• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-2457
Pes1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pescadillo homolog
Gene Name: Pes1, PES1
Ensembl Gene: ENSMAUG00000018433.1
Ensembl Protein: ENSMAUP00000020429.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRGLKRDNKI  RNTGLGSATN  YITRNKARKK  LQLSLPDFRR  LCILKGIYPH  EPKHKKKVNK  60
61    GSTAARTFYL  IKDIKFLLHE  PIVNKFREYK  VFVRKLRKAY  GKSEWNSVER  LKDNKPSYKL  120
121   DHIVKERYPT  FIDALRDLDD  ALSMCFLFST  FPRTGKCHVQ  TIQLCRRLTV  EFMHYVIAAR  180
181   ALRKVFLSIK  GIYYQAEVLG  QPIVWIAPYA  FSHDHPTDVD  YRVMATFTEF  YTTLLGFVNF  240
241   RLYQSLNLHY  PPKLEGQAQA  ETKISEDTYA  LDSESSMEKL  AALSASLARV  VMPTIEEAEA  300
301   DEFPTDGEVT  AQEEGHRREL  EAQEKQKKLF  EGLRFFLNRE  VPREALAFII  RSFGGDVSWD  360
361   KSLCIGATYD  ITDSCITHQI  VDRPGQQTPV  IGRYYVQPQW  VFDCVNARLL  LPVAEYFPGV  420
421   QLPPHLSPFV  SEKEGDYIPP  EKLKLLALQR  GEDPGELDED  EDDEEDEDGD  NEGDGDVAGE  480
481   NEEEEDVGAD  SEMEEEAHLS  ALEQQRLEGK  KPQVVAGTVK  LEDKQRLAQE  EESEAKRLAI  540
541   MMMKKREKYL  YQKIMFGKRR  KIREANKLAE  KRKAHDDAVK  SEKRAKRTRP  V  591
Nucleotide CDS Sequence (FASTA)
1     ATGAGGGGGT  TAAAAAGGGA  CAATAAGATC  AGGAACACAG  GATTAGGCTC  TGCCACCAAT  60
61    TATATCACCC  GAAACAAAGC  CCGGAAGAAG  CTGCAGCTGA  GCCTGCCTGA  TTTCAGGCGG  120
121   CTGTGCATCC  TAAAAGGCAT  TTATCCCCAT  GAGCCCAAGC  ATAAGAAGAA  GGTGAACAAG  180
181   GGTTCCACAG  CAGCCCGCAC  ATTTTACCTT  ATCAAAGACA  TTAAATTCCT  CCTCCATGAG  240
241   CCCATCGTCA  ACAAGTTCCG  AGAGTACAAG  GTGTTTGTTC  GGAAGCTCCG  CAAAGCCTAT  300
301   GGGAAGAGTG  AGTGGAATTC  TGTGGAGCGC  CTGAAGGACA  ATAAACCCAG  CTACAAACTC  360
361   GACCACATTG  TCAAGGAGCG  GTACCCCACA  TTCATCGATG  CTCTGAGGGA  CCTCGATGAT  420
421   GCCCTGTCAA  TGTGCTTCCT  CTTCTCCACA  TTCCCACGGA  CGGGCAAGTG  CCATGTACAG  480
481   ACCATTCAGC  TGTGTCGCCG  GCTCACTGTG  GAGTTCATGC  ACTACGTCAT  TGCTGCCCGA  540
541   GCCCTGCGCA  AAGTCTTCCT  GTCCATCAAA  GGCATTTACT  ATCAGGCTGA  GGTGCTGGGG  600
601   CAGCCCATCG  TATGGATTGC  ACCCTATGCT  TTCTCCCATG  ATCATCCAAC  AGATGTGGAC  660
661   TACAGGGTCA  TGGCCACCTT  CACTGAGTTC  TACACTACTC  TTCTGGGCTT  CGTGAACTTC  720
721   CGCCTTTACC  AGTCGCTCAA  CCTTCACTAC  CCCCCCAAGC  TTGAAGGTCA  AGCCCAGGCA  780
781   GAGACAAAGA  TCAGCGAGGA  CACATATGCA  CTGGACTCTG  AGAGCTCTAT  GGAGAAACTA  840
841   GCAGCGCTCA  GCGCCAGTCT  GGCCCGAGTG  GTGATGCCTA  CTATAGAGGA  GGCTGAGGCC  900
901   GATGAGTTTC  CTACTGATGG  GGAGGTGACA  GCCCAGGAGG  AAGGTCACAG  GAGAGAGCTG  960
961   GAGGCACAGG  AAAAACAGAA  GAAACTCTTT  GAAGGCCTGA  GATTCTTCCT  GAACCGAGAG  1020
1021  GTGCCCCGTG  AAGCATTGGC  CTTCATCATC  AGGAGTTTTG  GTGGGGATGT  ATCCTGGGAC  1080
1081  AAGTCTTTGT  GTATCGGAGC  CACCTATGAC  ATCACAGACT  CCTGCATCAC  CCACCAGATT  1140
1141  GTTGACCGGC  CTGGGCAGCA  AACTCCTGTC  ATTGGCAGAT  ACTACGTACA  GCCCCAGTGG  1200
