LLPS-Man-2361
FGFR1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Fibroblast growth factor receptor |
| Gene Name: | FGFR1 |
| Ensembl Gene: | ENSMNEG00000033546.1 |
| Ensembl Protein: | ENSMNEP00000020146.1 |
| Organism: | Macaca nemestrina |
| Taxa ID: | 9545 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus, Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMNET00000044391.1 | ENSMNEP00000020146.1 |
| Ensembl | ENSMNET00000044396.1 | ENSMNEP00000020151.1 |
| Ensembl | ENSMNET00000044321.1 | ENSMNEP00000020076.1 |
| Ensembl | ENSMNET00000044382.1 | ENSMNEP00000020137.1 |
| Ensembl | ENSMNET00000044407.1 | ENSMNEP00000020162.1 |
| Ensembl | ENSMNET00000044316.1 | ENSMNEP00000020071.1 |
| Ensembl | ENSMNET00000044414.1 | ENSMNEP00000020169.1 |
| Ensembl | ENSMNET00000044417.1 | ENSMNEP00000020172.1 |
| Ensembl | ENSMNET00000044355.1 | ENSMNEP00000020110.1 |
| UniProt | A0A2K6C8X2, A0A2K6C8X2_MACNE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEAGVSLKRR IELKVEYPWR CGALSPTSKC RTGMWSWKCL LFWAVLVTAT LCTARPSPTL 60 61 PEQAQPWGAP VEVESFLVHP GDLLQLRCRL RDDVQSINWL RDGVQLAESN RTRITGEEVE 120 121 VQDSVPADSG LYACVTSSPS GSDTTYFSVN VSDALPSSED DDDDDDSSSE EKETDNTKPN 180 181 PVAPYWTSPE KMEKKLHAVP AAKTVKFKCP SSGTPNPTLR WLKNGKEFKP DHRIGGYKVR 240 241 YATWSIIMDS VVPSDKGNYT CIVENEYGSI NHTYQLDVVE RSPHRPILQA GLPANKTVAL 300 301 GSNVEFMCKV YSDPQPHIQW LKHIEVNGSK TGPDNLPYVQ ILKTAGVNTT DKEMEVLHLR 360 361 NVSFEDAGEY TCLAGNSIGL SHHSAWLTVL EALEERPVVM TSPLYLEIII YCTGAFLISC 420 421 MVGSVIVYKM KSGTKKSDFH SQMAVHKLAK SIPLRRQVTV SADSSASMNS GVLLVRPSRL 480 481 SSSGTPMLAG VSEYELPEDP RWELPRDRLV LGKPLGEGCF GQVVLAEAIG LDKDKPNRVT 540 541 KVAVKMLKSD ATEKDLSDLI SEMEMMKMIG KHKNIINLLG ACTQDGPLYV IVEYASKGNL 600 601 REYLQARRPP GLEYCYNPSH NPEEQLSSKD LVSCAYQVAR GMEYLASKKC IHRDLAARNV 660 661 LVTEDNVMKI ADFGLARDIH HIDYYKKTTN GRLPVKWMAP EALFDRIYTH QSDVWSFGVL 720 721 LWEIFTLGGS PYPGVPVEEL FKLLKEGHRM DKPSNCTNEL YMMMRDCWHA VPSQRPTFKQ 780 781 LVEDLDRIVA LTSNQEYLDL SMPLDQYSPS FPDTRSSTCS SGEDSVFSHE PLPEEPCLPR 840 841 HPAQLANGGL KRR 853 |
| Nucleotide CDS Sequence (FASTA) |
