LLPS-Man-4857
PCSK6
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Uncharacterized protein |
| Gene Name: | PCSK6 |
| Ensembl Gene: | ENSMNEG00000002880.1 |
| Ensembl Protein: | ENSMNEP00000000754.1 |
| Organism: | Macaca nemestrina |
| Taxa ID: | 9545 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| P-body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMNET00000004015.1 | ENSMNEP00000000754.1 |
| Ensembl | ENSMNET00000004080.1 | ENSMNEP00000000767.1 |
| Ensembl | ENSMNET00000004157.1 | ENSMNEP00000000793.1 |
| Ensembl | ENSMNET00000004169.1 | ENSMNEP00000000796.1 |
| Ensembl | ENSMNET00000004141.1 | ENSMNEP00000000780.1 |
| UniProt | A0A2K6ANP9, A0A2K6ANP9_MACNE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPRARCLRRP AAPRPPPPPP PPRARERGVP SAWLRPLAPR PWRWLLLLAL PAACSAPPPR 60 61 PVYTNHWAVQ VLGGPAEADR VAAAHGYLNL GQIGNLEDYY HFYHSKTFKR STLSSRGPHT 120 121 FLRMDPQVKW LQQQEVKRRV KRQVRSDPQA LYFNDPIWSN MWYLHCGDKN SRCRSEMNVQ 180 181 AAWKRGYTGK NVVVTILDDG IERNHPDLAP NYDSYASYDV NGNDYDPSPR YDASNENKHG 240 241 TRCAGEVAAS ANNSYCIVGI AYNAKIGGIR MLDGDVTDVV EAKSLGIRPN YIDIYSASWG 300 301 PDDDGKTVDG PGRLAKQAFE YGIKKGRQGL GSIFVWASGN GGREGDYCSC DGYTNSIYTI 360 361 SVSSATENGY KPWYLEECAS TLATTYSSGA FYERKIVTTD LRQRCTDGHT GTSVSAPMVA 420 421 GIIALALEAN GQLTWRDVQH LLVKTSRPAH LKASDWKVNG AGHKVSHFYG FGLVDAEALV 480 481 VEAKKWTAVP SQHMCVAASD KRPRSIPLVQ VLRTTALTSA CAEHSDQRVV YLEHVVVRIS 540 541 ISHPRRGDLQ IYLISPSGTK SQLLAKRLLD LSNEGFTNWE FMTVHCWGEK AEGQWTLEIQ 600 601 DLPSQVRNPE KQGKLKEWSL ILYGTAEHPY HTFSAHQSRS RMLELTAPEL EPPKAALSPS 660 661 QMEVPEDEED YTAHSTPGSA NILQTSVCHP ECGDKGCDGP NADQCLNCIH FSLGSVKTSR 720 721 KCVSVCPLGY FGDTAARRCR RCHKGCETCS GRGATQCLSC RRGFYHHQEM NTCVTLCPVG 780 781 FYADESQKNC LKCHPSCKKC VDEPERCTVC KEGFSLARGS CIPDCEPGTY FDSELIRCGE 840 841 CHHTCGTCVG PGREECIHCA KNFHFQDWKC VPACGEGFYP EEMPGLPHKV CRRYGLPGRE 900 901 RQAAVSSKGV TGGQSLAASS PGAGGGREPI YRAGWATG 938 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCTCGCG CGCGCTGCCT GCGCCGGCCC GCCGCGCCCC GGCCGCCGCC GCCACCGCCG 60 61 CCGCCGCGGG CGCGGGAACG CGGGGTGCCG TCGGCCTGGC TCCGGCCGCT CGCGCCGCGT 120 121 CCCTGGCGCT GGCTGCTGCT GCTGGCGCTG CCTGCCGCCT GCTCCGCGCC CCCGCCGCGC 180 181 CCCGTCTACA CCAACCACTG GGCAGTGCAA GTGCTGGGTG GCCCGGCCGA AGCGGACCGC 240 241 GTGGCCGCGG CGCACGGCTA CCTCAACTTG GGCCAGATTG GAAACCTGGA AGATTACTAC 