LLPS-Mam-4311
GEMIN4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Uncharacterized protein |
| Gene Name: | GEMIN4 |
| Ensembl Gene: | ENSMMUG00000030401.2 |
| Ensembl Protein: | ENSMMUP00000035467.2 |
| Organism: | Macaca mulatta |
| Taxa ID: | 9544 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Gemini of cajal body, Nuclear speckle | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMMUT00000042462.2 | ENSMMUP00000035467.2 |
| Ensembl | ENSMMUT00000078180.1 | ENSMMUP00000047068.1 |
| Ensembl | ENSMMUT00000057270.1 | ENSMMUP00000056932.1 |
| UniProt | F7DPP6, F7DPP6_MACMU | |
| GeneBank | JSUE03015665 | |
| RefSeq | XM_015118154.1 | XP_014973640.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTILHGGFLL AEQLFRPKAL AELTKSDWER VGRPIVEALR EISSAAAHSQ PFAWKKKALI 60 61 IIWAKVLQPH PVTPSDTETR WQEDLFFSVG NMIPTINHTV LFELLKSLEA SGLFIQLLMA 120 121 LPTTIRHAEL ERFLEHVTVD TSSEDVAFFL DVWWEMMKHK GHLQDPLLSQ FSAMAHKYLP 180 181 ALDEFPHPPK RLRSDPDVCP TMPLLSMLLR GLTQIQSQIL GPGRRCCALA NLADMLTVFA 240 241 LMEDDPQEVS ATMYLDKLAT VISVWNSDTQ NPYHQQALAE KVKEAERDVS LTSLAKLPSE 300 301 TIFVGCEFLH RLLREWGEEL QAVLRSSQGT SYDSYRLCDS LTSFSQNATL YLNRTSLSKE 360 361 ERQVVSELAE CVRDFLRKTS TVVKNRALED ITASIAMAVI QQKMDRHMEV CHIFASEKKW 420 421 AFSEEWVACL GSNRALFREP DLVLRLLETV IDVSTTDRAV PESQIRQVIH LVLECYADLS 480 481 LPDKNKVLAG ILHSWGRKGL SEKLLAYVEG FQEDLNTTFN QLTQSASEQG LAKAVASVAR 540 541 LIIVHPEVTV KKMCSLAVVN LGAHKFLAQI LTAFPALRFV EEQSPNSSAT FMVSCLKETV 600 601 WMKFSTPKEE KQFLELLNCL MHPVKPQGIP VAALLEPEEV LREFVLPFLR LDVEEVDLSL 660 661 KIFIQTLEAD TCREEYWLQT CSPFPLLFSL CQLLDGFSKY WQLPKEKRCL SLDRKDLAIH 720 721 ILELLCEIVS ANAETFSPDA WVKSLSWLHR KLEQLDWTVG LRLKNFFEGH FKCEVPATLF 780 781 EICKLSEDEW TSQAHPGYGA GTGLLAWMEC CCVSSGISER MLSLLVVDVG NPEEVRLFSK 840 841 GFLVALVQVM PWCSPQEWQR LHQLTRRLLE KQLLHVPYSL EYIQFVPLLN LKPFAQELQL 900 901 SVLFLRTFQF LCSQSCHNWL PLEGWNHVVK LLCGSLTRLL DSVRLIQSAG PWAQGPEQDL 960 961 TQEALFVYTQ VFCHALHIMA MLHPEVCEPL YVLALETLTC YETLSKTNPS VSSLLQRAHE 1020 1021 QRFLKSIAEG ISPEERRQTL LQKMNSF 1047 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACTATTC TGCATGGAGG CTTCTTGCTG GCCGAGCAGC TGTTCCGCCC CAAGGCACTG 60 61 GCAGAATTGA CAAAGTCTGA CTGGGAACGT GTTGGACGCC CCATCGTGGA GGCCTTAAGG 120 121 GAGATCTCCT CGGCCGCAGC ACACTCCCAG CCCTTTGCCT GGAAGAAGAA AGCCCTGATT 180 181 ATCATCTGGG CCAAGGTTCT GCAGCCGCAC CCCGTGACCC CCTCCGACAC GGAGACACGG 240 241 TGGCAGGAAG ACCTGTTCTT CTCGGTGGGC