1 GTGGTAGCTG TGACCCGGGA GACGCTTCCG CGCTCTGGCC GGGTCCTGCC AGCCGAAGCC 60 61 CAGCCCTGGG GAGCCCCTGT GGAAGTGGAG TCCTTCCTGG TCCACCCCGG TGACCTGCTG 120 121 CAGCTTCGCT GTCGGCTGCG GGACGATGTG CAGAGCATCA ACTGGCTGCG GGACGGGGTG 180 181 CAGCTGGCAG AAAGCAACCG CACCCGCATC ACAGGGGAGG AGGTGGAGGT GCAGGACTCC 240 241 GTGCCCGCGG ACTCCGGCCT CTATGCTTGC GTAACCAGCA GCCCCTCGGG CAGCGACACC 300 301 ACCTACTTCT CCGTCAATGT TTCAGATGCT CTCCCCTCCT CAGAGGATGA TGATGATGAT 360 361 GATGACTCCT CTTCAGAGGA GAAAGAGACA GATAACACCA AACCAAACCG TATGCCCGTA 420 421 GCTCCATATT GGACATCCCC AGAAAAGATG GAAAAGAAAT TGCATGCGGT GCCAGCTGCC 480 481 AAGACAGTGA AGTTCAAATG CCCTTCCAGT GGGACCCCAA ACCCCACACT GCGCTGGTTG 540 541 AAAAATGGCA AAGAATTCAA ACCCGACCAC AGGATTGGAG GCTACAAGGT CCGTTATGCC 600 601 ACCTGGAGCA TCATAATGGA CTCCGTGGTG CCCTCTGACA AGGGCAACTA CACCTGCATT 660 661 GTGGAGAATG AGTATGGCAG CATCAACCAC ACCTACCAGC TGGATGTCGT GGAGCGGTCC 720 721 CCTCACCGGC CCATCCTGCA AGCAGGGTTG CCCGCCAACA AGACAGTGGC CCTGGGTAGC 780 781 AACGTGGAGT TCATGTGTAA GGTGTACAGT GACCCACAGC CGCATATCCA GTGGCTAAAG 840 841 CACATCGAGG TGAACGGGAG CAAGACTGGT CCAGACAACC TGCCTTATGT CCAGATCTTG 900 901 AAGACTGCTG GAGTTAATAC CACCGACAAA GAGATGGAGG TGCTTCACTT AAGAAATGTC 960 961 TCCTTTGAGG ACGCAGGGGA GTATACGTGC TTGGCGGGTA ACTCTATCGG ACTCTCCCAT 1020 1021 CACTCTGCAT GGTTGACCGT TCTGGAAGCT CTGGAAGAGA GGCCGGTGGT GATGACCTCG 1080 1081 CCCCTGTACC TGGAGATCAT CATCTATTGC ACAGGGGCCT TCCTCATCTC CTGCATGGTA 1140 1141 GGGTCGGTCA TCGTCTACAA GATGAAGAGT GGCACCAAGA AGAGCGACTT CCACAGCCAG 1200 1201 ATGGCTGTGC ACAAGCTGGC CAAGAGCATC CCTCTGCGCA GACAGGTGTC TGCTGACTCC 1260 1261 AGTGCGTCCA TGAACTCTGG GGTTCTTCTG GTTCGGCCAT CACGGCTCTC CTCCAGTGGG 1320 1321 ACTCCCATGC TAGCAGGGGT CTCCGAGTAT GAGCTTCCTG AAGACCCTCG CTGGGAGCTG 1380 1381 CCTCGGGACA GACTGGTCTT AGGCAAACCC CTGGGAGAGG GCTGCTTTGG GCAGGTGGTG 1440 1441 TTGGCAGAGG CCATCGGGTT GGACAAGGAC AAACCCAACC GTGTGACCAA AGTGGCTGTG 1500 1501 AAGATGTTGA AGTCGGACGC AACAGAGAAA GACTTGTCAG ACCTGATCTC AGAAATGGAG 1560 1561 ATGATGAAGA TGATCGGGAA GCATAAGAAT ATCATCAACC TGCTGGGGGC CTGCACGCAG 1620 1621 GACGGTCCCT TGTATGTCAT CGTGGAGTAT GCCTCCAAGG GCAACCTGCG GGAGTACCTG 1680 1681 CAGGCCCGGA GGCCCCCGGG GCTGGAATAC TGCTACAACC CCAGCCACAA CCCAGAGGAG 1740 1741 CAGCTCTCCT CCAAGGACCT GGTGTCCTGC GCCTATCAGG TGGCCCGAGG CATGGAGTAT 1800 1801 CTGGCCTCCA AGAAGTGCAT ACACCGAGAC CTGGCCGCCA GGAATGTCCT GGTGACAGAG 1860 