LLPS-Mea-2245
Gli3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | transcriptional activator GLI3 |
| Gene Name: | Gli3 |
| Ensembl Gene: | ENSMAUG00000010007.1 |
| Ensembl Protein: | ENSMAUP00000008627.1 |
| Organism: | Mesocricetus auratus |
| Taxa ID: | 10036 |
| LLPS Type: | Client |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMAUT00000012457.1 | ENSMAUP00000008627.1 |
| UniProt | A0A1U8BS55, A0A1U8BS55_MESAU | |
| RefSeq | , XM_013114613.1 | , XP_012970067.1, XP_012970067.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEAQSHSSTT TERKKAENSI GKCSTRTDVS EKAVASSTTS NEDESPGQIY HRERRNAITM 60 61 QPQSVQGLSK ISEEPSTSSD ERASLIKKEI HGSLPHLAEP SLPYRGTVFA MDPRNGYMEP 120 121 HYHPPHLFPA FHPPVPIDAR HHEGRYHYDP SPIPPLHVPS ALSSSPTYPD LPFIRISPHR 180 181 NPTAASESPF SPPHPYINPY MDYIRSLHSS PSLSMISAAR GLSPTDAPHA GVSPAEYYHQ 240 241 MALLTGQRSP YADILPSAAT AGAGAIHMEY LHAMDSARFP SPRLSARPSR KRTLSISPLS 300 301 DHSFDLQTMI RTSPNSLVTI LNNSRSSSSA SGSYGHLSAS AISPALSFTY PSAPVSLHMH 360 361 QQILSRQQSL GSAFGHSPPL IHPAPTFPTQ RPIPGIPTVL NPVQVSSGPS ESSQNKPTSE 420 421 SAVSSTGDPM HNKRSKIKPD EDLPSPGSRG QQEQPEGTTL VKEEGDKDES KQEPEVIYET 480 481 NCHWEGCTRE FDTQDQLVHH INNDHIHGEK KEFVCRWLDC SREQKPFKAQ YMLVVHMRRH 540 541 TGEKPHKCTF EGCTKAYSRL ENLKTHLRSH TGEKPYVCEH EGCNKAFSNA SDRAKHQNRT 600 601 HSNEKPYVCK IPGCTKRYTD PSSLRKHVKT VHGPEAHVTK KQRGDMHPRP PPPRDSGSHS 660 661 QSRSPSRPTQ GAFAEQKELS NTTSKREECL QVKTVKAEKP MTSQPSPGGQ SSCSSQQSPI 720 721 SNYSNSGLEL PLNDGGSVAD LSAIDETPIM DSTISTATTA LALQARRNPA GTKWMEHIKL 780 781 ERLKQVNGMF PRLNPILPSK APAVSPLIGN GTQSNNNYSS GGPGTILPSR SDLSGVDFTV 840 841 LNTLNRRDSS TSTISSAYLS SRRSSGISPC FSSRRSSEAS QAEGRPQNVS VADSYDPIST 900 901 DASRRSSEAS QGDGLPSLLS LTPVQQYRLK AKYAAATGGP PPTPLPHMEK LSLKTRMALL 960 961 GEGRDSGVTL PPVHPPRRCS DGGGQAYNRR HLLPHDALAN SVRRASDPVR TVSENMSLPR 1020 1021 VQRFSSLNSF NPPSLPPSVE KRSLVLQNYT RPESSQQPRY FQASPCPPSI TENVALEALT 1080 1081 MDADANLNDE DFLPDDVVQY LNSQNQTGYG QLQRAISEDS KVAHGPEDLD LPGLPDSHVG 1140 1141 QQYPAMEQPC PEGSKTDLPI QWNEVSSGSS DLSSSKLKCG QRPTIQQARA FGLYNNMVVH 1200 1201 PQNSWKVGTG