• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-0141
Lrrc59

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: leucine-rich repeat-containing protein 59
Gene Name: Lrrc59
Ensembl Gene: ENSMAUG00000020384.1
Ensembl Protein: ENSMAUP00000023153.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTKAGNKGGN  LRDKLDGNEL  DLSLSDLNEV  PVKELAALPK  ATVLDLSCNK  LSTLPSDFCG  60
61    LTHLVKLDLS  KNKLQQLPAD  FGRLVNLQHL  DLLNNRLVTL  PVSFAQLKNL  KWLDLKDNPL  120
121   DPVLAKVAGD  CLDEKQCKQC  ANKVLQHMKA  VQADQERERQ  RRLEVEREAE  KKREAKQQAK  180
181   EAKERELRKR  EKAEEKERRR  KEYDAQKASK  REQEKKPKKE  TNQAPKPKSG  SRPRKPPPRK  240
241   HTRSWVVLKV  LLLLLLICVA  GGLVACRMTG  LQQQPLCSRV  NTIYDNAVQG  LRHHEILQWV  300
301   LQTDSQQ  307
Nucleotide CDS Sequence (FASTA)
1     ATGACCAAGG  CCGGTAACAA  GGGCGGGAAC  CTCCGCGACA  AGCTGGACGG  CAATGAGCTG  60
61    GACCTGAGTC  TCAGCGACCT  GAATGAGGTC  CCCGTCAAGG  AGCTGGCTGC  ACTCCCAAAG  120
121   GCCACCGTAT  TGGATCTGTC  CTGCAATAAA  CTGAGTACTC  TTCCGTCGGA  TTTCTGTGGC  180
181   CTCACACACC  TGGTGAAGTT  GGACCTGAGC  AAGAACAAGC  TGCAGCAGCT  GCCTGCAGAC  240
241   TTTGGCCGCC  TGGTCAACCT  TCAGCATTTG  GATCTCCTCA  ACAACAGGCT  GGTCACCCTG  300
301   CCTGTCAGCT  TTGCTCAGCT  CAAGAATCTG  AAGTGGCTGG  ATCTGAAAGA  CAATCCTCTG  360
361   GATCCTGTCC  TGGCCAAGGT  GGCAGGAGAT  TGCTTGGATG  AGAAGCAATG  TAAGCAGTGT  420
421   GCAAACAAGG  TGTTACAGCA  CATGAAGGCG  GTGCAGGCGG  ATCAGGAGCG  AGAGCGGCAG  480
481   CGCCGGCTGG  AAGTGGAGCG  AGAGGCAGAG  AAGAAGCGAG  AGGCCAAGCA  GCAAGCTAAG  540
541   GAAGCAAAGG  AACGCGAGCT  GCGCAAGCGG  GAGAAGGCAG  AGGAGAAGGA  GCGCCGGCGA  600
601   AAGGAGTACG  ATGCCCAGAA  AGCTTCCAAG  CGAGAGCAGG  AGAAGAAGCC  CAAGAAGGAA  660
661   ACAAATCAGG  CCCCAAAACC  TAAGTCTGGC  TCTCGTCCTC  GCAAGCCACC  ACCCCGAAAA  720
721   CATACTCGCT  CCTGGGTCGT  GCTGAAGGTG  CTGCTGCTGC  TGCTGCTGAT  CTGTGTGGCA  780
781   GGAGGGCTAG  TTGCATGCCG  GATGACAGGG  CTGCAACAGC  AGCCCCTCTG  CAGTAGGGTG  840
841   AACACCATCT  ACGACAATGC  CGTCCAGGGC  CTGCGTCATC  ACGAGATCCT  CCAGTGGGTC  900
901   CTCCAGACCG  ACTCCCAGCA  GTGA  924

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-2959Fukomys damarensis97.221e-76 239
LLPS-Mum-4871Mus musculus96.746e-125 367
LLPS-Ran-1341Rattus norvegicus96.094e-124 365
LLPS-Ict-2263Ictidomys tridecemlineatus94.791e-122 361
LLPS-Orc-2953Oryctolagus cuniculus94.469e-122 358
LLPS-Man-2206Macaca nemestrina94.143e-122 360
LLPS-Mam-1762Macaca mulatta94.143e-122 360
LLPS-Caj-1998Callithrix jacchus94.143e-121 357
LLPS-Maf-4225Macaca fascicularis94.143e-122 360
LLPS-Chs-3650Chlorocebus sabaeus94.143e-122 360
LLPS-Aon-1950Aotus nancymaae94.143e-121 357
LLPS-Paa-0613Papio anubis94.143e-122 360
LLPS-Mal-3120Mandrillus leucophaeus94.143e-122 360
LLPS-Dio-0481Dipodomys ordii94.145e-113 336
LLPS-Rhb-0341Rhinopithecus bieti93.812e-122 360
LLPS-Hos-4212Homo sapiens93.811e-121 358
LLPS-Pap-4704Pan paniscus93.811e-121 358
