• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Mam-3235
CFL2

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Cofilin-2
Gene Name: CFL2, EGK_18105
Ensembl Gene: ENSMMUG00000039560.1
Ensembl Protein: ENSMMUP00000044119.1
Organism: Macaca mulatta
Taxa ID: 9544
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE


Protein Sequence (FASTA)
1     MASGVTVNDE  VIKVFNDMKV  RKSSTQEEIK  KRKKAVLFCL  SDDKRQIIVE  EAKQILVGDI  60
61    GDTVEDPYTS  FVKLLPLNDC  RYALYDATYE  TKESKKEDLV  FIFWAPESAP  LKSKMIYASS  120
121   KDAIKKKFTG  IKHEWQVNGL  DDIKDRSTLG  EKLGGNVVVS  LEGKPL  166
Nucleotide CDS Sequence (FASTA)
1     ATGGCTTCTG  GAGTTACAGT  GAATGATGAA  GTCATAAAAG  TTTTTAATGA  TATGAAAGTA  60
61    AGGAAATCTT  CTACACAAGA  GGAGATCAAA  AAGAGAAAGA  AAGCAGTTCT  CTTCTGTTTA  120
121   AGCGATGACA  AAAGACAAAT  AATTGTAGAG  GAAGCAAAGC  AGATCTTGGT  GGGTGACATT  180
181   GGTGATACTG  TAGAGGACCC  CTACACATCT  TTTGTGAAGT  TGCTACCTCT  GAATGATTGC  240
241   CGATATGCTT  TGTACGATGC  CACATACGAA  ACAAAAGAGT  CTAAGAAAGA  AGACCTAGTA  300
301   TTTATATTCT  GGGCTCCTGA  AAGTGCACCT  TTAAAAAGCA  AGATGATTTA  TGCTAGCTCT  360
361   AAAGATGCCA  TTAAAAAGAA  ATTTACAGGT  ATTAAACATG  AGTGGCAAGT  AAATGGCTTG  420
421   GATGATATTA  AGGACCGTTC  GACACTTGGA  GAGAAATTGG  GAGGCAATGT  AGTAGTTTCA  480
481   CTTGAAGGAA  AACCATTATA  A  501