PAGGYQTLGE NGSTYSGPEH FVIHSGDGPG SNGNAFHEQP YKTQQYGSQL 1260 1261 NRQPLTSSVL DNACGAGIQG SKLKGNALQE NGGLLDFGLS TAPNELTGNS VNGIQTQDQM 1320 1321 GQGYIAHQLL SGSMQHQGAS RPGQQILGQV GATSHINIYQ GTESCLPGTQ DNSNQPASVA 1380 1381 IVRGYQPCAS YGGSRRQAMP RGSLTLQQGQ LSDVSQTSRV NSIKMEAQGQ SQQLCSNVEN 1440 1441 YSGQFYGQTV GFSQQDRKAG SFSLSDASCL LQGNGTENSE LLSPGANQVT STVDSFESHD 1500 1501 LEGVQIDFDA IIDDGDHTSL MSGALSPSII QNLSHSSSRL TTPRAPLPFP PLPMSTTNMA 1560 1561 IGDMSSLLTS LAEESKFLAV MQ 1582 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAGGCCC AGTCCCACAG CTCCACAACC ACTGAGAGGA AGAAAGCTGA GAATTCCATT 60 61 GGAAAATGTT CCACAAGGAC AGATGTCAGT GAGAAGGCGG TGGCCTCCAG TACCACTTCG 120 121 AATGAGGATG AAAGTCCTGG ACAGATCTAT CATCGAGAGA GAAGAAACGC AATCACTATG 180 181 CAGCCTCAGA GTGTGCAGGG GCTCAGCAAA ATCAGTGAAG AACCCTCAAC ATCTAGTGAT 240 241 GAGAGGGCTT CATTGATCAA GAAGGAGATC CATGGGTCTC TACCGCATCT GGCAGAGCCC 300 301 TCACTCCCTT ATCGTGGGAC TGTGTTTGCT ATGGACCCCC GAAATGGTTA CATGGAGCCT 360 361 CACTACCACC CTCCTCATCT TTTCCCTGCC TTCCATCCTC CTGTACCAAT TGATGCCAGA 420 421 CATCATGAGG GCCGTTACCA TTATGATCCA TCTCCTATTC CTCCATTACA TGTGCCTTCT 480 481 GCCTTATCTA GTAGCCCGAC ATATCCAGAC CTGCCCTTCA TTAGGATCTC CCCACACCGT 540 541 AACCCCACTG CGGCTTCAGA GTCTCCCTTT AGCCCCCCAC ATCCTTACAT CAACCCGTAT 600 601 ATGGACTACA TCCGCTCCTT GCACAGCAGC CCATCTCTCT CCATGATCTC AGCTGCCCGA 660 661 GGCCTGAGCC CTACAGACGC CCCCCATGCT GGAGTCAGCC CAGCAGAATA CTATCACCAG 720 721 ATGGCTCTGC TGACAGGCCA GCGAAGCCCC TATGCAGACA TCCTTCCCTC AGCTGCCACC 780 781 GCCGGTGCAG GGGCCATCCA CATGGAGTAC CTTCATGCCA TGGATAGCGC CAGATTTCCT 840 841 AGCCCCAGAC TGTCAGCTAG GCCCAGCCGA AAACGCACAC TGTCCATATC ACCACTGTCA 900 901 GATCATAGCT TCGACCTTCA GACCATGATA AGAACATCTC CTAACTCCCT GGTCACAATT 960 961 CTCAATAATT CCCGTAGCAG CTCTTCAGCG AGTGGTTCCT ATGGGCACTT ATCGGCAAGT 1020 1021 GCAATCAGCC CTGCTTTGAG CTTCACCTAC CCCTCTGCCC CTGTGTCTCT CCATATGCAT 1080 1081 CAACAAATCC TAAGCCGACA GCAAAGCTTA GGCTCAGCAT TTGGACACAG CCCTCCACTC 1140 1141 ATCCACCCTG CTCCAACATT TCCAACACAG AGACCTATCC CTGGGATCCC AACGGTTCTC 1200 1201 AACCCTGTCC AAGTCAGCTC TGGCCCTTCT