1201  GTGTTTGACT  GTGTGAATGC  CCGGCTCCTC  CTCCCTGTGG  CAGAGTACTT  TCCTGGGGTG  1260
1261  CAGCTGCCCC  CACACCTCTC  ACCCTTCGTA  TCTGAGAAGG  AAGGAGATTA  CATTCCCCCT  1320
1321  GAGAAGCTGA  AGCTGCTGGC  TCTGCAGCGG  GGAGAAGACC  CAGGTGAGCT  GGATGAGGAT  1380
1381  GAGGACGATG  AAGAAGATGA  AGATGGTGAC  AACGAAGGTG  ATGGTGATGT  TGCGGGGGAA  1440
1441  AATGAAGAGG  AGGAGGATGT  GGGAGCTGAT  TCAGAGATGG  AGGAGGAAGC  GCACCTGTCA  1500
1501  GCCTTGGAGC  AGCAGAGGCT  GGAAGGGAAG  AAGCCCCAGG  TGGTGGCCGG  CACGGTGAAA  1560
1561  CTGGAAGACA  AGCAGCGGCT  GGCCCAGGAG  GAAGAGAGCG  AGGCCAAGCG  CCTGGCCATC  1620
1621  ATGATGATGA  AAAAGCGCGA  GAAGTACCTT  TACCAAAAGA  TCATGTTTGG  CAAGCGGCGC  1680
1681  AAAATCCGTG  AGGCCAACAA  GCTGGCAGAG  AAAAGGAAAG  CCCATGATGA  CGCTGTGAAG  1740
1741  TCTGAGAAAA  GAGCCAAGAG  GACAAGACCT  GTATGA  1776

▼ KEYWORD

ID
Family
Chromosome
Coiled coil
Complete proteome
Nucleus
Reference proteome
Ribosome biogenesis
rRNA processing
Ubl conjugation

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chromosome
Cellular Component
Nucleolus
Cellular Component
Nucleoplasm
Cellular Component
Preribosome, large subunit precursor
Molecular Function
Ribonucleoprotein complex binding
Biological Process
Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process
Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ora-0780Ornithorhynchus anatinus96.436e-69 225
LLPS-Eqc-0287Equus caballus93.10.0 828
LLPS-Fud-0045Fukomys damarensis92.890.0 813
LLPS-Ran-1347Rattus norvegicus91.150.01000
LLPS-Mum-0112Mus musculus89.830.0 997
LLPS-Fec-1641Felis catus89.660.0 912
LLPS-Caj-0696Callithrix jacchus89.060.0 969
LLPS-Man-1682Macaca nemestrina88.770.0 920
LLPS-Maf-0335Macaca fascicularis88.540.0 962
LLPS-Mup-0516Mustela putorius furo88.540.0 974
LLPS-Rhb-0159Rhinopithecus bieti88.410.0 907
LLPS-Aon-1815Aotus nancymaae88.370.0 947
LLPS-Pat-0154Pan troglodytes88.370.0 961
LLPS-Mam-1301Macaca mulatta88.370.0 961
LLPS-Gog-1465Gorilla gorilla88.190.0 958
LLPS-Pap-0145Pan paniscus88.190.0 954
LLPS-Poa-1516Pongo abelii88.190.0 958
LLPS-Paa-2864Papio anubis88.040.0 956
LLPS-Dio-0166Dipodomys ordii88.040.0 892
LLPS-Hos-0941Homo sapiens88.020.0 958
LLPS-Chs-0903Chlorocebus sabaeus87.870.0 957
LLPS-Mal-1428Mandrillus leucophaeus87.870.0 954
LLPS-Aim-0306Ailuropoda melanoleuca87.720.0 944
LLPS-Ict-1400Ictidomys tridecemlineatus87.690.0 968
LLPS-Cea-1105Cercocebus atys87.20.0 956
LLPS-Cas-0287Carlito syrichta87.00.0 954
LLPS-Caf-1094Canis familiaris86.930.0 919
LLPS-Cap-2241Cavia porcellus86.720.0 943
LLPS-Urm-0873Ursus maritimus86.20.0 952
LLPS-Orc-0707Oryctolagus cuniculus86.110.0 933
LLPS-Otg-2126Otolemur garnettii85.250.0 925
LLPS-Sus-0758Sus scrofa84.120.0 947
LLPS-Gaga-0809Gallus gallus83.30.0 747
LLPS-Meg-0695Meleagris gallopavo83.184e-119 359
