LLPS-Mam-a931
SCAI
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Protein SCAI |
| Gene Name: | SCAI |
| Ensembl Gene: | ENSMMUG00000020633.3 |
| Ensembl Protein: | ENSMMUP00000044468.1 |
| Organism: | Macaca mulatta |
| Taxa ID: | 9544 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMMUT00000069556.1 | ENSMMUP00000044468.1 |
| Ensembl | ENSMMUT00000062485.1 | ENSMMUP00000059082.1 |
| Ensembl | ENSMMUT00000029029.3 | ENSMMUP00000027162.3 |
| UniProt | A0A1D5Q8V0, A0A1D5Q8V0_MACMU | |
| GeneBank | JSUE03014223, JSUE03014225, JSUE03014226, JSUE03014222, JSUE03014228, JSUE03014227, JSUE03014224 | |
| RefSeq | XM_015116845.1 | XP_014972331.1 |
| Entrez | 712803 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MVRGARQPQQ PRSRLAPRLT GTVEKPPRKR RSSIRDSGDS SHSQSQGERY QHFTEKTEFA 60 61 LKEIMSSGGA EDDIPQGERK TVTDFCYLLD KSKQLFNGLR DLPQYGQKQW QSYFGRTFDV 120 121 YTKLWKFQQQ HRQVLDNRYG LKRWQIGEIA SKIGQLYYHY YLRTSETSYL NEAFSFYSAI 180 181 RQRSYYSQVN KEDRPELVVK KLRYYARFIV VCLLLNKMDV VKDLVKELSD EIEDYTHRFN 240 241 TEDQVEWNLV LQEVAAFIEA DPVMVLNDDN TIVITSNRLA ETGAPLLEQG MIVGQLSLAD 300 301 ALIIGNCNNQ VKFSELTVDM FRMLQALERE PMNLASQMNK PGMQESADKP TRRENPHKYL 360 361 LYKPTFSQLY TFLAASFKEL PANSVLLIYL SATGVFPTGR SDSEGPYDFG GVLTNSNRDI 420 421 INGDAIHKRN QSHKEMHCLH PGDLYPFTRK PLFIIVDSSN SVAYKNFTNL FGQPLVCLLS 480 481 PTAYPKALQD QSQRGSLFTL FLNNPLMAFL FVSGLSSMRR GLWEKCQEYL RKINRDIAQL 540 541 LTHSRSIDQA FLQFFGDEFL RLLLTRFIFC SATMRMHKIF RETRNYPESY PQLPRDETVE 600 601 NPHLQKHILE LASILDVRNV FFENTIDDY 629 |
| Nucleotide CDS Sequence (FASTA) |
1 AGTATCAGAG ATTCTGGTGA TAGCAGTCAT TCACAATCTC AAGGGGAAAG ATATCAACAT 60 61 TTCACTGAAA AGACTGAATT TGCTCTTAAA GAAATCATGT CCTCTGGAGG TGCTGAAGAT 120 121 GATATCCCAC AGGGAGAGAG GAAAACAGTT ACAGATTTTT GTTATCTTCT GGATAAATCT 180 181 AAGCAACTGT TCAATGGGTT AAGAGATTTG CCACAATATG GACAGAAGCA GTGGCAGTCC 240 241 TATTTTGGAA GAACTTTTGA TGTTTACACC AAACTCTGGA AGTTCCAGCA GCAGCATCGA 300 301 CAAGTCTTGG ATAATCGGTA TGGCTTGAAG CGCTGGCAAA TAGGAGAAAT TGCTTCCAAG 360 361 ATTGGGCAGC TATACTATCA TTATTACTTA CGCACATCTG AAACCAGCTA TCTGAATGAG 420 421 GCTTTTTCCT TCTATTCTGC AATCAGACAG AGATCATATT ATTCTCAAGT CAATAAAGAA 480 481 GACAGACCTG AATTAGTAGT TAAGAAGTTA CGATATTATG CAAGATTTAT AGTAGTTTGT 540 541 CTTCTTCTCA ACAAAATGGA TGTTGTAAAG GATCTGGTAA AGGAATTGTC AGATGAAATT 600 601 GAAGATTATA CTCACCGATT TAATACTGAA GATCAAGTGG AATGGAACTT GGTGCTTCAA 660 661 GAAGTAGCAG CTTTCATTGA GGCGGACCCT GTAATGGTAT TAAATGATGA TAATACCATC 720 721 GTTATCACAT CAAATCGCCT TGCTGAAACA GGAGCCCCAT TGCTGGAACA GGGCATGATT 780 781 GTGGGACAGT TGTCTCTGGC TGATGCACTC ATTATTGGTA ATTGTAATAA CCAGGTTAAG 840 841 TTCAGTGAAC TAACTGTTGA CATGTTCCGG ATGTTACAAG CTCTGGAAAG GGAGCCAATG 900 901 AATTTAGCTT CCCAGATGAA TAAACCAGGA ATGCAGGAAT CAGCTGACAA GCCTACTAGA 960 961 CGAGAAAATC CCCACAAGTA TCTTCTCTAT AAACCAACCT TCAGCCAACT ATATACTTTC 1020 1021 TTAGCAGCAT CTTTTAAGGA GCTGCCTGCC AATAGTGTGC TTCTGATTTA CCTGTCGGCC 1080 1081 ACTGGCGTTT TCCCCACAGG TCGTTCTGAT AGTGAAGGTC CTTATGATTT TGGAGGTGTA 1140 1141 CTTACTAATA GTAACCGGGA TATTATTAAT GGAGATGCTA TCCACAAACG AAATCAGTCC 1200 1201 CACAAGGAAA TGCAC 1215 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Nuclear membrane | |
Cellular Component | Nucleus | |
Molecular Function | Transcription corepressor activity | |
Biological Process | Negative regulation of cell migration | |
Biological Process | Negative regulation of Rho protein signal transduction | |
Biological Process | Transcription, DNA-templated |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a963 | Homo sapiens | 0.0 | 1309 | undefined |
| LLPS-Mum-a948 | Mus musculus | 0.0 | 1229 | undefined |