LLPS-Mua-1392
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | DNA polymerase |
| Ensembl Gene: | GSMUA_Achr3G10360_001 |
| Ensembl Protein: | GSMUA_Achr3P10360_001 |
| Organism: | Musa acuminata |
| Taxa ID: | 214687 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | GSMUA_Achr3T10360_001 | GSMUA_Achr3P10360_001 |
| UniProt | M0SDF3, M0SDF3_MUSAM |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAPRRGSQNR QRSPTPDPDG MFQGMVVFLV PKGVQPRRLQ KAMLGEHGNL DETTPKDLRK 60 61 PGWLVDFSVW KQKLTQMGAV VDDNLSKRVT HIFAMNSSTL LQQVNLERLH RHEGSLLHYQ 120 121 WLENCLRLGE KIAEDPYVLK FQGVNRSDKH SGKISPEPSE ARYSDDELSS HKRIKVSSKV 180 181 TRRLSSFDNA DVSQSQSPYN PPDLNRNITE IFGKLINIYR ALGDERRSFS YYKAIPIIEK 240 241 LPFRIESVDQ VKNLPTIGKS LQDHIHEIVT TGKLSKLEHF ENDDKVRTVN LFGEIWGVGP 300 301 ATALKLYEKG HRNLDDLKHD DSLTAAQKIG LKYFDDIKTR IPRHEVKDME MLLQNAGQEV 360 361 LPGVIVVCGG SYRRGKASCG DLDIVITHPD GESHKGFLPG YVQYLKDINF LREDLVFSTH 420 421 STEGTDSGVD TYFGLCTYPG RELRHRIDLK VYPKDRYAFG LIAWTGNDVL NRRLRLLAES 480 481 KGYRLDDTGL YLATQGSPGK RGTKSSTRVS CYTEKEVFDV LGFPWPEPHE RNM 533 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGCCCA GAAGGGGCTC CCAGAACCGG CAGCGGTCTC CTACCCCGGA CCCCGATGGC 60 61 ATGTTCCAGG GCATGGTCGT CTTCTTGGTC CCCAAGGGCG TCCAACCCCG AAGGCTTCAA 120 121 AAGGCAATGC TTGGAGAACA TGGTAATTTG GATGAAACAA CACCAAAAGA CCTAAGAAAA 180 181 CCTGGCTGGT TGGTTGACTT TAGTGTATGG AAGCAGAAGC TAACCCAAAT GGGAGCTGTG 240 241 GTTGATGATA ACCTCTCAAA GAGAGTTACT CATATTTTTG CAATGAACTC TAGTACGCTT 300 301 CTACAGCAAG TGAACCTGGA ACGCTTGCAT CGACATGAAG GAAGTTTACT TCATTATCAA 360 361 TGGTTAGAGA ACTGTCTAAG ATTAGGAGAA AAAATAGCTG AAGATCCATA TGTGCTGAAG 420 421 TTTCAAGGTG TTAATAGATC AGATAAGCAC TCTGGCAAGA TATCTCCTGA ACCATCTGAA 480 481 GCTAGATATT CTGATGATGA GCTGTCAAGC CACAAAAGGA TCAAAGTTTC CTCTAAGGTT 540 541 ACTAGGCGAC TTTCATCTTT TGATAATGCT GATGTGTCTC AGTCACAATC TCCATACAAC 600 601 CCACCAGATC TGAACAGGAA CATTACTGAA ATATTTGGAA AGCTGATCAA CATTTACAGA 660 661 GCATTAGGAG ATGAAAGGAG GTCATTCAGC TACTACAAGG CCATTCCTAT TATTGAGAAG 720 721 TTGCCTTTTA GAATTGAAAG TGTTGATCAG GTCAAAAATC TTCCTACAAT TGGGAAGTCA 780 781 TTGCAGGACC ATATTCATGA AATAGTGACT ACTGGAAAGT TATCTAAATT GGAGCACTTT 840 841 GAGAATGATG ACAAGGTTCG GACAGTAAAC CTTTTTGGTG AAATTTGGGG TGTTGGTCCT 900 901 GCCACTGCTC TTAAATTATA TGAAAAAGGT CACCGTAACC TTGATGATTT AAAACATGAT 960 961 GACTCATTGA CAGCTGCTCA GAAGATAGGT CTGAAGTACT TCGATGATAT AAAGACAAGA 1020 1021 ATTCCACGAC ATGAGGTTAA AGATATGGAG ATGCTTTTAC AAAATGCTGG TCAGGAGGTT 1080 1081 TTGCCTGGGG TAATCGTTGT ATGTGGAGGA TCATATAGAC GTGGAAAAGC TTCTTGTGGG 1140 1141 GACCTGGACA TTGTAATTAC