenophora teres | 34.19 | 4e-25 | 103 |
| LLPS-Cog-0374 | Colletotrichum gloeosporioides | 34.18 | 3e-24 | 101 |
| LLPS-Ors-1200 | Oryza sativa | 34.11 | 2e-18 | 86.3 |
| LLPS-Orp-0227 | Oryza punctata | 34.11 | 7e-19 | 87.0 |
| LLPS-Orr-1264 | Oryza rufipogon | 34.11 | 4e-18 | 86.7 |
| LLPS-Orm-0640 | Oryza meridionalis | 34.11 | 9e-19 | 86.7 |
| LLPS-Ori-2331 | Oryza indica | 34.11 | 3e-18 | 86.3 |
| LLPS-Orni-1199 | Oryza nivara | 34.11 | 2e-18 | 85.9 |
| LLPS-Pug-0664 | Puccinia graminis | 34.09 | 3e-19 | 88.2 |
| LLPS-Sem-0230 | Selaginella moellendorffii | 34.06 | 2e-20 | 91.7 |
| LLPS-Scp-0190 | Schizosaccharomyces pombe | 34.06 | 8e-19 | 85.9 |
| LLPS-Sac-0463 | Saccharomyces cerevisiae | 33.81 | 1e-13 | 71.6 |
| LLPS-Brd-0453 | Brachypodium distachyon | 33.6 | 1e-19 | 89.7 |
| LLPS-Amt-0530 | Amborella trichopoda | 33.59 | 2e-18 | 85.9 |
| LLPS-Asni-0520 | Aspergillus niger | 33.33 | 2e-23 | 99.4 |
| LLPS-Asg-0572 | Ashbya gossypii | 33.33 | 7e-14 | 72.4 |
| LLPS-Asc-0859 | Aspergillus clavatus | 33.13 | 5e-22 | 95.1 |
| LLPS-Nec-0501 | Neurospora crassa | 32.93 | 1e-25 | 105 |
| LLPS-Lep-0933 | Leersia perrieri | 32.81 | 7e-19 | 88.6 |
| LLPS-Yal-0278 | Yarrowia lipolytica | 32.48 | 6e-12 | 67.0 |
| LLPS-Cogr-0069 | Colletotrichum graminicola | 32.47 | 1e-18 | 85.5 |
| LLPS-Cus-0613 | Cucumis sativus | 32.03 | 4e-21 | 93.6 |
| LLPS-Cii-0121 | Ciona intestinalis | 31.94 | 5e-22 | 94.7 |
| LLPS-Beb-0279 | Beauveria bassiana | 31.68 | 1e-19 | 89.0 |
| LLPS-Ved-0452 | Verticillium dahliae | 30.77 | 2e-23 | 99.4 |
| LLPS-Tru-1479 | Triticum urartu | 30.77 | 2e-17 | 83.2 |
| LLPS-Miv-0665 | Microbotryum violaceum | 30.69 | 7e-16 | 78.6 |
| LLPS-Tum-0417 | Tuber melanosporum | 30.07 | 2e-13 | 70.1 |
| LLPS-Usm-0286 | Ustilago maydis | 29.79 | 2e-12 | 69.3 |
| LLPS-Scc-0538 | Schizosaccharomyces cryophilus | 29.53 | 4e-19 | 87.0 |
| LLPS-Cae-1447 | Caenorhabditis elegans | 29.31 | 9e-16 | 77.0 |
| LLPS-Aso-0040 | Aspergillus oryzae | 29.17 | 1e-17 | 83.2 |
| LLPS-Asf-0254 | Aspergillus flavus | 29.17 | 1e-17 | 83.2 |
| LLPS-Ast-1034 | Aspergillus terreus | 29.09 | 1e-20 | 91.7 |
| LLPS-Spr-1208 | Sporisorium reilianum | 28.65 | 5e-10 | 62.0 |
| LLPS-Chr-0287 | Chlamydomonas reinhardtii | 28.3 | 3e-08 | 57.0 |
| LLPS-Asn-1428 | Aspergillus nidulans | 25.64 | 1e-14 | 74.3 |
| LLPS-Crn-0632 | Cryptococcus neoformans | 24.86 | 4e-08 | 56.6 |