• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-1091
Tlk1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: serine/threonine-protein kinase tousled-like 1 isoform X1
Gene Name: Tlk1
Ensembl Gene: ENSMAUG00000020231.1
Ensembl Protein: ENSMAUP00000022942.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSVQSSSGSL  EGPPSWSRLS  TSPTPGSAAA  ARSLLNHTPP  SGRPREGAMD  ELHSLDPRRQ  60
61    ELLEARFTGV  ATGSTGSTGS  CSVGAKASTN  NESSNHSFGS  LGSLSDKESE  TPEKKQSESS  120
121   RGRKRKAESQ  NESSQGKSIG  GRGHKISDYF  EYQGGNGSSP  VRGIPPAIRS  PQNSHSHSTP  180
181   SSSVRPNSPS  PTALAFGDHP  VIQPKQLSFK  ITQTDLTMLK  LAALESNKNQ  DLEKKEGRID  240
241   DLLRANCDLR  RQIDDQQKLL  EKYKERLNKC  ISMSKKLLIE  KSTQEKLSSR  EKSMQDRLRL  300
301   GHFTTVRHGA  SFTEQWTDGF  AFQNLVKQQE  WVNQQREDIE  RQRKLLAKRK  PPTANNSQAP  360
361   ATNSEPKQRK  NKAVNGAEND  PFVRPNLPQL  LTLAEYHEQE  EIFKLRLGHL  KKEEAEIQAE  420
421   LERLERVRNL  HIRELKRINN  EDNSQFKDHP  TLNERYLLLH  LLGRGGFSEV  YKAFDLYEQR  480
481   YAAVKIHQLN  KSWRDEKKEN  YHKHACREYR  IHKELDHPRI  VKLYDYFSLD  TDTFCTVLEY  540
541   CEGNDLDFYL  KQHKLMSEKE  ARSIVMQIVN  ALRYLNEIKP  PIIHYDLKPG  NILLVDGTAC  600
601   GEIKITDFGL  SKIMDDDSYG  VDGMDLTSQG  AGTYWYLPPE  CFVVGKEPPK  ISNKVDVWSV  660
661   GVIFFQCLYG  RKPFGHNQSQ  QDILQENTIL  KATEVQFPVK  PVVSSEAKAF  IRRCLAYRKE  720
721   DRFDVHQLAN  DPYLLPHMRR  SNSSGNLHMS  GLTATPAPPS  SSVITY  766
Nucleotide CDS Sequence (FASTA)
1     ATGAGTGTCC  AAAGTAGCAG  TGGAAGTTTG  GAGGGGCCGC  CATCTTGGTC  CCGGCTCTCC  60
61    ACGTCTCCAA  CCCCGGGCTC  GGCGGCGGCG  GCCAGGTCCC  TGCTGAATCA  CACGCCGCCA  120
121   TCCGGGAGGC  CCAGGGAAGG  TGCAATGGAT  GAGCTTCACA  GTCTGGATCC  AAGAAGGCAA  180
181   GAATTACTGG  AAGCGAGATT  TACTGGAGTT  GCGACAGGGA  GCACCGGGAG  TACCGGGAGT  240
241   TGCAGTGTTG  GAGCGAAAGC  CTCAACAAAT  AATGAAAGTT  CTAATCACAG  TTTTGGAAGC  300
301   TTAGGATCTT  TAAGTGACAA  AGAATCAGAG  ACACCAGAGA  AGAAACAATC  TGAGTCATCC  360
361   AGGGGAAGAA  AGAGAAAAGC  AGAAAGTCAG  AATGAAAGTA  GTCAGGGAAA  AAGTATTGGA  420
421   GGACGTGGCC  ACAAGATTAG  TGACTATTTT  GAATATCAGG  GTGGAAATGG  CTCAAGTCCA  480
481   GTAAGAGGCA  TACCTCCTGC  AATCCGTTCT  CCGCAAAACT  CACACTCACA  TTCCACTCCT  540
541   TCCTCATCTG  TTCGGCCGAA  TAGTCCTTCT  CCTACTGCAT  TAGCTTTTGG  GGACCACCCT  600
601   GTTATACAAC  CAAAGCAGTT  ATCCTTTAAG  ATCACTCAGA  CTGATCTTAC  AATGCTGAAA  660
661   TTGGCAGCAT  TAGAAAGTAA  TAAGAATCAG  GACCTGGAAA  AGAAGGAAGG  TCGAATAGAT  720
721   GATTTGCTCA  GGGCCAACTG  TGATCTCAGG  CGGCAAATAG  ATGATCAACA  AAAATTACTT  780
781   GAAAAATACA  AAGAACGATT  AAATAAGTGC  ATATCAATGA  GCAAGAAACT  TCTTATTGAA  840
841   AAGAGTACAC  AAGAAAAATT  GTCAAGCAGA  GAGAAGAGTA  TGCAAGACCG  GTTACGCCTT  900
901   GGGCACTTTA  CAACAGTTAG  ACATGGCGCT  TCTTTTACTG  AACAGTGGAC  AGATGGTTTT  960