1861 GACAATGTGA TGAAGATAGC AGACTTTGGC CTCGCACGGG ACATTCACCA CATCGACTAC 1920 1921 TATAAAAAGA CAACCAACGG TCGACTGCCT GTGAAGTGGA TGGCGCCCGA GGCATTGTTT 1980 1981 GACCGGATCT ACACCCACCA GAGTGATGTG TGGTCTTTCG GGGTGCTTCT GTGGGAGATC 2040 2041 TTCACTCTGG GCGGCTCCCC ATACCCTGGT GTGCCTGTGG AGGAGCTTTT CAAGCTGCTG 2100 2101 AAGGAGGGTC ACCGCATGGA CAAGCCCAGT AACTGCACCA ACGAGCTGTA CATGATGATG 2160 2161 CGGGACTGCT GGCATGCAGT GCCCTCACAG AGACCCACCT TCAAGCAGCT GGTGGAAGAC 2220 2221 CTGGACCGCA TCGTGGCCTT GACCTCCAAC CAGGAGTACC TGGACCTGTC CATGCCCCTG 2280 2281 GACCAGTACT CCCCGAGCTT TCCCGACACC CGGAGCTCTA CATGCTCCTC AGGGGAGGAT 2340 2341 TCCGTCTTCT CTCATGAGCC GCTGCCCGAG GAGCCCTGCC TGCCCCGACA CCCAGCCCAG 2400 2401 CTTGCCAATG GCGGACTCAA ACGCCGCTGA 2430 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Chs-3155 | Chlorocebus sabaeus | 99.74 | 0.0 | 1477 |
| LLPS-Mal-2843 | Mandrillus leucophaeus | 99.53 | 0.0 | 1667 |
| LLPS-Hos-2506 | Homo sapiens | 99.41 | 0.0 | 1662 |
| LLPS-Paa-2376 | Papio anubis | 99.3 | 0.0 | 1662 |
| LLPS-Cea-0688 | Cercocebus atys | 99.27 | 0.0 | 1587 |
| LLPS-Maf-1015 | Macaca fascicularis | 99.27 | 0.0 | 1587 |
| LLPS-Sus-0518 | Sus scrofa | 99.15 | 0.0 | 942 |
| LLPS-Gog-2843 | Gorilla gorilla | 99.15 | 0.0 | 1585 |
| LLPS-Pat-3980 | Pan troglodytes | 99.06 | 0.0 | 1657 |
| LLPS-Ran-3943 | Rattus norvegicus | 99.0 | 0.0 | 1370 |
| LLPS-Pap-1832 | Pan paniscus | 98.87 | 0.0 | 1531 |
| LLPS-Eqc-3538 | Equus caballus | 98.71 | 0.0 | 1650 |
| LLPS-Caf-0553 | Canis familiaris | 98.66 | 0.0 | 1585 |
| LLPS-Aim-3848 | Ailuropoda melanoleuca | 98.66 | 0.0 | 1583 |
| LLPS-Ict-3491 | Ictidomys tridecemlineatus | 98.54 | 0.0 | 1584 |
| LLPS-Cap-4703 | Cavia porcellus | 98.42 | 0.0 | 1578 |
| LLPS-Fud-1664 | Fukomys damarensis | 98.05 | 0.0 | 1570 |
| LLPS-Mup-0209 | Mustela putorius furo | 98.0 | 0.0 | 1634 |
| LLPS-Loa-2316 | Loxodonta africana | 97.95 | 0.0 | 1588 |
| LLPS-Rhb-1423 | Rhinopithecus bieti | 97.95 | 0.0 | 1580 |
| LLPS-Bot-2287 | Bos taurus | 97.64 | 0.0 | 1621 |
| LLPS-Anp-0424 | Anas platyrhynchos | 97.53 | 2e-44 | 175 |
| LLPS-Caj-1584 | Callithrix jacchus | 97.47 | 0.0 | 1570 |
| LLPS-Otg-0754 | Otolemur garnettii | 97.35 | 0.0 | 1498 |