GAGTCCTCAC AGAACAAGCC CACAAGTGAG 1260 1261 TCTGCAGTGA GCAGCACCGG CGATCCTATG CATAATAAAC GGTCCAAGAT CAAACCCGAT 1320 1321 GAAGACCTCC CCAGTCCAGG GTCACGGGGA CAGCAGGAAC AGCCTGAAGG AACAACCCTA 1380 1381 GTCAAGGAGG AAGGGGACAA AGATGAAAGC AAGCAGGAGC CTGAAGTCAT CTATGAGACA 1440 1441 AACTGCCACT GGGAAGGCTG CACAAGGGAG TTCGACACCC AGGATCAGCT TGTGCATCAT 1500 1501 ATCAATAATG ACCACATTCA TGGAGAAAAG AAGGAATTTG TGTGTCGCTG GCTTGATTGC 1560 1561 TCAAGAGAGC AGAAACCCTT CAAAGCTCAG TACATGTTGG TAGTGCACAT GAGAAGACAT 1620 1621 ACTGGCGAGA AGCCTCACAA ATGTACATTT GAAGGTTGCA CAAAAGCCTA CTCGAGACTA 1680 1681 GAAAACCTGA AAACGCACTT GAGATCTCAC ACTGGAGAGA AGCCATACGT CTGTGAGCAT 1740 1741 GAGGGCTGCA ACAAGGCTTT CTCCAATGCT TCAGATCGGG CCAAGCACCA AAACAGAACA 1800 1801 CATTCCAATG AGAAACCGTA TGTATGCAAA ATCCCTGGCT GCACCAAACG TTACACAGAC 1860 1861 CCCAGTTCTC TCCGGAAACA TGTGAAGACT GTGCATGGTC CTGAGGCTCA TGTCACCAAG 1920 1921 AAGCAGCGTG GGGACATGCA CCCTCGGCCT CCGCCCCCAA GGGATTCTGG CAGCCACTCA 1980 1981 CAGTCCAGGT CCCCCAGCAG GCCGACTCAG GGAGCCTTTG CTGAACAGAA GGAGTTGAGC 2040 2041 AACACTACCT CAAAGCGGGA AGAATGCCTC CAGGTGAAGA CAGTCAAGGC TGAGAAGCCC 2100 2101 ATGACATCTC AGCCAAGCCC TGGTGGTCAG TCTTCATGCA GCAGCCAACA GTCCCCCATC 2160 2161 AGCAACTATT CCAACAGTGG GCTCGAGCTT CCTCTGAATG ATGGAGGTAG TGTAGCAGAC 2220 2221 CTCAGTGCCA TCGATGAAAC CCCAATCATG GACTCGACCA TTTCCACGGC AACCACAGCC 2280 2281 CTTGCTTTGC AAGCCAGGAG AAACCCGGCA GGGACCAAAT GGATGGAGCA TATCAAACTT 2340 2341 GAAAGGCTAA AACAAGTGAA TGGAATGTTT CCAAGACTGA ACCCTATTCT ACCCTCCAAA 2400 2401 GCCCCTGCGG TGTCTCCTCT TATAGGAAAT GGCACACAGT CCAATAACAA CTATAGTTCA 2460 2461 GGCGGGCCCG GGACCATCCT CCCGAGCAGA AGTGACCTGT CTGGTGTTGA CTTCACCGTG 2520 2521 CTGAACACGC TCAACAGGAG GGACAGCAGC ACCAGCACCA TCAGCTCTGC CTACCTGAGT 2580 2581 AGCCGCAGAT CCTCGGGCAT CTCCCCCTGC TTTTCCAGCC GCAGGTCCAG TGAGGCGTCC 2640 2641 CAGGCTGAAG GACGACCCCA GAATGTGAGT GTGGCTGATT CCTACGACCC TATCTCCACA 2700 2701 GATGCCTCAC GGAGGTCCAG CGAGGCCAGC CAGGGCGATG GGCTGCCCAG TCTGCTCAGC 2760 2761 CTCACCCCTG TGCAGCAGTA CCGCCTCAAG GCCAAGTACG CTGCTGCCAC TGGTGGTCCA 2820 2821 CCGCCTACAC CCCTGCCACA CATGGAAAAG