LLPS-Loa-0453Loxodonta africana82.675e-174 509
LLPS-Bot-0007Bos taurus81.610.0 915
LLPS-Mod-0195Monodelphis domestica77.840.0 838
LLPS-Dar-1119Danio rerio76.660.0 682
LLPS-Fia-1477Ficedula albicollis74.010.0 763
LLPS-Anp-1086Anas platyrhynchos73.720.0 756
LLPS-Lac-0854Latimeria chalumnae73.720.0 795
LLPS-Anc-1343Anolis carolinensis73.120.0 793
LLPS-Orn-0864Oreochromis niloticus71.380.0 778
LLPS-Pof-1516Poecilia formosa70.490.0 748
LLPS-Orl-0163Oryzias latipes70.450.0 742
LLPS-Scm-1147Scophthalmus maximus70.140.0 767
LLPS-Tar-1198Takifugu rubripes70.090.0 771
LLPS-Icp-0572Ictalurus punctatus69.310.0 725
LLPS-Gaa-0641Gasterosteus aculeatus68.860.0 746
LLPS-Ova-1595Ovis aries68.670.0 675
LLPS-Scf-1034Scleropages formosus67.780.0 744
LLPS-Xim-0230Xiphophorus maculatus67.610.0 756
LLPS-Tag-0397Taeniopygia guttata64.722e-138 414
LLPS-Xet-0822Xenopus tropicalis64.20.0 698
LLPS-Leo-0807Lepisosteus oculatus63.250.0 674
LLPS-Lem-0461Leptosphaeria maculans63.235e-61 207
LLPS-Asm-0130Astyanax mexicanus62.410.0 655
LLPS-Asfu-0888Aspergillus fumigatus59.23e-95 312
LLPS-Trr-0679Trichoderma reesei57.433e-91 301
LLPS-Beb-0466Beauveria bassiana56.851e-89 297
LLPS-Mao-1021Magnaporthe oryzae56.222e-94 310
LLPS-Ten-2154Tetraodon nigroviridis56.040.0 561
LLPS-Blg-0543Blumeria graminis55.651e-89 298
LLPS-Spr-0420Sporisorium reilianum55.65e-92 304
LLPS-Usm-0403Ustilago maydis55.65e-91 301
LLPS-Abg-0538Absidia glauca55.472e-37 144
LLPS-Mua-0044Musa acuminata55.411e-1578.6
LLPS-Nec-0136Neurospora crassa55.081e-91 303
LLPS-Sac-0439Saccharomyces cerevisiae55.04e-89 294
LLPS-Chr-0228Chlamydomonas reinhardtii53.941e-79 274
LLPS-Ved-0371Verticillium dahliae53.72e-92 305
LLPS-Cogr-1320Colletotrichum graminicola53.319e-87 289
LLPS-Drm-1188Drosophila melanogaster51.131e-145 442
LLPS-Scj-0993Schizosaccharomyces japonicus51.092e-147 446
LLPS-Cae-0993Caenorhabditis elegans50.811e-131 403
LLPS-Scp-0355Schizosaccharomyces pombe50.775e-148 447
LLPS-Scc-0277Schizosaccharomyces cryophilus49.259e-144 437
LLPS-Chc-0648Chondrus crispus47.772e-64 229
LLPS-Phn-0195Phaeosphaeria nodorum47.684e-133 411
LLPS-Asni-0879Aspergillus niger47.565e-123 378
LLPS-Pyt-0723Pyrenophora teres47.311e-134 416
LLPS-Tum-0666Tuber melanosporum46.972e-128 396
LLPS-Asf-0574Aspergillus flavus46.951e-129 402
LLPS-Aso-0079Aspergillus oryzae46.951e-129 402
LLPS-Sol-0407Solanum lycopersicum46.869e-117 367
LLPS-Hea-0568Helianthus annuus46.223e-117 367
LLPS-Lep-0477Leersia perrieri46.196e-117 367
LLPS-Nia-0836Nicotiana attenuata46.023e-116 365
LLPS-Sot-0183Solanum tuberosum45.998e-112 354
LLPS-Put-0652Puccinia triticina45.881e-128 399
LLPS-Pug-0913Puccinia graminis45.812e-126 393
LLPS-Php-0063Physcomitrella patens45.744e-121 378
LLPS-Ors-0720Oryza sativa45.747e-115 362
LLPS-Orr-0180Oryza rufipogon45.747e-115 362