TCATCCTGAT GGGGAAAGTC ATAAAGGATT CTTACCCGGG 1200 1201 TATGTTCAAT ATTTGAAGGA CATTAACTTT TTAAGAGAAG ACTTGGTATT TAGCACTCAT 1260 1261 AGCACTGAGG GTACTGATTC AGGGGTAGAC ACGTATTTTG GTCTTTGCAC ATATCCTGGT 1320 1321 AGAGAATTGC GACATCGGAT TGATTTGAAG GTGTATCCAA AGGATCGATA TGCTTTTGGA 1380 1381 CTAATAGCAT GGACTGGAAA TGATGTACTA AATAGGCGGT TGAGGTTGTT AGCAGAATCC 1440 1441 AAGGGATACA GGCTCGACGA CACGGGACTG TACTTGGCCA CCCAGGGTTC TCCTGGAAAG 1500 1501 AGAGGGACCA AATCCAGCAC CAGAGTAAGC TGTTACACGG AGAAGGAGGT GTTTGATGTA 1560 1561 CTTGGGTTCC CTTGGCCGGA ACCTCATGAG AGGAATATGT GA 1602 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Biological Process | DNA repair |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Prp-0496 | Prunus persica | 64.93 | 0.0 | 695 |
| LLPS-Pot-1817 | Populus trichocarpa | 62.59 | 0.0 | 683 |
| LLPS-Sem-1033 | Selaginella moellendorffii | 61.06 | 3e-145 | 429 |
| LLPS-Nia-0389 | Nicotiana attenuata | 60.63 | 0.0 | 674 |
| LLPS-Met-1779 | Medicago truncatula | 60.18 | 0.0 | 679 |
| LLPS-Gor-2190 | Gossypium raimondii | 59.79 | 0.0 | 659 |
| LLPS-Dac-0347 | Daucus carota | 55.57 | 0.0 | 633 |
| LLPS-Ora-3404 | Ornithorhynchus anatinus | 39.81 | 1e-42 | 164 |
| LLPS-Anc-3652 | Anolis carolinensis | 38.79 | 1e-66 | 232 |
| LLPS-Orn-3048 | Oreochromis niloticus | 38.71 | 5e-67 | 233 |
| LLPS-Poa-4178 | Pongo abelii | 38.44 | 3e-64 | 225 |
| LLPS-Mea-2630 | Mesocricetus auratus | 38.37 | 1e-65 | 229 |
| LLPS-Eqc-1271 | Equus caballus | 38.3 | 8e-67 | 232 |
| LLPS-Sah-2291 | Sarcophilus harrisii | 38.3 | 3e-66 | 231 |
| LLPS-Caj-4435 | Callithrix jacchus | 38.3 | 1e-66 | 232 |
| LLPS-Bot-1113 | Bos taurus | 38.3 | 3e-65 | 228 |
| LLPS-Ict-3555 | Ictidomys tridecemlineatus | 38.22 | 3e-66 | 231 |
| LLPS-Ova-3833 | Ovis aries | 38.12 | 3e-65 | 228 |
| LLPS-Urm-3860 | Ursus maritimus | 38.1 | 6e-64 | 225 |
| LLPS-Aim-2533 | Ailuropoda melanoleuca | 38.1 | 6e-64 | 224 |
| LLPS-Orc-2783 | Oryctolagus cuniculus | 38.07 | 5e-67 | 233 |
| LLPS-Myl-2241 | Myotis lucifugus | 37.99 | 2e-65 | 229 |
| LLPS-Loa-1193 | Loxodonta africana | 37.84 | 2e-64 | 226 |
| LLPS-Xim-3453 | Xiphophorus maculatus | 37.79 | 3e-64 | 226 |
| LLPS-Mum-3850 | Mus musculus | 37.76 | 1e-64 | 226 |
| LLPS-Asm-1436 | Astyanax mexicanus | 37.76 | 1e-62 | 221 |
| LLPS-Nol-1796 | Nomascus leucogenys | 37.69 | 1e-64 | 226 |
| LLPS-Gog-4164 | Gorilla gorilla | 37.69 | 3e-64 | 225 |
| LLPS-Orl-2284 | Oryzias latipes | 37.61 | 2e-66 | 231 |
| LLPS-Pes-3111 | Pelodiscus sinensis | 37.58 | 2e-64 | 226 |
| LLPS-Mam-1595 | Macaca mulatta | 37.58 | 5e-59 | 204 |