300 301 CATTTTTATC ACAGCAAAAC CTTTAAAAGA TCGACCTTGA GTAGCAGAGG CCCTCACACC 360 361 TTCCTCAGAA TGGACCCCCA GGTGAAATGG CTTCAGCAAC AGGAAGTGAA ACGAAGGGTG 420 421 AAGAGACAGG TGCGAAGTGA CCCACAGGCC CTTTACTTCA ATGACCCCAT TTGGTCCAAC 480 481 ATGTGGTACC TGCATTGTGG CGACAAGAAC AGTCGCTGCC GGTCAGAAAT GAATGTCCAG 540 541 GCAGCGTGGA AGAGGGGCTA CACAGGAAAA AATGTGGTGG TCACCATCCT CGATGATGGC 600 601 ATAGAGAGGA ATCACCCTGA CCTGGCCCCA AATTATGATT CCTACGCCAG CTATGATGTC 660 661 AACGGCAATG ATTATGACCC ATCTCCACGA TACGATGCCA GCAATGAAAA TAAACACGGT 720 721 ACTCGTTGTG CGGGAGAAGT TGCTGCTTCA GCAAACAACT CTTACTGCAT CGTGGGCATA 780 781 GCATACAATG CCAAAATAGG AGGCATCCGC ATGCTGGATG GCGACGTCAC AGATGTGGTC 840 841 GAGGCAAAGT CGCTGGGCAT CAGACCCAAC TACATCGACA TTTACAGTGC CAGCTGGGGG 900 901 CCAGACGACG ATGGGAAGAC GGTGGATGGG CCCGGCCGAC TGGCTAAGCA GGCTTTCGAG 960 961 TATGGCATTA AAAAGGGCCG GCAGGGCCTG GGCTCCATTT TCGTCTGGGC ATCTGGGAAC 1020 1021 GGTGGGAGAG AGGGAGACTA CTGCTCGTGT GATGGCTACA CCAACAGCAT CTACACCATC 1080 1081 TCCGTCAGCA GCGCCACTGA GAATGGCTAC AAGCCCTGGT ACCTGGAAGA GTGCGCCTCC 1140 1141 ACCCTGGCGA CCACCTACAG CAGCGGAGCC TTTTATGAGC GAAAAATCGT CACCACCGAT 1200 1201 CTGCGTCAGC GCTGTACCGA TGGCCACACC GGGACCTCAG TCTCTGCCCC CATGGTGGCT 1260 1261 GGCATCATCG CCTTGGCTCT AGAAGCAAAC GGCCAGTTAA CCTGGAGGGA CGTCCAGCAC 1320 1321 CTGCTAGTGA AGACATCCCG GCCGGCCCAC CTGAAAGCGA GTGACTGGAA AGTGAACGGC 1380 1381 GCGGGTCATA AAGTTAGCCA TTTCTATGGA TTTGGTTTGG TGGACGCAGA AGCTCTCGTT 1440 1441 GTGGAGGCAA AGAAGTGGAC AGCGGTGCCA TCGCAGCACA TGTGTGTGGC CGCCTCGGAC 1500 1501 AAGAGACCCA GGAGCATCCC CTTAGTGCAG GTGCTGCGGA CTACGGCCCT GACCAGTGCC 1560 1561 TGCGCGGAGC ACTCGGACCA GCGCGTGGTC TACTTGGAGC ACGTGGTGGT TCGCATCTCC 1620 1621 ATCTCGCACC CACGCCGAGG AGACCTCCAG ATCTACCTGA TTTCTCCCTC GGGAACCAAG 1680 1681 TCTCAACTTT TGGCAAAGAG ATTGCTGGAT CTTTCCAATG AAGGGTTTAC AAACTGGGAA 1740 1741 TTCATGACTG TCCACTGTTG GGGAGAAAAG GCTGAAGGGC AGTGGACCTT GGAAATCCAA 1800 1801 GACCTGCCAT CCCAGGTCCG CAACCCGGAG AAGCAAGGGA AGTTGAAAGA ATGGAGCCTC 1860 1861 ATATTGTATG GCACAGCGGA GCACCCGTAC CACACCTTCA GTGCCCATCA GTCCCGCTCA 1920 1921 CGGATGCTGG AGCTCACGGC CCCAGAGCTG GAGCCACCCA AGGCCGCCCT GTCACCCTCC 1980 1981 CAGATGGAAG TTCCTGAAGA TGAGGAAGAT TACACAGCTC ATTCCACCCC AGGCTCTGCT 2040 2041 AATATTTTAC AGACCAGTGT GTGCCATCCG GAGTGTGGTG ACAAAGGCTG TGATGGCCCC 2100 2101 AATGCAGACC AGTGCTTGAA CTGCATCCAC TTCAGCCTGG