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bot-2220Bos taurus100.01e-117 337
LLPS-Mup-0830Mustela putorius furo100.01e-117 337
LLPS-Paa-4704Papio anubis100.01e-117 337
LLPS-Mal-3808Mandrillus leucophaeus100.01e-117 337
LLPS-Sus-2850Sus scrofa100.01e-117 337
LLPS-Aon-1686Aotus nancymaae100.01e-117 337
LLPS-Cea-1169Cercocebus atys100.06e-113 325
LLPS-Chs-3975Chlorocebus sabaeus100.01e-116 334
LLPS-Maf-0977Macaca fascicularis100.01e-117 337
LLPS-Caj-2440Callithrix jacchus100.01e-117 337
LLPS-Gog-1674Gorilla gorilla100.01e-117 337
LLPS-Cap-2863Cavia porcellus100.01e-117 337
LLPS-Eqc-4742Equus caballus100.01e-117 337
LLPS-Poa-0519Pongo abelii100.01e-117 337
LLPS-Caf-1848Canis familiaris100.01e-117 337
LLPS-Nol-2054Nomascus leucogenys100.01e-117 337
LLPS-Loa-1998Loxodonta africana100.01e-116 334
LLPS-Man-4290Macaca nemestrina100.01e-117 337
LLPS-Fec-3635Felis catus100.01e-117 337
LLPS-Hos-4302Homo sapiens100.01e-117 337
LLPS-Pat-4176Pan troglodytes100.01e-117 337
LLPS-Pap-1752Pan paniscus100.01e-117 337
LLPS-Ran-4308Rattus norvegicus99.41e-116 335
LLPS-Mum-4701Mus musculus99.41e-116 335
LLPS-Ict-4126Ictidomys tridecemlineatus99.44e-117 335
LLPS-Rhb-3168Rhinopithecus bieti99.45e-115 330
LLPS-Ere-1041Erinaceus europaeus99.394e-116 333
LLPS-Gaga-3902Gallus gallus98.193e-115 331
LLPS-Pes-1640Pelodiscus sinensis98.193e-115 331
LLPS-Tag-1720Taeniopygia guttata98.183e-114 328
LLPS-Meg-0335Meleagris gallopavo98.183e-114 328
LLPS-Anc-0774Anolis carolinensis96.995e-114 328
LLPS-Asm-3674Astyanax mexicanus90.363e-107 310
LLPS-Dar-2484Danio rerio89.162e-106 308
LLPS-Scf-0855Scleropages formosus86.147e-104 302
LLPS-Ten-1500Tetraodon nigroviridis84.343e-100 293
LLPS-Mea-2696Mesocricetus auratus81.334e-95 280
LLPS-Tut-1549Tursiops truncatus80.724e-94 277
LLPS-Urm-4054Ursus maritimus80.722e-94 278
LLPS-Aim-1556Ailuropoda melanoleuca80.619e-94 278
LLPS-Myl-0634Myotis lucifugus80.611e-93 276
LLPS-Sah-1038Sarcophilus harrisii80.612e-94 278
LLPS-Otg-4483Otolemur garnettii80.128e-94 276
LLPS-Dio-1582Dipodomys ordii80.07e-93 274
LLPS-Ova-2840Ovis aries80.07e-93 274
LLPS-Cas-1223Carlito syrichta80.03e-92 273
LLPS-Fud-1877Fukomys damarensis79.495e-86 258
LLPS-Orc-3287Oryctolagus cuniculus77.349e-70 214
LLPS-Xet-3061Xenopus tropicalis72.291e-83 250
LLPS-Anp-2825Anas platyrhynchos70.33e-80 242
LLPS-Fia-1992Ficedula albicollis70.33e-80 242
LLPS-Ora-2610Ornithorhynchus anatinus68.482e-78 238
LLPS-Mod-0766Monodelphis domestica68.483e-78 236
LLPS-Icp-1754Ictalurus punctatus50.07e-45 151
LLPS-Pot-1973Populus trichocarpa36.844e-2191.3
LLPS-Mae-2492Manihot esculenta36.841e-2192.0
LLPS-Crn-0544Cryptococcus neoformans35.864e-1984.0
LLPS-Met-2276Medicago truncatula35.294e-1778.6
LLPS-Brn-1371Brassica napus35.062e-1985.9
LLPS-Orgl-0637Oryza glumaepatula35.02e-1779.7
LLPS-Sei-0672Setaria italica35.09e-1880.5
LLPS-Ori-2157Oryza indica35.02e-1779.7
LLPS-Orni-0455Oryza nivara35.02e-1779.7
LLPS-Orr-1319Oryza rufipogon35.02e-1779.7
LLPS-Orm-0693Oryza meridionalis35.02e-1779.7
LLPS-Zem-0291Zea mays35.02e-1779.3
LLPS-Sob-0295Sorghum bicolor35.08e-1880.5
LLPS-Dac-2166Daucus carota34.784e-1881.3
LLPS-Mua-2325Musa acuminata34.683e-1778.6
LLPS-Glm-2844Glycine max34.644e-1984.0
LLPS-Chc-0364Chondrus crispus34.482e-1779.7
LLPS-Cus-0426Cucumis sativus34.442e-1984.7
LLPS-Bro-0699Brassica oleracea34.429e-1880.1
LLPS-Brr-0040Brassica rapa34.421e-1780.9
LLPS-Tra-0627Triticum aestivum34.336e-1983.6
LLPS-Brd-0023Brachypodium distachyon34.333e-1780.1
LLPS-Hov-0731Hordeum vulgare34.333e-1882.8
LLPS-Tru-1374Triticum urartu34.331e-1883.6
LLPS-Gor-0330Gossypium raimondii34.212e-1985.1
LLPS-Cym-0268Cyanidioschyzon merolae33.561e-1677.8
LLPS-Asf-0507Aspergillus flavus32.916e-1778.2
LLPS-Thc-0491Theobroma cacao32.894e-1984.0
LLPS-Vir-0246Vigna radiata32.685e-1778.6
LLPS-Osl-0637Ostreococcus lucimarinus32.684e-1881.3
LLPS-Chr-0315Chlamydomonas reinhardtii31.392e-1679.0