LLPS-Asn-0627Aspergillus nidulans45.592e-127 396
LLPS-Pytr-0840Pyrenophora triticirepentis45.514e-114 362
LLPS-Miv-1049Microbotryum violaceum45.315e-134 413
LLPS-Pot-0336Populus trichocarpa45.096e-114 359
LLPS-Cog-0001Colletotrichum gloeosporioides45.081e-123 385
LLPS-Brd-0407Brachypodium distachyon45.032e-114 361
LLPS-Coo-0097Colletotrichum orbiculare44.875e-125 389
LLPS-Mel-0251Melampsora laricipopulina44.865e-129 400
LLPS-Asc-0329Aspergillus clavatus44.744e-122 383
LLPS-Gor-1017Gossypium raimondii44.78e-112 353
LLPS-Orni-0227Oryza nivara44.696e-115 362
LLPS-Orb-0072Oryza barthii44.696e-115 362
LLPS-Ori-0536Oryza indica44.694e-115 362
LLPS-Orgl-1350Oryza glumaepatula44.696e-115 362
LLPS-Orbr-0271Oryza brachyantha44.693e-117 367
LLPS-Sob-0002Sorghum bicolor44.696e-112 355
LLPS-Org-0941Oryza glaberrima44.696e-115 362
LLPS-Dos-0821Dothistroma septosporum44.655e-119 375
LLPS-Thc-0095Theobroma cacao44.575e-112 354
LLPS-Brn-1473Brassica napus44.554e-112 354
LLPS-Sem-0608Selaginella moellendorffii44.521e-125 390
LLPS-Zem-1146Zea mays44.475e-112 355
LLPS-Art-1226Arabidopsis thaliana44.444e-113 357
LLPS-Bro-0489Brassica oleracea44.421e-111 353
LLPS-Tra-1962Triticum aestivum44.394e-113 357
LLPS-Arl-1602Arabidopsis lyrata44.345e-113 356
LLPS-Hov-0492Hordeum vulgare44.326e-114 359
LLPS-Ast-0309Aspergillus terreus44.292e-124 389
LLPS-Asg-0126Ashbya gossypii44.155e-118 370
LLPS-Dac-1167Daucus carota43.981e-117 369
LLPS-Fuo-0159Fusarium oxysporum43.923e-113 359
LLPS-Zyt-0100Zymoseptoria tritici43.812e-123 387
LLPS-Orp-0048Oryza punctata43.816e-114 359
LLPS-Nef-0796Neosartorya fischeri43.612e-125 391
LLPS-Mae-1325Manihot esculenta43.589e-110 348
LLPS-Amt-0313Amborella trichopoda43.561e-112 356
LLPS-Viv-0119Vitis vinifera43.398e-111 351
LLPS-Brr-2328Brassica rapa43.272e-111 352
LLPS-Prp-2236Prunus persica43.254e-114 359
LLPS-Fuv-0564Fusarium verticillioides43.185e-113 358
LLPS-Trv-0687Trichoderma virens43.172e-119 375
LLPS-Cus-0891Cucumis sativus42.924e-98 318
LLPS-Fus-0093Fusarium solani42.898e-113 358
LLPS-Scs-0117Sclerotinia sclerotiorum42.712e-121 381
LLPS-Sei-0522Setaria italica42.685e-110 350
LLPS-Vir-0683Vigna radiata42.517e-107 341
LLPS-Kop-0382Komagataella pastoris42.489e-113 355
LLPS-Glm-0925Glycine max42.442e-108 345
LLPS-Met-0229Medicago truncatula42.321e-108 346
LLPS-Via-0755Vigna angularis42.321e-107 342
LLPS-Map-0963Magnaporthe poae42.085e-124 388
LLPS-Gag-0405Gaeumannomyces graminis41.942e-121 381
LLPS-Yal-0420Yarrowia lipolytica41.793e-111 352
LLPS-Phv-1631Phaseolus vulgaris41.793e-104 334
LLPS-Osl-0182Ostreococcus lucimarinus41.615e-116 363
LLPS-Cym-0098Cyanidioschyzon merolae41.413e-51 192
LLPS-Crn-0272Cryptococcus neoformans39.875e-96 313
LLPS-Gas-0018Galdieria sulphuraria39.766e-60 211