• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mam-4578
USP22

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ubiquitinyl hydrolase 1
Gene Name: USP22
Ensembl Gene: ENSMMUG00000005377.3
Ensembl Protein: ENSMMUP00000058349.1
Organism: Macaca mulatta
Taxa ID: 9544
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVSRPEPEGE  AMDAELAVAP  PGCSHLGSFK  VDNWKQNLRA  IYQCFVWSGT  AEARKRKAKS  60
61    CICHVCGVHL  NRLHSCLYCV  FFGCFTKKHI  HEHAKSKRHN  LAIDLMYGGI  YCFLCQDYIY  120
121   DKDMEIIAKE  EQRKAWKMQG  AGEKFSTWEP  TKRELELLKH  NPKRRKITSN  CTIGLRGLIN  180
181   LGNTCFMNCI  VQALTHTPLL  RDFFLSDRHR  CEMQSPSSCL  VCEMSSLFQE  FYSGHRSPHI  240
241   PYKLLHLVWT  HARHLAGYEQ  QDAHEFLIAA  LDVLHRHCKG  DDNGKKANNP  NHCNCIIDQI  300
301   FTGGLQSDVT  CQVCHGVSTT  IDPFWDISLD  LPGSSTPFWP  LSPGSEGNVV  NGESHVSGTT  360
361   TLTDCLRRFT  RPEHLGSSAK  IKCSGCHSYQ  ESTKQLTMKK  LPIVACFHLK  RFEHSAKLRR  420
421   KITTYVSFPL  ELDMTPFMAS  SKESRMNGQY  QQPTDSLNND  NKYSLFAVVN  HQGTLESGHY  480
481   TSFIRQHKDQ  WFKCDDAIIT  KASIKDVLDS  EGYLLFYHKQ  FLEYE  525
Nucleotide CDS Sequence (FASTA)
1     ATGGCGCCGG  GTTGGCCCTC  GCTATCCGCG  GGCTCCCGAC  AGGAGGTGCC  GCAGCTTGAG  60
61    GCAGGGAGCG  GCGCGGAGCA  GTTCCAGCCC  CGAGCCGCGG  CACTGCAGGG  CCCGACCCAG  120
121   GCCAAGTCCT  GCATCTGCCA  TGTCTGTGGC  GTCCACCTCA  ACAGGCTGCA  TTCCTGCCTC  180
181   TACTGCGTCT  TCTTCGGCTG  TTTCACGAAG  AAGCACATTC  ACGAGCATGC  GAAGTCAAAG  240
241   CGGCACAACC  TGGCCATTGA  TCTGATGTAC  GGAGGCATCT  ACTGCTTTCT  GTGCCAGGAC  300
301   TACATCTACG  ACAAAGACAT  GGAAATAATC  GCCAAGGAGG  AGCAGCGGAA  GGCTTGGAAA  360
361   ATGCAAGGCG  CTGGAGAGAA  GTTTTCAACT  TGGGAACCAA  CCAAACGGGA  GCTTGAACTG  420
421   CTGAAGCACA  ACCCAAAAAG  GAGAAAGATC  ACCTCGAACT  GCACCATAGG  TCTGCGCGGG  480
481   CTCATCAACC  TTGGGAACAC  GTGCTTCATG  AACTGCATCG  TGCAGGCGCT  GACCCACACG  540
541   CCACTTCTGC  GGGACTTCTT  CCTGTCTGAC  AGGCACCGCT  GTGAGATGCA  GAGCCCCAGC  600
601   TCCTGTCTGG  TCTGTGAGAT  GTCCTCACTG  TTTCAGGAGT  TTTACTCCGG  ACACCGGTCC  660
661   CCTCACATCC  CTTATAAGTT  GCTGCACCTG  GTGTGGACCC  ACGCGAGGCA  CCTGGCAGGC  720
721   TACGAGCAGC  AGGATGCCCA  CGAGTTCCTC  ATCGCAGCCC  TGGACGTGCT  CCACCGACAC  780
781   TGCAAAGGTG  ATGACAACGG  GAAGAAGGCC  AACAACCCCA  ACCACTGCAA  CTGCATCATA  840
841   GACCAGATCT  TCACGGGCGG  GCTGCAGTCA  GACGTCACCT  GCCAAGTTTG  CCATGGAGTC  900
901   TCCACCACCA  TCGACCCCTT  CTGGGACATC  AGCTTGGATC  TCCCCGGCTC  TTCCACCCCG  960
961   TTCTGGCCCC  TGAGCCCAGG  GAGCGAGGGC  AACGTGGTAA  ACGGGGAAAG  CCACGTGTCG  1020