TTGAGCCTGA AGACCAGGAT GGCCTTGCTT 2880 2881 GGGGAGGGTA GGGACTCGGG GGTGACCCTG CCTCCAGTTC ATCCTCCTCG GAGGTGCAGT 2940 2941 GATGGAGGAG GCCAGGCATA CAACCGGCGT CACCTGCTGC CTCATGATGC ACTAGCAAAC 3000 3001 AGTGTGAGGA GAGCCAGCGA CCCTGTGAGG ACAGTCTCCG AGAACATGTC ACTTCCCAGG 3060 3061 GTTCAACGCT TCAGCAGCCT CAACAGCTTC AATCCTCCAA GTTTGCCTCC GTCGGTGGAA 3120 3121 AAGCGTAGCT TAGTGTTGCA AAATTATACC CGACCAGAGA GCAGCCAGCA GCCCCGATAC 3180 3181 TTCCAAGCGT CTCCTTGTCC TCCCAGCATC ACAGAAAATG TTGCCCTGGA GGCCCTGACC 3240 3241 ATGGATGCTG ATGCCAACTT GAATGATGAA GATTTCCTGC CAGATGATGT AGTACAGTAT 3300 3301 TTAAATTCCC AGAACCAAAC AGGGTATGGA CAATTACAGA GGGCCATCTC TGAAGACAGC 3360 3361 AAAGTAGCCC ATGGGCCAGA GGACTTGGAC CTACCAGGGC TGCCAGACAG TCATGTTGGC 3420 3421 CAGCAGTACC CGGCTATGGA GCAGCCCTGC CCTGAGGGTA GCAAAACTGA TTTGCCTATC 3480 3481 CAGTGGAACG AAGTCAGTTC TGGAAGCTCT GACCTGTCAT CCTCCAAGCT GAAATGTGGT 3540 3541 CAGCGCCCTA CCATACAGCA GGCTCGAGCC TTTGGCTTAT ACAACAATAT GGTGGTGCAC 3600 3601 CCACAGAATT CATGGAAGGT TGGGACTGGT CCAGCTGGGG GATATCAGAC CCTCGGGGAG 3660 3661 AATGGCAGTA CCTACAGTGG CCCAGAGCAC TTTGTCATTC ACAGTGGGGA TGGCCCTGGC 3720 3721 TCAAATGGAA ATGCTTTCCA TGAACAGCCC TATAAGACCC AGCAGTATGG GAGCCAGCTC 3780 3781 AACAGGCAGC CACTGACTTC CAGTGTACTA GATAATGCCT GTGGTGCTGG AATTCAAGGG 3840 3841 TCCAAGCTGA AAGGCAACGC CTTGCAAGAG AATGGGGGTT TGCTAGATTT TGGTCTGTCC 3900 3901 ACGGCACCAA ATGAATTAAC TGGCAACTCA GTGAATGGCA TACAAACCCA AGATCAAATG 3960 3961 GGACAGGGAT ACATTGCTCA TCAGCTACTC AGCGGCAGCA TGCAACACCA GGGGGCCAGC 4020 4021 CGCCCTGGTC AACAGATACT AGGGCAGGTT GGTGCTACCT CACATATCAA CATCTATCAA 4080 4081 GGGACAGAAA GCTGCCTGCC AGGGACTCAG GACAACAGCA ACCAACCAGC GAGCGTGGCA 4140 4141 ATTGTCCGGG GCTACCAGCC CTGTGCCAGC TATGGGGGCA GTAGGCGTCA GGCAATGCCA 4200 4201 AGGGGCAGCC TCACTCTGCA GCAAGGACAG CTCAGCGATG TGAGTCAGAC GAGCAGGGTG 4260 4261 AACAGCATCA AGATGGAGGC ACAAGGGCAG TCCCAGCAGC TCTGCTCTAA TGTGGAGAAT 4320 4321 TACTCTGGTC AGTTCTATGG CCAAACCGTG GGCTTCAGTC AGCAAGACAG GAAAGCCGGT 4380 4381 TCCTTTTCCC TTTCAGATGC CAGCTGCCTG CTCCAAGGGA ATGGCACTGA AAACTCTGAG 4440 4441 TTACTTTCCC CAGGTGCTAA