AACATGATCC CCACCATCAA CCACACTGTC 300 301 CTTTTTGAGC TGCTCAAATC CCTGGAAGCT TCTGGACTCT TTATCCAGCT CCTGATGGCC 360 361 CTGCCCACCA CCATCCGCCA TGCAGAACTA GAGCGCTTTC TGGAGCACGT GACCGTTGAC 420 421 ACTTCTTCTG AAGACGTGGC CTTCTTCCTG GACGTCTGGT GGGAGATGAT GAAGCACAAG 480 481 GGTCACCTGC AGGACCCCCT GCTCTCCCAG TTTAGTGCAA TGGCCCATAA GTACCTGCCT 540 541 GCCTTAGATG AGTTCCCCCA TCCTCCAAAG AGGCTTAGGT CAGACCCAGA TGTGTGCCCC 600 601 ACCATGCCCC TGTTGTCCAT GCTGCTCCGC GGGCTGACGC AGATCCAAAG TCAGATCCTG 660 661 GGCCCGGGGA GAAGGTGCTG TGCGCTGGCC AACCTGGCCG ACATGCTGAC CGTGTTTGCG 720 721 CTGATGGAGG ACGACCCCCA GGAGGTGTCT GCAACCATGT ATCTGGACAA ACTGGCCACC 780 781 GTGATCTCCG TGTGGAACTC GGACACCCAG AACCCCTACC ACCAGCAGGC GCTGGCAGAG 840 841 AAGGTGAAGG AGGCAGAACG GGATGTCAGC CTGACCTCAC TGGCCAAACT CCCCAGTGAG 900 901 ACCATTTTCG TGGGCTGCGA GTTCCTGCAC CGCCTGCTGC GGGAGTGGGG GGAGGAGCTG 960 961 CAGGCCGTGC TCCGCAGCAG CCAGGGGACA AGTTATGACA GCTACAGGCT ATGCGACAGT 1020 1021 CTGACTTCCT TCAGCCAGAA CGCAACGCTC TACCTGAACC GCACCAGCCT GTCCAAGGAG 1080 1081 GAGAGGCAGG TGGTCTCTGA GCTGGCGGAG TGTGTCAGGG ACTTCCTGAG GAAAACGAGC 1140 1141 ACGGTGGTGA AGAACAGGGC CTTGGAGGAC ATCACAGCTT CCATCGCCAT GGCCGTCATC 1200 1201 CAGCAGAAGA TGGACCGTCA TATGGAAGTG TGCCACATTT TTGCTTCTGA GAAGAAGTGG 1260 1261 GCCTTCTCGG AGGAGTGGGT AGCCTGCCTG GGGAGTAACA GGGCCCTCTT CCGAGAGCCA 1320 1321 GACTTGGTGT TGAGGCTGCT GGAAACAGTG ATAGACGTCA GCACAACTGA CAGGGCCGTC 1380 1381 CCCGAGTCTC AGATCCGGCA GGTGATCCAC CTGGTCCTGG AATGTTATGC AGACCTCTCC 1440 1441 TTGCCAGATA AAAACAAAGT CCTTGCAGGT ATCCTGCATT CCTGGGGGCG AAAGGGCCTC 1500 1501 TCTGAAAAGT TGCTGGCTTA TGTGGAAGGT TTTCAGGAAG ACCTCAATAC GACTTTTAAC 1560 1561 CAGCTCACTC AGAGTGCCTC CGAACAGGGC TTGGCGAAAG CTGTGGCCTC CGTGGCCCGC 1620 1621 CTGATCATAG TGCACCCGGA AGTCACGGTG AAGAAAATGT GCAGCCTGGC TGTGGTCAAT 1680 1681 CTTGGCGCCC ACAAGTTCCT GGCCCAGATT CTCACTGCCT TCCCTGCCCT TCGGTTCGTG 1740 1741 GAAGAGCAGA GTCCCAATTC ATCTGCCACG TTCATGGTGT CATGCCTCAA AGAAACCGTC 1800 1801 TGGATGAAGT TCTCTACACC CAAGGAAGAA AAGCAATTTT TAGAGCTCCT GAACTGCCTG 1860 1861 ATGCATCCCG TGAAGCCCCA GGGGATTCCA GTAGCTGCTC TTCTTGAGCC AGAGGAGGTG 1920 1921 CTGAGGGAGT TTGTCCTGCC TTTCTTGAGG TTAGATGTTG AAGAAGTAGA CCTCAGTCTG 1980 1981 AAGATCTTCA TCCAGACTCT AGAAGCAGAC ACGTGCCGAG AGGAGTACTG GCTCCAGACC 2040 2041 TGCTCCCCGT TTCCACTCCT CTTCAGCTTG TGCCAGCTCT TGGATGGCTT CAGCAAATAC 2100 2101 TGGCAGCTCC CCAAGGAGAA GCGGTGCCTC TCTTTGGATA GGAAGGATCT GGCAATCCAT 2160 2161 ATCCTGGAGC