LLPS-Mal-a1102
VPS16
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Vacuolar protein sorting-associated protein 16 homolog |
| Gene Name: | VPS16 |
| Ensembl Gene: | ENSMLEG00000008392.1 |
| Ensembl Protein: | ENSMLEP00000002171.1 |
| Organism: | Mandrillus leucophaeus |
| Taxa ID: | 9568 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMLET00000009654.1 | ENSMLEP00000002171.1 |
| Ensembl | ENSMLET00000009640.1 | ENSMLEP00000002166.1 |
| Ensembl | ENSMLET00000009694.1 | ENSMLEP00000002178.1 |
| UniProt | A0A2K5XFU2, A0A2K5XFU2_MANLE | |
| RefSeq | XM_011974665.1 | XP_011830055.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDCYTANWNP LGDSAFYRKY ELYSMDWDLK EELRDCLVAA APYGGPIALL RNPWRKEKAA 60 61 SVRPVLDIYS ASGMPLASLL WKSGPVVSLG WSAEEELLCV QEDGAVLVYG LHGDFRRHFS 120 121 MGNEVLQNRV LDARIFHTEF GSGVAILTGA HRFTLSANVG DLKLRRMPEV PGLQSAPSCW 180 181 TVLCQDRVAH ILLAVGPDLY LLDHAACSAV TPPGLAPGVS SFLQMAVSFT YRHLALFTDT 240 241 GYIWMGTASL KEKLCEFNCN IRAPPKQMVW CSRPRSKERA VVVAWERRLM VVGDAPESIQ 300 301 FVLDEDSYLV PELDGVRIFS RSTHEFLHEV PAASEEIFKI ASMAPGALLL EAQKEYEKES 360 361 QKADEYLREI QELGQLTQAV QQCIEAAGHE HQPDMQKSLL RAASFGKCFL DRFPPDSFVH 420 421 MCQDLRVLNA VRDYHIGIPL TYSQYKQLTI QVLLDRLVLR RLYPLAIQIC EYLRLPEVQG 480 481 VSRILAHWAC YKVQQKDVSD EDVARAINQK LGDTPGVSYS DIAARAYGCG RTELAIKLLE 540 541 YEPRSGEQVP LLLKMKRSKL ALSKAIESGD TDLVFTVLLH LKNELNRGDF FMTLRNQPMA 600 601 LSLYRQFCKH QELETLKDLY NQDDNHQELG SFHIRASYAA EERIEGRVAA LQTAADAFYK 660 661 AKNEFAAKAT EDQMRLLRLQ RRLEDELGGQ FLDLSLHDTV TTLILGGHNK RAEQLARDFR 720 721 IPDKRLWWLK LTALADLEDW EELEKFSKSK KSPIGYLPFV EICMKQHNKY EAKKYASRVG 780 781 PEQKVKALLL VGDVAQAADV AIEHRNEAEL SLVLSHCTGA TDGATADKIQ RARAQAQKK 839 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | CORVET complex | |
Cellular Component | Early endosome | |
Cellular Component | HOPS complex | |
Cellular Component | Late endosome membrane | |
Cellular Component | Lysosomal membrane | |
Cellular Component | Recycling endosome | |
Biological Process | Autophagosome maturation | |
Biological Process | Endosome to lysosome transport | |
Biological Process | Intracellular protein transport | |
Biological Process | Vacuole organization |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a1150 | Homo sapiens | 0.0 | 1734 | undefined |
| LLPS-Mum-a1130 | Mus musculus | 0.0 | 1691 | undefined |