1021  GGAACCACCA  CGCTCACGGA  CTGCCTGCGA  CGATTCACCA  GACCAGAGCA  CTTGGGCAGC  1080
1081  AGCGCCAAGA  TCAAATGCAG  CGGTTGCCAT  AGCTACCAGG  AGTCCACGAA  GCAGCTCACT  1140
1141  ATGAAGAAAC  TGCCCATCGT  AGCCTGTTTT  CATCTCAAAC  GATTTGAACA  CTCAGCCAAG  1200
1201  CTGCGGCGGA  AGATCACCAC  ATATGTGTCC  TTCCCCCTGG  AGCTGGATAT  GACCCCTTTC  1260
1261  ATGGCCTCCA  GCAAAGAGAG  CAGGATGAAT  GGACAGTACC  AGCAGCCCAC  GGACAGTCTC  1320
1321  AACAATGACA  ACAAGTATTC  CCTGTTTGCT  GTTGTTAACC  ATCAAGGGAC  CTTGGAGAGT  1380
1381  GGCCATTACA  CCAGCTTTAT  CCGGCAGCAC  AAAGACCAGT  GGTTCAAGTG  TGACGATGCC  1440
1441  ATCATCACCA  AGGCCAGCAT  CAAGGACGTG  CTGGACAGTG  AAGGGTACTT  GCTGTTCTAT  1500
1501  CACAAACAGT  TCCTGGAATA  TGAGTAG  1527

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-3738Macaca nemestrina100.00.01106
LLPS-Maf-2156Macaca fascicularis100.00.01106
LLPS-Chs-3765Chlorocebus sabaeus100.00.01106
LLPS-Cea-1835Cercocebus atys100.00.01106
LLPS-Poa-4637Pongo abelii99.810.01103
LLPS-Rhb-4509Rhinopithecus bieti99.810.01105
LLPS-Paa-4162Papio anubis99.810.01105
LLPS-Hos-0349Homo sapiens99.620.01103
LLPS-Aon-4579Aotus nancymaae99.620.01104
LLPS-Pat-2355Pan troglodytes99.430.01102
LLPS-Caj-0198Callithrix jacchus99.430.01100
LLPS-Orc-4270Oryctolagus cuniculus99.020.01066
LLPS-Ict-2479Ictidomys tridecemlineatus98.480.01093
LLPS-Fec-2189Felis catus98.10.01090
LLPS-Ran-2904Rattus norvegicus98.10.01089
LLPS-Caf-1497Canis familiaris98.090.0 976
LLPS-Loa-1015Loxodonta africana98.080.0 972
LLPS-Ova-4170Ovis aries98.080.0 969
LLPS-Fud-2586Fukomys damarensis98.080.0 968
LLPS-Mal-2230Mandrillus leucophaeus97.920.0 987
LLPS-Cap-3795Cavia porcellus97.90.01083
LLPS-Mum-3173Mus musculus97.90.01087
LLPS-Mea-0614Mesocricetus auratus97.710.01087
LLPS-Bot-2629Bos taurus97.470.01061
LLPS-Eqc-2692Equus caballus97.330.01080
LLPS-Gog-0409Gorilla gorilla96.560.01062
LLPS-Urm-0157Ursus maritimus96.540.0 946
LLPS-Tag-1200Taeniopygia guttata96.380.0 962
LLPS-Sah-2564Sarcophilus harrisii96.312e-151 439
LLPS-Sus-4238Sus scrofa95.980.01069
LLPS-Pap-2535Pan paniscus95.780.01041
LLPS-Nol-2167Nomascus leucogenys95.620.01047
LLPS-Mup-0887Mustela putorius furo95.610.01049
LLPS-Otg-4356Otolemur garnettii95.190.01081
LLPS-Mod-3749Monodelphis domestica94.880.01031
LLPS-Lac-3633Latimeria chalumnae93.90.01023
LLPS-Fia-1499Ficedula albicollis93.490.0 939
LLPS-Meg-2030Meleagris gallopavo93.390.0 953
LLPS-Anp-2075Anas platyrhynchos93.390.0 953