CCAAGTGACA AGCACAGTTG ACAGCTTTGA GAGTCATGAC 4500 4501 CTAGAAGGTG TGCAGATTGA TTTTGACGCC ATAATAGACG ATGGGGACCA TACCAGCCTG 4560 4561 ATGTCCGGGG CCTTGAGCCC AAGTATCATT CAGAACCTTT CCCACAGCTC CTCCCGTCTC 4620 4621 ACCACACCGC GGGCACCCCT CCCATTCCCG CCCCTGCCCA TGAGCACCAC CAACATGGCT 4680 4681 ATCGGGGATA TGAGTTCTTT GCTGACCTCC CTTGCAGAAG AAAGCAAGTT CCTTGCAGTT 4740 4741 ATGCAGTAG 4749 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mam-4496 | Macaca mulatta | 96.22 | 0.0 | 1258 |
| LLPS-Mum-1902 | Mus musculus | 95.2 | 0.0 | 2651 |
| LLPS-Ran-2373 | Rattus norvegicus | 94.88 | 0.0 | 2631 |
| LLPS-Urm-2699 | Ursus maritimus | 93.39 | 0.0 | 829 |
| LLPS-Dio-3637 | Dipodomys ordii | 91.33 | 0.0 | 1464 |
| LLPS-Ict-4400 | Ictidomys tridecemlineatus | 90.46 | 0.0 | 2526 |
| LLPS-Orc-2703 | Oryctolagus cuniculus | 88.0 | 0.0 | 2372 |
| LLPS-Aon-1268 | Aotus nancymaae | 87.43 | 0.0 | 2425 |
| LLPS-Pap-0683 | Pan paniscus | 87.24 | 0.0 | 2420 |
| LLPS-Hos-3666 | Homo sapiens | 87.18 | 0.0 | 2417 |
| LLPS-Gog-0245 | Gorilla gorilla | 87.11 | 0.0 | 2416 |
| LLPS-Pat-0152 | Pan troglodytes | 87.11 | 0.0 | 2415 |
| LLPS-Poa-0290 | Pongo abelii | 87.05 | 0.0 | 2419 |
| LLPS-Mal-2576 | Mandrillus leucophaeus | 86.8 | 0.0 | 2407 |
| LLPS-Caj-1963 | Callithrix jacchus | 86.8 | 0.0 | 2404 |
| LLPS-Man-3649 | Macaca nemestrina | 86.73 | 0.0 | 2405 |
| LLPS-Cea-0611 | Cercocebus atys | 86.67 | 0.0 | 2402 |
| LLPS-Paa-0499 | Papio anubis | 86.61 | 0.0 | 2397 |
| LLPS-Maf-3741 | Macaca fascicularis | 86.48 | 0.0 | 2404 |
| LLPS-Cap-4439 | Cavia porcellus | 86.19 | 0.0 | 2360 |
| LLPS-Fud-4432 | Fukomys damarensis | 86.14 | 0.0 | 2349 |
| LLPS-Chs-1820 | Chlorocebus sabaeus | 86.13 | 0.0 | 2191 |
| LLPS-Bot-4138 | Bos taurus | 85.67 | 0.0 | 2313 |
| LLPS-Loa-3954 | Loxodonta africana | 85.34 | 0.0 | 2363 |
| LLPS-Otg-2531 | Otolemur garnettii | 85.23 | 0.0 | 2118 |
| LLPS-Aim-0887 | Ailuropoda melanoleuca | 85.18 | 0.0 | 2326 |
| LLPS-Eqc-2418 | Equus caballus | 84.98 | 0.0 | 2329 |
| LLPS-Ova-2004 | Ovis aries | 84.86 | 0.0 | 1750 |
