• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mam-0946
TCP1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit alpha isoform a
Gene Name: TCP1
Ensembl Gene: ENSMMUG00000012846.3
Ensembl Protein: ENSMMUP00000032959.2
Organism: Macaca mulatta
Taxa ID: 9544
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEGPLSVFGD  RSTGEAIRSQ  NVMAAASIAN  IVKSSLGPVG  LDKMLVDDIG  DVTITNDGAT  60
61    ILKLLEVEHP  AAKVLCELAD  LQDKEVGDGT  TSVVIIAAEL  LKNADELVKQ  KIHPTSVISG  120
121   YRLACKEAVR  YINENLIVNT  DELGRDCLIN  AAKTSMSSKI  IGINGDFFAN  MVVDAVLAIK  180
181   YTDTRGQPRY  PVNSVNILKA  HGRSQMESML  ISGYALNCVV  GSQGMPKRIV  NAKIACLDFS  240
241   LQKTKMKLGV  QVVITDPEKL  DQIRQRESDI  TKERIQKILA  TGANVILTTG  GIDDMCLKYF  300
301   VEAGAMAVRR  VLKRDLKRIA  KASGATILST  LANLEGEETF  EAAMLGQAEE  VVQERICDDE  360
361   LILIKNTKAR  TSASIILRGA  NDFMCDEMER  SLHDALCVVK  RVLESKSVVP  GGGAVEAALS  420
421   IYLENYATSM  GSREQLAIAE  FARSLLVIPN  TLAVNAAQDS  TDLVAKLRAF  HNEAQVNPER  480
481   KNLKWIGLDL  SNGKPRDNKQ  AGVFEPTIVK  VKSLKFATEA  AITILRIDDL  IKLHPESKDD  540
541   KHGSYEDAVH  SGALND  556
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGGGC  CTTTGTCCGT  GTTCGGTGAC  CGCAGCACTG  GGGAAGCGAT  CCGCTCCCAG  60
61    AACGTTATGG  CTGCAGCTTC  GATTGCCAAT  ATTGTAAAAA  GTTCTCTTGG  TCCTGTTGGC  120
121   TTGGATAAAA  TGCTGGTGGA  TGATATCGGT  GATGTGACCA  TTACTAACGA  TGGTGCAACC  180
181   ATCCTCAAGT  TACTGGAAGT  TGAACATCCT  GCAGCTAAAG  TTCTTTGTGA  GCTGGCTGAT  240
241   CTGCAAGACA  AAGAAGTTGG  AGATGGAACT  ACATCAGTGG  TTATTATTGC  CGCAGAACTC  300
301   CTAAAAAATG  CAGATGAATT  AGTCAAACAG  AAAATTCATC  CCACATCAGT  TATTAGTGGC  360
361   TATCGACTTG  CTTGCAAGGA  AGCAGTGCGT  TATATCAATG  AAAACCTAAT  TGTTAACACA  420
421   GATGAACTGG  GAAGAGATTG  CCTGATTAAT  GCTGCTAAGA  CATCCATGTC  TTCCAAAATC  480
481   ATTGGAATAA  ATGGTGATTT  CTTTGCTAAC  ATGGTAGTAG  ATGCTGTACT  TGCTATTAAA  540
541   TACACAGACA  CAAGAGGCCA  GCCACGCTAT  CCAGTCAATT  CTGTTAATAT  TTTGAAAGCC  600
601   CATGGGAGAA  GTCAAATGGA  GAGTATGCTC  ATCAGTGGCT  ATGCACTCAA  CTGTGTGGTG  660
661   GGATCCCAGG  GCATGCCCAA  GAGAATCGTA  AATGCAAAAA  TTGCTTGCCT  TGACTTTAGC  720
721   CTGCAAAAAA  CAAAAATGAA  GCTTGGTGTA  CAGGTGGTCA  TTACAGACCC  TGAAAAACTG  780
781   GACCAAATTA  GACAGAGAGA  ATCAGATATC  ACCAAGGAGA  GAATTCAGAA  GATCCTGGCG  840
841   ACTGGTGCCA  ATGTTATTCT  AACCACTGGT  GGAATTGATG  ATATGTGTCT  GAAGTATTTT  900
901   GTGGAGGCTG  GTGCTATGGC  AGTTAGAAGA  GTTTTAAAAA  GGGACCTTAA  ACGCATTGCG  960
961   AAAGCTTCTG  GAGCAACTAT  TCTGTCAACC  CTGGCCAATT  TGGAAGGTGA  AGAAACTTTT  1020
1021  GAAGCTGCAA  TGTTGGGACA  GGCAGAAGAA  GTGGTACAGG  AGAGAATTTG  TGATGATGAG  1080
