LLPS-Mod-a1133
ATP2A1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Calcium-transporting ATPase |
| Gene Name: | ATP2A1 |
| Ensembl Gene: | ENSMODG00000015558.3 |
| Ensembl Protein: | ENSMODP00000019420.3 |
| Organism: | Monodelphis domestica |
| Taxa ID: | 13616 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMODT00000019768.3 | ENSMODP00000019420.3 |
| UniProt | F7AJG0, F7AJG0_MONDO | |
| Entrez | 100014945 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGKVYRADRK SVQRIKARDI VPGDIVEVAV GDKVPADIRI LSIKSTTLRV DQSILTGESV 60 61 SVIKHTEPVP DPRAVNQDKK NMLFSGTNIA AGKAVGIVAT TGVSTEIGKI RDQMAATEQE 120 121 KTPLQQKLDE FGEQLSKVIS LICVAVWLIN IGHFNDPVHG GSWFRGAIYY FKIAVALAVA 180 181 AIPEGLPAVI TTCLALGTRR MAKKNAIVRS LPSVETLGCT SVICSDKTGT LTTNQMSVCK 240 241 MFVIDKVDGD LCSLNEFAIT GSTYAPEGEV LKNDKPVRSG QYDGLVELAT ICALCNDSSL 300 301 DFNESKGVYE KVGEATETAL TTLVEKMNVF NTDVRSLSKV ERANACNSVI RQLMKKEFTL 360 361 EFSRDRKSMS VYCSPAKSSR AAVGNKMFVK GAPEGVIDRC NYVRVGTTRV PLTTPVKDKI 420 421 MTVIKEWGTG RDTLRCLALA TRDTPPRREE MSLDDSAKFM EYETDLTFVG VVGMLDPPRK 480 481 EVMGSIQLCR DAGIRVIMIT GDNKGTAIAI CRRIGIFGEN EEVTGRAYTG REFDDLPLGE 540 541 QRDACRRACC FARVEPSHKS KIVEFLQSFD EITAMTGDGV NDAPALKKAE IGIAMGSGTA 600 601 VAKTASEMVL ADDNFSTIVS AVEEGRAIYN NMKQFIRYLI SSNVGEVVCI FLTAALGLPE 660 661 ALIPVQLLWV NLVTDGLPAT ALGFNPPDLD IMDRPPRSPK EPLISGWLFF RYMAIGGYVG 720 721 AATVGAAAWW FLYAEDGPHV SYNQLTHFMQ CTEENPDFEG LDCEVFEAPE PMTMALSVLV 780 781 TIEMCNALNS LSENQSLLRM PPWVNIWLLG SICLSMSLHF LILYVDPLPM IFKLRALDVT 840 841 QWMMVLKISL PVIGLDELLK FIARNYLEDP EEEEGEGYEE PDGEGASVAY ENSQDQISQD 900 901 GWGYENEE 908 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGGCAAAG TGTACAGGGC TGACCGAAAG TCCGTACAGA GGATCAAGGC CCGGGACATC 60 61 GTCCCTGGGG ACATCGTGGA GGTGGCTGTG GGTGACAAAG TCCCTGCAGA TATCCGAATC 120 121 CTCTCCATCA AATCCACTAC ACTTCGGGTT GACCAGTCCA TCCTCACAGG TGAGTCTGTG 180 181 TCTGTCATCA AGCATACAGA ACCTGTCCCT GACCCACGAG CTGTTAACCA GGACAAGAAG 240 241 AATATGCTTT TCTCGGGCAC CAACATTGCA GCAGGAAAGG CAGTAGGCAT CGTGGCGACC 300 301 ACTGGAGTGA GCACAGAGAT TGGGAAAATT CGGGACCAGA TGGCAGCCAC AGAACAAGAA 360 361 AAGACACCCC TGCAGCAGAA GCTGGATGAG TTTGGGGAGC AGCTGTCCAA AGTTATCTCC 420 421 TTGATCTGCG TGGCTGTGTG GCTCATCAAC ATCGGGCACT TCAACGACCC CGTCCATGGG 480 481 GGCTCCTGGT TCCGTGGTGC CATCTACTAC TTTAAGATAG CGGTGGCCTT GGCTGTGGCT 540 541 GCCATTCCCG AAGGGCTGCC TGCCGTCATC ACCACCTGTC TGGCCCTGGG CACCCGTCGG 600 601 ATGGCAAAGA AGAATGCCAT CGTGAGGAGC CTGCCCTCTG TGGAAACTCT GGGCTGCACC 660 661 TCAGTCATCT GCTCGGACAA GACCGGCACC CTCACCACCA ACCAGATGTC GGTCTGCAAG 720 721 ATGTTTGTCA TTGATAAGGT GGATGGGGAT CTCTGCTCTC TGAATGAATT TGCCATCACC 780 781 GGTTCCACTT ATGCCCCTGA GGGTGAAGTC TTGAAGAATG ATAAGCCAGT CAGATCAGGT 840 841 CAGTACGATG GGCTGGTAGA GCTGGCCACC ATCTGTGCCC TCTGCAATGA CTCTTCCTTG 900 901 GACTTCAATG AGTCCAAAGG TGTTTATGAG AAGGTCGGGG AGGCCACCGA GACAGCACTT 960 961 ACTACCCTGG TGGAAAAGAT GAATGTGTTC AACACAGATG TGAGAAGTCT CTCCAAGGTG 1020 1021 GAGAGGGCCA ATGCCTGCAA CTCTGTGATC CGCCAGCTGA TGAAGAAAGA ATTCACCTTG 1080 1081 GAGTTTTCCC GTGACAGGAA GTCTATGTCT GTTTATTGCT CCCCAGCTAA ATCTTCCCGG 1140 1141 GCTGCCGTGG GAAACAAGAT GTTTGTCAAG GGAGCTCCTG AGGGAGTCAT TGACCGTTGT 1200 1201 