LLPS-Mal-a045
ATP6V0A1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | V-type proton ATPase subunit a |
| Gene Name: | ATP6V0A1 |
| Ensembl Gene: | ENSMLEG00000029939.1 |
| Ensembl Protein: | ENSMLEP00000011650.1 |
| Organism: | Mandrillus leucophaeus |
| Taxa ID: | 9568 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMLET00000035075.1 | ENSMLEP00000011650.1 |
| Ensembl | ENSMLET00000035070.1 | ENSMLEP00000011644.1 |
| UniProt | A0A2K5Y7X8, A0A2K5Y7X8_MANLE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE 60 61 MDRKLRMCTL ANFEKIENEL KEINTNQEAL KRNFLELTEL KFILRKTQQF FDEAELHHQQ 120 121 MADPDLLEES SSLLEPSEMG RGTPLRLGFV AGVINRERIP TFERMLWRVC RGNVFLRQAE 180 181 IENPLEDPVT GDYVHKSVFI IFFQGDQLKN RVKKICEGFR ASLYPCPETP QERKEMASGV 240 241 NTRIDDLQMV CRRLEGICFC TCSKPGYQKK KCPWIICPSG TLALLKRDRN EHSGSTVPSI 300 301 LNRMQTNQTP PTYNKTNKFT YGFQNIVDAY GIGTYREINP APYTIITFPF LFAVMFGDFG 360 361 HGILMTLFAV WMVLRESRIL SQKNENEMFS TVFSGRYIIL LMGVFSMYTG LIYNDCFSKS 420 421 LNIFGSSWSV RPMFTYNWTE ETLRGNPVLQ LNPALPGVFG GPYPFGIDPV RGLPSYILTS 480 481 NFLTKSSLVH LGVMTMLWSC FKNNYFKKPL NIYFGFIPEI IFMTSLFGYL VILIFYKWTA 540 541 YDAHTSENAP SLLIHFINMF LFSYPESGYS MLYSGQKGIQ CFLVVVALLC VPWMLLFKPL 600 601 VLRRQYLRRK HLGTLNFGGI RVGNGPTEED AEIIQHDQLS THSEDADEFD FGDTMVHQAI 660 661 HTIEYCLGCI SNTASYLRLW ALSLAHAQLS EVLWTMVIHI GLSVKSLAGG LALFFIFAAF 720 721 ATLTVAILLI MEGLSAFLHA LRLHWVEFQN KFYSGTGFKF LPFSFEHIRE GKFEE 775 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Golgi apparatus | |
Cellular Component | Integral component of membrane | |
Cellular Component | Nuclear speck | |
Cellular Component | Perinuclear region of cytoplasm | |
Cellular Component | Plasma membrane | |
Cellular Component | Vacuolar proton-transporting V-type ATPase, V0 domain | |
Molecular Function | ATPase binding | |
Molecular Function | Proton transmembrane transporter activity | |
Biological Process | ATP hydrolysis coupled proton transport | |
Biological Process | Regulation of macroautophagy | |
Biological Process | Toxin transport |