1081  CTGATCTTAA  TCAAAAACAC  TAAGGCTCGT  ACATCTGCAT  CGATTATCTT  ACGTGGGGCA  1140
1141  AATGATTTCA  TGTGTGATGA  GATGGAGCGC  TCGTTACATG  ATGCACTTTG  TGTAGTGAAG  1200
1201  AGAGTTTTGG  AGTCAAAATC  CGTGGTTCCC  GGTGGAGGTG  CTGTAGAAGC  AGCCCTTTCC  1260
1261  ATATACCTTG  AAAACTATGC  AACCAGCATG  GGGTCTCGGG  AACAGCTTGC  TATTGCAGAG  1320
1321  TTTGCAAGAT  CACTTCTTGT  TATTCCCAAT  ACACTAGCAG  TTAATGCTGC  CCAGGACTCC  1380
1381  ACAGATCTGG  TTGCAAAATT  AAGAGCTTTT  CATAATGAGG  CTCAGGTTAA  CCCAGAACGT  1440
1441  AAAAATCTAA  AATGGATTGG  TCTTGATTTG  AGCAATGGTA  AACCTCGAGA  CAACAAACAA  1500
1501  GCAGGGGTGT  TTGAACCAAC  CATAGTTAAA  GTTAAGAGTT  TGAAATTTGC  AACAGAAGCT  1560
1561  GCAATTACCA  TTCTTCGAAT  TGATGATCTT  ATTAAATTAC  ATCCAGAAAG  TAAAGATGAT  1620
1621  AAACATGGAA  GTTATGAAGA  TGCTGTTCAC  TCTGGAGCCC  TTAATGATTG  A  1671

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Maf-0509Macaca fascicularis100.00.01133
LLPS-Aon-2145Aotus nancymaae100.00.01133
LLPS-Man-1961Macaca nemestrina100.00.01133
LLPS-Chs-1308Chlorocebus sabaeus99.820.01130
LLPS-Cea-0963Cercocebus atys99.820.01130
LLPS-Mal-0360Mandrillus leucophaeus99.820.01130
LLPS-Rhb-0641Rhinopithecus bieti99.820.01130
LLPS-Gog-3605Gorilla gorilla99.640.01129
LLPS-Pat-0926Pan troglodytes99.640.01129
LLPS-Hos-0253Homo sapiens99.640.01129
LLPS-Nol-1006Nomascus leucogenys99.640.01129
LLPS-Poa-0723Pongo abelii99.640.01129
LLPS-Caj-0524Callithrix jacchus99.460.01126
LLPS-Pap-1057Pan paniscus99.460.01122
LLPS-Cas-1323Carlito syrichta98.560.01118
LLPS-Mea-1804Mesocricetus auratus97.940.0 580
LLPS-Sus-0935Sus scrofa97.840.01113
LLPS-Ova-1108Ovis aries97.840.01114
LLPS-Otg-0074Otolemur garnettii97.840.01113
LLPS-Fec-0751Felis catus97.840.01113
LLPS-Caf-3103Canis familiaris97.840.01113
LLPS-Ran-2181Rattus norvegicus97.660.01107
LLPS-Ict-3100Ictidomys tridecemlineatus97.660.01110
LLPS-Mup-0318Mustela putorius furo97.480.01110
LLPS-Bot-2420Bos taurus97.480.01111
LLPS-Eqc-1793Equus caballus97.480.01110
LLPS-Urm-0158Ursus maritimus97.30.01108
LLPS-Loa-1371Loxodonta africana97.30.01109
LLPS-Cap-0499Cavia porcellus97.30.01107
LLPS-Paa-1515Papio anubis97.120.01082
LLPS-Fud-2443Fukomys damarensis96.770.01104
LLPS-Dio-0039Dipodomys ordii96.770.01101
LLPS-Mum-4277Mus musculus96.580.01100
LLPS-Tut-0472Tursiops truncatus96.080.0 801
LLPS-Aim-1161Ailuropoda melanoleuca96.050.01092
LLPS-Myl-0116Myotis lucifugus95.50.01095
LLPS-Ora-0269Ornithorhynchus anatinus95.330.01044
LLPS-Mod-0838Monodelphis domestica94.870.0 953
LLPS-Sah-2679Sarcophilus harrisii93.540.0 558
LLPS-Pes-2360Pelodiscus sinensis93.260.01023
LLPS-Tag-1839Taeniopygia guttata92.770.0 632
LLPS-Fia-1313Ficedula albicollis91.620.0 975