GGAGCGTTAA GACCAGCAGG 2160 2161 AAGTGTGTGA GCGTGTGCCC CTTGGGGTAC TTTGGGGACA CAGCAGCAAG ACGCTGTCGC 2220 2221 CGGTGCCACA AGGGGTGTGA GACCTGCTCC GGCAGGGGTG CGACACAGTG CCTGTCTTGC 2280 2281 CGCCGCGGGT TCTATCACCA CCAGGAGATG AACACCTGTG TGACCCTCTG TCCTGTAGGA 2340 2341 TTTTATGCTG ATGAAAGTCA GAAAAATTGC CTTAAATGCC ACCCAAGCTG TAAAAAGTGC 2400 2401 GTGGATGAAC CCGAGAGATG CACTGTCTGT AAAGAAGGAT TCAGCCTTGC ACGGGGCAGC 2460 2461 TGCATTCCTG ACTGCGAGCC AGGCACCTAC TTTGACTCAG AGCTGATCAG ATGTGGGGAA 2520 2521 TGCCATCACA CCTGCGGAAC CTGCGTGGGG CCAGGCAGAG AAGAGTGCAT TCACTGTGCA 2580 2581 AAAAACTTCC ACTTCCAAGA CTGGAAGTGT GTGCCAGCCT GTGGTGAGGG GTTCTACCCA 2640 2641 GAGGAGATGC CGGGCTTGCC CCACAAAGTG TGTCGAAGGT ACGGTCTTCC TGGCAGGGAA 2700 2701 CGGCAGGCAG CTGTGTCCAG CAAAGGAGTG ACTGGAGGGC AGAGTCTGGC AGCATCTTCC 2760 2761 CCAGGGGCTG GGGGAGGGCG TGAGCCCATT TACAGAGCTG GTTGGGCAAC AGGATAG 2817 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Paa-2262 | Papio anubis | 99.76 | 0.0 | 1737 |
| LLPS-Cea-1574 | Cercocebus atys | 99.76 | 0.0 | 1703 |
| LLPS-Mal-2839 | Mandrillus leucophaeus | 99.63 | 0.0 | 1642 |
| LLPS-Chs-2332 | Chlorocebus sabaeus | 99.48 | 0.0 | 1575 |
| LLPS-Rhb-1984 | Rhinopithecus bieti | 98.92 | 0.0 | 1687 |
| LLPS-Poa-0137 | Pongo abelii | 98.64 | 0.0 | 1637 |
| LLPS-Nol-1692 | Nomascus leucogenys | 98.5 | 0.0 | 1629 |
| LLPS-Hos-1510 | Homo sapiens | 98.35 | 0.0 | 1714 |
| LLPS-Pat-2587 | Pan troglodytes | 98.2 | 0.0 | 1683 |
| LLPS-Mam-1313 | Macaca mulatta | 98.08 | 0.0 | 1667 |
| LLPS-Gog-3123 | Gorilla gorilla | 97.92 | 0.0 | 1647 |
| LLPS-Maf-4488 | Macaca fascicularis | 96.66 | 0.0 | 1649 |
| LLPS-Caj-4115 | Callithrix jacchus | 96.63 | 0.0 | 1661 |
| LLPS-Aon-1929 | Aotus nancymaae | 96.39 | 0.0 | 1654 |
| LLPS-Pap-2163 | Pan paniscus | 95.98 | 0.0 | 1658 |
| LLPS-Orc-2049 | Oryctolagus cuniculus | 94.88 | 0.0 | 1575 |
| LLPS-Sus-2426 | Sus scrofa | 94.59 | 0.0 | 1611 |
| LLPS-Fec-3647 | Felis catus | 93.87 | 0.0 | 1582 |
| LLPS-Mup-3212 | Mustela putorius furo | 93.77 | 0.0 | 1481 |
| LLPS-Aim-3994 | Ailuropoda melanoleuca | 93.64 | 0.0 | 1540 |
| LLPS-Caf-1365 | Canis familiaris | 93.52 | 0.0 | 1536 |
| LLPS-Ict-3273 | Ictidomys tridecemlineatus | 93.51 | 0.0 | 1594 |
| LLPS-Eqc-0072 | Equus caballus | 92.79 | 0.0 | 1563 |
| LLPS-Otg-3838 | Otolemur garnettii | 92.41 | 0.0 | 1545 |