| LLPS-Tar-1603 | Takifugu rubripes | 37.54 | 1e-63 | 224 |
| LLPS-Caf-4579 | Canis familiaris | 37.5 | 3e-64 | 225 |
| LLPS-Hos-4327 | Homo sapiens | 37.39 | 1e-63 | 224 |
| LLPS-Pat-4196 | Pan troglodytes | 37.39 | 6e-64 | 224 |
| LLPS-Man-3273 | Macaca nemestrina | 37.39 | 7e-64 | 224 |
| LLPS-Rhb-4213 | Rhinopithecus bieti | 37.39 | 1e-63 | 224 |
| LLPS-Maf-1476 | Macaca fascicularis | 37.39 | 6e-64 | 224 |
| LLPS-Aon-1121 | Aotus nancymaae | 37.39 | 2e-64 | 226 |
| LLPS-Cea-4127 | Cercocebus atys | 37.39 | 5e-64 | 225 |
| LLPS-Mal-1276 | Mandrillus leucophaeus | 37.39 | 7e-64 | 224 |
| LLPS-Paa-3073 | Papio anubis | 37.39 | 6e-64 | 224 |
| LLPS-Dio-2444 | Dipodomys ordii | 37.32 | 4e-65 | 228 |
| LLPS-Ten-2239 | Tetraodon nigroviridis | 37.28 | 4e-64 | 225 |
| LLPS-Leo-2334 | Lepisosteus oculatus | 37.16 | 2e-59 | 213 |
| LLPS-Pap-0708 | Pan paniscus | 37.08 | 2e-63 | 223 |
| LLPS-Cap-4393 | Cavia porcellus | 37.08 | 4e-63 | 223 |
| LLPS-Icp-4089 | Ictalurus punctatus | 37.08 | 7e-64 | 224 |
| LLPS-Fec-2526 | Felis catus | 36.95 | 1e-64 | 226 |
| LLPS-Mup-2538 | Mustela putorius furo | 36.95 | 9e-64 | 224 |
| LLPS-Xet-3796 | Xenopus tropicalis | 36.92 | 1e-65 | 229 |
| LLPS-Anp-2999 | Anas platyrhynchos | 36.78 | 9e-63 | 221 |
| LLPS-Lac-1550 | Latimeria chalumnae | 36.72 | 6e-62 | 219 |
| LLPS-Fud-3295 | Fukomys damarensis | 36.64 | 6e-63 | 222 |
| LLPS-Yal-0989 | Yarrowia lipolytica | 36.36 | 4e-52 | 194 |
| LLPS-Sus-2984 | Sus scrofa | 36.36 | 3e-62 | 220 |
| LLPS-Ran-4395 | Rattus norvegicus | 36.25 | 3e-64 | 226 |
| LLPS-Ere-1001 | Erinaceus europaeus | 36.07 | 3e-63 | 218 |
| LLPS-Cogr-1408 | Colletotrichum graminicola | 35.4 | 4e-59 | 214 |
| LLPS-Trv-1059 | Trichoderma virens | 34.93 | 6e-56 | 204 |
| LLPS-Nef-0861 | Neosartorya fischeri | 34.67 | 3e-41 | 161 |
| LLPS-Otg-1462 | Otolemur garnettii | 34.57 | 4e-64 | 225 |
| LLPS-Lem-1403 | Leptosphaeria maculans | 34.34 | 5e-54 | 200 |
| LLPS-Asni-1388 | Aspergillus niger | 34.31 | 3e-53 | 197 |
| LLPS-Coo-0120 | Colletotrichum orbiculare | 34.22 | 1e-53 | 199 |
| LLPS-Chs-1031 | Chlorocebus sabaeus | 34.09 | 1e-63 | 224 |
| LLPS-Pyt-1107 | Pyrenophora teres | 34.02 | 1e-49 | 187 |
| LLPS-Zyt-1019 | Zymoseptoria tritici | 33.94 | 7e-53 | 194 |
| LLPS-Fuo-1443 | Fusarium oxysporum | 33.92 | 1e-57 | 210 |
| LLPS-Cii-0841 | Ciona intestinalis | 33.44 | 7e-49 | 177 |
| LLPS-Fus-1353 | Fusarium solani | 33.33 | 6e-56 | 206 |
| LLPS-Fia-2928 | Ficedula albicollis | 33.33 | 2e-67 | 234 |