LLPS-Pat-2725Pan troglodytes93.811e-121 358
LLPS-Poa-1781Pongo abelii93.811e-119 353
LLPS-Gog-4530Gorilla gorilla93.811e-121 358
LLPS-Cea-2824Cercocebus atys93.818e-122 359
LLPS-Nol-3263Nomascus leucogenys93.496e-121 357
LLPS-Cas-0733Carlito syrichta92.187e-119 351
LLPS-Eqc-3235Equus caballus91.862e-118 350
LLPS-Bot-0210Bos taurus91.534e-119 352
LLPS-Loa-1581Loxodonta africana91.213e-116 345
LLPS-Ova-0371Ovis aries91.216e-119 352
LLPS-Ere-0339Erinaceus europaeus90.882e-115 342
LLPS-Sus-3986Sus scrofa90.553e-116 345
LLPS-Fec-4059Felis catus90.231e-115 343
LLPS-Cap-4460Cavia porcellus89.92e-117 347
LLPS-Mup-4390Mustela putorius furo89.581e-114 340
LLPS-Myl-2363Myotis lucifugus89.253e-105 317
LLPS-Aim-0884Ailuropoda melanoleuca89.254e-112 334
LLPS-Tut-0452Tursiops truncatus89.252e-116 345
LLPS-Caf-0880Canis familiaris89.221e-110 331
LLPS-Lac-3420Latimeria chalumnae83.895e-64 211
LLPS-Mod-2330Monodelphis domestica79.552e-88 274
LLPS-Sah-1450Sarcophilus harrisii79.22e-66 216
LLPS-Urm-3874Ursus maritimus78.833e-102 308
LLPS-Xet-3728Xenopus tropicalis75.843e-62 206
LLPS-Asm-3937Astyanax mexicanus75.526e-56 191
LLPS-Otg-0127Otolemur garnettii74.134e-110 330
LLPS-Orl-2935Oryzias latipes73.156e-54 185
LLPS-Pof-3435Poecilia formosa72.861e-50 178
LLPS-Dar-3618Danio rerio72.69e-53 181
LLPS-Orn-1369Oreochromis niloticus72.141e-52 181
LLPS-Xim-2394Xiphophorus maculatus72.141e-50 176
LLPS-Icp-1322Ictalurus punctatus70.471e-51 179
LLPS-Tag-2711Taeniopygia guttata70.457e-84 262
LLPS-Pes-2592Pelodiscus sinensis70.136e-85 265
LLPS-Scm-3760Scophthalmus maximus70.05e-49 172
LLPS-Gaa-4013Gasterosteus aculeatus70.06e-49 171
LLPS-Gaga-1981Gallus gallus69.817e-85 266
LLPS-Tar-3935Takifugu rubripes68.973e-49 172
LLPS-Ten-3612Tetraodon nigroviridis68.575e-47 166
LLPS-Anc-0772Anolis carolinensis67.862e-82 258
LLPS-Leo-3174Lepisosteus oculatus59.872e-67 220
LLPS-Fia-1690Ficedula albicollis59.536e-77 245
LLPS-Cii-0370Ciona intestinalis58.431e-1784.3
LLPS-Cis-1689Ciona savignyi58.162e-37 139
LLPS-Meg-1735Meleagris gallopavo57.672e-57 193
LLPS-Scf-3099Scleropages formosus57.621e-59 199
LLPS-Drm-2180Drosophila melanogaster50.01e-26 111
LLPS-Sol-1187Solanum lycopersicum47.626e-0651.6
LLPS-Cae-0990Caenorhabditis elegans47.416e-2196.3
LLPS-Anp-1269Anas platyrhynchos47.221e-0860.1
LLPS-Ora-0935Ornithorhynchus anatinus47.229e-0960.5
LLPS-Abg-0847Absidia glauca46.677e-0754.7
LLPS-Pot-2525Populus trichocarpa46.343e-1064.7
LLPS-Coc-1433Corchorus capsularis46.051e-0860.1
LLPS-Amt-1011Amborella trichopoda45.836e-0960.8
LLPS-Thc-0765Theobroma cacao44.446e-0857.8
LLPS-Art-2135Arabidopsis thaliana43.11e-0653.5
LLPS-Sei-2345Setaria italica42.478e-0857.4
LLPS-Nia-2095Nicotiana attenuata42.171e-0860.1
LLPS-Phv-2207Phaseolus vulgaris41.864e-0858.5
LLPS-Brn-2670Brassica napus41.674e-0858.5
LLPS-Mua-2359Musa acuminata41.11e-0653.9
LLPS-Prp-0663Prunus persica34.384e-0858.5