LLPS-Scf-0051Scleropages formosus92.910.01007
LLPS-Icp-2461Ictalurus punctatus92.720.01008
LLPS-Dar-1025Danio rerio92.520.0 999
LLPS-Pes-3620Pelodiscus sinensis92.460.0 954
LLPS-Asm-3767Astyanax mexicanus92.320.01001
LLPS-Gaga-2064Gallus gallus92.00.01018
LLPS-Xim-0689Xiphophorus maculatus91.80.0 998
LLPS-Scm-4024Scophthalmus maximus91.540.0 991
LLPS-Tar-0958Takifugu rubripes91.210.0 995
LLPS-Xet-2571Xenopus tropicalis91.20.01011
LLPS-Ten-0648Tetraodon nigroviridis91.030.0 999
LLPS-Orl-3501Oryzias latipes91.00.0 990
LLPS-Pof-3818Poecilia formosa89.870.0 989
LLPS-Orn-0949Oreochromis niloticus89.670.0 974
LLPS-Anc-3359Anolis carolinensis88.890.01006
LLPS-Ora-2250Ornithorhynchus anatinus86.550.0 921
LLPS-Gaa-2875Gasterosteus aculeatus86.10.0 928
LLPS-Dio-1299Dipodomys ordii84.860.0 923
LLPS-Leo-3741Lepisosteus oculatus83.650.0 909
LLPS-Tut-1971Tursiops truncatus81.850.0 889
LLPS-Aim-4326Ailuropoda melanoleuca81.820.0 906
LLPS-Myl-0047Myotis lucifugus81.630.0 902
LLPS-Cii-1354Ciona intestinalis57.828e-146 431
LLPS-Cis-1083Ciona savignyi55.850.0 603
LLPS-Drm-1218Drosophila melanogaster51.231e-179 522
LLPS-Coc-1257Corchorus capsularis42.933e-83 282
LLPS-Orbr-0376Oryza brachyantha41.951e-91 292
LLPS-Orp-2390Oryza punctata40.444e-83 269
LLPS-Ors-0993Oryza sativa40.19e-92 299
LLPS-Tra-2524Triticum aestivum39.451e-83 271
LLPS-Abg-1921Absidia glauca38.816e-104 329
LLPS-Amt-2205Amborella trichopoda37.994e-117 363
LLPS-Nia-2275Nicotiana attenuata37.883e-103 328
LLPS-Sol-2279Solanum lycopersicum37.715e-102 324
LLPS-Thc-1624Theobroma cacao37.642e-104 330
LLPS-Tum-0662Tuber melanosporum37.337e-98 313
LLPS-Met-2282Medicago truncatula37.242e-100 324
LLPS-Brr-0495Brassica rapa37.185e-82 271
LLPS-Dac-0891Daucus carota36.891e-105 334
LLPS-Viv-1171Vitis vinifera36.829e-105 332
LLPS-Prp-2296Prunus persica36.71e-106 338
LLPS-Gor-1861Gossypium raimondii36.63e-106 337
LLPS-Hea-1826Helianthus annuus36.336e-95 306
LLPS-Mae-0185Manihot esculenta36.191e-109 345
LLPS-Kop-0062Komagataella pastoris35.845e-76 255
LLPS-Sei-1557Setaria italica35.88e-96 308
LLPS-Bro-1471Brassica oleracea35.54e-83 280
LLPS-Pot-2384Populus trichocarpa35.54e-105 334
LLPS-Arl-0219Arabidopsis lyrata35.221e-86 284
LLPS-Orm-1595Oryza meridionalis35.22e-97 318
LLPS-Art-2797Arabidopsis thaliana35.26e-87 285
LLPS-Scj-0654Schizosaccharomyces japonicus35.172e-77 256
LLPS-Sem-1124Selaginella moellendorffii35.152e-98 315
LLPS-Brn-2954Brassica napus35.071e-84 280