| LLPS-Urm-3318 | Ursus maritimus | 96.95 | 0.0 | 1266 |
| LLPS-Mum-3815 | Mus musculus | 96.76 | 0.0 | 1572 |
| LLPS-Mam-3166 | Macaca mulatta | 96.44 | 0.0 | 1459 |
| LLPS-Sah-1511 | Sarcophilus harrisii | 95.12 | 0.0 | 1501 |
| LLPS-Mea-3827 | Mesocricetus auratus | 93.82 | 0.0 | 1493 |
| LLPS-Meg-0811 | Meleagris gallopavo | 93.26 | 3e-173 | 528 |
| LLPS-Gaga-2822 | Gallus gallus | 91.46 | 0.0 | 1448 |
| LLPS-Mod-2903 | Monodelphis domestica | 90.88 | 0.0 | 1253 |
| LLPS-Fia-0609 | Ficedula albicollis | 89.88 | 0.0 | 1413 |
| LLPS-Tag-2467 | Taeniopygia guttata | 87.74 | 0.0 | 1356 |
| LLPS-Pes-3793 | Pelodiscus sinensis | 82.57 | 0.0 | 1288 |
| LLPS-Anc-1677 | Anolis carolinensis | 81.87 | 0.0 | 1276 |
| LLPS-Asm-2002 | Astyanax mexicanus | 79.7 | 0.0 | 1124 |
| LLPS-Lac-3542 | Latimeria chalumnae | 79.19 | 0.0 | 1202 |
| LLPS-Xet-3913 | Xenopus tropicalis | 79.05 | 0.0 | 1299 |
| LLPS-Poa-4051 | Pongo abelii | 78.67 | 0.0 | 982 |
| LLPS-Pof-2340 | Poecilia formosa | 76.25 | 0.0 | 1164 |
| LLPS-Xim-1472 | Xiphophorus maculatus | 75.99 | 0.0 | 1163 |
| LLPS-Scm-1809 | Scophthalmus maximus | 75.58 | 0.0 | 1165 |
| LLPS-Leo-3178 | Lepisosteus oculatus | 74.34 | 0.0 | 1194 |
| LLPS-Cas-0850 | Carlito syrichta | 74.31 | 0.0 | 886 |
| LLPS-Orn-2439 | Oreochromis niloticus | 73.37 | 0.0 | 1142 |
| LLPS-Ten-1953 | Tetraodon nigroviridis | 73.28 | 0.0 | 1133 |
| LLPS-Icp-2653 | Ictalurus punctatus | 72.94 | 0.0 | 1132 |
| LLPS-Gaa-3050 | Gasterosteus aculeatus | 72.93 | 0.0 | 1134 |
| LLPS-Scf-3434 | Scleropages formosus | 72.87 | 0.0 | 1183 |
| LLPS-Tar-2994 | Takifugu rubripes | 72.34 | 0.0 | 1117 |
| LLPS-Orl-2092 | Oryzias latipes | 71.6 | 0.0 | 1065 |
| LLPS-Aon-3220 | Aotus nancymaae | 70.62 | 0.0 | 1160 |
| LLPS-Dio-1209 | Dipodomys ordii | 69.45 | 0.0 | 1150 |
| LLPS-Orc-3851 | Oryctolagus cuniculus | 68.73 | 0.0 | 1112 |
| LLPS-Ova-0679 | Ovis aries | 68.35 | 0.0 | 1111 |
| LLPS-Dar-2505 | Danio rerio | 68.26 | 0.0 | 1118 |
| LLPS-Nol-3198 | Nomascus leucogenys | 67.27 | 0.0 | 1088 |
| LLPS-Fec-1229 | Felis catus | 63.14 | 0.0 | 904 |
| LLPS-Ora-0566 | Ornithorhynchus anatinus | 61.61 | 0.0 | 892 |
| LLPS-Drm-1964 | Drosophila melanogaster | 45.67 | 2e-86 | 298 |