| LLPS-Tut-2392 | Tursiops truncatus | 84.62 | 0.0 | 2249 |
| LLPS-Mup-3013 | Mustela putorius furo | 84.48 | 0.0 | 2304 |
| LLPS-Fec-3641 | Felis catus | 83.46 | 0.0 | 2283 |
| LLPS-Rhb-0113 | Rhinopithecus bieti | 83.05 | 0.0 | 2223 |
| LLPS-Sus-4774 | Sus scrofa | 82.99 | 0.0 | 2221 |
| LLPS-Myl-4290 | Myotis lucifugus | 82.96 | 0.0 | 2047 |
| LLPS-Caf-4687 | Canis familiaris | 82.7 | 0.0 | 2236 |
| LLPS-Pes-3458 | Pelodiscus sinensis | 77.04 | 0.0 | 2041 |
| LLPS-Anp-2023 | Anas platyrhynchos | 76.91 | 0.0 | 1956 |
| LLPS-Ora-3085 | Ornithorhynchus anatinus | 76.74 | 0.0 | 1920 |
| LLPS-Gaga-0462 | Gallus gallus | 76.7 | 0.0 | 1998 |
| LLPS-Fia-0295 | Ficedula albicollis | 76.51 | 0.0 | 2009 |
| LLPS-Tag-1000 | Taeniopygia guttata | 76.31 | 0.0 | 1939 |
| LLPS-Meg-3122 | Meleagris gallopavo | 74.78 | 0.0 | 1792 |
| LLPS-Anc-1929 | Anolis carolinensis | 73.99 | 0.0 | 1810 |
| LLPS-Mod-2021 | Monodelphis domestica | 73.56 | 0.0 | 1434 |
| LLPS-Leo-3007 | Lepisosteus oculatus | 71.31 | 0.0 | 1426 |
| LLPS-Gaa-0409 | Gasterosteus aculeatus | 71.08 | 0.0 | 995 |
| LLPS-Xet-0119 | Xenopus tropicalis | 69.08 | 0.0 | 1710 |
| LLPS-Lac-1942 | Latimeria chalumnae | 66.1 | 0.0 | 1550 |
| LLPS-Xim-2148 | Xiphophorus maculatus | 63.19 | 5e-59 | 226 |
| LLPS-Pof-0395 | Poecilia formosa | 63.19 | 1e-59 | 226 |
| LLPS-Scf-1108 | Scleropages formosus | 62.87 | 3e-61 | 228 |
| LLPS-Orl-0799 | Oryzias latipes | 62.58 | 7e-58 | 222 |
| LLPS-Tar-1970 | Takifugu rubripes | 61.76 | 2e-60 | 228 |
| LLPS-Orn-1952 | Oreochromis niloticus | 60.87 | 3e-58 | 222 |
| LLPS-Icp-2000 | Ictalurus punctatus | 59.66 | 7e-60 | 226 |
| LLPS-Scm-1837 | Scophthalmus maximus | 59.11 | 0.0 | 1118 |
| LLPS-Ten-1940 | Tetraodon nigroviridis | 57.42 | 0.0 | 910 |
| LLPS-Cas-0752 | Carlito syrichta | 56.9 | 3e-53 | 205 |
| LLPS-Dar-2577 | Danio rerio | 56.6 | 0.0 | 1040 |
| LLPS-Drm-2364 | Drosophila melanogaster | 56.58 | 5e-49 | 186 |
| LLPS-Nol-1991 | Nomascus leucogenys | 56.21 | 5e-49 | 189 |
| LLPS-Asm-0713 | Astyanax mexicanus | 53.66 | 6e-49 | 188 |