LLPS-Anc-1780Anolis carolinensis91.450.01022
LLPS-Anp-2968Anas platyrhynchos91.40.01011
LLPS-Meg-0442Meleagris gallopavo91.010.01047
LLPS-Gaga-0409Gallus gallus90.910.01010
LLPS-Lac-0267Latimeria chalumnae89.350.01030
LLPS-Leo-2957Lepisosteus oculatus88.090.01009
LLPS-Asm-1813Astyanax mexicanus87.730.01006
LLPS-Scf-1648Scleropages formosus87.590.01004
LLPS-Orn-0366Oreochromis niloticus87.390.01008
LLPS-Xim-0723Xiphophorus maculatus87.210.01001
LLPS-Pof-1211Poecilia formosa87.210.01001
LLPS-Scm-0584Scophthalmus maximus87.050.01003
LLPS-Icp-1551Ictalurus punctatus87.00.01000
LLPS-Dar-1839Danio rerio87.00.01000
LLPS-Ten-1405Tetraodon nigroviridis86.820.0 995
LLPS-Orl-0062Oryzias latipes86.640.0 997
LLPS-Tar-1242Takifugu rubripes86.640.0 993
LLPS-Gaa-2757Gasterosteus aculeatus85.560.0 991
LLPS-Cii-0888Ciona intestinalis74.550.0 859
LLPS-Drm-0954Drosophila melanogaster73.330.0 844
LLPS-Abg-0954Absidia glauca70.960.0 784
LLPS-Cae-0045Caenorhabditis elegans68.950.0 768
LLPS-Miv-0099Microbotryum violaceum68.760.0 756
LLPS-Sei-1428Setaria italica68.50.0 756
LLPS-Tra-2853Triticum aestivum68.30.0 763
LLPS-Php-1762Physcomitrella patens68.280.0 749
LLPS-Hea-2475Helianthus annuus68.160.0 766
LLPS-Scj-0684Schizosaccharomyces japonicus68.150.0 744
LLPS-Orni-0623Oryza nivara68.110.0 755
LLPS-Orb-0331Oryza barthii68.110.0 756
LLPS-Ori-1140Oryza indica68.110.0 755
LLPS-Orgl-0484Oryza glumaepatula68.110.0 755
LLPS-Ors-0072Oryza sativa68.110.0 756
LLPS-Orp-0004Oryza punctata68.110.0 756
LLPS-Zem-0463Zea mays68.110.0 755
LLPS-Org-1038Oryza glaberrima68.110.0 756
LLPS-Orm-0219Oryza meridionalis68.110.0 756
LLPS-Orr-0445Oryza rufipogon68.110.0 756
LLPS-Met-0640Medicago truncatula67.930.0 747
LLPS-Usm-0214Ustilago maydis67.710.0 746
LLPS-Sob-0493Sorghum bicolor67.660.0 758
LLPS-Lep-1290Leersia perrieri67.550.0 753
LLPS-Orbr-1504Oryza brachyantha67.550.0 753
LLPS-Tru-0400Triticum urartu67.550.0 746
LLPS-Coc-0143Corchorus capsularis67.550.0 756
LLPS-Spr-0185Sporisorium reilianum67.530.0 743
LLPS-Prp-1293Prunus persica67.480.0 750
LLPS-Hov-0493Hordeum vulgare67.410.0 699
LLPS-Glm-0223Glycine max67.360.0 744
LLPS-Brd-1677Brachypodium distachyon67.360.0 751
LLPS-Via-1780Vigna angularis67.360.0 747
LLPS-Sol-0827Solanum lycopersicum67.290.0 753
LLPS-Sot-0481Solanum tuberosum67.290.0 752
LLPS-Nia-0373Nicotiana attenuata67.230.0 751
LLPS-Viv-0791Vitis vinifera67.170.0 743
LLPS-Amt-0588Amborella trichopoda66.980.0 754
LLPS-Phv-1157Phaseolus vulgaris66.980.0 745
LLPS-Brn-3134Brassica napus66.850.0 746
LLPS-Cus-0228Cucumis sativus66.790.0 750
LLPS-Mae-0363Manihot esculenta66.790.0 756
LLPS-Gor-1560Gossypium raimondii66.790.0 747