TCCTGTGTGA AATCGTATCA GCCAATGCCG AGACCTTCTC CCCGGACGCC 2220 2221 TGGGTCAAGT CCCTGTCCTG GCTCCACCGC AAGTTAGAAC AGCTGGACTG GACTGTGGGC 2280 2281 CTGAGGCTGA AGAACTTCTT TGAGGGGCAC TTCAAATGTG AAGTGCCAGC CACACTTTTT 2340 2341 GAGATCTGTA AGCTTTCGGA AGATGAGTGG ACCTCCCAGG CCCACCCAGG CTACGGAGCC 2400 2401 GGCACGGGGC TCCTGGCCTG GATGGAGTGC TGCTGTGTCT CCAGTGGCAT CTCAGAGAGG 2460 2461 ATGCTGTCTC TCTTGGTGGT GGACGTGGGC AATCCTGAGG AGGTCAGACT GTTCAGCAAA 2520 2521 GGCTTTCTGG TGGCCCTGGT ACAAGTCATG CCTTGGTGCA GCCCTCAGGA GTGGCAGCGC 2580 2581 CTTCACCAGC TGACCAGGAG ACTGCTGGAG AAGCAGCTTC TCCATGTCCC GTATAGCCTG 2640 2641 GAATATATTC AGTTTGTTCC CCTGCTCAAC CTGAAGCCGT TTGCCCAGGA GCTGCAACTC 2700 2701 TCCGTACTCT TCCTGAGGAC TTTCCAGTTT CTCTGCAGCC AGAGCTGTCA TAATTGGCTT 2760 2761 CCTCTGGAGG GCTGGAACCA TGTGGTCAAA CTCCTCTGTG GCAGTCTGAC CCGCCTGCTG 2820 2821 GACTCAGTCA GGCTGATACA GTCAGCTGGC CCTTGGGCCC AAGGACCAGA GCAGGACCTG 2880 2881 ACCCAGGAAG CCCTGTTCGT TTACACCCAG GTGTTCTGCC ATGCTCTGCA TATCATGGCC 2940 2941 ATGCTCCACC CGGAGGTCTG TGAGCCACTC TACGTTTTAG CCTTGGAAAC CCTCACCTGC 3000 3001 TATGAGACTC TGAGCAAGAC CAACCCTTCT GTCAGCTCCT TGCTCCAGAG GGCGCACGAG 3060 3061 CAGCGCTTCT TAAAGTCCAT TGCTGAGGGC ATCAGCCCGG AAGAACGGCG CCAAACCCTG 3120 3121 TTGCAGAAGA TGAACAGCTT CTGA 3144 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Maf-0968 | Macaca fascicularis | 99.9 | 0.0 | 2105 |
| LLPS-Man-2266 | Macaca nemestrina | 99.62 | 0.0 | 2100 |
| LLPS-Mal-0147 | Mandrillus leucophaeus | 99.24 | 0.0 | 2093 |
| LLPS-Paa-2826 | Papio anubis | 99.04 | 0.0 | 2088 |
| LLPS-Chs-0355 | Chlorocebus sabaeus | 98.95 | 0.0 | 2088 |
| LLPS-Cea-1456 | Cercocebus atys | 98.85 | 0.0 | 2088 |
| LLPS-Rhb-2940 | Rhinopithecus bieti | 98.28 | 0.0 | 2072 |
| LLPS-Poa-4462 | Pongo abelii | 96.28 | 0.0 | 2039 |
| LLPS-Gog-0320 | Gorilla gorilla | 95.99 | 0.0 | 2039 |
| LLPS-Pat-0052 | Pan troglodytes | 95.99 | 0.0 | 2036 |
| LLPS-Pap-1199 | Pan paniscus | 95.89 | 0.0 | 2033 |
| LLPS-Hos-2195 | Homo sapiens | 95.8 | 0.0 | 2029 |
| LLPS-Nol-0156 | Nomascus leucogenys | 90.74 | 0.0 | 1886 |
| LLPS-Aon-3883 | Aotus nancymaae | 89.11 | 0.0 | 1880 |
| LLPS-Eqc-3305 | Equus caballus | 87.5 | 0.0 | 1847 |
| LLPS-Caj-2248 | Callithrix jacchus | 86.91 | 0.0 | 1801 |
| LLPS-Otg-4296 | Otolemur garnettii | 86.72 | 0.0 | 1825 |
| LLPS-Aim-2046 | Ailuropoda melanoleuca | 85.97 | 0.0 | 1809 |
| LLPS-Dio-2489 | Dipodomys ordii | 85.96 | 0.0 | 1839 |