961   GCATTTCAAA  ATCTTGTGAA  ACAACAAGAA  TGGGTGAATC  AACAAAGGGA  AGATATTGAA  1020
1021  CGGCAAAGGA  AACTTCTAGC  CAAACGCAAA  CCTCCCACAG  CTAATAATTC  TCAGGCACCT  1080
1081  GCTACCAATT  CTGAACCAAA  ACAAAGAAAA  AACAAGGCAG  TCAACGGAGC  AGAAAATGAT  1140
1141  CCCTTTGTTA  GGCCAAATTT  ACCACAACTG  CTGACTCTGG  CAGAATATCA  TGAACAAGAG  1200
1201  GAAATTTTCA  AACTTAGACT  AGGACATCTC  AAAAAGGAAG  AGGCCGAAAT  CCAGGCAGAA  1260
1261  TTGGAGCGTT  TGGAAAGAGT  CAGGAATCTT  CACATACGGG  AGCTCAAGAG  AATAAACAAT  1320
1321  GAGGATAATT  CACAGTTCAA  AGATCATCCA  ACATTAAATG  AAAGATATTT  ATTACTTCAT  1380
1381  CTGCTTGGAA  GAGGTGGCTT  TAGTGAGGTG  TATAAGGCTT  TTGACTTGTA  TGAACAAAGA  1440
1441  TACGCTGCTG  TGAAGATCCA  CCAGCTTAAT  AAAAGCTGGA  GAGATGAAAA  AAAAGAAAAC  1500
1501  TACCACAAAC  ATGCCTGCAG  AGAGTATCGA  ATCCACAAGG  AGCTAGATCA  CCCCAGAATA  1560
1561  GTTAAACTTT  ATGATTACTT  CTCCTTGGAT  ACAGATACGT  TTTGTACAGT  GCTGGAGTAC  1620
1621  TGTGAAGGCA  ATGACTTGGA  CTTCTACCTG  AAGCAGCACA  AGTTGATGTC  TGAGAAAGAA  1680
1681  GCTCGGTCTA  TTGTGATGCA  GATAGTGAAT  GCCCTACGAT  ATCTCAATGA  GATCAAACCT  1740
1741  CCTATTATAC  ATTATGACCT  TAAGCCAGGA  AATATCCTTT  TGGTAGATGG  AACGGCTTGT  1800
1801  GGAGAAATCA  AAATCACTGA  CTTTGGTCTG  TCCAAGATTA  TGGATGATGA  TAGCTATGGT  1860
1861  GTAGATGGAA  TGGATCTGAC  TTCCCAAGGG  GCAGGCACTT  ACTGGTATTT  GCCTCCTGAG  1920
1921  TGCTTTGTAG  TTGGAAAAGA  GCCACCAAAG  ATTTCCAACA  AGGTTGATGT  TTGGTCAGTT  1980
1981  GGAGTCATCT  TCTTTCAGTG  TCTCTATGGT  AGAAAACCAT  TTGGTCACAA  TCAATCTCAA  2040
2041  CAAGACATTC  TCCAGGAAAA  CACAATACTA  AAAGCCACAG  AAGTCCAGTT  CCCTGTAAAA  2100
2101  CCAGTTGTAA  GCAGTGAAGC  CAAGGCCTTC  ATAAGACGCT  GTTTGGCTTA  CCGAAAAGAA  2160
2161  GATCGATTTG  ATGTGCACCA  GCTGGCAAAT  GACCCTTACC  TTCTGCCACA  CATGCGAAGA  2220
2221  TCCAATTCTT  CAGGAAACCT  ACACATGTCT  GGGCTGACAG  CAACTCCTGC  ACCTCCTTCT  2280
2281  TCAAGTGTGA  TCACTTACTG  A  2301

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-2715Rattus norvegicus99.480.01435
LLPS-Mum-1538Mus musculus99.090.01429
LLPS-Mup-4486Mustela putorius furo98.830.01429
LLPS-Urm-1659Ursus maritimus98.750.01360
LLPS-Ict-0664Ictidomys tridecemlineatus98.750.01363
LLPS-Aim-3832Ailuropoda melanoleuca98.750.01365
LLPS-Cap-3984Cavia porcellus98.690.01276
LLPS-Poa-2436Pongo abelii98.620.01218
LLPS-Caf-0875Canis familiaris98.610.01363
LLPS-Fud-2236Fukomys damarensis98.610.01362
LLPS-Orc-3158Oryctolagus cuniculus98.440.01423
LLPS-Aon-2916Aotus nancymaae98.430.01422
LLPS-Caj-2665Callithrix jacchus98.430.01422
LLPS-Chs-1175Chlorocebus sabaeus98.320.01271
LLPS-Nol-2388Nomascus leucogenys98.30.01422
LLPS-Ova-0978Ovis aries98.190.01354
LLPS-Bot-3315Bos taurus98.070.01155
