LLPS-Meg-a877
VPS16
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Vacuolar protein sorting-associated protein 16 homolog |
| Gene Name: | VPS16 |
| Ensembl Gene: | ENSMGAG00000013704.2 |
| Ensembl Protein: | ENSMGAP00000014482.2 |
| Organism: | Meleagris gallopavo |
| Taxa ID: | 9103 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMGAT00000015418.2 | ENSMGAP00000014482.2 |
| UniProt | G1NLR8, G1NLR8_MELGA |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDCYTANWNP LGEEAFYRHC LELGKIRRNS RRGELLCLRG AAVRGTRTAN AELQPLASFA 60 61 SPGGGSLAVS CLQWKSGQLV QLGWTASEDL LCIQEDGTVL IYNLFCEFKR HFSMGNEVLQ 120 121 NHVLEAKVFH TEYGTGVAIL TGAHRFSLTT NIDDLKLRRM PEVPGLQKPP SCWAVLTQDR 180 181 VTIVLLAVGQ DLYLLDNTSC SVVTPPGMSP SAGAYLQMAV SFNYRCLALF TDTGYIWMGL 240 241 ATLKDKLCEF NSAIRSAPKQ MVWCTRPRSR QRAVVLAWDR QLMVAGELSD GSASDFPSAE 300 301 QPTSLPALRA ELGHKSPAAG RAVPEPSADS PGADLLLAEL GCSRQLLSSH EPLAGGTMGR 360 361 VGQQSLTQTS RPHSAQLPAS PWAAEQGQPP ARTARCCAQP VPVMLSPCHG AEPALPSSAS 420 421 QYKRLTVEVL LDRLVLRRLY PLAIRICEYL RLPEIQGVSR ILAHWACYKV QQKDKSDEEV 480 481 AYAINQKLGD TPGISYSEIA ARAYDCGRTE LAIKLLEYEP RSGEQVPLLL KMKRSKLALS 540 541 KAIESGDTDL VYTVVLHLKN ELNRGTFFMT LQNQPVALSL YRQFCKHQER ETLKDLYNQD 600 601 DNHQELGNFH VHSSYSEKRI EGRVGALQNA VDEYYKAKNE FAAKATEDQI KLLRLQRHLQ 660 661 EDFDKPYLDL SLHNTVSTLI QDGHHKKAEQ LYREFKIPDK RYWWLKISAL ATRGDWEEME 720 721 KFSKSKKSPI GYLPFVEIAV KHHNRYEAKK YAPRVTPEQR VKAFILVGDL EQAADAAIEH 780 781 KNETEMNLVL SKCSATTDGA VVEKLNRARA QLLKK 815 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGACTGCT ACACGGCCAA CTGGAACCCG CTGGGCGAAG AGGCCTTCTA CCGCCATTGT 60 61 CTAGAGCTGG GGAAGATACG GAGAAACAGC AGGAGGGGTG AGCTGTTGTG CCTGCGGGGG 120 121 GCTGCAGTCA GGGGCACCAG AACTGCAAAT GCTGAACTGC AGCCACTGGC ATCGTTTGCA 180 181 TCCCCTGGAG GGGGCAGCTT GGCAGTTTCC TGCTTGCAGT GGAAGAGTGG CCAGCTGGTG 240 241 CAGCTGGGCT GGACAGCCAG TGAGGACCTG CTGTGCATCC AGGAGGATGG CACTGTTCTC 300 301 ATCTACAACC TCTTCTGCGA GTTCAAGCGT CACTTCAGCA TGGGCAACGA GGTGCTGCAG 360 361 AACCACGTGC TGGAGGCGAA GGTCTTCCAC ACAGAGTACG GCACCGGTGT GGCCATCCTC 420 421 ACTGGAGCAC ACCGCTTCTC GCTGACCACC AACATCGATG ACCTGAAGCT GCGCAGGATG 480 481 CCCGAGGTGC CAGGTCTGCA GAAGCCGCCC TCTTGCTGGG CTGTGCTGAC CCAAGACAGA 540 541 GTGACCATCG TCCTGCTGGC GGTCGGCCAG GACCTGTACC TGCTGGACAA CACCTCCTGC 600 601 TCCGTGGTGA CGCCCCCTGG CATGAGCCCC TCCGCTGGTG CCTACCTGCA GATGGCCGTG 660 661 TCCTTCAACT ACCGCTGCCT GGCACTCTTC ACTGACACTG GCTACATCTG GATGGGGTTG 720 721 GCCACGCTGA AGGACAAGCT CTGCGAGTTC AACAGCGCCA TCCGGTCTGC ACCCAAGCAG 780 781 ATGGTTTGGT GCACACGTCC CCGCAGCCGG CAGCGCGCCG TGGTGCTGGC CTGGGACCGG 840 841 CAGCTCATGG TGGCTGGGGA ACTTTCCGAC GGGAGTGCAT CCGACTTTCC