| LLPS-Cap-3623 | Cavia porcellus | 92.26 | 0.0 | 1539 |
| LLPS-Mum-4597 | Mus musculus | 92.07 | 0.0 | 1590 |
| LLPS-Fud-2303 | Fukomys damarensis | 92.01 | 0.0 | 1535 |
| LLPS-Ran-1417 | Rattus norvegicus | 91.11 | 0.0 | 1542 |
| LLPS-Bot-2175 | Bos taurus | 90.57 | 0.0 | 1512 |
| LLPS-Ova-2732 | Ovis aries | 90.14 | 0.0 | 1510 |
| LLPS-Urm-2596 | Ursus maritimus | 90.1 | 0.0 | 1502 |
| LLPS-Loa-4405 | Loxodonta africana | 89.78 | 0.0 | 1435 |
| LLPS-Sah-2543 | Sarcophilus harrisii | 86.42 | 0.0 | 1502 |
| LLPS-Mod-3755 | Monodelphis domestica | 86.18 | 0.0 | 1500 |
| LLPS-Dio-1046 | Dipodomys ordii | 85.98 | 0.0 | 1405 |
| LLPS-Fia-1684 | Ficedula albicollis | 75.49 | 0.0 | 1163 |
| LLPS-Tag-3145 | Taeniopygia guttata | 75.45 | 0.0 | 1248 |
| LLPS-Gaga-1393 | Gallus gallus | 74.52 | 0.0 | 1253 |
| LLPS-Pes-3347 | Pelodiscus sinensis | 73.57 | 0.0 | 1214 |
| LLPS-Meg-2780 | Meleagris gallopavo | 73.57 | 0.0 | 1203 |
| LLPS-Leo-0946 | Lepisosteus oculatus | 70.13 | 0.0 | 1192 |
| LLPS-Scf-0933 | Scleropages formosus | 70.07 | 0.0 | 1191 |
| LLPS-Asm-3660 | Astyanax mexicanus | 69.27 | 0.0 | 1164 |
| LLPS-Ora-3217 | Ornithorhynchus anatinus | 69.19 | 0.0 | 1071 |
| LLPS-Lac-3456 | Latimeria chalumnae | 69.1 | 0.0 | 1059 |
| LLPS-Xet-2177 | Xenopus tropicalis | 68.87 | 0.0 | 1175 |
| LLPS-Icp-0667 | Ictalurus punctatus | 68.79 | 0.0 | 1170 |
| LLPS-Anp-3165 | Anas platyrhynchos | 66.04 | 0.0 | 1049 |
| LLPS-Scm-0552 | Scophthalmus maximus | 65.5 | 0.0 | 1085 |
| LLPS-Gaa-3652 | Gasterosteus aculeatus | 65.26 | 0.0 | 1093 |
| LLPS-Orl-3794 | Oryzias latipes | 61.97 | 0.0 | 1050 |
| LLPS-Anc-3591 | Anolis carolinensis | 36.36 | 3e-09 | 65.5 |
| LLPS-Orn-3573 | Oreochromis niloticus | 35.61 | 2e-08 | 62.8 |
| LLPS-Pof-3758 | Poecilia formosa | 34.85 | 2e-07 | 59.7 |
| LLPS-Dar-3309 | Danio rerio | 34.81 | 2e-08 | 63.2 |
| LLPS-Xim-2436 | Xiphophorus maculatus | 34.09 | 4e-07 | 58.5 |
| LLPS-Tar-1638 | Takifugu rubripes | 34.09 | 3e-06 | 55.8 |
| LLPS-Cas-3976 | Carlito syrichta | 32.85 | 1e-06 | 57.0 |
| LLPS-Ten-3240 | Tetraodon nigroviridis | 32.58 | 1e-06 | 57.0 |
| LLPS-Mea-0377 | Mesocricetus auratus | 31.39 | 5e-07 | 58.2 |
| LLPS-Drm-1945 | Drosophila melanogaster | 30.05 | 3e-15 | 85.1 |
| LLPS-Cae-2063 | Caenorhabditis elegans | 29.29 | 5e-10 | 68.2 |