LLPS-Myl-2436Myotis lucifugus97.920.01357
LLPS-Pap-4710Pan paniscus97.410.01414
LLPS-Maf-2320Macaca fascicularis97.40.01360
LLPS-Loa-1170Loxodonta africana97.390.01415
LLPS-Sah-3328Sarcophilus harrisii97.220.01344
LLPS-Cas-2471Carlito syrichta96.740.01425
LLPS-Ora-1752Ornithorhynchus anatinus96.720.01359
LLPS-Sus-3715Sus scrofa96.480.01391
LLPS-Mod-3273Monodelphis domestica96.10.01401
LLPS-Otg-4739Otolemur garnettii95.950.01399
LLPS-Anp-0998Anas platyrhynchos95.690.01350
LLPS-Hos-3468Homo sapiens95.680.01409
LLPS-Pat-3347Pan troglodytes95.680.01409
LLPS-Fec-1326Felis catus95.620.01232
LLPS-Man-0792Macaca nemestrina95.550.01407
LLPS-Cea-3730Cercocebus atys95.550.01407
LLPS-Gog-4542Gorilla gorilla95.550.01407
LLPS-Eqc-1957Equus caballus95.320.01413
LLPS-Mal-1611Mandrillus leucophaeus94.690.01358
LLPS-Fia-3803Ficedula albicollis94.440.01339
LLPS-Pes-1262Pelodiscus sinensis94.310.01209
LLPS-Tag-0479Taeniopygia guttata94.260.01298
LLPS-Anc-3175Anolis carolinensis93.90.01330
LLPS-Mam-3467Macaca mulatta93.590.01348
LLPS-Dio-2942Dipodomys ordii93.480.01377
LLPS-Rhb-2674Rhinopithecus bieti93.010.01351
LLPS-Gaga-1100Gallus gallus92.890.01370
LLPS-Xet-0629Xenopus tropicalis92.220.01288
LLPS-Lac-2333Latimeria chalumnae88.910.0 796
LLPS-Pof-3396Poecilia formosa87.890.01204
LLPS-Icp-2376Ictalurus punctatus87.110.01187
LLPS-Leo-1054Lepisosteus oculatus87.080.01256
LLPS-Ten-3512Tetraodon nigroviridis86.750.01192
LLPS-Orn-1670Oreochromis niloticus86.710.01197
LLPS-Scf-2073Scleropages formosus86.540.01236
LLPS-Tar-2923Takifugu rubripes86.40.01185
LLPS-Orl-1399Oryzias latipes86.120.01189
LLPS-Xim-0382Xiphophorus maculatus86.060.01192
LLPS-Gaa-3172Gasterosteus aculeatus85.580.01199
LLPS-Scm-1134Scophthalmus maximus85.010.01205
LLPS-Asm-2805Astyanax mexicanus84.540.01194
LLPS-Paa-2690Papio anubis84.420.0 946
LLPS-Meg-1591Meleagris gallopavo82.720.0 943
LLPS-Dar-0282Danio rerio79.850.01165
LLPS-Drm-0747Drosophila melanogaster70.922e-175 550
LLPS-Cis-1590Ciona savignyi66.22e-99 313
LLPS-Cae-0902Caenorhabditis elegans51.898e-165 509
LLPS-Coc-1441Corchorus capsularis51.622e-122 379
LLPS-Sot-1931Solanum tuberosum51.126e-124 383
LLPS-Cym-0416Cyanidioschyzon merolae50.456e-127 407
LLPS-Thc-1485Theobroma cacao50.223e-136 427
LLPS-Nia-0760Nicotiana attenuata49.895e-138 422
LLPS-Cii-1907Ciona intestinalis49.650.0 611
LLPS-Hea-0236Helianthus annuus49.245e-136 425
LLPS-Mua-0981Musa acuminata49.153e-133 417
LLPS-Osl-1108Ostreococcus lucimarinus48.985e-132 405
LLPS-Cus-0446Cucumis sativus48.981e-139 434
LLPS-Brr-1195Brassica rapa48.971e-133 419
LLPS-Zem-1575Zea mays48.914e-129 407
LLPS-Brn-2059Brassica napus48.761e-132 408