| LLPS-Urm-1552 | Ursus maritimus | 85.88 | 0.0 | 1828 |
| LLPS-Caf-0947 | Canis familiaris | 85.4 | 0.0 | 1806 |
| LLPS-Mup-0231 | Mustela putorius furo | 85.31 | 0.0 | 1796 |
| LLPS-Myl-1041 | Myotis lucifugus | 85.2 | 0.0 | 1789 |
| LLPS-Fec-3220 | Felis catus | 84.92 | 0.0 | 1803 |
| LLPS-Bot-2256 | Bos taurus | 84.83 | 0.0 | 1793 |
| LLPS-Ova-1397 | Ovis aries | 84.73 | 0.0 | 1771 |
| LLPS-Orc-1586 | Oryctolagus cuniculus | 84.72 | 0.0 | 1810 |
| LLPS-Loa-0002 | Loxodonta africana | 84.64 | 0.0 | 1808 |
| LLPS-Ict-0224 | Ictidomys tridecemlineatus | 84.56 | 0.0 | 1813 |
| LLPS-Tut-2254 | Tursiops truncatus | 84.24 | 0.0 | 1771 |
| LLPS-Fud-4225 | Fukomys damarensis | 83.95 | 0.0 | 1794 |
| LLPS-Sus-4638 | Sus scrofa | 83.78 | 0.0 | 1756 |
| LLPS-Cap-3971 | Cavia porcellus | 83.67 | 0.0 | 1793 |
| LLPS-Mum-0051 | Mus musculus | 81.57 | 0.0 | 1745 |
| LLPS-Ran-1598 | Rattus norvegicus | 81.28 | 0.0 | 1741 |
| LLPS-Mea-2198 | Mesocricetus auratus | 81.28 | 0.0 | 1746 |
| LLPS-Mod-3220 | Monodelphis domestica | 72.83 | 0.0 | 1539 |
| LLPS-Sah-2101 | Sarcophilus harrisii | 72.16 | 0.0 | 1528 |
| LLPS-Ora-0151 | Ornithorhynchus anatinus | 56.65 | 0.0 | 1169 |
| LLPS-Pes-3459 | Pelodiscus sinensis | 52.19 | 0.0 | 1012 |
| LLPS-Gaga-0228 | Gallus gallus | 51.18 | 0.0 | 981 |
| LLPS-Meg-1045 | Meleagris gallopavo | 51.01 | 0.0 | 969 |
| LLPS-Fia-0335 | Ficedula albicollis | 50.38 | 0.0 | 943 |
| LLPS-Anc-3348 | Anolis carolinensis | 46.35 | 0.0 | 840 |
| LLPS-Lac-3362 | Latimeria chalumnae | 43.53 | 0.0 | 840 |
| LLPS-Xet-0052 | Xenopus tropicalis | 42.98 | 0.0 | 820 |
| LLPS-Leo-2687 | Lepisosteus oculatus | 38.97 | 0.0 | 688 |
| LLPS-Asm-0694 | Astyanax mexicanus | 37.38 | 0.0 | 610 |
| LLPS-Icp-0348 | Ictalurus punctatus | 37.38 | 0.0 | 617 |
| LLPS-Scf-0258 | Scleropages formosus | 35.57 | 2e-179 | 559 |
| LLPS-Ten-1977 | Tetraodon nigroviridis | 34.17 | 1e-166 | 525 |
| LLPS-Gaa-1822 | Gasterosteus aculeatus | 33.46 | 2e-160 | 509 |
| LLPS-Dar-3031 | Danio rerio | 33.15 | 1e-175 | 549 |
| LLPS-Pof-2045 | Poecilia formosa | 32.12 | 4e-148 | 478 |
| LLPS-Scm-1407 | Scophthalmus maximus | 31.92 | 3e-146 | 473 |
| LLPS-Tar-1330 | Takifugu rubripes | 31.81 | 1e-150 | 484 |
| LLPS-Orn-0880 | Oreochromis niloticus | 31.8 | 3e-147 | 474 |
| LLPS-Xim-1065 | Xiphophorus maculatus | 31.48 | 6e-146 | 472 |
| LLPS-Orl-0596 | Oryzias latipes | 30.76 | 7e-152 | 488 |