AATTATGTGC GGGTTGGCAC AACCAGGGTG CCACTAACAA CACCAGTGAA GGACAAAATC 1260 1261 ATGACTGTAA TCAAGGAGTG GGGCACAGGC CGAGATACTC TCCGATGCTT GGCCTTGGCC 1320 1321 ACCCGGGACA CTCCACCCAG GCGAGAGGAG ATGTCACTAG ATGATTCTGC CAAATTTATG 1380 1381 GAATATGAGA CGGATTTGAC GTTTGTTGGG GTAGTGGGAA TGTTGGATCC GCCTCGCAAG 1440 1441 GAGGTCATGG GCTCTATCCA GCTGTGCCGG GACGCTGGGA TCCGAGTCAT CATGATCACA 1500 1501 GGTGACAACA AGGGCACAGC CATCGCCATC TGCAGGCGCA TCGGCATCTT TGGGGAGAAT 1560 1561 GAGGAGGTGA CGGGCCGAGC CTACACGGGC CGAGAATTTG ATGATTTGCC CCTTGGAGAG 1620 1621 CAGCGAGATG CCTGTCGCCG GGCTTGTTGC TTTGCCCGGG TGGAACCTTC CCACAAGTCG 1680 1681 AAGATCGTCG AGTTCCTGCA GTCTTTCGAT GAGATCACTG CTATGACAGG GGATGGGGTG 1740 1741 AATGATGCCC CAGCTCTGAA GAAGGCTGAG ATTGGTATTG CCATGGGCTC TGGCACCGCT 1800 1801 GTGGCTAAAA CTGCCTCTGA GATGGTGCTT GCAGATGATA ACTTCTCCAC CATTGTGTCT 1860 1861 GCTGTGGAGG AGGGCCGAGC CATCTACAAC AACATGAAGC AGTTTATCCG ATACCTTATT 1920 1921 TCCTCCAACG TGGGGGAGGT CGTCTGTATC TTCCTGACAG CAGCCTTGGG GTTGCCTGAG 1980 1981 GCCTTGATCC CTGTACAACT GTTGTGGGTA AATCTGGTGA CTGATGGACT TCCAGCCACA 2040 2041 GCCCTGGGCT TCAACCCTCC AGATCTGGAC ATCATGGACC GTCCCCCAAG AAGTCCTAAG 2100 2101 GAGCCCCTTA TTAGTGGCTG GCTCTTCTTC CGCTACATGG CAATTGGGGG TTATGTGGGT 2160 2161 GCAGCCACAG TAGGTGCAGC AGCTTGGTGG TTCCTGTATG CAGAAGATGG GCCTCATGTC 2220 2221 AGCTATAACC AGCTGACTCA TTTCATGCAG TGCACAGAGG AAAATCCTGA CTTTGAGGGT 2280 2281 CTGGACTGTG AGGTCTTTGA AGCTCCTGAG CCCATGACCA TGGCCTTGTC TGTGCTGGTC 2340 2341 ACCATTGAGA TGTGCAATGC TCTCAACAGC CTCTCAGAGA ACCAGTCCCT ACTTCGGATG 2400 2401 CCCCCCTGGG TGAACATCTG GCTCCTTGGG TCCATTTGCC TTTCCATGTC TCTCCATTTC 2460 2461 CTTATCCTTT ACGTCGATCC CCTGCCGATG ATTTTCAAAC TTCGGGCACT GGATGTAACC 2520 2521 CAGTGGATGA TGGTCCTGAA GATCTCATTG CCTGTCATTG GTCTGGATGA ACTCCTCAAG 2580 2581 TTTATTGCCC GGAATTACCT GGAGGATCCA GAAGAGGAAG AAGGGGAAGG TTATGAGGAG 2640 2641 CCAGATGGTG AAGGGGCTTC TGTGGCCTAT GAAAATAGCC AGGACCAGAT CTCCCAAGAT 2700 2701 GGCTGGGGCT ATGAGAATGA GGAG 2724 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Mitochondrion | |
Cellular Component | Sarcoplasmic reticulum membrane | |
Molecular Function | ATP binding | |
Molecular Function | Calcium ion binding | |
Molecular Function | Calcium-transporting ATPase activity | |
Molecular Function | Protein homodimerization activity | |
Molecular Function | Proton-exporting ATPase activity, phosphorylative mechanism | |
Biological Process | Apoptotic mitochondrial changes | |
Biological Process | Calcium ion import | |
Biological Process | Calcium ion transmembrane transport | |
Biological Process | Cellular calcium ion homeostasis | |
Biological Process | Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | |
Biological Process | Maintenance of mitochondrion location | |
Biological Process | Negative regulation of endoplasmic reticulum calcium ion concentration | |
Biological Process | Positive regulation of endoplasmic reticulum calcium ion concentration | |
Biological Process | Positive regulation of fast-twitch skeletal muscle fiber contraction | |
Biological Process | Positive regulation of mitochondrial calcium ion concentration | |
Biological Process | Relaxation of skeletal muscle |