• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-2499
Prkra

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1
Gene Name: Prkra
Ensembl Gene: ENSMAUG00000019631.1
Ensembl Protein: ENSMAUP00000022086.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSHSRHRAEA  PPLEREDSGT  FSLGKMITAK  PGKTPIQVLH  EYGMKTKNIP  VYECERSDVQ  60
61    IHVPTFTFRV  TVGDITCTGE  GTSKKLAKHR  AAEAAINILK  ANASICFAVP  DPLMPDPSKQ  120
121   PKNQLNPIGS  LQELAIHHGW  RLPEYTLSQE  GGPAHKREYT  TICRLESFME  TGKGASKKQA  180
181   KRNAAEKFLA  KFSNISPENH  ISLTNVVGHS  LGCTWHSLRN  SPGEKINLLK  RSLLSLPNTD  240
241   YIQLLSEIAK  EQGFTITYLD  IEELSANGQY  QCLAELSTSP  ITVCHGSGIS  CGNAQSDAAH  300
301   NALQYLKIIA  ERK  313
Nucleotide CDS Sequence (FASTA)
1     ATGTCCCACA  GCAGGCATCG  CGCCGAGGCC  CCGCCGCTGG  AGCGCGAGGA  CAGCGGGACC  60
61    TTCAGTTTGG  GCAAGATGAT  AACAGCCAAG  CCTGGGAAAA  CACCGATTCA  GGTATTGCAC  120
121   GAATACGGCA  TGAAGACCAA  GAACATTCCA  GTTTATGAAT  GTGAAAGATC  CGATGTGCAA  180
181   ATACACGTGC  CCACTTTCAC  CTTCAGAGTA  ACCGTTGGTG  ACATAACTTG  CACAGGCGAA  240
241   GGTACAAGTA  AGAAGCTGGC  GAAGCACAGA  GCTGCAGAGG  CCGCCATAAA  CATTTTGAAA  300
301   GCCAATGCAA  GCATTTGCTT  TGCAGTTCCT  GACCCCTTAA  TGCCTGATCC  ATCCAAACAG  360
361   CCAAAGAACC  AGCTGAATCC  AATTGGCTCA  TTACAGGAAT  TGGCTATTCA  TCATGGCTGG  420
421   CGACTTCCTG  AATATACCCT  TTCCCAGGAA  GGAGGACCTG  CTCATAAGAG  AGAGTATACC  480
481   ACAATTTGCA  GGCTAGAATC  ATTCATGGAA  ACTGGAAAGG  GAGCATCCAA  AAAACAAGCC  540
541   AAGAGAAATG  CAGCTGAGAA  ATTTCTCGCC  AAATTTAGTA  ACATTTCTCC  AGAGAACCAC  600
601   ATTTCTCTAA  CAAATGTGGT  TGGACATTCT  CTAGGATGTA  CTTGGCATTC  ATTGAGGAAT  660
661   TCCCCTGGTG  AAAAGATCAA  CTTACTGAAA  AGAAGCCTCC  TCAGTCTCCC  GAACACAGAC  720
721   TATATCCAGC  TGCTTAGCGA  GATTGCCAAG  GAACAAGGTT  TTACCATAAC  CTATTTGGAT  780
781   ATAGAGGAAC  TGAGTGCCAA  TGGACAGTAT  CAGTGTCTCG  CAGAACTGTC  CACCAGTCCT  840
841   ATCACCGTGT  GTCATGGCTC  GGGCATCTCC  TGTGGCAATG  CACAGAGTGA  CGCTGCTCAC  900
901   AATGCTCTGC  AGTATTTAAA  GATAATCGCA  GAAAGAAAGT  AG  942

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Eqc-1942Equus caballus99.320.0 601
LLPS-Ran-4773Rattus norvegicus99.040.0 649
LLPS-Caj-4771Callithrix jacchus99.040.0 646
LLPS-Cas-2608Carlito syrichta99.040.0 646
LLPS-Mal-3333Mandrillus leucophaeus98.960.0 595
LLPS-Nol-2502Nomascus leucogenys98.960.0 595
LLPS-Urm-2983Ursus maritimus98.960.0 595
LLPS-Pap-4096Pan paniscus98.850.0 540