| LLPS-Phn-0154 | Phaeosphaeria nodorum | 33.33 | 1e-47 | 181 |
| LLPS-Dar-2919 | Danio rerio | 33.05 | 9e-52 | 186 |
| LLPS-Asfu-0375 | Aspergillus fumigatus | 33.04 | 2e-51 | 191 |
| LLPS-Scm-0443 | Scophthalmus maximus | 32.86 | 2e-50 | 182 |
| LLPS-Tum-1576 | Tuber melanosporum | 32.83 | 2e-43 | 169 |
| LLPS-Asn-1181 | Aspergillus nidulans | 32.55 | 2e-47 | 179 |
| LLPS-Cog-0371 | Colletotrichum gloeosporioides | 32.49 | 9e-56 | 205 |
| LLPS-Crn-0471 | Cryptococcus neoformans | 32.34 | 6e-38 | 154 |
| LLPS-Pof-2548 | Poecilia formosa | 32.3 | 3e-49 | 179 |
| LLPS-Tag-3451 | Taeniopygia guttata | 32.29 | 2e-50 | 182 |
| LLPS-Gaa-3113 | Gasterosteus aculeatus | 32.2 | 3e-51 | 184 |
| LLPS-Beb-1473 | Beauveria bassiana | 32.11 | 2e-45 | 175 |
| LLPS-Nec-0115 | Neurospora crassa | 32.11 | 1e-50 | 190 |
| LLPS-Meg-1755 | Meleagris gallopavo | 32.06 | 4e-43 | 160 |
| LLPS-Scf-3361 | Scleropages formosus | 31.99 | 2e-39 | 151 |
| LLPS-Ved-1454 | Verticillium dahliae | 31.95 | 6e-55 | 202 |
| LLPS-Aso-0365 | Aspergillus oryzae | 31.94 | 1e-49 | 186 |
| LLPS-Asf-0738 | Aspergillus flavus | 31.94 | 2e-49 | 185 |
| LLPS-Pytr-0062 | Pyrenophora triticirepentis | 31.84 | 2e-49 | 186 |
| LLPS-Fuv-1312 | Fusarium verticillioides | 31.83 | 2e-60 | 211 |
| LLPS-Dos-1523 | Dothistroma septosporum | 31.72 | 1e-37 | 152 |
| LLPS-Mod-3239 | Monodelphis domestica | 31.59 | 3e-49 | 179 |
| LLPS-Trr-0509 | Trichoderma reesei | 31.55 | 7e-49 | 184 |
| LLPS-Mao-1344 | Magnaporthe oryzae | 31.43 | 5e-48 | 183 |
| LLPS-Gag-1131 | Gaeumannomyces graminis | 31.36 | 4e-45 | 174 |
| LLPS-Cas-1074 | Carlito syrichta | 30.88 | 2e-45 | 168 |
| LLPS-Asc-1615 | Aspergillus clavatus | 30.69 | 3e-50 | 188 |
| LLPS-Abg-1778 | Absidia glauca | 30.48 | 8e-46 | 173 |
| LLPS-Ast-1316 | Aspergillus terreus | 30.15 | 6e-49 | 184 |
| LLPS-Kop-0147 | Komagataella pastoris | 29.91 | 6e-33 | 135 |
| LLPS-Gaga-0030 | Gallus gallus | 29.64 | 3e-66 | 235 |
| LLPS-Miv-1469 | Microbotryum violaceum | 28.07 | 7e-21 | 100 |
| LLPS-Spr-1429 | Sporisorium reilianum | 27.92 | 1e-17 | 90.5 |
| LLPS-Map-1267 | Magnaporthe poae | 27.37 | 2e-32 | 136 |
| LLPS-Usm-1274 | Ustilago maydis | 26.74 | 1e-19 | 96.7 |
| LLPS-Sac-0332 | Saccharomyces cerevisiae | 26.24 | 1e-07 | 58.5 |
| LLPS-Cis-1804 | Ciona savignyi | 26.02 | 4e-27 | 118 |
| LLPS-Scc-1285 | Schizosaccharomyces cryophilus | 25.75 | 4e-25 | 112 |
| LLPS-Scp-1632 | Schizosaccharomyces pombe | 25.56 | 3e-21 | 100 |
| LLPS-Chc-0704 | Chondrus crispus | 22.72 | 3e-18 | 92.0 |
| LLPS-Asg-1415 | Ashbya gossypii | 22.28 | 1e-21 | 102 |