LLPS-Bro-0758Brassica oleracea48.474e-131 412
LLPS-Tra-1648Triticum aestivum48.378e-129 406
LLPS-Met-2371Medicago truncatula48.355e-136 424
LLPS-Sob-2040Sorghum bicolor48.185e-131 412
LLPS-Art-1190Arabidopsis thaliana48.164e-134 420
LLPS-Dac-1389Daucus carota48.159e-136 423
LLPS-Pot-0507Populus trichocarpa47.963e-135 423
LLPS-Sol-0866Solanum lycopersicum47.841e-136 426
LLPS-Glm-0085Glycine max47.754e-137 428
LLPS-Amt-0885Amborella trichopoda47.732e-132 415
LLPS-Arl-1514Arabidopsis lyrata47.642e-128 405
LLPS-Brd-0091Brachypodium distachyon47.333e-133 418
LLPS-Gor-2504Gossypium raimondii47.188e-133 417
LLPS-Vir-1528Vigna radiata47.136e-136 427
LLPS-Ors-1287Oryza sativa47.038e-132 414
LLPS-Orr-0913Oryza rufipogon47.038e-132 414
LLPS-Ori-0160Oryza indica47.038e-132 414
LLPS-Orni-2307Oryza nivara47.038e-132 414
LLPS-Hov-0201Hordeum vulgare46.942e-129 409
LLPS-Phv-0554Phaseolus vulgaris46.937e-136 424
LLPS-Via-0270Vigna angularis46.935e-136 425
LLPS-Orbr-2291Oryza brachyantha46.833e-131 411
LLPS-Orgl-1689Oryza glumaepatula46.835e-131 412
LLPS-Viv-1420Vitis vinifera46.828e-132 414
LLPS-Org-0999Oryza glaberrima46.634e-130 409
LLPS-Mae-2031Manihot esculenta46.572e-137 428
LLPS-Orm-0495Oryza meridionalis46.495e-132 414
LLPS-Lep-1076Leersia perrieri46.422e-130 410
LLPS-Orp-1240Oryza punctata45.924e-131 412
LLPS-Sem-1020Selaginella moellendorffii45.371e-130 409
LLPS-Sei-1010Setaria italica45.332e-130 410
LLPS-Orb-0141Oryza barthii45.11e-126 401
LLPS-Php-1217Physcomitrella patens44.992e-129 405
LLPS-Chc-0606Chondrus crispus44.853e-122 389
LLPS-Prp-0505Prunus persica44.762e-132 416
LLPS-Chr-0789Chlamydomonas reinhardtii43.314e-100 341
LLPS-Gas-0114Galdieria sulphuraria40.759e-95 314
LLPS-Tru-0777Triticum urartu38.372e-96 324
LLPS-Pug-0774Puccinia graminis36.333e-30 128
LLPS-Scc-0087Schizosaccharomyces cryophilus34.365e-25 115
LLPS-Mel-0704Melampsora laricipopulina33.881e-26 118
LLPS-Nec-0236Neurospora crassa32.381e-25 114
LLPS-Scj-0499Schizosaccharomyces japonicus32.351e-28 127
LLPS-Blg-0151Blumeria graminis31.972e-24 110
LLPS-Lem-0584Leptosphaeria maculans31.279e-25 111
LLPS-Pytr-0035Pyrenophora triticirepentis31.165e-25 112
LLPS-Pyt-0412Pyrenophora teres31.164e-25 112
LLPS-Dos-0453Dothistroma septosporum31.06e-26 115
LLPS-Aso-1022Aspergillus oryzae31.05e-25 112
LLPS-Asf-0776Aspergillus flavus31.05e-25 112
LLPS-Phn-0388Phaeosphaeria nodorum30.914e-25 112
LLPS-Fus-0310Fusarium solani30.743e-24 109
LLPS-Ast-0170Aspergillus terreus30.631e-24 110
LLPS-Zyt-0234Zymoseptoria tritici30.638e-26 115
LLPS-Coo-0525Colletotrichum orbiculare29.644e-25 112
LLPS-Ved-0240Verticillium dahliae29.292e-24 110
LLPS-Cogr-0808Colletotrichum graminicola29.291e-24 111