• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Mea-a643
Lin7c

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Protein lin-7 homolog
Gene Name: Lin7c
Ensembl Gene: ENSMAUG00000021220.1
Ensembl Protein: ENSMAUP00000024324.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION


Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAALGEPVRL  ERDICRAIEL  LEKLQRSGEV  PPQKLQALQR  VLQSEFCNAV  REVYEHVYET  60
61    VDISSSPEVR  ANATAKATVA  AFAASEGHSH  PRVVELPKTE  EGLGFNIMGG  KEQNSPIYIS  120
121   RIIPGGIADR  HGGLKRGDQL  LSVNGVSVEG  EHHEKAVELL  KAAQGKVKLV  VRYTPKVLEE  180
181   MESRFEKMRS  AKRRQQT  197

▼ KEYWORD


ID
Family
Cell junction
Cell membrane
Complete proteome
Exocytosis
Membrane
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Basolateral plasma membrane
Cellular Component
Cell-cell junction
Cellular Component
Cytoplasm
Cellular Component
MPP7-DLG1-LIN7 complex
Cellular Component
Presynapse
Molecular Function
Cytoskeletal protein binding
Molecular Function
L27 domain binding
Biological Process
Exocytosis
Biological Process
Morphogenesis of an epithelial sheet
Biological Process
Neurotransmitter secretion
Biological Process
Protein transport

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-a691Homo sapiens1e-140400undefined
LLPS-Mum-a685Mus musculus1e-140400undefined