LLPS-Mup-4338Mustela putorius furo98.720.0 644
LLPS-Paa-4628Papio anubis98.720.0 645
LLPS-Aon-1936Aotus nancymaae98.720.0 645
LLPS-Cea-1304Cercocebus atys98.720.0 645
LLPS-Sus-3458Sus scrofa98.720.0 644
LLPS-Mum-3253Mus musculus98.720.0 646
LLPS-Maf-4020Macaca fascicularis98.720.0 645
LLPS-Man-3426Macaca nemestrina98.720.0 645
LLPS-Fec-3898Felis catus98.720.0 644
LLPS-Pat-4705Pan troglodytes98.720.0 645
LLPS-Hos-0570Homo sapiens98.720.0 645
LLPS-Aim-0247Ailuropoda melanoleuca98.40.0 643
LLPS-Gog-0615Gorilla gorilla98.40.0 644
LLPS-Poa-3720Pongo abelii98.40.0 638
LLPS-Rhb-2007Rhinopithecus bieti98.40.0 643
LLPS-Otg-1216Otolemur garnettii98.40.0 642
LLPS-Mam-3972Macaca mulatta98.310.0 605
LLPS-Ict-4267Ictidomys tridecemlineatus98.080.0 639
LLPS-Cap-3003Cavia porcellus98.080.0 639
LLPS-Ova-3753Ovis aries97.440.0 639
LLPS-Bot-4865Bos taurus97.440.0 639
LLPS-Loa-4503Loxodonta africana97.138e-177 496
LLPS-Myl-1492Myotis lucifugus97.120.0 631
LLPS-Orc-3219Oryctolagus cuniculus97.120.0 633
LLPS-Dio-0016Dipodomys ordii96.170.0 632
LLPS-Fud-3824Fukomys damarensis94.520.0 600
LLPS-Chs-4784Chlorocebus sabaeus93.140.0 598
LLPS-Caf-4577Canis familiaris84.070.0 553
LLPS-Sah-4114Sarcophilus harrisii81.440.0 511
LLPS-Lac-0168Latimeria chalumnae65.651e-134 392
LLPS-Anc-1232Anolis carolinensis64.637e-137 399
LLPS-Fia-1158Ficedula albicollis60.473e-1368.2
LLPS-Asm-0594Astyanax mexicanus55.761e-88 274
LLPS-Leo-1998Lepisosteus oculatus55.78e-108 323
LLPS-Icp-3733Ictalurus punctatus54.092e-101 306
LLPS-Orn-2668Oreochromis niloticus53.994e-84 262
LLPS-Gaa-0921Gasterosteus aculeatus53.715e-84 262
LLPS-Scf-0809Scleropages formosus52.463e-94 289
LLPS-Scm-3089Scophthalmus maximus52.091e-87 273
LLPS-Dar-3022Danio rerio50.872e-80 253
LLPS-Xim-1104Xiphophorus maculatus50.74e-89 275
LLPS-Pof-0162Poecilia formosa50.72e-82 258
LLPS-Anp-1356Anas platyrhynchos50.01e-0650.1
LLPS-Ten-1841Tetraodon nigroviridis49.347e-76 241
LLPS-Gaga-3018Gallus gallus48.575e-61 202
LLPS-Tar-1443Takifugu rubripes45.812e-74 238
LLPS-Xet-3813Xenopus tropicalis43.631e-78 250
LLPS-Tag-0991Taeniopygia guttata38.198e-44 156
LLPS-Mod-1709Monodelphis domestica34.31e-1682.0
LLPS-Pes-0100Pelodiscus sinensis34.296e-1682.0
LLPS-Drm-0171Drosophila melanogaster31.653e-0962.0
LLPS-Meg-1351Meleagris gallopavo30.921e-1787.4
LLPS-Orl-2182Oryzias latipes30.892e-1477.4
LLPS-Ora-0903Ornithorhynchus anatinus30.723e-1065.1