LLPS-Orb-2047Oryza barthii35.042e-96 310
LLPS-Orr-1649Oryza rufipogon34.953e-99 318
LLPS-Org-1411Oryza glaberrima34.953e-99 318
LLPS-Orgl-0377Oryza glumaepatula34.952e-99 318
LLPS-Orni-2413Oryza nivara34.955e-99 317
LLPS-Cus-2320Cucumis sativus34.943e-105 334
LLPS-Phv-2349Phaseolus vulgaris34.831e-101 325
LLPS-Glm-2166Glycine max34.548e-102 325
LLPS-Php-0700Physcomitrella patens34.397e-91 297
LLPS-Scc-0242Schizosaccharomyces cryophilus34.269e-78 258
LLPS-Pytr-0118Pyrenophora triticirepentis34.091e-80 267
LLPS-Vir-0587Vigna radiata34.081e-102 327
LLPS-Mua-2480Musa acuminata34.03e-92 298
LLPS-Aso-1208Aspergillus oryzae33.992e-44 164
LLPS-Brd-1222Brachypodium distachyon33.995e-94 304
LLPS-Lem-1368Leptosphaeria maculans33.972e-82 272
LLPS-Fus-1351Fusarium solani33.863e-61 214
LLPS-Crn-0819Cryptococcus neoformans33.847e-73 249
LLPS-Via-2423Vigna angularis33.791e-101 325
LLPS-Beb-1500Beauveria bassiana33.711e-61 217
LLPS-Trr-1582Trichoderma reesei33.263e-59 208
LLPS-Pyt-1285Pyrenophora teres33.084e-73 247
LLPS-Map-1105Magnaporthe poae33.048e-62 217
LLPS-Asf-0853Aspergillus flavus33.013e-64 220
LLPS-Zyt-1038Zymoseptoria tritici32.914e-67 230
LLPS-Gag-0142Gaeumannomyces graminis32.824e-63 221
LLPS-Fuo-0003Fusarium oxysporum32.818e-62 217
LLPS-Fuv-1505Fusarium verticillioides32.814e-62 218
LLPS-Miv-1571Microbotryum violaceum32.753e-70 238
LLPS-Cogr-0853Colletotrichum graminicola32.741e-59 211
LLPS-Asn-1473Aspergillus nidulans32.566e-63 219
LLPS-Cog-1269Colletotrichum gloeosporioides32.531e-59 211
LLPS-Phn-0731Phaeosphaeria nodorum32.312e-70 240
LLPS-Cas-3066Carlito syrichta32.161e-44 174
LLPS-Scs-0379Sclerotinia sclerotiorum32.147e-58 207
LLPS-Mao-1167Magnaporthe oryzae31.924e-61 216
LLPS-Blg-1238Blumeria graminis31.879e-51 187
LLPS-Ast-1011Aspergillus terreus31.811e-59 208
LLPS-Asfu-1233Aspergillus fumigatus31.633e-61 215
LLPS-Nef-1411Neosartorya fischeri31.633e-61 215
LLPS-Scp-1494Schizosaccharomyces pombe31.512e-66 228
LLPS-Asni-0404Aspergillus niger31.486e-60 211
LLPS-Sac-1170Saccharomyces cerevisiae31.391e-59 210
LLPS-Yal-0156Yarrowia lipolytica30.819e-54 196
LLPS-Dos-0832Dothistroma septosporum30.745e-66 228
LLPS-Coo-1343Colletotrichum orbiculare30.719e-59 209
LLPS-Asc-0937Aspergillus clavatus30.415e-64 223
LLPS-Mel-1242Melampsora laricipopulina30.413e-45 170
LLPS-Asg-0133Ashbya gossypii30.45e-57 203
LLPS-Trv-1225Trichoderma virens29.759e-61 214
LLPS-Nec-1618Neurospora crassa29.722e-64 224