LLPS-Thc-1151Theobroma cacao66.730.0 754
LLPS-Crn-0302Cryptococcus neoformans66.730.0 739
LLPS-Brr-2789Brassica rapa66.730.0 739
LLPS-Bro-0503Brassica oleracea66.670.0 744
LLPS-Art-0804Arabidopsis thaliana66.480.0 744
LLPS-Pot-0769Populus trichocarpa66.420.0 748
LLPS-Dac-0469Daucus carota66.360.0 745
LLPS-Arl-1064Arabidopsis lyrata66.290.0 741
LLPS-Tum-0083Tuber melanosporum66.00.0 678
LLPS-Scp-0300Schizosaccharomyces pombe66.00.0 727
LLPS-Sem-0101Selaginella moellendorffii65.860.0 742
LLPS-Scc-0092Schizosaccharomyces cryophilus65.810.0 727
LLPS-Chr-0542Chlamydomonas reinhardtii65.80.0 729
LLPS-Yal-0974Yarrowia lipolytica65.740.0 709
LLPS-Pug-0403Puccinia graminis65.670.0 713
LLPS-Mua-0459Musa acuminata65.50.0 749
LLPS-Mel-0520Melampsora laricipopulina64.920.0 716
LLPS-Put-0673Puccinia triticina64.690.0 691
LLPS-Vir-0205Vigna radiata64.150.0 701
LLPS-Phn-0312Phaeosphaeria nodorum64.150.0 707
LLPS-Pyt-0234Pyrenophora teres64.00.0 710
LLPS-Pytr-0390Pyrenophora triticirepentis64.00.0 710
LLPS-Lem-0161Leptosphaeria maculans63.820.0 704
LLPS-Sac-0240Saccharomyces cerevisiae63.770.0 700
LLPS-Asf-0152Aspergillus flavus63.220.0 707
LLPS-Aso-0528Aspergillus oryzae63.220.0 707
LLPS-Fus-0778Fusarium solani63.180.0 698
LLPS-Coo-0327Colletotrichum orbiculare63.060.0 701
LLPS-Cogr-0759Colletotrichum graminicola62.880.0 704
LLPS-Asfu-0259Aspergillus fumigatus62.860.0 702
LLPS-Kop-0347Komagataella pastoris62.830.0 691
LLPS-Asc-0969Aspergillus clavatus62.680.0 697
LLPS-Nef-0188Neosartorya fischeri62.680.0 698
LLPS-Osl-0404Ostreococcus lucimarinus62.480.0 682
LLPS-Nec-0001Neurospora crassa62.450.0 692
LLPS-Asni-0102Aspergillus niger62.410.0 700
LLPS-Ast-0070Aspergillus terreus62.410.0 693
LLPS-Ved-0245Verticillium dahliae62.410.0 696
LLPS-Mao-0169Magnaporthe oryzae62.340.0 699
LLPS-Map-0974Magnaporthe poae62.30.0 701
LLPS-Gag-0134Gaeumannomyces graminis62.30.0 699
LLPS-Fuv-0087Fusarium verticillioides62.270.0 695
LLPS-Fuo-1238Fusarium oxysporum62.090.0 692
LLPS-Asn-1093Aspergillus nidulans61.590.0 688
LLPS-Asg-0109Ashbya gossypii61.470.0 672
LLPS-Cog-0970Colletotrichum gloeosporioides61.191e-167 489
LLPS-Trv-0203Trichoderma virens60.90.0 679
LLPS-Trr-0228Trichoderma reesei60.540.0 679
LLPS-Beb-0953Beauveria bassiana60.290.0 673
LLPS-Scs-0440Sclerotinia sclerotiorum59.930.0 646
LLPS-Blg-0729Blumeria graminis59.820.0 680
LLPS-Chc-0188Chondrus crispus59.70.0 662
LLPS-Zyt-0615Zymoseptoria tritici59.480.0 674
LLPS-Gas-0017Galdieria sulphuraria59.330.0 675
LLPS-Dos-0164Dothistroma septosporum58.890.0 669
LLPS-Cym-0397Cyanidioschyzon merolae54.850.0 612
LLPS-Xet-0421Xenopus tropicalis37.625e-96 310