CAGTGCAGAG 900 901 CAACCCACCT CCCTCCCAGC TCTGAGAGCA GAGCTTGGCC ACAAGAGCCC TGCGGCCGGT 960 961 AGGGCTGTGC CAGAGCCCTC AGCCGATTCC CCGGGGGCTG ACCTGCTCCT GGCAGAGCTG 1020 1021 GGCTGCAGCC GGCAGCTGCT TTCTTCCCAC GAGCCCTTAG CGGGAGGCAC GATGGGGAGG 1080 1081 GTTGGGCAGC AGAGCCTCAC TCAGACCAGC CGGCCCCACA GTGCTCAGCT ACCGGCTTCG 1140 1141 CCCTGGGCCG CAGAGCAGGG TCAGCCTCCT GCACGCACTG CACGGTGCTG CGCCCAACCT 1200 1201 GTGCCTGTGA TGCTGAGCCC GTGTCATGGT GCTGAGCCTG CCCTGCCCTC AAGTGCCAGC 1260 1261 CAATACAAAC GACTCACCGT TGAGGTCTTG CTGGACAGGC TGGTCCTGCG GCGGCTCTAC 1320 1321 CCCCTGGCCA TCAGGATCTG TGAGTACCTG CGCCTCCCGG AGATCCAGGG CGTCAGCCGC 1380 1381 ATCCTGGCCC ACTGGGCCTG CTACAAGGTG CAGCAGAAGG ACAAGTCTGA CGAGGAGGTG 1440 1441 GCTTATGCCA TCAACCAGAA GCTGGGTGAC ACGCCAGGCA TCTCCTACTC TGAGATCGCT 1500 1501 GCCCGAGCGT ACGACTGCGG CAGGACAGAG CTGGCCATCA AGCTGCTGGA GTACGAGCCA 1560 1561 CGCTCTGGGG AGCAGGTCCC ACTGCTGCTG AAGATGAAGC GGAGCAAGCT GGCCCTGAGC 1620 1621 AAAGCCATCG AGAGTGGGGA CACAGACCTG GTCTACACTG TCGTGCTGCA CCTGAAGAAC 1680 1681 GAGCTGAATC GTGGCACCTT CTTCATGACG CTGCAGAACC AGCCGGTGGC TCTGAGCCTC 1740 1741 TATCGCCAGT TTTGCAAGCA CCAGGAGCGA GAGACGCTGA AGGACTTGTA CAACCAGGAT 1800 1801 GACAACCACC AGGAGCTCGG CAACTTCCAT GTCCACTCCA GCTACTCAGA GAAGCGCATT 1860 1861 GAAGGGCGGG TGGGAGCCCT GCAGAATGCT GTGGATGAGT ACTACAAGGC CAAGAATGAG 1920 1921 TTTGCTGCCA AGGCCACAGA GGATCAGATC AAGCTCCTGC GGCTCCAGCG ACACCTCCAG 1980 1981 GAGGACTTTG ACAAGCCCTA CCTCGACCTC TCTCTGCACA ACACCGTCTC CACCCTGATC 2040 2041 CAGGACGGCC ACCACAAGAA AGCTGAGCAG CTGTACCGGG AGTTCAAGAT CCCCGACAAG 2100 2101 CGGTACTGGT GGCTGAAGAT CAGTGCCCTG GCCACCCGCG GGGACTGGGA GGAGATGGAG 2160 2161 AAGTTCTCCA AGAGCAAGAA GTCGCCCATC GGGTACCTGC CCTTCGTGGA GATTGCTGTG 2220 2221 AAGCACCACA ACCGCTACGA GGCCAAGAAG TACGCACCCC GTGTCACCCC TGAGCAGCGG 2280 2281 GTCAAGGCCT TCATCCTTGT GGGGGACCTG GAGCAGGCGG CTGACGCTGC CATCGAGCAC 2340 2341 AAGAACGAGA CTGAGATGAA CCTCGTCCTG TCCAAGTGCT CTGCCACCAC TGACGGCGCC 2400 2401 GTGGTGGAGA AGCTGAACCG GGCTCGTGCC CAGCTCCTGA AGAAGTGA 2448 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | CORVET complex | |
Cellular Component | Early endosome | |
Cellular Component | HOPS complex | |
Cellular Component | Late endosome membrane | |
Cellular Component | Lysosomal membrane | |
Cellular Component | Recycling endosome | |
Biological Process | Autophagosome maturation | |
Biological Process | Endosome to lysosome transport | |
Biological Process | Intracellular protein transport | |
Biological Process | Vacuole organization |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a1150 | Homo sapiens | 0.0 | 1011 | undefined |
| LLPS-Mum-a1130 | Mus musculus | 0.0 | 994 | undefined |